Planaria EST Database

DrC_00971

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00971
         (802 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8UWA5|CAH2_TRIHK  Carbonic anhydrase 2 (Carbonic anhydra...   143   5e-34
sp|Q92051|CAHZ_BRARE  Carbonic anhydrase (Carbonate dehydrat...   138   2e-32
sp|P00920|CAH2_MOUSE  Carbonic anhydrase 2 (Carbonic anhydra...   137   3e-32
sp|P00919|CAH2_RABIT  Carbonic anhydrase 2 (Carbonic anhydra...   137   3e-32
sp|P28651|CAH8_MOUSE  Carbonic anhydrase-related protein (CA...   135   1e-31
sp|P27139|CAH2_RAT  Carbonic anhydrase II (Carbonate dehydra...   135   1e-31
sp|P35219|CAH8_HUMAN  Carbonic anhydrase-related protein (CA...   135   2e-31
sp|Q7M316|CAH1_GORGO  Carbonic anhydrase I (Carbonate dehydr...   133   6e-31
sp|P35217|CAH1_MACNE  Carbonic anhydrase 1 (Carbonic anhydra...   132   1e-30
sp|P00915|CAH1_HUMAN  Carbonic anhydrase 1 (Carbonic anhydra...   131   2e-30

>sp|Q8UWA5|CAH2_TRIHK Carbonic anhydrase 2 (Carbonic anhydrase II) (Carbonate dehydratase
           II) (CA-II)
          Length = 260

 Score =  143 bits (361), Expect = 5e-34
 Identities = 82/204 (40%), Positives = 117/204 (57%), Gaps = 4/204 (1%)
 Frame = -3

Query: 800 GHSFKVEVGLDSMSVTGVPEHKGDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELHLV 621
           GHSF+V    D+ S           ++L QFHFHWG ++ G+GSEH ++GK +P ELHLV
Sbjct: 63  GHSFQVTFADDNDSSMLTEGPISGKYRLKQFHFHWGASD-GKGSEHTVDGKCYPAELHLV 121

Query: 620 HYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVRENPTINLHEKNAY 441
           H+N TKY+S  EA N+ DGL V+GV +QI   N   Q  +  + +++        + +  
Sbjct: 122 HWN-TKYASFGEAANKPDGLAVVGVFLQIGEDNPKLQKILDAMDAIKSKGK----QTSFT 176

Query: 440 XXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQNV----HCDD 273
                     +  Y+TY GSLTTPP  ESV WIV + PI++S EQ+ +F+++      + 
Sbjct: 177 NFDPTCLLPKSLEYWTYPGSLTTPPLYESVTWIVCKQPISVSSEQMKKFRSLLFTAEEEK 236

Query: 272 GCETHSNYRPVCPVNDRKVKRSFK 201
            C   +NYRP  P+ DRKV  SFK
Sbjct: 237 ACCMVNNYRPPQPLKDRKVCASFK 260

>sp|Q92051|CAHZ_BRARE Carbonic anhydrase (Carbonate dehydratase)
          Length = 260

 Score =  138 bits (348), Expect = 2e-32
 Identities = 83/208 (39%), Positives = 115/208 (55%), Gaps = 8/208 (3%)
 Frame = -3

Query: 800 GHSFKVEVGLDSMSVTGVPEHKGDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELHLV 621
           GHSF+V+   D  S T        +++L QFHFHWG++++ +GSEH I G  +PCELHLV
Sbjct: 63  GHSFQVDFVDDDNSSTLAGGPITGIYRLRQFHFHWGSSDD-KGSEHTIAGTKFPCELHLV 121

Query: 620 HYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSV----RENPTINLHE 453
           H+N TKY +  EA ++ DGL V+GV ++I   N   Q  +  L  +    R+    N   
Sbjct: 122 HWN-TKYPNFGEAASKPDGLAVVGVFLKIGAANPRLQKVLDALDDIKSKGRQTTFANFDP 180

Query: 452 KNAYXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQNVHCDD 273
           K                Y+TY GSLTTPP  ESV WIV + PI++S  Q+ +F+++    
Sbjct: 181 KTLLPASLD--------YWTYEGSLTTPPLLESVTWIVLKEPISVSPAQMAKFRSLLFSS 232

Query: 272 GCETH----SNYRPVCPVNDRKVKRSFK 201
             ET      NYRP  P+  RKV+ SFK
Sbjct: 233 EGETPCCMVDNYRPPQPLKGRKVRASFK 260

>sp|P00920|CAH2_MOUSE Carbonic anhydrase 2 (Carbonic anhydrase II) (Carbonate dehydratase
           II) (CA-II)
          Length = 260

 Score =  137 bits (346), Expect = 3e-32
 Identities = 83/206 (40%), Positives = 117/206 (56%), Gaps = 6/206 (2%)
 Frame = -3

Query: 800 GHSFKVEV--GLDSMSVTGVPEHKGDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELH 627
           GHSF VE     D+  + G P    D ++L+QFHFHWG+++ G+GSEH +N K +  ELH
Sbjct: 63  GHSFNVEFDDSQDNAVLKGGP--LSDSYRLIQFHFHWGSSD-GQGSEHTVNKKKYAAELH 119

Query: 626 LVHYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVRENPTINLHEKN 447
           LVH+N TKY    +AV + DGL VLG  ++I   +   Q  ++ L S++   T       
Sbjct: 120 LVHWN-TKYGDFGKAVQQPDGLAVLGYFLKIGPASQGLQKVLEALHSIK---TKGKRAAF 175

Query: 446 AYXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQNVHCDDGC 267
           A          N D Y+TY GSLTTPP  E V WIV   PIT+S EQ+  F+ ++ ++  
Sbjct: 176 ANFDPCSLLPGNLD-YWTYPGSLTTPPLLECVTWIVLREPITVSSEQMSHFRTLNFNEEG 234

Query: 266 ETH----SNYRPVCPVNDRKVKRSFK 201
           +       N+RP  P+ +RK+K SFK
Sbjct: 235 DAEEAMVDNWRPAQPLKNRKIKASFK 260

>sp|P00919|CAH2_RABIT Carbonic anhydrase 2 (Carbonic anhydrase II) (Carbonate dehydratase
           II) (CA-II)
          Length = 259

 Score =  137 bits (346), Expect = 3e-32
 Identities = 81/205 (39%), Positives = 118/205 (57%), Gaps = 6/205 (2%)
 Frame = -3

Query: 800 GHSFKVEVGLDSMSVTGVPEHKGD-VFKLVQFHFHWGNTENGEGSEHQINGKSWPCELHL 624
           GHSF VE   DS   T + E   +  ++L+QFHFHWG+++ G+GSEH +N K +  ELHL
Sbjct: 62  GHSFNVEFD-DSHDKTVLKEGPLEGTYRLIQFHFHWGSSD-GQGSEHTVNKKKYAAELHL 119

Query: 623 VHYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVR-ENPTINLHEKN 447
           VH+N TKY    +AV   DGL VLG+ ++I       Q  +  L S++ +  +++  + +
Sbjct: 120 VHWN-TKYGDFGKAVKHPDGLAVLGIFLKIGSATPGLQKVVDTLSSIKTKGKSVDFTDFD 178

Query: 446 AYXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQNVHCDDGC 267
                          Y+TY GSLTTPP  E V WIV + PIT+S EQ+L+F+N++ +   
Sbjct: 179 PRGLLPESLD-----YWTYPGSLTTPPLLECVTWIVLKEPITVSSEQMLKFRNLNFNKEA 233

Query: 266 ETH----SNYRPVCPVNDRKVKRSF 204
           E       N+RP  P+  R+VK SF
Sbjct: 234 EPEEPMVDNWRPTQPLKGRQVKASF 258

>sp|P28651|CAH8_MOUSE Carbonic anhydrase-related protein (CARP) (CA-VIII)
          Length = 291

 Score =  135 bits (341), Expect = 1e-31
 Identities = 76/213 (35%), Positives = 122/213 (57%), Gaps = 13/213 (6%)
 Frame = -3

Query: 800 GHSFKVEVGLDSMSV-TGVPEHKGDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELHL 624
           GH+  ++V L S SV +G P  +G  F+L +  FHWG  EN  GSEH +N K++P ELHL
Sbjct: 87  GHT--IQVILKSKSVLSGGPLPQGQEFELYEVRFHWGR-ENQRGSEHTVNFKAFPMELHL 143

Query: 623 VHYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVR---ENPTINLHE 453
           +H+NST + S+ EAV +  G+ ++ + +QI  +++  +   + LQ ++   ++ TI    
Sbjct: 144 IHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFN 203

Query: 452 KNAYXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQNVHCD- 276
            N               Y+ Y GSLT PPC+E V WI+F YP+T+SQ QI +F+ +    
Sbjct: 204 PNTLLPDPLLRD-----YWVYEGSLTIPPCSEGVTWILFRYPLTISQMQIEEFRRLRTHV 258

Query: 275 ------DGCE--THSNYRPVCPVNDRKVKRSFK 201
                 +GC+     N+RP  P++DR ++ +F+
Sbjct: 259 KGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ 291

>sp|P27139|CAH2_RAT Carbonic anhydrase II (Carbonate dehydratase II) (CA-II)
          Length = 260

 Score =  135 bits (340), Expect = 1e-31
 Identities = 83/205 (40%), Positives = 114/205 (55%), Gaps = 5/205 (2%)
 Frame = -3

Query: 800 GHSFKVEVGLDSMSVTGVPEHK-GDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELHL 624
           GHSF VE   DS     + E      ++L+QFHFHWG+++ G+GSEH +N K +  ELHL
Sbjct: 63  GHSFNVEFD-DSQDFAVLKEGPLSGSYRLIQFHFHWGSSD-GQGSEHTVNKKKYAAELHL 120

Query: 623 VHYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVRENPTINLHEKNA 444
           VH+N TKY    +AV   DGL VLG+ ++I   +   Q   + L S++   T       A
Sbjct: 121 VHWN-TKYGDFGKAVQHPDGLAVLGIFLKIGPASQGLQKITEALHSIK---TKGKRAAFA 176

Query: 443 YXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQNVHCDDGCE 264
                     N D Y+TY GSLTTPP  E V WIV + PIT+S EQ+  F+ ++ +   E
Sbjct: 177 NFDPCSLLPGNLD-YWTYPGSLTTPPLLECVTWIVLKEPITVSSEQMSHFRKLNFNSEGE 235

Query: 263 TH----SNYRPVCPVNDRKVKRSFK 201
                  N+RP  P+ +RK+K SFK
Sbjct: 236 AEELMVDNWRPAQPLKNRKIKASFK 260

>sp|P35219|CAH8_HUMAN Carbonic anhydrase-related protein (CARP) (CA-VIII)
          Length = 290

 Score =  135 bits (339), Expect = 2e-31
 Identities = 76/213 (35%), Positives = 122/213 (57%), Gaps = 13/213 (6%)
 Frame = -3

Query: 800 GHSFKVEVGLDSMSV-TGVPEHKGDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELHL 624
           GH+  ++V L S SV +G P  +G  F+L +  FHWG  EN  GSEH +N K++P ELHL
Sbjct: 86  GHT--IQVILKSKSVLSGGPLPQGHEFELYEVRFHWGR-ENQRGSEHTVNFKAFPMELHL 142

Query: 623 VHYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVR---ENPTINLHE 453
           +H+NST + S+ EAV +  G+ ++ + +QI  +++  +   + LQ ++   ++ TI    
Sbjct: 143 IHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFN 202

Query: 452 KNAYXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQNVHCD- 276
            N               Y+ Y GSLT PPC+E V WI+F YP+T+SQ QI +F+ +    
Sbjct: 203 PNTLLPDPLLRD-----YWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHV 257

Query: 275 ------DGCE--THSNYRPVCPVNDRKVKRSFK 201
                 +GC+     N+RP  P++DR ++ +F+
Sbjct: 258 KGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ 290

>sp|Q7M316|CAH1_GORGO Carbonic anhydrase I (Carbonate dehydratase I) (CA-I)
          Length = 261

 Score =  133 bits (334), Expect = 6e-31
 Identities = 82/209 (39%), Positives = 113/209 (54%), Gaps = 10/209 (4%)
 Frame = -3

Query: 800 GHSFKVEV-GLDSMSVT-GVPEHKGDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELH 627
           GHSF V     D+ SV  G P    D ++L QFHFHWG+T N  GSEH ++G  +  ELH
Sbjct: 64  GHSFHVTFEDNDNRSVLKGGP--LSDSYRLFQFHFHWGST-NEHGSEHTVDGVKYSAELH 120

Query: 626 LVHYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVREN----PTINL 459
           L H+NS KYSSL+EA ++ DGL V+GV++++   N   Q  +  LQ+++      P  N 
Sbjct: 121 LTHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKILDALQAIKTKGKRAPFTNF 180

Query: 458 HEKNAYXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQ---- 291
                              ++TY GSLT PP  ESV WI+ +  I++S EQ+ QF+    
Sbjct: 181 DPSTLLPSSLD--------FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLS 232

Query: 290 NVHCDDGCETHSNYRPVCPVNDRKVKRSF 204
           NV  D+      N RP  P+  R V+ SF
Sbjct: 233 NVEGDNAVPMQHNNRPTQPLKGRTVRASF 261

>sp|P35217|CAH1_MACNE Carbonic anhydrase 1 (Carbonic anhydrase I) (Carbonate dehydratase
           I) (CA-I)
          Length = 261

 Score =  132 bits (332), Expect = 1e-30
 Identities = 82/209 (39%), Positives = 116/209 (55%), Gaps = 10/209 (4%)
 Frame = -3

Query: 800 GHSFKVEV-GLDSMSVT-GVPEHKGDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELH 627
           GHSF V     D+ SV  G P    D ++L QFHFHWG++ N  GSEH ++G  +  ELH
Sbjct: 64  GHSFHVNFEDNDNRSVLKGGPF--SDSYRLFQFHFHWGSS-NEYGSEHTVDGVKYSSELH 120

Query: 626 LVHYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVREN----PTINL 459
           +VH+NS KYSSL+EAV++ DGL V+GV++++   N   Q  +  L +++      P  N 
Sbjct: 121 IVHWNSAKYSSLAEAVSKADGLAVIGVLMKVGEANPKLQKVLDALHAIKTKGKRAPFTNF 180

Query: 458 HEKNAYXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQ---- 291
                              ++TYSGSLT PP  ESV WI+ +  I++S EQ+ QF+    
Sbjct: 181 DPSTLLPSSLD--------FWTYSGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLS 232

Query: 290 NVHCDDGCETHSNYRPVCPVNDRKVKRSF 204
           NV  D+   +  N RP  P+  R V+ SF
Sbjct: 233 NVEGDNPVPSQRNNRPTQPLKGRTVRASF 261

>sp|P00915|CAH1_HUMAN Carbonic anhydrase 1 (Carbonic anhydrase I) (Carbonate dehydratase
           I) (CA-I)
          Length = 261

 Score =  131 bits (330), Expect = 2e-30
 Identities = 81/209 (38%), Positives = 113/209 (54%), Gaps = 10/209 (4%)
 Frame = -3

Query: 800 GHSFKVEV-GLDSMSVT-GVPEHKGDVFKLVQFHFHWGNTENGEGSEHQINGKSWPCELH 627
           GHSF V     D+ SV  G P    D ++L QFHFHWG+T N  GSEH ++G  +  ELH
Sbjct: 64  GHSFHVNFEDNDNRSVLKGGPF--SDSYRLFQFHFHWGST-NEHGSEHTVDGVKYSAELH 120

Query: 626 LVHYNSTKYSSLSEAVNETDGLLVLGVMIQIAGKNIDFQNFIQCLQSVREN----PTINL 459
           + H+NS KYSSL+EA ++ DGL V+GV++++   N   Q  +  LQ+++      P  N 
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180

Query: 458 HEKNAYXXXXXXXXXNTDRYFTYSGSLTTPPCNESVIWIVFEYPITMSQEQILQFQ---- 291
                              ++TY GSLT PP  ESV WI+ +  I++S EQ+ QF+    
Sbjct: 181 DPSTLLPSSLD--------FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLS 232

Query: 290 NVHCDDGCETHSNYRPVCPVNDRKVKRSF 204
           NV  D+      N RP  P+  R V+ SF
Sbjct: 233 NVEGDNAVPMQHNNRPTQPLKGRTVRASF 261

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,556,127
Number of Sequences: 369166
Number of extensions: 1561536
Number of successful extensions: 3593
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3308
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3422
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7570361805
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00971

  1. Dr_sW_024_I06
  2. Dr_sW_019_A05