Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_E17
(732 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 140 3e-33
sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 139 1e-32
sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 137 2e-32
sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 65 2e-10
sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 64 3e-10
sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 60 6e-09
sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen rece... 54 6e-07
sp|Q924T7|RNF31_MOUSE RING finger protein 31 53 7e-07
sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 52 1e-06
sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 52 2e-06
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein
interacting with PKC) (Protein kinase C-binding protein
beta-15)
Length = 498
Score = 140 bits (354), Expect = 3e-33
Identities = 75/220 (34%), Positives = 108/220 (49%), Gaps = 2/220 (0%)
Frame = +3
Query: 18 KVVTFEECNHKFCKKCLRNYIKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHA 197
+ V EC H FC++CL+ I+ + V+CPF N + C KL + +LS D+
Sbjct: 281 EAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYS-CPGKLLEREIRALLSPEDYQ 339
Query: 198 SYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHE--NE 371
+ ++ + Y C DC G ++ + TC C ++C CKA+HE N
Sbjct: 340 RFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHERMNC 399
Query: 372 ESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQHE 551
+D A + Q + ++ EA+YC +C + ++ GCDWI C C E
Sbjct: 400 REYQDDLAHRARNDVAAQQTTEMLRVMLQQGEAMYCPQCRIVVQKKDGCDWIRCTVCHTE 459
Query: 552 ICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKCHPDCNNCH 671
IC+ TK RWGP G GD SGGCRC + CHP C NCH
Sbjct: 460 ICWVTKGPRWGPGGPGDTSGGCRCRVNG-IPCHPSCQNCH 498
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B
virus X-associated protein 4) (HBV-associated factor 4)
(RING finger protein 54)
Length = 500
Score = 139 bits (349), Expect = 1e-32
Identities = 74/221 (33%), Positives = 111/221 (50%), Gaps = 3/221 (1%)
Frame = +3
Query: 18 KVVTFEECNHKFCKKCLRNYIKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHA 197
+ V EC H FC++CL+ I+ + V+CPF N + C KL + +L+ D+
Sbjct: 283 EAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYS-CSGKLLEREIKALLTPEDYQ 341
Query: 198 SYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHEN--- 368
+ ++ + Y C DC G ++ + TC C ++C CKA+HE
Sbjct: 342 RFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNC 401
Query: 369 EESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQH 548
+E ED + + R ++L + ++ EA+ C +C + ++ GCDWI C C
Sbjct: 402 KEYQEDLALRAQNDVAARQTTEML-KVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHT 460
Query: 549 EICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKCHPDCNNCH 671
EIC+ TK RWGP G GD SGGCRC + CHP C NCH
Sbjct: 461 EICWVTKGPRWGPGGPGDTSGGCRCRVNG-IPCHPSCQNCH 500
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3
(UbcM4-interacting protein 28)
Length = 498
Score = 137 bits (346), Expect = 2e-32
Identities = 73/221 (33%), Positives = 111/221 (50%), Gaps = 3/221 (1%)
Frame = +3
Query: 18 KVVTFEECNHKFCKKCLRNYIKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHA 197
+ V EC H FC++CL+ I+ + V CPF + + C KL + +LS D+
Sbjct: 281 EAVVLRECLHTFCRECLQGTIRNSQEAEVACPFIDSTYS-CPGKLLEREIRALLSPEDYQ 339
Query: 198 SYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHEN--- 368
+ ++ + Y C DC G ++ + TC C ++C CKA+HE+
Sbjct: 340 RFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHEHMNC 399
Query: 369 EESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQH 548
E +D + + R ++L + ++ EA++C +C + ++ GCDWI C C
Sbjct: 400 REYQDDLALRAQNDVAARQTTEML-KVMLQQGEAMHCPQCRIVVQKKDGCDWIRCTVCHT 458
Query: 549 EICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKCHPDCNNCH 671
EIC+ TK RWGP G GD SGGCRC + CHP C NCH
Sbjct: 459 EICWVTKGPRWGPGGPGDTSGGCRCRVNG-IPCHPSCQNCH 498
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
Length = 493
Score = 65.1 bits (157), Expect = 2e-10
Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 10/195 (5%)
Frame = +3
Query: 39 CNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHASYN 206
C H+FC+ C + +K+ V+C + C ++ +D F +L N+
Sbjct: 156 CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQ-----DCPLRTPEDFVFPLLP-NEELREK 209
Query: 207 KRRLAHRCFEQS--DLYPCYNSDCSGTVKLNNNQFQHT-CQRCKAISCYKCKALHENEES 377
RR R + +S L C +DC +++ + + C RC + C+KC+ ++
Sbjct: 210 YRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTD 269
Query: 378 C---EDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQH 548
C W K + + N + C KC + +E GGC+ + C C+H
Sbjct: 270 CATIRKWLTK------CADDSETANYISAHTKD---CPKCNICIEKNGGCNHMQCSKCKH 320
Query: 549 EICFRTKLSRWGPKG 593
+ C+ L W G
Sbjct: 321 DFCWMC-LGDWKTHG 334
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
(UbcM4-interacting protein 48)
Length = 492
Score = 64.3 bits (155), Expect = 3e-10
Identities = 44/195 (22%), Positives = 80/195 (41%), Gaps = 10/195 (5%)
Frame = +3
Query: 39 CNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHASYN 206
C H+FC+ C + +K+ ++C + C ++ +D F +L N+
Sbjct: 155 CQHQFCRSCWEQHCSVLVKDGVGVGISCMAQ-----DCPLRTPEDFVFPLLP-NEELRDK 208
Query: 207 KRRLAHRCFEQS--DLYPCYNSDCSGTVKLNNNQFQHT-CQRCKAISCYKCKALHENEES 377
RR R + +S L C +DC +++ + + C RC + C+KC+ ++
Sbjct: 209 YRRYLFRDYVESHFQLQLCPGADCPMVIRVQEPRARRVQCNRCSEVFCFKCRQMYHAPTD 268
Query: 378 C---EDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICCPCCQH 548
C W K + + N + C KC + +E GGC+ + C C+H
Sbjct: 269 CATIRKWLTK------CADDSETANYISAHTKD---CPKCNICIEKNGGCNHMQCSKCKH 319
Query: 549 EICFRTKLSRWGPKG 593
+ C+ L W G
Sbjct: 320 DFCWMC-LGDWKTHG 333
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region
Length = 551
Score = 60.1 bits (144), Expect = 6e-09
Identities = 53/216 (24%), Positives = 87/216 (40%), Gaps = 15/216 (6%)
Frame = +3
Query: 3 CLEQVKVVTFE-ECNHKFCKKCLRNYIKEWKVYP---VTCPFKGNNENQCDMKLSDDICF 170
C ++ TF EC H++C C R+YIK+ K++ +TC C + L ++
Sbjct: 182 CCDKKDTETFALECGHEYCINCYRHYIKD-KLHEGNIITCM-------DCSLALKNEDID 233
Query: 171 KILSKNDHASYNKRRLAHRCFEQSDLYP-CYNSDCSGTVKLNNNQFQHTCQRCKAISCYK 347
K++ + + + + Y C +DC V L + R K
Sbjct: 234 KVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVK 293
Query: 348 CKALHE----------NEESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMF 497
C + H + C+ TA KA R + ++LN E C KC +
Sbjct: 294 CNSFHRFCFNCGFEVHSPADCKITTAWVKKA---RKESEILNWVLSHTKE---CPKCSVN 347
Query: 498 LEFVGGCDWICCPCCQHEICFRTKLSRWGPKGKGDF 605
+E GGC+ + C C++E C+ + W P GK F
Sbjct: 348 IEKNGGCNHMVCSSCKYEFCWICE-GPWAPHGKNFF 382
>sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen receptor-associated protein 54)
(Triad2 protein)
Length = 485
Score = 53.5 bits (127), Expect = 6e-07
Identities = 54/217 (24%), Positives = 83/217 (38%), Gaps = 31/217 (14%)
Frame = +3
Query: 30 FEECNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHA 197
F EC H +CK CL++Y IK+ +V + CP E QC + +++ + A
Sbjct: 236 FLECKHVYCKACLKDYFEIQIKDGQVKCLNCP-----EPQCPSVATPGQVKELVEADLFA 290
Query: 198 SYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHENEES 377
Y++ L +D+ C C V C C C C+ +
Sbjct: 291 RYDRLLLQSTLDLMADVVYCPRPCCQLPVMQEPGGTMAICSSCNFAFCTLCRLTYHGLSP 350
Query: 378 CEDWTAKNGKAINLRNQ---------------------QKLLNEKK----IENNEAIYCM 482
C+ TA+ K I+LRN+ QK L E + +E N C
Sbjct: 351 CK-VTAE--KLIDLRNEYLQADEATKRFLEQRYGKRVIQKALEEMESKDWLEKNSK-SCP 406
Query: 483 KCGMFLEFVGGCDWICCPCCQHEICF--RTKLSRWGP 587
CG ++ + GC+ + C C C+ LSR P
Sbjct: 407 CCGTPIQKLDGCNKMTCTGCMQYFCWICMGSLSRANP 443
>sp|Q924T7|RNF31_MOUSE RING finger protein 31
Length = 1066
Score = 53.1 bits (126), Expect = 7e-07
Identities = 56/243 (23%), Positives = 85/243 (34%), Gaps = 15/243 (6%)
Frame = +3
Query: 39 CNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHASYN 206
C C +C R + +KE + + CP G + D +L + + +
Sbjct: 711 CECTICPECFRQHFTIALKEKHITDMVCPACGRPDLTDDAQLLSYFSTLDIQLRESLDPD 770
Query: 207 KRRLAHRCFEQSDLYP----CYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHENE- 371
L H+ ++ L + + CS Q + TC +C C +CK E +
Sbjct: 771 AYALFHKKLTEAVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQH 830
Query: 372 --ESCED---WTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFV-GGCDWICC 533
SCED W N + L E I+ C KC GGC C
Sbjct: 831 RGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGID------CPKCKFSYALARGGCMHFHC 884
Query: 534 PCCQHEICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKCHPDCNNCH*LKLLSNIYIK*SV 713
C+H+ C GC + AK KC PD NC K L + + +
Sbjct: 885 TQCRHQFC-----------------SGCYNAFYAKNKC-PD-PNCKVKKSLHGHHPRDCL 925
Query: 714 YFL 722
++L
Sbjct: 926 FYL 928
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger
ubiquitin-associated domain protein)
Length = 1072
Score = 52.4 bits (124), Expect = 1e-06
Identities = 55/222 (24%), Positives = 81/222 (36%), Gaps = 15/222 (6%)
Frame = +3
Query: 39 CNHKFCKKCLRNY----IKEWKVYPVTCPFKGNNENQCDMKLSD-----DICFK-ILSKN 188
C C C R + +KE + + CP G + D +L DI + L +
Sbjct: 717 CECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPD 776
Query: 189 DHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHEN 368
+A ++K+ C + CS Q + TC +C C +CK E
Sbjct: 777 AYALFHKKLTEGVLMRDPKFLWC--AQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEE 834
Query: 369 E---ESCEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFV-GGCDWICCP 536
+ SCED+ +N K +N Q ++ N I C KC GGC C
Sbjct: 835 QHRGRSCEDF--QNWKRMNDPEYQAQGLAMYLQEN-GIDCPKCKFSYALARGGCMHFHCT 891
Query: 537 CCQHEICFRTKLSRWGPKGKGDFSGGCRCLYDAKTKC-HPDC 659
C+H+ C GC + AK KC P+C
Sbjct: 892 QCRHQFC-----------------SGCYNAFYAKNKCPEPNC 916
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6)
Length = 557
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/194 (23%), Positives = 78/194 (40%), Gaps = 8/194 (4%)
Frame = +3
Query: 36 ECNHKFCKKCLRNYI-----KEWKVYPVTCPFKGNNENQCDMKLSDDICFKILSKNDHAS 200
EC HKFC +C Y+ +E ++CP G CD+ + D+ ++++ +
Sbjct: 202 ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHG-----CDILVDDNTVMRLITDSKVKL 256
Query: 201 YNKRRLAHRCFEQSDLYP-CYNSDCSGTVKLNNNQFQHTCQRCKAISCYKCKALHENEES 377
+ + + E + L C DC VK+ + +C C+ C +
Sbjct: 257 KYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENWHDPVK 316
Query: 378 CEDWTAKNGKAINLRNQQKLLNEKKIENNEAIYCMKCGMFLEFVGGCDWICC--PCCQHE 551
C+ W K K + + + N E C KC + +E GGC+ + C C+ E
Sbjct: 317 CK-WLKKWIKKCD--DDSETSNWIAANTKE---CPKCHVTIEKDGGCNHMVCRNQNCKAE 370
Query: 552 ICFRTKLSRWGPKG 593
C+ L W P G
Sbjct: 371 FCW-VCLGPWEPHG 383
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,054,824
Number of Sequences: 369166
Number of extensions: 1680916
Number of successful extensions: 5182
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4864
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5127
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6534486000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)