Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00962 (790 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 140 3e-33 sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 139 1e-32 sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 137 3e-32 sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 65 2e-10 sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 64 4e-10 sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 60 7e-09 sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen rece... 54 6e-07 sp|Q924T7|RNF31_MOUSE RING finger protein 31 53 8e-07 sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 52 1e-06 sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 52 2e-06
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein interacting with PKC) (Protein kinase C-binding protein beta-15) Length = 498 Score = 140 bits (354), Expect = 3e-33 Identities = 75/220 (34%), Positives = 108/220 (49%), Gaps = 2/220 (0%) Frame = +3 Query: 18 KVVTFEECNHKFCKKCLRNYIKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHA 197 + V EC H FC++CL+ I+ + V+CPF N + C KL + +LS D+ Sbjct: 281 EAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYS-CPGKLLEREIRALLSPEDYQ 339 Query: 198 SYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHE--NE 371 + ++ + Y C DC G ++ + TC C ++C CKA+HE N Sbjct: 340 RFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHERMNC 399 Query: 372 ESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQHE 551 +D A + Q + ++ EA+YC +C + ++ GCDWI C C E Sbjct: 400 REYQDDLAHRARNDVAAQQTTEMLRVMLQQGEAMYCPQCRIVVQKKDGCDWIRCTVCHTE 459 Query: 552 ICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKCHPDCNNCH 671 IC+ TK RWGP G GD SGGCRC + CHP C NCH Sbjct: 460 ICWVTKGPRWGPGGPGDTSGGCRCRVNG-IPCHPSCQNCH 498
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B virus X-associated protein 4) (HBV-associated factor 4) (RING finger protein 54) Length = 500 Score = 139 bits (349), Expect = 1e-32 Identities = 74/221 (33%), Positives = 111/221 (50%), Gaps = 3/221 (1%) Frame = +3 Query: 18 KVVTFEECNHKFCKKCLRNYIKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHA 197 + V EC H FC++CL+ I+ + V+CPF N + C KL + +L+ D+ Sbjct: 283 EAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYS-CSGKLLEREIKALLTPEDYQ 341 Query: 198 SYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHEN--- 368 + ++ + Y C DC G ++ + TC C ++C CKA+HE Sbjct: 342 RFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNC 401 Query: 369 EESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQH 548 +E ED + + R ++L + ++ EA+ C +C + ++ GCDWI C C Sbjct: 402 KEYQEDLALRAQNDVAARQTTEML-KVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHT 460 Query: 549 EICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKCHPDCNNCH 671 EIC+ TK RWGP G GD SGGCRC + CHP C NCH Sbjct: 461 EICWVTKGPRWGPGGPGDTSGGCRCRVNG-IPCHPSCQNCH 500
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3 (UbcM4-interacting protein 28) Length = 498 Score = 137 bits (346), Expect = 3e-32 Identities = 73/221 (33%), Positives = 111/221 (50%), Gaps = 3/221 (1%) Frame = +3 Query: 18 KVVTFEECNHKFCKKCLRNYIKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHA 197 + V EC H FC++CL+ I+ + V CPF + + C KL + +LS D+ Sbjct: 281 EAVVLRECLHTFCRECLQGTIRNSQEAEVACPFIDSTYS-CPGKLLEREIRALLSPEDYQ 339 Query: 198 SYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHEN--- 368 + ++ + Y C DC G ++ + TC C ++C CKA+HE+ Sbjct: 340 RFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHEHMNC 399 Query: 369 EESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQH 548 E +D + + R ++L + ++ EA++C +C + ++ GCDWI C C Sbjct: 400 REYQDDLALRAQNDVAARQTTEML-KVMLQQGEAMHCPQCRIVVQKKDGCDWIRCTVCHT 458 Query: 549 EICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKCHPDCNNCH 671 EIC+ TK RWGP G GD SGGCRC + CHP C NCH Sbjct: 459 EICWVTKGPRWGPGGPGDTSGGCRCRVNG-IPCHPSCQNCH 498
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein) Length = 493 Score = 65.1 bits (157), Expect = 2e-10 Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 10/195 (5%) Frame = +3 Query: 39 CNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHASYN 206 C H+FC+ C + +K+ V+C + C ++ +D F +L N+ Sbjct: 156 CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQ-----DCPLRTPEDFVFPLLP-NEELREK 209 Query: 207 KRRLAHRCFEQS--DLYPCYNSDCSGTVKLNNNQFQHT-CQRCKAISCYKCKALHENEES 377 RR R + +S L C +DC +++ + + C RC + C+KC+ ++ Sbjct: 210 YRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTD 269 Query: 378 C---EDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQH 548 C W K + + N + C KC + +E GGC+ + C C+H Sbjct: 270 CATIRKWLTK------CADDSETANYISAHTKD---CPKCNICIEKNGGCNHMQCSKCKH 320 Query: 549 EICFRTKLSRWGPKG 593 + C+ L W G Sbjct: 321 DFCWMC-LGDWKTHG 334
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48) Length = 492 Score = 64.3 bits (155), Expect = 4e-10 Identities = 44/195 (22%), Positives = 80/195 (41%), Gaps = 10/195 (5%) Frame = +3 Query: 39 CNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHASYN 206 C H+FC+ C + +K+ ++C + C ++ +D F +L N+ Sbjct: 155 CQHQFCRSCWEQHCSVLVKDGVGVGISCMAQ-----DCPLRTPEDFVFPLLP-NEELRDK 208 Query: 207 KRRLAHRCFEQS--DLYPCYNSDCSGTVKLNNNQFQHT-CQRCKAISCYKCKALHENEES 377 RR R + +S L C +DC +++ + + C RC + C+KC+ ++ Sbjct: 209 YRRYLFRDYVESHFQLQLCPGADCPMVIRVQEPRARRVQCNRCSEVFCFKCRQMYHAPTD 268 Query: 378 C---EDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQH 548 C W K + + N + C KC + +E GGC+ + C C+H Sbjct: 269 CATIRKWLTK------CADDSETANYISAHTKD---CPKCNICIEKNGGCNHMQCSKCKH 319 Query: 549 EICFRTKLSRWGPKG 593 + C+ L W G Sbjct: 320 DFCWMC-LGDWKTHG 333
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region Length = 551 Score = 60.1 bits (144), Expect = 7e-09 Identities = 53/216 (24%), Positives = 87/216 (40%), Gaps = 15/216 (6%) Frame = +3 Query: 3 CLEQVKVVTFE-ECNHKFCKKCLRNYIKEWKVYP---VTCPFKGNNENQCDMKLSDDICF 170 C ++ TF EC H++C C R+YIK+ K++ +TC C + L ++ Sbjct: 182 CCDKKDTETFALECGHEYCINCYRHYIKD-KLHEGNIITCM-------DCSLALKNEDID 233 Query: 171 KILSKNDHASYNKRRLAHRCFEQSDLYP-CYNSDCSGTVKLNNNQFQHTCQRCKAISCYK 347 K++ + + + + Y C +DC V L + R K Sbjct: 234 KVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVK 293 Query: 348 CKALHE----------NEESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMF 497 C + H + C+ TA KA R + ++LN E C KC + Sbjct: 294 CNSFHRFCFNCGFEVHSPADCKITTAWVKKA---RKESEILNWVLSHTKE---CPKCSVN 347 Query: 498 LEFVGGCDWICCPCCQHEICFRTKLSRWGPKGKGDF 605 +E GGC+ + C C++E C+ + W P GK F Sbjct: 348 IEKNGGCNHMVCSSCKYEFCWICE-GPWAPHGKNFF 382
>sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) Length = 485 Score = 53.5 bits (127), Expect = 6e-07 Identities = 54/217 (24%), Positives = 83/217 (38%), Gaps = 31/217 (14%) Frame = +3 Query: 30 FEECNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHA 197 F EC H +CK CL++Y IK+ +V + CP E QC + +++ + A Sbjct: 236 FLECKHVYCKACLKDYFEIQIKDGQVKCLNCP-----EPQCPSVATPGQVKELVEADLFA 290 Query: 198 SYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHENEES 377 Y++ L +D+ C C V C C C C+ + Sbjct: 291 RYDRLLLQSTLDLMADVVYCPRPCCQLPVMQEPGGTMAICSSCNFAFCTLCRLTYHGLSP 350 Query: 378 CEDWTAKNGKAINLRNQ---------------------QKLLNEKK----IENNEAIYCM 482 C+ TA+ K I+LRN+ QK L E + +E N C Sbjct: 351 CK-VTAE--KLIDLRNEYLQADEATKRFLEQRYGKRVIQKALEEMESKDWLEKNSK-SCP 406 Query: 483 KCGMFLEFVGGCDWICCPCCQHEICF--RTKLSRWGP 587 CG ++ + GC+ + C C C+ LSR P Sbjct: 407 CCGTPIQKLDGCNKMTCTGCMQYFCWICMGSLSRANP 443
>sp|Q924T7|RNF31_MOUSE RING finger protein 31 Length = 1066 Score = 53.1 bits (126), Expect = 8e-07 Identities = 56/243 (23%), Positives = 85/243 (34%), Gaps = 15/243 (6%) Frame = +3 Query: 39 CNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHASYN 206 C C +C R + +KE + + CP G + D +L + + + Sbjct: 711 CECTICPECFRQHFTIALKEKHITDMVCPACGRPDLTDDAQLLSYFSTLDIQLRESLDPD 770 Query: 207 KRRLAHRCFEQSDLYP----CYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHENE- 371 L H+ ++ L + + CS Q + TC +C C +CK E + Sbjct: 771 AYALFHKKLTEAVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQH 830 Query: 372 --ESCED---WTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFV-GGCDWICC 533 SCED W N + L E I+ C KC GGC C Sbjct: 831 RGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGID------CPKCKFSYALARGGCMHFHC 884 Query: 534 PCCQHEICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKCHPDCNNCH*LKLLSNIYIK*SV 713 C+H+ C GC + AK KC PD NC K L + + + Sbjct: 885 TQCRHQFC-----------------SGCYNAFYAKNKC-PD-PNCKVKKSLHGHHPRDCL 925 Query: 714 YFL 722 ++L Sbjct: 926 FYL 928
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger ubiquitin-associated domain protein) Length = 1072 Score = 52.4 bits (124), Expect = 1e-06 Identities = 55/222 (24%), Positives = 81/222 (36%), Gaps = 15/222 (6%) Frame = +3 Query: 39 CNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSD-----DICFK-ILSKN 188 C C C R + +KE + + CP G + D +L DI + L + Sbjct: 717 CECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPD 776 Query: 189 DHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHEN 368 +A ++K+ C + CS Q + TC +C C +CK E Sbjct: 777 AYALFHKKLTEGVLMRDPKFLWC--AQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEE 834 Query: 369 E---ESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFV-GGCDWICCP 536 + SCED+ +N K +N Q ++ N I C KC GGC C Sbjct: 835 QHRGRSCEDF--QNWKRMNDPEYQAQGLAMYLQEN-GIDCPKCKFSYALARGGCMHFHCT 891 Query: 537 CCQHEICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKC-HPDC 659 C+H+ C GC + AK KC P+C Sbjct: 892 QCRHQFC-----------------SGCYNAFYAKNKCPEPNC 916
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme E2-binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6) Length = 557 Score = 51.6 bits (122), Expect = 2e-06 Identities = 46/194 (23%), Positives = 78/194 (40%), Gaps = 8/194 (4%) Frame = +3 Query: 36 ECNHKFCKKCLRNYI-----KEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHAS 200 EC HKFC +C Y+ +E ++CP G CD+ + D+ ++++ + Sbjct: 202 ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHG-----CDILVDDNTVMRLITDSKVKL 256 Query: 201 YNKRRLAHRCFEQSDLYP-CYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHENEES 377 + + + E + L C DC VK+ + +C C+ C + Sbjct: 257 KYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENWHDPVK 316 Query: 378 CEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICC--PCCQHE 551 C+ W K K + + + N E C KC + +E GGC+ + C C+ E Sbjct: 317 CK-WLKKWIKKCD--DDSETSNWIAANTKE---CPKCHVTIEKDGGCNHMVCRNQNCKAE 370 Query: 552 ICFRTKLSRWGPKG 593 C+ L W P G Sbjct: 371 FCW-VCLGPWEPHG 383
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,408,327 Number of Sequences: 369166 Number of extensions: 1804304 Number of successful extensions: 5427 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5087 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5372 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7454154400 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)