DrC_00966
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00966 (922 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q28709|CD63_RABIT CD63 antigen 75 3e-13 sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 71 5e-12 sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antige... 70 6e-12 sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) 70 8e-12 sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen ... 70 1e-11 sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen... 69 1e-11 sp|P41731|CD63_MOUSE CD63 antigen 66 2e-10 sp|P61171|CD151_MACMU Platelet-endothelial tetraspan antige... 65 3e-10 sp|Q9XSK2|CD63_BOVIN CD63 antigen 65 3e-10 sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane... 65 3e-10
>sp|Q28709|CD63_RABIT CD63 antigen Length = 238 Score = 74.7 bits (182), Expect = 3e-13 Identities = 37/128 (28%), Positives = 62/128 (48%) Frame = +3 Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587 V+++ V +++++N Y + TA+++D +QK+F CCG + DW + T+ Sbjct: 106 VFRDKVMSEFNKDFRQQMQN-YSTDNQTALILDRMQKDFTCCGAANYTDW--ATIPGMTR 162 Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767 R P SCC C N+KD+Y +GC LGIAF E+ ++ Sbjct: 163 DRVPDSCCVNVTSGCGVKFNVKDIYVEGCVEKIGLWLRKNVLVVAAAALGIAFVEVLGIV 222 Query: 768 CAFCLCRN 791 A CL ++ Sbjct: 223 FACCLVKS 230
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491) (Lysosome-associated membrane glycoprotein 3) (LAMP-3) (Ocular melanoma-associated antigen) (OMA81H) (Granulophysin) (Tetraspanin-30) (Tspan-30) Length = 238 Score = 70.9 bits (172), Expect = 5e-12 Identities = 37/128 (28%), Positives = 63/128 (49%) Frame = +3 Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587 V+++ V + ++++ N Y N TA ++D +Q +F CCG + DW+ K + +K Sbjct: 106 VFRDKVMSEFNNNFRQQMEN-YPKNNHTASILDRMQADFKCCGAANYTDWE--KIPSMSK 162 Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767 R P SCC V C + N K ++++GC LGIAF E+ ++ Sbjct: 163 NRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIV 222 Query: 768 CAFCLCRN 791 A CL ++ Sbjct: 223 FACCLVKS 230
>sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane glycoprotein SFA-1) (CD151 antigen) (Tetraspanin-24) (Tspan-24) Length = 253 Score = 70.5 bits (171), Expect = 6e-12 Identities = 54/241 (22%), Positives = 95/241 (39%), Gaps = 9/241 (3%) Frame = +3 Query: 96 CGPKLAKCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESI--GNFSASRSLLXXXXX 269 CG K +L +N FWL+GL ++ + L+ + Y+ + G + A+ +L Sbjct: 11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLA-LKSDYISLLASGTYLATAYILVVAGT 69 Query: 270 XXXXXXXXXXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGL 449 +E + GI+ Y + + + L Sbjct: 70 VVMVTGVLGCCA---TFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENL 126 Query: 450 KEKIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKESKYSNQTK---QRYPSSCCK 614 K+ + Y + AV +D LQ+ F CCG ++ DW++S++ + + P SCCK Sbjct: 127 KDTMTRRYHQSGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCK 186 Query: 615 TSNVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCR 788 T C ++ ++Y E GC V +GIA ++F +I CL R Sbjct: 187 TVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYR 246 Query: 789 N 791 + Sbjct: 247 S 247
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) Length = 238 Score = 70.1 bits (170), Expect = 8e-12 Identities = 37/128 (28%), Positives = 60/128 (46%) Frame = +3 Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587 V+++ V+ + +++++N Y + TA ++D LQK CCG + DW+ + K Sbjct: 106 VFRDQVKSEFSKSFQKQMQN-YLTDNKTATILDKLQKENKCCGASNYTDWE--RIPGMAK 162 Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767 R P SCC V C ND ++ GC G LGIAF E+ +I Sbjct: 163 DRVPDSCCINITVGCGNDFKESTIHTQGCVETIAAWLRKNVLLVAGAALGIAFVEVLGII 222 Query: 768 CAFCLCRN 791 + CL ++ Sbjct: 223 FSCCLVKS 230
>sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen 3 (CD151 antigen) Length = 253 Score = 69.7 bits (169), Expect = 1e-11 Identities = 55/239 (23%), Positives = 93/239 (38%), Gaps = 7/239 (2%) Frame = +3 Query: 96 CGPKLAKCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESIGNFSASRSLLXXXXXXX 275 CG K +L +N FWL+GL ++ + L+ + Y+ + + S + Sbjct: 11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLA-LKSDYISLLAS-STYLATAYILVVAG 68 Query: 276 XXXXXXXXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGLKE 455 +E + GI+ VY + + + LK+ Sbjct: 69 VVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKD 128 Query: 456 KIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKESKY--SNQTKQR-YPSSCCKTS 620 + Y + V +D LQ+ F CCG ++ DW++S++ S + R P SCCKT Sbjct: 129 TMIKRYHQSGHEGVTNAVDKLQQEFHCCGSNNSRDWRDSEWIRSGEADSRVVPDSCCKTV 188 Query: 621 NVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCRN 791 C E+ ++Y E GC V +GIA ++F +I CL R+ Sbjct: 189 VTGCGKREHASNIYKVEGGCITKLESFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane glycoprotein SFA-1) (CD151 antigen) Length = 253 Score = 69.3 bits (168), Expect = 1e-11 Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 7/239 (2%) Frame = +3 Query: 96 CGPKLAKCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESIGNFSASRSLLXXXXXXX 275 CG K +L +N FWL+GL ++ + L+ + Y+ + + S + Sbjct: 11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLA-LKSDYISLLAS-STYLATAYILVVAG 68 Query: 276 XXXXXXXXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGLKE 455 +E + GI+ VY + + + LK+ Sbjct: 69 VVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKD 128 Query: 456 KIRNNYEINTDTAV--LIDSLQKNFLCCGGDSKDDWKESKY--SNQTKQR-YPSSCCKTS 620 + Y + V +D LQ+ F CCG ++ DW++S++ S + R P SCCKT Sbjct: 129 TMVKRYHQSGHEGVSSAVDKLQQEFHCCGSNNSQDWQDSEWIRSGEADSRVVPDSCCKTM 188 Query: 621 NVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCRN 791 C ++ ++Y E GC V +GIA ++F +I CL R+ Sbjct: 189 VAGCGKRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|P41731|CD63_MOUSE CD63 antigen Length = 238 Score = 65.9 bits (159), Expect = 2e-10 Identities = 36/128 (28%), Positives = 57/128 (44%) Frame = +3 Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587 V+++ V+ +++++N Y + TA ++D LQK CCG + DW+ K Sbjct: 106 VFRDQVKSEFNKSFQQQMQN-YLKDNKTATILDKLQKENNCCGASNYTDWE--NIPGMAK 162 Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767 R P SCC V C ND ++ GC LGIAF E+ +I Sbjct: 163 DRVPDSCCINITVGCGNDFKESTIHTQGCVETIAIWLRKNILLVAAAALGIAFVEVLGII 222 Query: 768 CAFCLCRN 791 + CL ++ Sbjct: 223 FSCCLVKS 230
>sp|P61171|CD151_MACMU Platelet-endothelial tetraspan antigen 3 (PETA-3) (CD151 antigen) sp|P61170|CD151_CERAE Platelet-endothelial tetraspan antigen 3 (PETA-3) (CD151 antigen) Length = 253 Score = 65.1 bits (157), Expect = 3e-10 Identities = 54/241 (22%), Positives = 93/241 (38%), Gaps = 9/241 (3%) Frame = +3 Query: 96 CGPKLAKCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESI--GNFSASRSLLXXXXX 269 CG K +L +N FWL+GL ++ + L+ + Y+ + G + A+ +L Sbjct: 11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLA-LKSDYISLLASGTYLATAYILVVAGA 69 Query: 270 XXXXXXXXXXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGL 449 +E + G++ VY + + + L Sbjct: 70 VVMVTGVLGCCA---TFKERRNLLRLYFILLLIIFLLEIIAGVLAYVYYQQLNTELKENL 126 Query: 450 KEKIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKESKYSNQTKQR---YPSSCCK 614 K+ + Y AV +D LQ+ F CCG ++ DW++S++ + R P SCCK Sbjct: 127 KDTMAKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRLREARGRVVPDSCCK 186 Query: 615 TSNVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCR 788 T C ++ ++Y E G V GIA ++F +I CL R Sbjct: 187 TVVAGCGQRDHAFNIYKVEGGFITKLETFIQEHLRVIGAVGTGIACVQVFGMIFTCCLYR 246 Query: 789 N 791 + Sbjct: 247 S 247
>sp|Q9XSK2|CD63_BOVIN CD63 antigen Length = 237 Score = 64.7 bits (156), Expect = 3e-10 Identities = 33/128 (25%), Positives = 60/128 (46%) Frame = +3 Query: 408 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 587 V+++ V +++++N Y + TA ++D +QK+F CCG + DW++ Sbjct: 106 VFRDKVRSEFNKDFRQQMKN-YPKDNQTASILDKMQKDFECCGAANYTDWEKIL---AVT 161 Query: 588 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 767 + P SCC C + +KD++ +GC LGIAF E+ ++ Sbjct: 162 NKVPDSCCVNITHNCGINFVVKDIHTEGCVEKIAAWLRKNVLVVVAAALGIAFVEILGIV 221 Query: 768 CAFCLCRN 791 A CL ++ Sbjct: 222 LACCLVKS 229
>sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6) Length = 245 Score = 64.7 bits (156), Expect = 3e-10 Identities = 43/225 (19%), Positives = 87/225 (38%) Frame = +3 Query: 114 KCILILFNLVFWLSGLIMIVIASMLLSSVTMKYVESIGNFSASRSLLXXXXXXXXXXXXX 293 K +L+++ +FW++G+I++ + + V+++ S+ N A+ ++ Sbjct: 18 KSVLLIYTFIFWITGVILLAVG--IWGKVSLENYFSLLNEKAT-NVPFVLIGTGTVIILL 74 Query: 294 XXXXXXXAIRESKMXXXXXXXXXXXXXXXXXXXGIVVIVYKNSVEGRITDGLKEKIRNNY 473 R S IV V+++ ++ + ++ Sbjct: 75 GTFGCFATCRTSAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYN 134 Query: 474 EINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTKQRYPSSCCKTSNVTCWNDENIK 653 + +D +Q CCG + DWK + Y ++T +P SCCK C+ + Sbjct: 135 STGDYRSEAVDKIQSTLHCCGVTNYGDWKGTNYYSET--GFPKSCCKLEG--CYPQRDAD 190 Query: 654 DVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVICAFCLCR 788 V E+GC G+ G+A F++ + A+CL R Sbjct: 191 KVNEEGCFIKVMTTIESEMGVVAGISFGVACFQLIGIFLAYCLSR 235
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,952,552
Number of Sequences: 369166
Number of extensions: 1906835
Number of successful extensions: 4504
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4336
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4474
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9414689480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
