Planaria EST Database


DrC_00966

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00966
         (922 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q28709|CD63_RABIT  CD63 antigen                                 75   3e-13
sp|P08962|CD63_HUMAN  CD63 antigen (Melanoma-associated anti...    71   5e-12
sp|P48509|CD151_HUMAN  Platelet-endothelial tetraspan antige...    70   6e-12
sp|P28648|CD63_RAT  CD63 antigen (AD1 antigen)                     70   8e-12
sp|Q9QZA6|CD151_RAT  Platelet endothelial tetraspan antigen ...    70   1e-11
sp|O35566|C151_MOUSE  Platelet-endothelial tetraspan antigen...    69   1e-11
sp|P41731|CD63_MOUSE  CD63 antigen                                 66   2e-10
sp|P61171|CD151_MACMU  Platelet-endothelial tetraspan antige...    65   3e-10
sp|Q9XSK2|CD63_BOVIN  CD63 antigen                                 65   3e-10
sp|O70401|TSN6_MOUSE  Tetraspanin-6 (Tspan-6) (Transmembrane...    65   3e-10
>sp|Q28709|CD63_RABIT CD63 antigen
          Length = 238

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 37/128 (28%), Positives = 62/128 (48%)
 Frame = +3

Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587
           V+++ V        +++++N Y  +  TA+++D +QK+F CCG  +  DW  +     T+
Sbjct: 106 VFRDKVMSEFNKDFRQQMQN-YSTDNQTALILDRMQKDFTCCGAANYTDW--ATIPGMTR 162

Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767
            R P SCC      C    N+KD+Y +GC                   LGIAF E+  ++
Sbjct: 163 DRVPDSCCVNVTSGCGVKFNVKDIYVEGCVEKIGLWLRKNVLVVAAAALGIAFVEVLGIV 222

Query: 768 CAFCLCRN 791
            A CL ++
Sbjct: 223 FACCLVKS 230
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491)
           (Lysosome-associated membrane glycoprotein 3) (LAMP-3)
           (Ocular melanoma-associated antigen) (OMA81H)
           (Granulophysin) (Tetraspanin-30) (Tspan-30)
          Length = 238

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 37/128 (28%), Positives = 63/128 (49%)
 Frame = +3

Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587
           V+++ V     +  ++++ N Y  N  TA ++D +Q +F CCG  +  DW+  K  + +K
Sbjct: 106 VFRDKVMSEFNNNFRQQMEN-YPKNNHTASILDRMQADFKCCGAANYTDWE--KIPSMSK 162

Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767
            R P SCC    V C  + N K ++++GC                   LGIAF E+  ++
Sbjct: 163 NRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIV 222

Query: 768 CAFCLCRN 791
            A CL ++
Sbjct: 223 FACCLVKS 230
>sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
           glycoprotein SFA-1) (CD151 antigen) (Tetraspanin-24)
           (Tspan-24)
          Length = 253

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 54/241 (22%), Positives = 95/241 (39%), Gaps = 9/241 (3%)
 Frame = +3

Query: 96  CGPKLAKCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESI--GNFSASRSLLXXXXX 269
           CG    K +L  +N  FWL+GL ++ +    L+ +   Y+  +  G + A+  +L     
Sbjct: 11  CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLA-LKSDYISLLASGTYLATAYILVVAGT 69

Query: 270 XXXXXXXXXXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGL 449
                            +E +                    GI+   Y   +   + + L
Sbjct: 70  VVMVTGVLGCCA---TFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENL 126

Query: 450 KEKIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKESKYSNQTK---QRYPSSCCK 614
           K+ +   Y  +   AV   +D LQ+ F CCG ++  DW++S++    +   +  P SCCK
Sbjct: 127 KDTMTRRYHQSGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCK 186

Query: 615 TSNVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCR 788
           T    C   ++  ++Y  E GC                 V +GIA  ++F +I   CL R
Sbjct: 187 TVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYR 246

Query: 789 N 791
           +
Sbjct: 247 S 247
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen)
          Length = 238

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 37/128 (28%), Positives = 60/128 (46%)
 Frame = +3

Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587
           V+++ V+   +   +++++N Y  +  TA ++D LQK   CCG  +  DW+  +     K
Sbjct: 106 VFRDQVKSEFSKSFQKQMQN-YLTDNKTATILDKLQKENKCCGASNYTDWE--RIPGMAK 162

Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767
            R P SCC    V C ND     ++  GC                G  LGIAF E+  +I
Sbjct: 163 DRVPDSCCINITVGCGNDFKESTIHTQGCVETIAAWLRKNVLLVAGAALGIAFVEVLGII 222

Query: 768 CAFCLCRN 791
            + CL ++
Sbjct: 223 FSCCLVKS 230
>sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen 3 (CD151 antigen)
          Length = 253

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 55/239 (23%), Positives = 93/239 (38%), Gaps = 7/239 (2%)
 Frame = +3

Query: 96  CGPKLAKCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESIGNFSASRSLLXXXXXXX 275
           CG    K +L  +N  FWL+GL ++ +    L+ +   Y+  + + S   +         
Sbjct: 11  CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLA-LKSDYISLLAS-STYLATAYILVVAG 68

Query: 276 XXXXXXXXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGLKE 455
                          +E +                    GI+  VY   +   + + LK+
Sbjct: 69  VVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKD 128

Query: 456 KIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKESKY--SNQTKQR-YPSSCCKTS 620
            +   Y  +    V   +D LQ+ F CCG ++  DW++S++  S +   R  P SCCKT 
Sbjct: 129 TMIKRYHQSGHEGVTNAVDKLQQEFHCCGSNNSRDWRDSEWIRSGEADSRVVPDSCCKTV 188

Query: 621 NVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCRN 791
              C   E+  ++Y  E GC                 V +GIA  ++F +I   CL R+
Sbjct: 189 VTGCGKREHASNIYKVEGGCITKLESFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
           glycoprotein SFA-1) (CD151 antigen)
          Length = 253

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 7/239 (2%)
 Frame = +3

Query: 96  CGPKLAKCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESIGNFSASRSLLXXXXXXX 275
           CG    K +L  +N  FWL+GL ++ +    L+ +   Y+  + + S   +         
Sbjct: 11  CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLA-LKSDYISLLAS-STYLATAYILVVAG 68

Query: 276 XXXXXXXXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGLKE 455
                          +E +                    GI+  VY   +   + + LK+
Sbjct: 69  VVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKD 128

Query: 456 KIRNNYEINTDTAV--LIDSLQKNFLCCGGDSKDDWKESKY--SNQTKQR-YPSSCCKTS 620
            +   Y  +    V   +D LQ+ F CCG ++  DW++S++  S +   R  P SCCKT 
Sbjct: 129 TMVKRYHQSGHEGVSSAVDKLQQEFHCCGSNNSQDWQDSEWIRSGEADSRVVPDSCCKTM 188

Query: 621 NVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCRN 791
              C   ++  ++Y  E GC                 V +GIA  ++F +I   CL R+
Sbjct: 189 VAGCGKRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|P41731|CD63_MOUSE CD63 antigen
          Length = 238

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 36/128 (28%), Positives = 57/128 (44%)
 Frame = +3

Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587
           V+++ V+       +++++N Y  +  TA ++D LQK   CCG  +  DW+        K
Sbjct: 106 VFRDQVKSEFNKSFQQQMQN-YLKDNKTATILDKLQKENNCCGASNYTDWE--NIPGMAK 162

Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767
            R P SCC    V C ND     ++  GC                   LGIAF E+  +I
Sbjct: 163 DRVPDSCCINITVGCGNDFKESTIHTQGCVETIAIWLRKNILLVAAAALGIAFVEVLGII 222

Query: 768 CAFCLCRN 791
            + CL ++
Sbjct: 223 FSCCLVKS 230
>sp|P61171|CD151_MACMU Platelet-endothelial tetraspan antigen 3 (PETA-3) (CD151 antigen)
 sp|P61170|CD151_CERAE Platelet-endothelial tetraspan antigen 3 (PETA-3) (CD151 antigen)
          Length = 253

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 54/241 (22%), Positives = 93/241 (38%), Gaps = 9/241 (3%)
 Frame = +3

Query: 96  CGPKLAKCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESI--GNFSASRSLLXXXXX 269
           CG    K +L  +N  FWL+GL ++ +    L+ +   Y+  +  G + A+  +L     
Sbjct: 11  CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLA-LKSDYISLLASGTYLATAYILVVAGA 69

Query: 270 XXXXXXXXXXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGL 449
                            +E +                    G++  VY   +   + + L
Sbjct: 70  VVMVTGVLGCCA---TFKERRNLLRLYFILLLIIFLLEIIAGVLAYVYYQQLNTELKENL 126

Query: 450 KEKIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKESKYSNQTKQR---YPSSCCK 614
           K+ +   Y      AV   +D LQ+ F CCG ++  DW++S++    + R    P SCCK
Sbjct: 127 KDTMAKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRLREARGRVVPDSCCK 186

Query: 615 TSNVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCR 788
           T    C   ++  ++Y  E G                  V  GIA  ++F +I   CL R
Sbjct: 187 TVVAGCGQRDHAFNIYKVEGGFITKLETFIQEHLRVIGAVGTGIACVQVFGMIFTCCLYR 246

Query: 789 N 791
           +
Sbjct: 247 S 247
>sp|Q9XSK2|CD63_BOVIN CD63 antigen
          Length = 237

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 33/128 (25%), Positives = 60/128 (46%)
 Frame = +3

Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587
           V+++ V        +++++N Y  +  TA ++D +QK+F CCG  +  DW++        
Sbjct: 106 VFRDKVRSEFNKDFRQQMKN-YPKDNQTASILDKMQKDFECCGAANYTDWEKIL---AVT 161

Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767
            + P SCC      C  +  +KD++ +GC                   LGIAF E+  ++
Sbjct: 162 NKVPDSCCVNITHNCGINFVVKDIHTEGCVEKIAAWLRKNVLVVVAAALGIAFVEILGIV 221

Query: 768 CAFCLCRN 791
            A CL ++
Sbjct: 222 LACCLVKS 229
>sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
          Length = 245

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 43/225 (19%), Positives = 87/225 (38%)
 Frame = +3

Query: 114 KCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESIGNFSASRSLLXXXXXXXXXXXXX 293
           K +L+++  +FW++G+I++ +   +   V+++   S+ N  A+ ++              
Sbjct: 18  KSVLLIYTFIFWITGVILLAVG--IWGKVSLENYFSLLNEKAT-NVPFVLIGTGTVIILL 74

Query: 294 XXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGLKEKIRNNY 473
                    R S                      IV  V+++ ++       +  ++   
Sbjct: 75  GTFGCFATCRTSAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYN 134

Query: 474 EINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTKQRYPSSCCKTSNVTCWNDENIK 653
                 +  +D +Q    CCG  +  DWK + Y ++T   +P SCCK     C+   +  
Sbjct: 135 STGDYRSEAVDKIQSTLHCCGVTNYGDWKGTNYYSET--GFPKSCCKLEG--CYPQRDAD 190

Query: 654 DVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCR 788
            V E+GC                G+  G+A F++  +  A+CL R
Sbjct: 191 KVNEEGCFIKVMTTIESEMGVVAGISFGVACFQLIGIFLAYCLSR 235
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,952,552
Number of Sequences: 369166
Number of extensions: 1906835
Number of successful extensions: 4504
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4336
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4474
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9414689480
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00966

  1. Dr_sW_024_F14
  2. Dr_sW_002_O23