Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_O23
(593 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q28709|CD63_RABIT CD63 antigen 75 2e-13
sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 71 2e-12
sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) 70 4e-12
sp|P41731|CD63_MOUSE CD63 antigen 66 7e-11
sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen ... 65 2e-10
sp|Q9XSK2|CD63_BOVIN CD63 antigen 65 2e-10
sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen... 64 2e-10
sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antige... 64 2e-10
sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane... 60 3e-09
sp|P61171|CD151_MACMU Platelet-endothelial tetraspan antige... 59 9e-09
>sp|Q28709|CD63_RABIT CD63 antigen
Length = 238
Score = 74.7 bits (182), Expect = 2e-13
Identities = 37/128 (28%), Positives = 62/128 (48%)
Frame = +1
Query: 79 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 258
V+++ V +++++N Y + TA+++D +QK+F CCG + DW + T+
Sbjct: 106 VFRDKVMSEFNKDFRQQMQN-YSTDNQTALILDRMQKDFTCCGAANYTDW--ATIPGMTR 162
Query: 259 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 438
R P SCC C N+KD+Y +GC LGIAF E+ ++
Sbjct: 163 DRVPDSCCVNVTSGCGVKFNVKDIYVEGCVEKIGLWLRKNVLVVAAAALGIAFVEVLGIV 222
Query: 439 CAFCLCRN 462
A CL ++
Sbjct: 223 FACCLVKS 230
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491)
(Lysosome-associated membrane glycoprotein 3) (LAMP-3)
(Ocular melanoma-associated antigen) (OMA81H)
(Granulophysin) (Tetraspanin-30) (Tspan-30)
Length = 238
Score = 70.9 bits (172), Expect = 2e-12
Identities = 37/128 (28%), Positives = 63/128 (49%)
Frame = +1
Query: 79 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 258
V+++ V + ++++ N Y N TA ++D +Q +F CCG + DW+ K + +K
Sbjct: 106 VFRDKVMSEFNNNFRQQMEN-YPKNNHTASILDRMQADFKCCGAANYTDWE--KIPSMSK 162
Query: 259 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 438
R P SCC V C + N K ++++GC LGIAF E+ ++
Sbjct: 163 NRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIV 222
Query: 439 CAFCLCRN 462
A CL ++
Sbjct: 223 FACCLVKS 230
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen)
Length = 238
Score = 70.1 bits (170), Expect = 4e-12
Identities = 37/128 (28%), Positives = 60/128 (46%)
Frame = +1
Query: 79 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 258
V+++ V+ + +++++N Y + TA ++D LQK CCG + DW+ + K
Sbjct: 106 VFRDQVKSEFSKSFQKQMQN-YLTDNKTATILDKLQKENKCCGASNYTDWE--RIPGMAK 162
Query: 259 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 438
R P SCC V C ND ++ GC G LGIAF E+ +I
Sbjct: 163 DRVPDSCCINITVGCGNDFKESTIHTQGCVETIAAWLRKNVLLVAGAALGIAFVEVLGII 222
Query: 439 CAFCLCRN 462
+ CL ++
Sbjct: 223 FSCCLVKS 230
>sp|P41731|CD63_MOUSE CD63 antigen
Length = 238
Score = 65.9 bits (159), Expect = 7e-11
Identities = 36/128 (28%), Positives = 57/128 (44%)
Frame = +1
Query: 79 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 258
V+++ V+ +++++N Y + TA ++D LQK CCG + DW+ K
Sbjct: 106 VFRDQVKSEFNKSFQQQMQN-YLKDNKTATILDKLQKENNCCGASNYTDWE--NIPGMAK 162
Query: 259 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 438
R P SCC V C ND ++ GC LGIAF E+ +I
Sbjct: 163 DRVPDSCCINITVGCGNDFKESTIHTQGCVETIAIWLRKNILLVAAAALGIAFVEVLGII 222
Query: 439 CAFCLCRN 462
+ CL ++
Sbjct: 223 FSCCLVKS 230
>sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen 3 (CD151 antigen)
Length = 253
Score = 64.7 bits (156), Expect = 2e-10
Identities = 41/140 (29%), Positives = 65/140 (46%), Gaps = 7/140 (5%)
Frame = +1
Query: 64 GIVVIVYKNSVEGRITDGLKEKIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKES 237
GI+ VY + + + LK+ + Y + V +D LQ+ F CCG ++ DW++S
Sbjct: 108 GILAYVYYQQLNTELKENLKDTMIKRYHQSGHEGVTNAVDKLQQEFHCCGSNNSRDWRDS 167
Query: 238 KY--SNQTKQR-YPSSCCKTSNVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVL 402
++ S + R P SCCKT C E+ ++Y E GC V
Sbjct: 168 EWIRSGEADSRVVPDSCCKTVVTGCGKREHASNIYKVEGGCITKLESFIQEHLRVIGAVG 227
Query: 403 LGIAFFEMFVVICAFCLCRN 462
+GIA ++F +I CL R+
Sbjct: 228 IGIACVQVFGMIFTCCLYRS 247
>sp|Q9XSK2|CD63_BOVIN CD63 antigen
Length = 237
Score = 64.7 bits (156), Expect = 2e-10
Identities = 33/128 (25%), Positives = 60/128 (46%)
Frame = +1
Query: 79 VYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYSNQTK 258
V+++ V +++++N Y + TA ++D +QK+F CCG + DW++
Sbjct: 106 VFRDKVRSEFNKDFRQQMKN-YPKDNQTASILDKMQKDFECCGAANYTDWEKIL---AVT 161
Query: 259 QRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEMFVVI 438
+ P SCC C + +KD++ +GC LGIAF E+ ++
Sbjct: 162 NKVPDSCCVNITHNCGINFVVKDIHTEGCVEKIAAWLRKNVLVVVAAALGIAFVEILGIV 221
Query: 439 CAFCLCRN 462
A CL ++
Sbjct: 222 LACCLVKS 229
>sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
glycoprotein SFA-1) (CD151 antigen)
Length = 253
Score = 64.3 bits (155), Expect = 2e-10
Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 7/140 (5%)
Frame = +1
Query: 64 GIVVIVYKNSVEGRITDGLKEKIRNNYEINTDTAV--LIDSLQKNFLCCGGDSKDDWKES 237
GI+ VY + + + LK+ + Y + V +D LQ+ F CCG ++ DW++S
Sbjct: 108 GILAYVYYQQLNTELKENLKDTMVKRYHQSGHEGVSSAVDKLQQEFHCCGSNNSQDWQDS 167
Query: 238 KY--SNQTKQR-YPSSCCKTSNVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVL 402
++ S + R P SCCKT C ++ ++Y E GC V
Sbjct: 168 EWIRSGEADSRVVPDSCCKTMVAGCGKRDHASNIYKVEGGCITKLETFIQEHLRVIGAVG 227
Query: 403 LGIAFFEMFVVICAFCLCRN 462
+GIA ++F +I CL R+
Sbjct: 228 IGIACVQVFGMIFTCCLYRS 247
>sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
glycoprotein SFA-1) (CD151 antigen) (Tetraspanin-24)
(Tspan-24)
Length = 253
Score = 64.3 bits (155), Expect = 2e-10
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 7/140 (5%)
Frame = +1
Query: 64 GIVVIVYKNSVEGRITDGLKEKIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKES 237
GI+ Y + + + LK+ + Y + AV +D LQ+ F CCG ++ DW++S
Sbjct: 108 GILAYAYYQQLNTELKENLKDTMTRRYHQSGHEAVTSAVDQLQQEFHCCGSNNSQDWRDS 167
Query: 238 KYSNQTK---QRYPSSCCKTSNVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVL 402
++ + + P SCCKT C ++ ++Y E GC V
Sbjct: 168 EWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVG 227
Query: 403 LGIAFFEMFVVICAFCLCRN 462
+GIA ++F +I CL R+
Sbjct: 228 IGIACVQVFGMIFTCCLYRS 247
>sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
Length = 245
Score = 60.5 bits (145), Expect = 3e-09
Identities = 31/131 (23%), Positives = 56/131 (42%)
Frame = +1
Query: 67 IVVIVYKNSVEGRITDGLKEKIRNNYEINTDTAVLIDSLQKNFLCCGGDSKDDWKESKYS 246
IV V+++ ++ + ++ + +D +Q CCG + DWK + Y
Sbjct: 109 IVGFVFRHEIKNSFKSNYENALKEYNSTGDYRSEAVDKIQSTLHCCGVTNYGDWKGTNYY 168
Query: 247 NQTKQRYPSSCCKTSNVTCWNDENIKDVYEDGCRXXXXXXXXXXXXXXXGVLLGIAFFEM 426
++T +P SCCK C+ + V E+GC G+ G+A F++
Sbjct: 169 SET--GFPKSCCKLEG--CYPQRDADKVNEEGCFIKVMTTIESEMGVVAGISFGVACFQL 224
Query: 427 FVVICAFCLCR 459
+ A+CL R
Sbjct: 225 IGIFLAYCLSR 235
>sp|P61171|CD151_MACMU Platelet-endothelial tetraspan antigen 3 (PETA-3) (CD151 antigen)
sp|P61170|CD151_CERAE Platelet-endothelial tetraspan antigen 3 (PETA-3) (CD151 antigen)
Length = 253
Score = 58.9 bits (141), Expect = 9e-09
Identities = 38/140 (27%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Frame = +1
Query: 64 GIVVIVYKNSVEGRITDGLKEKIRNNYEINTDTAVL--IDSLQKNFLCCGGDSKDDWKES 237
G++ VY + + + LK+ + Y AV +D LQ+ F CCG ++ DW++S
Sbjct: 108 GVLAYVYYQQLNTELKENLKDTMAKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDS 167
Query: 238 KYSNQTKQR---YPSSCCKTSNVTCWNDENIKDVY--EDGCRXXXXXXXXXXXXXXXGVL 402
++ + R P SCCKT C ++ ++Y E G V
Sbjct: 168 EWIRLREARGRVVPDSCCKTVVAGCGQRDHAFNIYKVEGGFITKLETFIQEHLRVIGAVG 227
Query: 403 LGIAFFEMFVVICAFCLCRN 462
GIA ++F +I CL R+
Sbjct: 228 TGIACVQVFGMIFTCCLYRS 247
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,633,562
Number of Sequences: 369166
Number of extensions: 1232074
Number of successful extensions: 3127
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3040
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3099
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4504118060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)