Planarian EST Database

DrC_00965

Cluster detail
GO Category :
Consensus Sequence :
>DrC_00965 TTGTTGGAGGATTGGAATTTATACATGGAGCTGGTGTTAGATTTGGAAAGGTTCGAAATC CCTTGATCTTATTGGACGAATTAAGCTGTAAAGGTACTGAGTTTACCATAGAAGAATGTA ATCACGATCCTTGGCGTAAACACAACTGTAAATCTGAGGAAATTGCTGGAGTTGTTTGTA AAGAAGATAGACCATGCATGAATACAGAATTCCGTTGTCAGAAAGATAAAACATGCATAA GAATGTCTCAGATTTGTGATGGGACACGAGATTGTTCAGATGGTAGTGATGAACCTGAAG GAAGATGCTTTCTATCTGCCAAATTAGTCGATGGTCCAGATTCTAATTCTGGTCGAGTCG AAATTAAAGGAGCATATACTAAAGGAACAATTTGTGATGATGGATTTACCGACAACGAAG CTTCTGTCATTTGCAGAATGTTAGGTATTTCAGGAAGAGCCTTAGCGGTGGTTGACAGTC GATTTGGTCCAGGGAAAGGTGAAATTGTTTTATCAAACATGCGATGTAATGGAAATGAAA CTAGTTTACGGTCTTGTAAGAATTTCAAATGGGGAGAACATAAATGTTCTCATAAAGAAG ATACTGGAGTAATTTGTGGACTACCACCTCTGCAGCAAATAATTACAACTACTGTGATTT CTGTGAAAAAATCGGAACAAATACCGGGTGTATCCTGTGGTAAAAAACCAATTACACAAA GACGTGGTCGAGTTGTTGGCGGTTTTGAAACCATATACGGAGCATTTCCATGGCAAGTAG GAGTGAGACATAGAATGTCTGATTATGATGTTCATTGGTGTGGTGGCTCAATTTTGAGTG AAGATTGGATTCTTTCTGCTGCCCACTGTTATGAGAGACCGAAAAATCAATATTTTGTAA GAACAGGGGATTGGAATAACAATGAACTAGATATCTACGAACAAACGTTTGAAGTAGAGG AATTATTTATCAATCCAAAATATCAAGGTCCACCAACATATGACTATGATATGGCCATAA TAAAAATTAAAAGAATTAATGGAGTTGGGATCATGTTTAATGATCATGTTCAACCGGTAT GTTTACCAAACCCGGAAATGGTACCGGATTTGAAGACCAAATGCTTGGTTTCTGGTTGGG GTGATACTTTAAGTGAAAGAACCGAAAAGCTTTTGGCTGCTGAAGTTCCTTTGATTAAAT CAGAAAGATGTAATGAATTTTACAAAGGCAGAATAACAGACAGAATGCAATGTGCAGGCT ATGAACATGGTGGAATTGATACTTGTCAAGGTGACAGTGGGGGACCATTAGTTTGCCAAG TCAATGGAATATATACAATTTTCGGAGCTACCTCTTGGGGTGATGGTTGTGCAGTACCGA GAAGTCCCGGAGTATATGCTAGAACTGCATCTATGCTAGATTAT

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00965
         (1424 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q5G268|NETR_HYLLE  Neurotrypsin precursor                      293   6e-79
sp|Q5G266|NETR_TRAPH  Neurotrypsin precursor                      292   1e-78
sp|Q5G265|NETR_SAGLB  Neurotrypsin precursor                      292   1e-78
sp|P56730|NETR_HUMAN  Neurotrypsin precursor (Motopsin) (Ley...   292   2e-78
sp|Q5G267|NETR_MACMU  Neurotrypsin precursor                      291   2e-78
sp|Q5G269|NETR_PONPY  Neurotrypsin precursor                      291   3e-78
sp|Q5G270|NETR_GORGO  Neurotrypsin precursor                      290   5e-78
sp|Q5G271|NETR_PANTR  Neurotrypsin precursor                      290   7e-78
sp|O08762|NETR_MOUSE  Neurotrypsin precursor (Motopsin) (Bra...   286   1e-76
sp|O15393|TMPS2_HUMAN  Transmembrane protease, serine 2 prec...   202   2e-51

>sp|Q5G268|NETR_HYLLE Neurotrypsin precursor
          Length = 875

 Score =  293 bits (751), Expect = 6e-79
 Identities = 184/543 (33%), Positives = 267/543 (49%), Gaps = 82/543 (15%)
 Frame = +3

Query: 42   FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
            FG+   P ++LDE+ C G E +IE+C    W +HNC  +E AGV                
Sbjct: 335  FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393

Query: 174  -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
                             VC +    +NT   C++                        D 
Sbjct: 394  GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 453

Query: 231  TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
            +C       ++ S+   G  DCS   D         EG         +L+DG +   GRV
Sbjct: 454  SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRV 513

Query: 360  EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
            E+      GTICDDG+TD +A+VICR LG  G A A   + FG GKG I + N++C GNE
Sbjct: 514  EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             SL  C     G H C H ED GVIC                   E +  V CG + + +
Sbjct: 574  RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN--- 887
            R+ R++GG  ++ G +PWQV +R + S  D    CG ++LS  W+L+AAHC++R  N   
Sbjct: 627  RQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTR 686

Query: 888  QYFVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDH 1067
             Y VR GD++    + +E+   V+++ I+ +Y+ P + DYD+A+++++        F+ H
Sbjct: 687  NYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYR-PDSSDYDIALVRLQGPEEQCARFSSH 745

Query: 1068 VQPVCLPN-PEMVPDLKTKCLVSGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDR 1244
            V P CLP   E      + C ++GWGDT    +  L  A +PL+    C E YKGR T R
Sbjct: 746  VLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGRFTGR 805

Query: 1245 MQCAG--YEHGGIDTCQGDSGGPLVCQVNG-IYTIFGATSWGDGCAVPRSPGVYARTASM 1415
            M CAG  +EH  +D+CQGDSGGPL+C+  G  + ++G TSWG GC V  SPGVY + ++ 
Sbjct: 806  MLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGHGCGVKDSPGVYTKVSAF 865

Query: 1416 LDY 1424
            + +
Sbjct: 866  VPW 868


 Score =  109 bits (273), Expect = 2e-23
 Identities = 63/184 (34%), Positives = 79/184 (42%)
 Frame = +3

Query: 66  ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
           I    + C+G E  I  C  D W+   C  +  A V C                      
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------ 273

Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
                             G  F   +LV G   + GRVE+  A   GT+CDD + D +A 
Sbjct: 274 ------------------GPTFPIIRLVGGSSVHEGRVELYHAGQWGTVCDDQWDDADAE 315

Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
           VICR LG+SG A A   + FG G G ++L  +RC GNE S+  C    WGEH C HKED 
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375

Query: 606 GVIC 617
           GV C
Sbjct: 376 GVSC 379


 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 33/101 (32%), Positives = 49/101 (48%)
 Frame = +3

Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
           S +L  G +   G VE+  +   GT+C   + D++ASVIC  L + G+ +A      G G
Sbjct: 169 SIRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
              I  SN+RC G+E ++  C+   W    C  K    V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 269

>sp|Q5G266|NETR_TRAPH Neurotrypsin precursor
          Length = 875

 Score =  292 bits (748), Expect = 1e-78
 Identities = 182/543 (33%), Positives = 266/543 (48%), Gaps = 82/543 (15%)
 Frame = +3

Query: 42   FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIA------------------ 167
            FG+   P ++LDE+ C G E +IE+C    W +HNC  +E A                  
Sbjct: 335  FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393

Query: 168  ---------------GVVCKEDRPCMNTEFRCQK------------------------DK 230
                           G VC +    +NT   C++                        D 
Sbjct: 394  GSHEGRLEVYYRGQWGTVCDDGWTELNTYVACRQLGFKYGKQASANHFEESTGPIWLDDV 453

Query: 231  TC-------IRMSQICDGTRDCSD----------GSDEPEGRCFLSAKLVDGPDSNSGRV 359
            +C       ++ S+   G  DCS           GS+          +L+DG +   GRV
Sbjct: 454  SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGSEGHRLSLGFPVRLMDGENKKEGRV 513

Query: 360  EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
            E+      GTICDDG+TD +A+VICR LG  G A A   + FG GKG I + N++C GNE
Sbjct: 514  EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             SL  C     G H C H ED GVIC                   E +  V CG + + +
Sbjct: 574  RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN--- 887
            R+ R++GG  ++ G +PWQV +R + S  D    CG ++LS  W+L+AAHC++R  N   
Sbjct: 627  RQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTR 686

Query: 888  QYFVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDH 1067
             Y VR GD++    + +E+   V+++ I+ +Y+ P + DYD+A+++++        F+ H
Sbjct: 687  NYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYR-PDSSDYDIALVRLQGPEEQCARFSSH 745

Query: 1068 VQPVCLPN-PEMVPDLKTKCLVSGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDR 1244
            V P CLP   E      + C ++GWGDT    +  L  A +PL+    C E YKGR T R
Sbjct: 746  VLPACLPFWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGRFTGR 805

Query: 1245 MQCAG--YEHGGIDTCQGDSGGPLVCQVNG-IYTIFGATSWGDGCAVPRSPGVYARTASM 1415
            M CAG  +EH  +D+CQGDSGGPL+C+  G  + ++G TSWG GC V  SPGVY + ++ 
Sbjct: 806  MLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWAVYGVTSWGYGCGVKDSPGVYTKVSAF 865

Query: 1416 LDY 1424
            + +
Sbjct: 866  VPW 868


 Score =  110 bits (274), Expect = 1e-23
 Identities = 63/184 (34%), Positives = 79/184 (42%)
 Frame = +3

Query: 66  ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
           I    + C+G E  I  C  D W+   C  +  A V C                      
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQXGVCPQKMAAAVTCSFSH------------------ 273

Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
                             G  F   +LV G   + GRVE+  A   GT+CDD + D +A 
Sbjct: 274 ------------------GPAFPIIRLVGGNSVHEGRVELYHAGQWGTVCDDQWDDADAE 315

Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
           VICR LG+SG A A   + FG G G ++L  +RC GNE S+  C    WGEH C HKED 
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375

Query: 606 GVIC 617
           GV C
Sbjct: 376 GVSC 379


 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 33/101 (32%), Positives = 49/101 (48%)
 Frame = +3

Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
           S +L  G +   G VE+  +   GT+C   + D++ASVIC  L + G+ +A      G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
              I  SN+RC G+E ++  C+   W    C  K    V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQXGVCPQKMAAAVTC 269

>sp|Q5G265|NETR_SAGLB Neurotrypsin precursor
          Length = 875

 Score =  292 bits (748), Expect = 1e-78
 Identities = 166/461 (36%), Positives = 239/461 (51%), Gaps = 8/461 (1%)
 Frame = +3

Query: 66   ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
            I LD++SC G E    +C+   W +H+C   E  G+ C                      
Sbjct: 448  IWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVGIACYP-------------------- 487

Query: 246  SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
                        GS+          +L+DG +   GRVE+      GTICDDG+TD +A+
Sbjct: 488  ------------GSEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAA 535

Query: 426  VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
            VICR LG  G A A   + FG GKG I + N++C GNE SL  C     G H C H ED 
Sbjct: 536  VICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDA 595

Query: 606  GVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQRRGRVVGGFETIYGAFPWQVGV 785
            GVIC                   E +  V CG + + +R+ R++GG  ++ G +PWQV +
Sbjct: 596  GVIC------DYFGKKASGNSNKESLSSV-CGLRLLHRRQKRIIGGKNSLRGGWPWQVSL 648

Query: 786  RHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN---QYFVRTGDWNNNELDIYEQTFE 953
            R + S  D    CG ++LS  W+L+AAHC++R  N    Y VR GD++    + +E+   
Sbjct: 649  RLKSSHRDGRLLCGATLLSSCWVLTAAHCFKRYGNSTRNYAVRVGDYHTLVPEEFEEEIG 708

Query: 954  VEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDHVQPVCLPN-PEMVPDLKTKCLV 1130
            V+E+ I+ +Y+ P + DYD+A+++++        FN HV P CLP   E      + C +
Sbjct: 709  VQEIVIHREYR-PDSSDYDIALVRLQGPEEQCARFNSHVLPACLPLWRERPQKTASNCYI 767

Query: 1131 SGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDRMQCAG--YEHGGIDTCQGDSGG 1304
            +GWGDT    +  L  A + L+    C E YKGR T RM CAG  +EH  +D+CQGDSGG
Sbjct: 768  TGWGDTGQAYSRTLQQAAIHLLPKRFCEERYKGRFTGRMLCAGNLHEHKHVDSCQGDSGG 827

Query: 1305 PLVCQVNG-IYTIFGATSWGDGCAVPRSPGVYARTASMLDY 1424
            PL+C+  G  + ++G TSWG GC V  SPGVY + ++ + +
Sbjct: 828  PLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPW 868


 Score =  108 bits (269), Expect = 5e-23
 Identities = 62/177 (35%), Positives = 77/177 (43%)
 Frame = +3

Query: 87  CKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRMSQICDGT 266
           C+G E  I  C  D W+   C  +  A V+C                             
Sbjct: 239 CRGDEENILLCEKDIWQGGVCPQKMAAAVMCSFSH------------------------- 273

Query: 267 RDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLG 446
                      G  F   +LV G   + GRVE+  A   GTICDD + D +A VICR L 
Sbjct: 274 -----------GPAFPIIRLVGGSSVHEGRVELYHAGQWGTICDDQWDDADAEVICRQLS 322

Query: 447 ISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
           +SG A A   + FG G G ++L  +RC GNE S+  C    WGEH C HKED GV C
Sbjct: 323 LSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379


 Score =  106 bits (264), Expect = 2e-22
 Identities = 61/193 (31%), Positives = 89/193 (46%), Gaps = 1/193 (0%)
 Frame = +3

Query: 42  FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQ 221
           FG+   P ++LDE+ C G E +IE+C    W +HNC  +E AGV C              
Sbjct: 335 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------------- 379

Query: 222 KDKTCIRMSQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDD 401
                   + + DG                   +L  G  S+ GR+E+  +   GT+CDD
Sbjct: 380 --------TPLTDGV-----------------IRLAGGKGSHEGRLEVYYSGQWGTVCDD 414

Query: 402 GFTDNEASVICRMLGIS-GRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGE 578
           G+T+    V+CR LG   G+  +   + F    G I L ++ C+G ET    C   +WG 
Sbjct: 415 GWTELNTYVVCRQLGFKYGKQASA--NHFEESAGPIWLDDVSCSGKETRFLQCSRRQWGR 472

Query: 579 HKCSHKEDTGVIC 617
           H CSH+ED G+ C
Sbjct: 473 HDCSHREDVGIAC 485


 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 31/101 (30%), Positives = 48/101 (47%)
 Frame = +3

Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
           S +L    +   G VE+      GT+C   + D++ASVIC  L + G+ +A      G G
Sbjct: 169 SVRLRGSKNEFEGTVEVYANGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
              +  SN+RC G+E ++  C+   W    C  K    V+C
Sbjct: 229 LIPVYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVMC 269


 Score = 38.9 bits (89), Expect = 0.037
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = +3

Query: 42  FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVC 179
           FG+ + P I +D + C G E ++ +C      +HNC+  E AGV+C
Sbjct: 555 FGEGKGP-IHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599

>sp|P56730|NETR_HUMAN Neurotrypsin precursor (Motopsin) (Leydin)
          Length = 875

 Score =  292 bits (747), Expect = 2e-78
 Identities = 184/543 (33%), Positives = 266/543 (48%), Gaps = 82/543 (15%)
 Frame = +3

Query: 42   FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
            FG+   P ++LDE+ C G E +IE+C    W +HNC  +E AGV                
Sbjct: 335  FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393

Query: 174  -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
                             VC +    +NT   C++                        D 
Sbjct: 394  GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 453

Query: 231  TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
            +C       ++ S+   G  DCS   D         EG         +L+DG +   GRV
Sbjct: 454  SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRV 513

Query: 360  EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
            E+      GTICDDG+TD +A+VICR LG  G A A   + FG GKG I + N++C GNE
Sbjct: 514  EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             SL  C     G H C H ED GVIC                   E +  V CG + + +
Sbjct: 574  RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN--- 887
            R+ R++GG  ++ G +PWQV +R + S  D    CG ++LS  W+L+AAHC++R  N   
Sbjct: 627  RQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTR 686

Query: 888  QYFVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDH 1067
             Y VR GD++    + +E+   V+++ I+ +Y+ P   DYD+A+++++        F+ H
Sbjct: 687  SYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYR-PDRSDYDIALVRLQGPEEQCARFSSH 745

Query: 1068 VQPVCLPN-PEMVPDLKTKCLVSGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDR 1244
            V P CLP   E      + C ++GWGDT    +  L  A +PL+    C E YKGR T R
Sbjct: 746  VLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGRFTGR 805

Query: 1245 MQCAG--YEHGGIDTCQGDSGGPLVCQVNG-IYTIFGATSWGDGCAVPRSPGVYARTASM 1415
            M CAG  +EH  +D+CQGDSGGPL+C+  G  + ++G TSWG GC V  SPGVY + ++ 
Sbjct: 806  MLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAF 865

Query: 1416 LDY 1424
            + +
Sbjct: 866  VPW 868


 Score =  108 bits (269), Expect = 5e-23
 Identities = 62/184 (33%), Positives = 78/184 (42%)
 Frame = +3

Query: 66  ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
           I    + C+G E  I  C  D W+   C  +  A V C                      
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------ 273

Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
                             G  F   +L  G   + GRVE+  A   GT+CDD + D +A 
Sbjct: 274 ------------------GPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAE 315

Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
           VICR LG+SG A A   + FG G G ++L  +RC GNE S+  C    WGEH C HKED 
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375

Query: 606 GVIC 617
           GV C
Sbjct: 376 GVSC 379


 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 33/101 (32%), Positives = 49/101 (48%)
 Frame = +3

Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
           S +L  G +   G VE+  +   GT+C   + D++ASVIC  L + G+ +A      G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
              I  SN+RC G+E ++  C+   W    C  K    V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 269

>sp|Q5G267|NETR_MACMU Neurotrypsin precursor
          Length = 875

 Score =  291 bits (746), Expect = 2e-78
 Identities = 182/543 (33%), Positives = 266/543 (48%), Gaps = 82/543 (15%)
 Frame = +3

Query: 42   FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIA------------------ 167
            FG+   P ++LDE+ C G E +IE+C    W +HNC  +E A                  
Sbjct: 335  FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393

Query: 168  ---------------GVVCKEDRPCMNTEFRCQK------------------------DK 230
                           G VC +    +NT   C++                        D 
Sbjct: 394  GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 453

Query: 231  TC-------IRMSQICDGTRDCSD----------GSDEPEGRCFLSAKLVDGPDSNSGRV 359
            +C       ++ S+   G  DCS           GS+          +L+DG +   GRV
Sbjct: 454  SCSGKETRFLQCSRRQWGQHDCSHHEDVSIACYPGSEGHRLSLGFPVRLMDGENKKEGRV 513

Query: 360  EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
            E+      GTICDDG+TD +A+VICR LG  G A A   + FG GKG I + N++C GNE
Sbjct: 514  EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             SL  C     G H C H ED GVIC                   E +  V CG + + +
Sbjct: 574  RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN--- 887
            R+ R++GG  ++ G +PWQV +R + S  D    CG ++LS  W+L+AAHC++R  N   
Sbjct: 627  RQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTR 686

Query: 888  QYFVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDH 1067
             Y VR GD++    + +E+   V+++ I+ +Y+ P + DYD+A+++++        F+ H
Sbjct: 687  NYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYR-PDSSDYDIALVRLQGPEEQCARFSSH 745

Query: 1068 VQPVCLPN-PEMVPDLKTKCLVSGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDR 1244
            V P CLP   E      + C ++GWGDT    +  L  A +PL+    C E YKGR T R
Sbjct: 746  VLPACLPFWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGRFTGR 805

Query: 1245 MQCAG--YEHGGIDTCQGDSGGPLVCQVNG-IYTIFGATSWGDGCAVPRSPGVYARTASM 1415
            M CAG  +EH  +D+CQGDSGGPL+C+  G  + ++G TSWG GC V  SPGVY + ++ 
Sbjct: 806  MLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWAVYGVTSWGYGCGVKDSPGVYTKVSAF 865

Query: 1416 LDY 1424
            + +
Sbjct: 866  VPW 868


 Score =  112 bits (280), Expect = 3e-24
 Identities = 65/184 (35%), Positives = 80/184 (43%)
 Frame = +3

Query: 66  ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
           I    + C+G E  I  C  D W+   C  +  A V C   R                  
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSR------------------ 273

Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
                             G  F   +LV G   + GRVE+  A   GTICDD + D +A 
Sbjct: 274 ------------------GPAFPIIRLVGGSSVHEGRVELYHAGQWGTICDDQWDDADAE 315

Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
           VICR LG+SG A A   + FG G G ++L  +RC GNE S+  C    WGEH C HKED 
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375

Query: 606 GVIC 617
           GV C
Sbjct: 376 GVSC 379


 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 33/101 (32%), Positives = 49/101 (48%)
 Frame = +3

Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
           S +L  G +   G VE+  +   GT+C   + D++ASVIC  L + G+ +A      G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGAWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
              I  SN+RC G+E ++  C+   W    C  K    V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 269

>sp|Q5G269|NETR_PONPY Neurotrypsin precursor
          Length = 877

 Score =  291 bits (745), Expect = 3e-78
 Identities = 184/543 (33%), Positives = 266/543 (48%), Gaps = 82/543 (15%)
 Frame = +3

Query: 42   FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
            FG+   P ++LDE+ C G E +IE+C    W +HNC  +E AGV                
Sbjct: 337  FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 395

Query: 174  -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
                             VC +    +NT   C++                        D 
Sbjct: 396  GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKFGKQASANHFEESTGPIWLDDV 455

Query: 231  TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
            +C       ++ S+   G  DCS   D         EG         +L+DG +   GRV
Sbjct: 456  SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRV 515

Query: 360  EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
            E+      GTICDDG+TD +A+VICR LG  G A A   + FG GKG I + N+RC GNE
Sbjct: 516  EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVRCTGNE 575

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             SL  C     G H C H ED GVIC                   E +  V CG + + +
Sbjct: 576  RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 628

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN--- 887
            R+ R++GG  ++ G +PWQV +R + S  D    CG ++LS  W+L+AAHC++R  N   
Sbjct: 629  RQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTR 688

Query: 888  QYFVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDH 1067
             Y VR GD++    + +E+   V+++ I+ +Y+ P + DYD+A+++++        F+ H
Sbjct: 689  NYAVRVGDYHTLVPEEFEEEVGVQQIVIHREYR-PDSSDYDIALVRLQGPEEQCARFSSH 747

Query: 1068 VQPVCLPN-PEMVPDLKTKCLVSGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDR 1244
            V P CLP   E      + C ++GWGDT    +  L  A +PL+    C E YKG  T R
Sbjct: 748  VLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGXFTGR 807

Query: 1245 MQCAG--YEHGGIDTCQGDSGGPLVCQVNG-IYTIFGATSWGDGCAVPRSPGVYARTASM 1415
            M CAG  +EH  +D+CQGDSGGPL+C+  G  + ++G TSWG GC V  SPGVY + ++ 
Sbjct: 808  MLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAF 867

Query: 1416 LDY 1424
            + +
Sbjct: 868  VPW 870


 Score =  107 bits (266), Expect = 1e-22
 Identities = 62/184 (33%), Positives = 78/184 (42%)
 Frame = +3

Query: 66  ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
           I    + C+G E  I  C  D W+   C  +  A V C                      
Sbjct: 234 IYWSNVRCQGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------ 275

Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
                             G  F   +LV G   + GRVE+  A   GT+CDD + D +A 
Sbjct: 276 ------------------GPTFPIIRLVGGSSVHEGRVELYHAGQWGTVCDDQWDDADAE 317

Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
           VICR L +SG A A   + FG G G ++L  +RC GNE S+  C    WGEH C HKED 
Sbjct: 318 VICRQLSLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 377

Query: 606 GVIC 617
           GV C
Sbjct: 378 GVSC 381


 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 33/101 (32%), Positives = 49/101 (48%)
 Frame = +3

Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
           S +L  G +   G VE+  +   GT+C   + D++ASVIC  L + G+ +A      G G
Sbjct: 171 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 230

Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
              I  SN+RC G+E ++  C+   W    C  K    V C
Sbjct: 231 LIPIYWSNVRCQGDEENILLCEKDIWQGGVCPQKMAAAVTC 271

>sp|Q5G270|NETR_GORGO Neurotrypsin precursor
          Length = 876

 Score =  290 bits (743), Expect = 5e-78
 Identities = 183/543 (33%), Positives = 266/543 (48%), Gaps = 82/543 (15%)
 Frame = +3

Query: 42   FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
            FG+   P ++LDE+ C G E +IE+C    W +HNC  +E AGV                
Sbjct: 336  FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 394

Query: 174  -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
                             VC +    +NT   C++                        D 
Sbjct: 395  GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 454

Query: 231  TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
            +C       ++ S+   G  DCS   D         EG         +L+DG +   GRV
Sbjct: 455  SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRV 514

Query: 360  EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
            E+      GTICDDG+TD +A+VICR LG  G A A   + FG GKG I + N++C GNE
Sbjct: 515  EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 574

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             SL  C     G H C H ED GVIC                   E +  V CG + + +
Sbjct: 575  RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 627

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN--- 887
            R+ R++GG  ++ G +PWQV +R +    D    CG ++LS  W+L+AAHC++R  N   
Sbjct: 628  RQKRIIGGKNSLRGGWPWQVSLRLKSYHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTR 687

Query: 888  QYFVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDH 1067
             Y VR GD++    + +E+   V+++ I+ +Y+ P + DYD+A+++++        F+ H
Sbjct: 688  NYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYR-PDSSDYDIALVRLQGPEEQCARFSSH 746

Query: 1068 VQPVCLPN-PEMVPDLKTKCLVSGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDR 1244
            V P CLP   E      + C ++GWGDT    +  L  A +PL+    C E YKGR T R
Sbjct: 747  VLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGRFTGR 806

Query: 1245 MQCAG--YEHGGIDTCQGDSGGPLVCQVNG-IYTIFGATSWGDGCAVPRSPGVYARTASM 1415
            M CAG  +EH  +D+CQGDSGGPL+C+  G  + ++G TSWG GC V  SPGVY + ++ 
Sbjct: 807  MLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAF 866

Query: 1416 LDY 1424
            + +
Sbjct: 867  VPW 869


 Score =  107 bits (268), Expect = 7e-23
 Identities = 61/177 (34%), Positives = 76/177 (42%)
 Frame = +3

Query: 87  CKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRMSQICDGT 266
           C+G E  I  C  D W+   C  +  A V C                             
Sbjct: 240 CRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------------- 274

Query: 267 RDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLG 446
                      G  F   +L  G   + GRVE+  A   GT+CDD + D +A VICR LG
Sbjct: 275 -----------GPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLG 323

Query: 447 ISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
           +SG A A   + FG G G ++L  +RC GNE S+  C    WGEH C HKED GV C
Sbjct: 324 LSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 380


 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 32/101 (31%), Positives = 49/101 (48%)
 Frame = +3

Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
           S +L  G +   G VE+  +   GT+C   + D++ASVIC  L + G+ +A      G G
Sbjct: 170 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 229

Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
              +  SN+RC G+E ++  C+   W    C  K    V C
Sbjct: 230 LIPVYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 270

>sp|Q5G271|NETR_PANTR Neurotrypsin precursor
          Length = 875

 Score =  290 bits (742), Expect = 7e-78
 Identities = 184/543 (33%), Positives = 265/543 (48%), Gaps = 82/543 (15%)
 Frame = +3

Query: 42   FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
            FG+   P ++LDE+ C G E +IE+C    W +HNC  +E AGV                
Sbjct: 335  FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393

Query: 174  -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
                             VC +    +NT   C++                        D 
Sbjct: 394  GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 453

Query: 231  TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
            +C       ++ S+   G  DCS   D         EG         +LVDG +   GRV
Sbjct: 454  SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLVDGENKKEGRV 513

Query: 360  EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
            E+      GTICDDG+TD +A+VICR LG  G A A   + FG GKG I + N++C GNE
Sbjct: 514  EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             SL  C     G H C H ED GVIC                   E +  V CG + + +
Sbjct: 574  RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN--- 887
            R+ R++GG  ++ G +PWQV +R + S  D    CG ++LS  W+L+AAHC++R  N   
Sbjct: 627  RQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTR 686

Query: 888  QYFVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDH 1067
             Y VR GD++    + +E+   V+++ I+ +Y+ P   DYD+A+++++        F+ H
Sbjct: 687  SYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYR-PDRSDYDIALVRLQGPEEQCARFSSH 745

Query: 1068 VQPVCLPN-PEMVPDLKTKCLVSGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDR 1244
            V P CLP   E      + C ++GWGDT    +  L  A +PL+    C E YK R T R
Sbjct: 746  VLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKRRFTGR 805

Query: 1245 MQCAG--YEHGGIDTCQGDSGGPLVCQVNG-IYTIFGATSWGDGCAVPRSPGVYARTASM 1415
            M CAG  +EH  +D+CQGDSGGPL+C+  G  + ++G TSWG GC V  SPGVY + ++ 
Sbjct: 806  MLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAF 865

Query: 1416 LDY 1424
            + +
Sbjct: 866  VPW 868


 Score =  108 bits (269), Expect = 5e-23
 Identities = 62/184 (33%), Positives = 78/184 (42%)
 Frame = +3

Query: 66  ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
           I    + C+G E  I  C  D W+   C  +  A V C                      
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------ 273

Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
                             G  F   +L  G   + GRVE+  A   GT+CDD + D +A 
Sbjct: 274 ------------------GPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAE 315

Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
           VICR LG+SG A A   + FG G G ++L  +RC GNE S+  C    WGEH C HKED 
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375

Query: 606 GVIC 617
           GV C
Sbjct: 376 GVSC 379


 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 33/101 (32%), Positives = 49/101 (48%)
 Frame = +3

Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
           S +L  G +   G VE+  +   GT+C   + D++ASVIC  L + G+ +A      G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
              I  SN+RC G+E ++  C+   W    C  K    V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 269

>sp|O08762|NETR_MOUSE Neurotrypsin precursor (Motopsin) (Brain-specific serine protease 3)
            (BSSP-3)
          Length = 761

 Score =  286 bits (732), Expect = 1e-76
 Identities = 183/543 (33%), Positives = 261/543 (48%), Gaps = 82/543 (15%)
 Frame = +3

Query: 42   FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
            FG+   P ILLDE+ C G E +IE+C    W +HNC  +E AGV                
Sbjct: 221  FGEGSGP-ILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCVPLTDGVIRLAGGK 279

Query: 174  -----------------VCKEDRPCMNTEFRCQ--------------------------- 221
                             VC +    MNT   C+                           
Sbjct: 280  STHEGRLEVYYKGQWGTVCDDGWTEMNTYVACRLLGFKYGKQSSVNHFDGSNRPIWLDDV 339

Query: 222  ----KDKTCIRMSQICDGTRDCSDGSD-------EPEGRCF---LSAKLVDGPDSNSGRV 359
                K+ + I+ S+   G  DCS   D       + +G         +LVDG +   GRV
Sbjct: 340  SCSGKEVSFIQCSRRQWGRHDCSHREDVGLTCYPDSDGHRLSPGFPIRLVDGENKKEGRV 399

Query: 360  EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
            E+      GTICDDG+TD  A+VICR LG  G A A   + FG GKG I + N++C GNE
Sbjct: 400  EVFVNGQWGTICDDGWTDKHAAVICRQLGYKGPARARTMAYFGEGKGPIHMDNVKCTGNE 459

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             +L  C     G H C H ED GVIC              S   ++++    CG + + +
Sbjct: 460  KALADCVKQDIGRHNCRHSEDAGVICD-------YLEKKASSSGNKEMLSSGCGLRLLHR 512

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVH-WCGGSILSEDWILSAAHCYERPKN--- 887
            R+ R++GG  ++ GA+PWQ  +R R +  D    CG ++LS  W+L+AAHC++R  N   
Sbjct: 513  RQKRIIGGNNSLRGAWPWQASLRLRSAHGDGRLLCGATLLSSCWVLTAAHCFKRYGNNSR 572

Query: 888  QYFVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDH 1067
             Y VR GD++    + +EQ   V+++ I+  Y+ P   DYD+A+++++         + H
Sbjct: 573  SYAVRVGDYHTLVPEEFEQEIGVQQIVIHRNYR-PDRSDYDIALVRLQGPGEQCARLSTH 631

Query: 1068 VQPVCLPN-PEMVPDLKTKCLVSGWGDTLSERTEKLLAAEVPLIKSERCNEFYKGRITDR 1244
            V P CLP   E      + C ++GWGDT    +  L  A VPL+    C E YKG  T R
Sbjct: 632  VLPACLPLWRERPQKTASNCHITGWGDTGRAYSRTLQQAAVPLLPKRFCKERYKGLFTGR 691

Query: 1245 MQCAG--YEHGGIDTCQGDSGGPLVCQ-VNGIYTIFGATSWGDGCAVPRSPGVYARTASM 1415
            M CAG   E   +D+CQGDSGGPL+C+  +  + ++G TSWG GC V  +PGVY R  + 
Sbjct: 692  MLCAGNLQEDNRVDSCQGDSGGPLMCEKPDESWVVYGVTSWGYGCGVKDTPGVYTRVPAF 751

Query: 1416 LDY 1424
            + +
Sbjct: 752  VPW 754


 Score =  107 bits (267), Expect = 8e-23
 Identities = 56/119 (47%), Positives = 66/119 (55%)
 Frame = +3

Query: 261 GTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRM 440
           G  DC  G   P  R      LV G   + GRVE+  A   GTICDD + + +A VICR 
Sbjct: 153 GYCDCGQGPALPVIR------LVGGNSGHEGRVELYHAGQWGTICDDQWDNADADVICRQ 206

Query: 441 LGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
           LG+SG A A   + FG G G I+L  +RC GNE S+  C    WGEH C HKED GV C
Sbjct: 207 LGLSGIAKAWHQAHFGEGSGPILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 265

>sp|O15393|TMPS2_HUMAN Transmembrane protease, serine 2 precursor [Contains: Transmembrane
            protease, serine 2 non-catalytic chain; Transmembrane
            protease, serine 2 catalytic chain]
          Length = 492

 Score =  202 bits (514), Expect = 2e-51
 Identities = 135/421 (32%), Positives = 201/421 (47%), Gaps = 11/421 (2%)
 Frame = +3

Query: 195  CMNTEFRCQKDKTCIRMSQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGA 374
            C N+   C    TCI  S  CDG   C  G DE   RC      + GP+     +++  +
Sbjct: 113  CSNSGIECDSSGTCINPSNWCDGVSHCPGGEDE--NRCVR----LYGPNFI---LQMYSS 163

Query: 375  YTKG--TICDDGFTDNEASVICRMLGISGR---ALAVVDSRFGPGKGEIVLSNMRCNGNE 539
              K    +C D + +N     CR +G       +  +VD            S M+ N + 
Sbjct: 164  QRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGST-------SFMKLNTSA 216

Query: 540  TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
             ++   K   +    CS K    + C                        ++CG    + 
Sbjct: 217  GNVDIYKKL-YHSDACSSKAVVSLRC------------------------IACGVNLNSS 251

Query: 720  RRGRVVGGFETIYGAFPWQVGVRHRMSDYDVHWCGGSILSEDWILSAAHCYERPKNQ--Y 893
            R+ R+VGG   + GA+PWQV +  +    +VH CGGSI++ +WI++AAHC E+P N   +
Sbjct: 252  RQSRIVGGESALPGAWPWQVSLHVQ----NVHVCGGSIITPEWIVTAAHCVEKPLNNPWH 307

Query: 894  FVRTGDWNNNELDIYEQTFEVEELFINPKYQGPPTYDYDMAIIKIKRINGVGIMFNDHVQ 1073
            +             Y   ++VE++  +P Y    T + D+A++K+++     + FND V+
Sbjct: 308  WTAFAGILRQSFMFYGAGYQVEKVISHPNYDSK-TKNNDIALMKLQK----PLTFNDLVK 362

Query: 1074 PVCLPNPEMVPDLKTKCLVSGWGDT--LSERTEKLLAAEVPLIKSERCNE--FYKGRITD 1241
            PVCLPNP M+   +  C +SGWG T    + +E L AA+V LI+++RCN    Y   IT 
Sbjct: 363  PVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITP 422

Query: 1242 RMQCAGYEHGGIDTCQGDSGGPLVCQVNGIYTIFGATSWGDGCAVPRSPGVYARTASMLD 1421
             M CAG+  G +D+CQGDSGGPLV   N I+ + G TSWG GCA    PGVY       D
Sbjct: 423  AMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTD 482

Query: 1422 Y 1424
            +
Sbjct: 483  W 483

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 184,520,362
Number of Sequences: 369166
Number of extensions: 4361364
Number of successful extensions: 15348
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 12127
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13827
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 17026268400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00965

Planaria EST Database

DrC_00965

BLASTX 2.2.13 [Nov-27-2005]

Cluster detail