Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_F12
(801 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O08762|NETR_MOUSE Neurotrypsin precursor (Motopsin) (Bra... 144 4e-34
sp|Q5G269|NETR_PONPY Neurotrypsin precursor 139 7e-33
sp|Q5G271|NETR_PANTR Neurotrypsin precursor 139 7e-33
sp|P56730|NETR_HUMAN Neurotrypsin precursor (Motopsin) (Ley... 138 2e-32
sp|Q5G268|NETR_HYLLE Neurotrypsin precursor 138 2e-32
sp|Q5G266|NETR_TRAPH Neurotrypsin precursor 138 2e-32
sp|Q5G265|NETR_SAGLB Neurotrypsin precursor 137 3e-32
sp|Q5G270|NETR_GORGO Neurotrypsin precursor 137 3e-32
sp|Q5G267|NETR_MACMU Neurotrypsin precursor 137 3e-32
sp|P30205|WC11_BOVIN Antigen WC1.1 precursor 104 3e-22
>sp|O08762|NETR_MOUSE Neurotrypsin precursor (Motopsin) (Brain-specific serine protease 3)
(BSSP-3)
Length = 761
Score = 144 bits (362), Expect = 4e-34
Identities = 101/325 (31%), Positives = 139/325 (42%), Gaps = 74/325 (22%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
FG+ P ILLDE+ C G E +IE+C W +HNC +E AGV
Sbjct: 221 FGEGSGP-ILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCVPLTDGVIRLAGGK 279
Query: 174 -----------------VCKEDRPCMNTEFRCQ--------------------------- 221
VC + MNT C+
Sbjct: 280 STHEGRLEVYYKGQWGTVCDDGWTEMNTYVACRLLGFKYGKQSSVNHFDGSNRPIWLDDV 339
Query: 222 ----KDKTCIRMSQICDGTRDCSDGSD-------EPEGRCF---LSAKLVDGPDSNSGRV 359
K+ + I+ S+ G DCS D + +G +LVDG + GRV
Sbjct: 340 SCSGKEVSFIQCSRRQWGRHDCSHREDVGLTCYPDSDGHRLSPGFPIRLVDGENKKEGRV 399
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
E+ GTICDDG+TD A+VICR LG G A A + FG GKG I + N++C GNE
Sbjct: 400 EVFVNGQWGTICDDGWTDKHAAVICRQLGYKGPARARTMAYFGEGKGPIHMDNVKCTGNE 459
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
+L C G H C H ED GVIC S ++++ CG + + +
Sbjct: 460 KALADCVKQDIGRHNCRHSEDAGVICD-------YLEKKASSSGNKEMLSSGCGLRLLHR 512
Query: 720 RRGRVVGGFETIYGAFPWQVGVRHR 794
R+ R++GG ++ GA+PWQ +R R
Sbjct: 513 RQKRIIGGNNSLRGAWPWQASLRLR 537
Score = 107 bits (267), Expect = 4e-23
Identities = 56/119 (47%), Positives = 66/119 (55%)
Frame = +3
Query: 261 GTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRM 440
G DC G P R LV G + GRVE+ A GTICDD + + +A VICR
Sbjct: 153 GYCDCGQGPALPVIR------LVGGNSGHEGRVELYHAGQWGTICDDQWDNADADVICRQ 206
Query: 441 LGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
LG+SG A A + FG G G I+L +RC GNE S+ C WGEH C HKED GV C
Sbjct: 207 LGLSGIAKAWHQAHFGEGSGPILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 265
>sp|Q5G269|NETR_PONPY Neurotrypsin precursor
Length = 877
Score = 139 bits (351), Expect = 7e-33
Identities = 101/327 (30%), Positives = 139/327 (42%), Gaps = 74/327 (22%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
FG+ P ++LDE+ C G E +IE+C W +HNC +E AGV
Sbjct: 337 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 395
Query: 174 -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
VC + +NT C++ D
Sbjct: 396 GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKFGKQASANHFEESTGPIWLDDV 455
Query: 231 TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
+C ++ S+ G DCS D EG +L+DG + GRV
Sbjct: 456 SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRV 515
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
E+ GTICDDG+TD +A+VICR LG G A A + FG GKG I + N+RC GNE
Sbjct: 516 EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVRCTGNE 575
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
SL C G H C H ED GVIC E + V CG + + +
Sbjct: 576 RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 628
Query: 720 RRGRVVGGFETIYGAFPWQVGVRHRMS 800
R+ R++GG ++ G +PWQV +R + S
Sbjct: 629 RQKRIIGGKNSLRGGWPWQVSLRLKSS 655
Score = 107 bits (266), Expect = 5e-23
Identities = 62/184 (33%), Positives = 78/184 (42%)
Frame = +3
Query: 66 ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
I + C+G E I C D W+ C + A V C
Sbjct: 234 IYWSNVRCQGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------ 275
Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
G F +LV G + GRVE+ A GT+CDD + D +A
Sbjct: 276 ------------------GPTFPIIRLVGGSSVHEGRVELYHAGQWGTVCDDQWDDADAE 317
Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
VICR L +SG A A + FG G G ++L +RC GNE S+ C WGEH C HKED
Sbjct: 318 VICRQLSLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 377
Query: 606 GVIC 617
GV C
Sbjct: 378 GVSC 381
Score = 61.2 bits (147), Expect = 3e-09
Identities = 33/101 (32%), Positives = 49/101 (48%)
Frame = +3
Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
S +L G + G VE+ + GT+C + D++ASVIC L + G+ +A G G
Sbjct: 171 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 230
Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
I SN+RC G+E ++ C+ W C K V C
Sbjct: 231 LIPIYWSNVRCQGDEENILLCEKDIWQGGVCPQKMAAAVTC 271
>sp|Q5G271|NETR_PANTR Neurotrypsin precursor
Length = 875
Score = 139 bits (351), Expect = 7e-33
Identities = 101/327 (30%), Positives = 139/327 (42%), Gaps = 74/327 (22%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
FG+ P ++LDE+ C G E +IE+C W +HNC +E AGV
Sbjct: 335 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393
Query: 174 -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
VC + +NT C++ D
Sbjct: 394 GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 453
Query: 231 TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
+C ++ S+ G DCS D EG +LVDG + GRV
Sbjct: 454 SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLVDGENKKEGRV 513
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
E+ GTICDDG+TD +A+VICR LG G A A + FG GKG I + N++C GNE
Sbjct: 514 EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
SL C G H C H ED GVIC E + V CG + + +
Sbjct: 574 RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626
Query: 720 RRGRVVGGFETIYGAFPWQVGVRHRMS 800
R+ R++GG ++ G +PWQV +R + S
Sbjct: 627 RQKRIIGGKNSLRGGWPWQVSLRLKSS 653
Score = 108 bits (269), Expect = 2e-23
Identities = 62/184 (33%), Positives = 78/184 (42%)
Frame = +3
Query: 66 ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
I + C+G E I C D W+ C + A V C
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------ 273
Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
G F +L G + GRVE+ A GT+CDD + D +A
Sbjct: 274 ------------------GPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAE 315
Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
VICR LG+SG A A + FG G G ++L +RC GNE S+ C WGEH C HKED
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375
Query: 606 GVIC 617
GV C
Sbjct: 376 GVSC 379
Score = 61.2 bits (147), Expect = 3e-09
Identities = 33/101 (32%), Positives = 49/101 (48%)
Frame = +3
Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
S +L G + G VE+ + GT+C + D++ASVIC L + G+ +A G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
I SN+RC G+E ++ C+ W C K V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 269
>sp|P56730|NETR_HUMAN Neurotrypsin precursor (Motopsin) (Leydin)
Length = 875
Score = 138 bits (348), Expect = 2e-32
Identities = 100/327 (30%), Positives = 139/327 (42%), Gaps = 74/327 (22%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
FG+ P ++LDE+ C G E +IE+C W +HNC +E AGV
Sbjct: 335 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393
Query: 174 -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
VC + +NT C++ D
Sbjct: 394 GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 453
Query: 231 TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
+C ++ S+ G DCS D EG +L+DG + GRV
Sbjct: 454 SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRV 513
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
E+ GTICDDG+TD +A+VICR LG G A A + FG GKG I + N++C GNE
Sbjct: 514 EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
SL C G H C H ED GVIC E + V CG + + +
Sbjct: 574 RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626
Query: 720 RRGRVVGGFETIYGAFPWQVGVRHRMS 800
R+ R++GG ++ G +PWQV +R + S
Sbjct: 627 RQKRIIGGKNSLRGGWPWQVSLRLKSS 653
Score = 108 bits (269), Expect = 2e-23
Identities = 62/184 (33%), Positives = 78/184 (42%)
Frame = +3
Query: 66 ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
I + C+G E I C D W+ C + A V C
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------ 273
Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
G F +L G + GRVE+ A GT+CDD + D +A
Sbjct: 274 ------------------GPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAE 315
Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
VICR LG+SG A A + FG G G ++L +RC GNE S+ C WGEH C HKED
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375
Query: 606 GVIC 617
GV C
Sbjct: 376 GVSC 379
Score = 61.2 bits (147), Expect = 3e-09
Identities = 33/101 (32%), Positives = 49/101 (48%)
Frame = +3
Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
S +L G + G VE+ + GT+C + D++ASVIC L + G+ +A G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
I SN+RC G+E ++ C+ W C K V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 269
>sp|Q5G268|NETR_HYLLE Neurotrypsin precursor
Length = 875
Score = 138 bits (348), Expect = 2e-32
Identities = 100/327 (30%), Positives = 139/327 (42%), Gaps = 74/327 (22%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
FG+ P ++LDE+ C G E +IE+C W +HNC +E AGV
Sbjct: 335 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393
Query: 174 -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
VC + +NT C++ D
Sbjct: 394 GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 453
Query: 231 TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
+C ++ S+ G DCS D EG +L+DG + GRV
Sbjct: 454 SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRV 513
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
E+ GTICDDG+TD +A+VICR LG G A A + FG GKG I + N++C GNE
Sbjct: 514 EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
SL C G H C H ED GVIC E + V CG + + +
Sbjct: 574 RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626
Query: 720 RRGRVVGGFETIYGAFPWQVGVRHRMS 800
R+ R++GG ++ G +PWQV +R + S
Sbjct: 627 RQKRIIGGKNSLRGGWPWQVSLRLKSS 653
Score = 109 bits (273), Expect = 8e-24
Identities = 63/184 (34%), Positives = 79/184 (42%)
Frame = +3
Query: 66 ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
I + C+G E I C D W+ C + A V C
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------ 273
Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
G F +LV G + GRVE+ A GT+CDD + D +A
Sbjct: 274 ------------------GPTFPIIRLVGGSSVHEGRVELYHAGQWGTVCDDQWDDADAE 315
Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
VICR LG+SG A A + FG G G ++L +RC GNE S+ C WGEH C HKED
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375
Query: 606 GVIC 617
GV C
Sbjct: 376 GVSC 379
Score = 60.8 bits (146), Expect = 4e-09
Identities = 33/101 (32%), Positives = 49/101 (48%)
Frame = +3
Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
S +L G + G VE+ + GT+C + D++ASVIC L + G+ +A G G
Sbjct: 169 SIRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
I SN+RC G+E ++ C+ W C K V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 269
>sp|Q5G266|NETR_TRAPH Neurotrypsin precursor
Length = 875
Score = 138 bits (347), Expect = 2e-32
Identities = 98/327 (29%), Positives = 138/327 (42%), Gaps = 74/327 (22%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIA------------------ 167
FG+ P ++LDE+ C G E +IE+C W +HNC +E A
Sbjct: 335 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393
Query: 168 ---------------GVVCKEDRPCMNTEFRCQK------------------------DK 230
G VC + +NT C++ D
Sbjct: 394 GSHEGRLEVYYRGQWGTVCDDGWTELNTYVACRQLGFKYGKQASANHFEESTGPIWLDDV 453
Query: 231 TC-------IRMSQICDGTRDCSD----------GSDEPEGRCFLSAKLVDGPDSNSGRV 359
+C ++ S+ G DCS GS+ +L+DG + GRV
Sbjct: 454 SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGSEGHRLSLGFPVRLMDGENKKEGRV 513
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
E+ GTICDDG+TD +A+VICR LG G A A + FG GKG I + N++C GNE
Sbjct: 514 EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
SL C G H C H ED GVIC E + V CG + + +
Sbjct: 574 RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626
Query: 720 RRGRVVGGFETIYGAFPWQVGVRHRMS 800
R+ R++GG ++ G +PWQV +R + S
Sbjct: 627 RQKRIIGGKNSLRGGWPWQVSLRLKSS 653
Score = 110 bits (274), Expect = 6e-24
Identities = 63/184 (34%), Positives = 79/184 (42%)
Frame = +3
Query: 66 ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
I + C+G E I C D W+ C + A V C
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQXGVCPQKMAAAVTCSFSH------------------ 273
Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
G F +LV G + GRVE+ A GT+CDD + D +A
Sbjct: 274 ------------------GPAFPIIRLVGGNSVHEGRVELYHAGQWGTVCDDQWDDADAE 315
Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
VICR LG+SG A A + FG G G ++L +RC GNE S+ C WGEH C HKED
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375
Query: 606 GVIC 617
GV C
Sbjct: 376 GVSC 379
Score = 61.6 bits (148), Expect = 2e-09
Identities = 33/101 (32%), Positives = 49/101 (48%)
Frame = +3
Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
S +L G + G VE+ + GT+C + D++ASVIC L + G+ +A G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
I SN+RC G+E ++ C+ W C K V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQXGVCPQKMAAAVTC 269
>sp|Q5G265|NETR_SAGLB Neurotrypsin precursor
Length = 875
Score = 137 bits (346), Expect = 3e-32
Identities = 81/245 (33%), Positives = 112/245 (45%)
Frame = +3
Query: 66 ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
I LD++SC G E +C+ W +H+C E G+ C
Sbjct: 448 IWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVGIACYP-------------------- 487
Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
GS+ +L+DG + GRVE+ GTICDDG+TD +A+
Sbjct: 488 ------------GSEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAA 535
Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
VICR LG G A A + FG GKG I + N++C GNE SL C G H C H ED
Sbjct: 536 VICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDA 595
Query: 606 GVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQRRGRVVGGFETIYGAFPWQVGV 785
GVIC E + V CG + + +R+ R++GG ++ G +PWQV +
Sbjct: 596 GVIC------DYFGKKASGNSNKESLSSV-CGLRLLHRRQKRIIGGKNSLRGGWPWQVSL 648
Query: 786 RHRMS 800
R + S
Sbjct: 649 RLKSS 653
Score = 108 bits (269), Expect = 2e-23
Identities = 62/177 (35%), Positives = 77/177 (43%)
Frame = +3
Query: 87 CKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRMSQICDGT 266
C+G E I C D W+ C + A V+C
Sbjct: 239 CRGDEENILLCEKDIWQGGVCPQKMAAAVMCSFSH------------------------- 273
Query: 267 RDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLG 446
G F +LV G + GRVE+ A GTICDD + D +A VICR L
Sbjct: 274 -----------GPAFPIIRLVGGSSVHEGRVELYHAGQWGTICDDQWDDADAEVICRQLS 322
Query: 447 ISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
+SG A A + FG G G ++L +RC GNE S+ C WGEH C HKED GV C
Sbjct: 323 LSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379
Score = 106 bits (264), Expect = 8e-23
Identities = 61/193 (31%), Positives = 89/193 (46%), Gaps = 1/193 (0%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQ 221
FG+ P ++LDE+ C G E +IE+C W +HNC +E AGV C
Sbjct: 335 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------------- 379
Query: 222 KDKTCIRMSQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDD 401
+ + DG +L G S+ GR+E+ + GT+CDD
Sbjct: 380 --------TPLTDGV-----------------IRLAGGKGSHEGRLEVYYSGQWGTVCDD 414
Query: 402 GFTDNEASVICRMLGIS-GRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGE 578
G+T+ V+CR LG G+ + + F G I L ++ C+G ET C +WG
Sbjct: 415 GWTELNTYVVCRQLGFKYGKQASA--NHFEESAGPIWLDDVSCSGKETRFLQCSRRQWGR 472
Query: 579 HKCSHKEDTGVIC 617
H CSH+ED G+ C
Sbjct: 473 HDCSHREDVGIAC 485
Score = 58.2 bits (139), Expect = 3e-08
Identities = 31/101 (30%), Positives = 48/101 (47%)
Frame = +3
Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
S +L + G VE+ GT+C + D++ASVIC L + G+ +A G G
Sbjct: 169 SVRLRGSKNEFEGTVEVYANGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
+ SN+RC G+E ++ C+ W C K V+C
Sbjct: 229 LIPVYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVMC 269
Score = 38.9 bits (89), Expect = 0.017
Identities = 17/46 (36%), Positives = 27/46 (58%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVC 179
FG+ + P I +D + C G E ++ +C +HNC+ E AGV+C
Sbjct: 555 FGEGKGP-IHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
>sp|Q5G270|NETR_GORGO Neurotrypsin precursor
Length = 876
Score = 137 bits (346), Expect = 3e-32
Identities = 99/323 (30%), Positives = 137/323 (42%), Gaps = 74/323 (22%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGV---------------- 173
FG+ P ++LDE+ C G E +IE+C W +HNC +E AGV
Sbjct: 336 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 394
Query: 174 -----------------VCKEDRPCMNTEFRCQK------------------------DK 230
VC + +NT C++ D
Sbjct: 395 GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 454
Query: 231 TC-------IRMSQICDGTRDCSDGSDEP-------EGRCF---LSAKLVDGPDSNSGRV 359
+C ++ S+ G DCS D EG +L+DG + GRV
Sbjct: 455 SCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRV 514
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
E+ GTICDDG+TD +A+VICR LG G A A + FG GKG I + N++C GNE
Sbjct: 515 EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 574
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
SL C G H C H ED GVIC E + V CG + + +
Sbjct: 575 RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 627
Query: 720 RRGRVVGGFETIYGAFPWQVGVR 788
R+ R++GG ++ G +PWQV +R
Sbjct: 628 RQKRIIGGKNSLRGGWPWQVSLR 650
Score = 107 bits (268), Expect = 3e-23
Identities = 61/177 (34%), Positives = 76/177 (42%)
Frame = +3
Query: 87 CKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRMSQICDGT 266
C+G E I C D W+ C + A V C
Sbjct: 240 CRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH------------------------- 274
Query: 267 RDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLG 446
G F +L G + GRVE+ A GT+CDD + D +A VICR LG
Sbjct: 275 -----------GPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLG 323
Query: 447 ISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
+SG A A + FG G G ++L +RC GNE S+ C WGEH C HKED GV C
Sbjct: 324 LSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 380
Score = 60.8 bits (146), Expect = 4e-09
Identities = 32/101 (31%), Positives = 49/101 (48%)
Frame = +3
Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
S +L G + G VE+ + GT+C + D++ASVIC L + G+ +A G G
Sbjct: 170 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 229
Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
+ SN+RC G+E ++ C+ W C K V C
Sbjct: 230 LIPVYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 270
>sp|Q5G267|NETR_MACMU Neurotrypsin precursor
Length = 875
Score = 137 bits (345), Expect = 3e-32
Identities = 98/327 (29%), Positives = 138/327 (42%), Gaps = 74/327 (22%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIA------------------ 167
FG+ P ++LDE+ C G E +IE+C W +HNC +E A
Sbjct: 335 FGEGSGP-VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGK 393
Query: 168 ---------------GVVCKEDRPCMNTEFRCQK------------------------DK 230
G VC + +NT C++ D
Sbjct: 394 GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLDDV 453
Query: 231 TC-------IRMSQICDGTRDCSD----------GSDEPEGRCFLSAKLVDGPDSNSGRV 359
+C ++ S+ G DCS GS+ +L+DG + GRV
Sbjct: 454 SCSGKETRFLQCSRRQWGQHDCSHHEDVSIACYPGSEGHRLSLGFPVRLMDGENKKEGRV 513
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
E+ GTICDDG+TD +A+VICR LG G A A + FG GKG I + N++C GNE
Sbjct: 514 EVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNE 573
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVICGLPPLQQIITTTVISVKKSEQIPGVSCGKKPITQ 719
SL C G H C H ED GVIC E + V CG + + +
Sbjct: 574 RSLADCIKQDIGRHNCRHSEDAGVIC------DYFGKKASGNSNKESLSSV-CGLRLLHR 626
Query: 720 RRGRVVGGFETIYGAFPWQVGVRHRMS 800
R+ R++GG ++ G +PWQV +R + S
Sbjct: 627 RQKRIIGGKNSLRGGWPWQVSLRLKSS 653
Score = 112 bits (280), Expect = 1e-24
Identities = 65/184 (35%), Positives = 80/184 (43%)
Frame = +3
Query: 66 ILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRM 245
I + C+G E I C D W+ C + A V C R
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSR------------------ 273
Query: 246 SQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEAS 425
G F +LV G + GRVE+ A GTICDD + D +A
Sbjct: 274 ------------------GPAFPIIRLVGGSSVHEGRVELYHAGQWGTICDDQWDDADAE 315
Query: 426 VICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDT 605
VICR LG+SG A A + FG G G ++L +RC GNE S+ C WGEH C HKED
Sbjct: 316 VICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDA 375
Query: 606 GVIC 617
GV C
Sbjct: 376 GVSC 379
Score = 61.2 bits (147), Expect = 3e-09
Identities = 33/101 (32%), Positives = 49/101 (48%)
Frame = +3
Query: 315 SAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPG 494
S +L G + G VE+ + GT+C + D++ASVIC L + G+ +A G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGAWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
Query: 495 KGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGVIC 617
I SN+RC G+E ++ C+ W C K V C
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC 269
>sp|P30205|WC11_BOVIN Antigen WC1.1 precursor
Length = 1436
Score = 104 bits (259), Expect = 3e-22
Identities = 65/214 (30%), Positives = 95/214 (44%), Gaps = 5/214 (2%)
Frame = +3
Query: 72 LDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQKDKTCIRMSQ 251
+D + C+ + ++ +C PW+ +C +E A + C+ RP +
Sbjct: 1100 VDLIQCRKMDTSLWQCPSGPWKYSSCSPKEEAYISCEGRRP------------------K 1141
Query: 252 ICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVI 431
C C+D +L G SGRVE+ + GT+CDD ++ EA V+
Sbjct: 1142 SCPTAAACTDRE---------KLRLRGGDSECSGRVEVWHNGSWGTVCDDSWSLAEAEVV 1192
Query: 432 CRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWGEHKCSHKEDTGV 611
C+ LG AV + FGPG G I L ++C G E+SL C WG+ C H+ED GV
Sbjct: 1193 CQQLGCGQALEAVRSAAFGPGNGSIWLDEVQCGGRESSLWDCVAEPWGQSDCKHEEDAGV 1252
Query: 612 ICG-----LPPLQQIITTTVISVKKSEQIPGVSC 698
C LP TT S+ +PGV C
Sbjct: 1253 RCSGVRTTLPTTTAGTRTTSNSLPGIFSLPGVLC 1286
Score = 103 bits (256), Expect = 7e-22
Identities = 76/256 (29%), Positives = 107/256 (41%), Gaps = 64/256 (25%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCK---------EDRP 194
FG P I LD L+C G E + C W +HNC+ ++ AGV+C ED+
Sbjct: 431 FGAGSGP-IWLDNLNCTGKESHVWRCPSRGWGQHNCRHKQDAGVICSEFLALRMVSEDQQ 489
Query: 195 C---MNTEFR------CQKDKTCIRMSQIC-------DGTRDCSDGSDE----------- 293
C + + C+ I +S IC GT + S E
Sbjct: 490 CAGWLEVFYNGTWGSVCRNPMEDITVSTICRQLGCGDSGTLNSSVALREGFRPQWVDRIQ 549
Query: 294 ----------------------PEGRCFL------SAKLVDGPDSNSGRVEIKGAYTKGT 389
P+ ++ +LVDG SGRVEI + GT
Sbjct: 550 CRKTDTSLWQCPSDPWNYNSCSPKEEAYIWCADSRQIRLVDGGGRCSGRVEILDQGSWGT 609
Query: 390 ICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFK 569
ICDD + ++A V+C+ LG A V S FG G G I L + C G E+ + C ++
Sbjct: 610 ICDDRWDLDDARVVCKQLGCGEALDATVSSFFGTGSGPIWLDEVNCRGEESQVWRCPSWG 669
Query: 570 WGEHKCSHKEDTGVIC 617
W +H C+H+ED GVIC
Sbjct: 670 WRQHNCNHQEDAGVIC 685
Score = 97.4 bits (241), Expect = 4e-20
Identities = 53/140 (37%), Positives = 70/140 (50%), Gaps = 16/140 (11%)
Frame = +3
Query: 246 SQICDGTR-----DCSDGSDEPEGRCFLS-----------AKLVDGPDSNSGRVEIKGAY 377
S IC G + C+D +P G +LVDG +GRVEI
Sbjct: 336 SVICSGNQIQVLPQCNDSVSQPTGSAASEDSAPYCSDSRQLRLVDGGGPCAGRVEILDQG 395
Query: 378 TKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSC 557
+ GTICDDG+ ++A V+CR LG A + FG G G I L N+ C G E+ + C
Sbjct: 396 SWGTICDDGWDLDDARVVCRQLGCGEALNATGSAHFGAGSGPIWLDNLNCTGKESHVWRC 455
Query: 558 KNFKWGEHKCSHKEDTGVIC 617
+ WG+H C HK+D GVIC
Sbjct: 456 PSRGWGQHNCRHKQDAGVIC 475
Score = 92.0 bits (227), Expect = 2e-18
Identities = 68/206 (33%), Positives = 93/206 (45%), Gaps = 9/206 (4%)
Frame = +3
Query: 27 GAGVRFGKVRNPLILL--DELS-----CKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKE 185
G GV R P ++ D++S C G E + C +C A V+C
Sbjct: 837 GCGVAISTPRGPHLVEGGDQISTAQFHCSGAESFLWSCPVTALGGPDCSHGNTASVICSG 896
Query: 186 DRPCMNTEFRCQKDKTCIRMSQICDGTRDCSDGSDEPEGRCFLSA--KLVDGPDSNSGRV 359
+ +T+ Q + +SQ S S+E C S +LVDG GRV
Sbjct: 897 N----HTQVLPQCNDF---LSQPAG-----SAASEESSPYCSDSRQLRLVDGGGPCGGRV 944
Query: 360 EIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLSNMRCNGNE 539
EI + GTICDD + ++A V+CR LG A + FG G G I L ++ C G E
Sbjct: 945 EILDQGSWGTICDDDWDLDDARVVCRQLGCGEALNATGSAHFGAGSGPIWLDDLNCTGKE 1004
Query: 540 TSLRSCKNFKWGEHKCSHKEDTGVIC 617
+ + C + WG H C HKED GVIC
Sbjct: 1005 SHVWRCPSRGWGRHDCRHKEDAGVIC 1030
Score = 68.2 bits (165), Expect = 3e-11
Identities = 53/195 (27%), Positives = 72/195 (36%), Gaps = 1/195 (0%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQ 221
FG P I LDE++C+G E + C WR+HNC +E AGV+C
Sbjct: 641 FGTGSGP-IWLDEVNCRGEESQVWRCPSWGWRQHNCNHQEDAGVICSG------------ 687
Query: 222 KDKTCIRMSQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDD 401
+L G SGRVE+ + D
Sbjct: 688 -------------------------------FVRLAGGDGPCSGRVEVHSGEAWTPVSDG 716
Query: 402 GFTDNEASVICRMLGISGRALAVVDSR-FGPGKGEIVLSNMRCNGNETSLRSCKNFKWGE 578
FT A VIC LG G+A++V+ F G++ RC+G E L SC
Sbjct: 717 NFTLPTAQVICAELGC-GKAVSVLGHMPFRESDGQVWAEEFRCDGGEPELWSCPRVPCPG 775
Query: 579 HKCSHKEDTGVICGL 623
C H V+C +
Sbjct: 776 GTCLHSGAAQVVCSV 790
Score = 65.1 bits (157), Expect = 2e-10
Identities = 53/194 (27%), Positives = 76/194 (39%), Gaps = 2/194 (1%)
Frame = +3
Query: 42 FGKVRNPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNTEFRCQ 221
FG P I LD+L+C G E + C W +H+C+ +E AGV+C E
Sbjct: 986 FGAGSGP-IWLDDLNCTGKESHVWRCPSRGWGRHDCRHKEDAGVICSE------------ 1032
Query: 222 KDKTCIRMSQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTKGTICDD 401
FL+ ++V +G +E+ T G++C
Sbjct: 1033 -----------------------------FLALRMVSEDQQCAGWLEVFYNGTWGSVCRS 1063
Query: 402 GFTDNEASVICRMLGI--SGRALAVVDSRFGPGKGEIVLSNMRCNGNETSLRSCKNFKWG 575
D SVICR LG SG V R G + L ++C +TSL C + W
Sbjct: 1064 PMEDITVSVICRQLGCGDSGSLNTSVGLREGSRPRWVDL--IQCRKMDTSLWQCPSGPWK 1121
Query: 576 EHKCSHKEDTGVIC 617
CS KE+ + C
Sbjct: 1122 YSSCSPKEEAYISC 1135
Score = 58.5 bits (140), Expect = 2e-08
Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Frame = +3
Query: 312 LSAKLVDGPDSNSGRVEIKGAYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGP 491
L +L DG GRVE+K GT+ +T +ASV+CR LG + FGP
Sbjct: 26 LELRLKDGVHRCEGRVEVKHQGEWGTVDGYRWTLKDASVVCRQLGCGAAIGFPGGAYFGP 85
Query: 492 GKGEIVLSNMRCNGNETSLRSCKNFKWGEHK---CSHKEDTGVIC 617
G G I L C G E+++ C++ +++ +H D GV+C
Sbjct: 86 GLGPIWLLYTSCEGTESTVSDCEHSNIKDYRNDGYNHGRDAGVVC 130
Score = 50.4 bits (119), Expect = 5e-06
Identities = 49/199 (24%), Positives = 65/199 (32%), Gaps = 4/199 (2%)
Frame = +3
Query: 33 GVRFGKVRNPLILLDELSCKGTEFTIEECNHD---PWRKHNCKSEEIAGVVCKEDRPCMN 203
G FG P+ LL SC+GTE T+ +C H +R AGVVC
Sbjct: 80 GAYFGPGLGPIWLL-YTSCEGTESTVSDCEHSNIKDYRNDGYNHGRDAGVVCSG------ 132
Query: 204 TEFRCQKDKTCIRMSQICDGTRDCSDGSDEPEGRCFLSAKLVDGPDSNSGRVEIKGAYTK 383
+L G SGRVE+
Sbjct: 133 -------------------------------------FVRLAGGDGPCSGRVEVHSGEAW 155
Query: 384 GTICDDGFTDNEASVICRMLGISGRALAVVDSR-FGPGKGEIVLSNMRCNGNETSLRSCK 560
+ D FT A +IC LG G+A++V+ F ++ RC G E L C
Sbjct: 156 IPVSDGNFTLATAQIICAELGC-GKAVSVLGHELFRESSAQVWAEEFRCEGEEPELWVCP 214
Query: 561 NFKWGEHKCSHKEDTGVIC 617
C H V+C
Sbjct: 215 RVPCPGGTCHHSGSAQVVC 233
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 6/143 (4%)
Frame = +3
Query: 207 EFRCQKDK----TCIRMSQICDGTRDCSDGSDEPEGRCFLSAKLV-DGPDSNSGRVEIKG 371
EFRC+ ++ C R+ C G GS + + +L+ +G G+VE+
Sbjct: 200 EFRCEGEEPELWVCPRVP--CPGGTCHHSGSAQVVCSAYSEVRLMTNGSSQCEGQVEMNI 257
Query: 372 AYTKGTICDDGFTDNEASVICRMLGISGRALAVVDSRFGPGKGEIVLS-NMRCNGNETSL 548
+ +C ++ A+VICR LG G A++ +G+ +L+ C+G E+ L
Sbjct: 258 SGQWRALCASHWSLANANVICRQLGC-GVAISTPGGPHLVEEGDQILTARFHCSGAESFL 316
Query: 549 RSCKNFKWGEHKCSHKEDTGVIC 617
SC G CSH VIC
Sbjct: 317 WSCPVTALGGPDCSHGNTASVIC 339
Score = 44.3 bits (103), Expect = 4e-04
Identities = 21/50 (42%), Positives = 29/50 (58%)
Frame = +3
Query: 57 NPLILLDELSCKGTEFTIEECNHDPWRKHNCKSEEIAGVVCKEDRPCMNT 206
N I LDE+ C G E ++ +C +PW + +CK EE AGV C R + T
Sbjct: 1214 NGSIWLDEVQCGGRESSLWDCVAEPWGQSDCKHEEDAGVRCSGVRTTLPT 1263
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,407,259
Number of Sequences: 369166
Number of extensions: 2281666
Number of successful extensions: 8397
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7225
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8170
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7570361805
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)