Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00951 (1017 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich... 70 1e-11 sp|Q8BZX4|SFR12_MOUSE Splicing factor, arginine/serine-rich... 70 1e-11 sp|Q9JKL7|SFR12_RAT Splicing factor, arginine/serine-rich 1... 70 1e-11 sp|O01159|RSP7_CAEEL Probable splicing factor, arginine/ser... 48 5e-05 sp|Q86U06|RBM23_HUMAN Probable RNA-binding protein 23 (RNA-... 36 0.15 sp|Q14498|RNPC2_HUMAN RNA-binding region containing protein... 36 0.20 sp|Q8VH51|RNPC2_MOUSE RNA-binding region containing protein... 35 0.26 sp|Q12019|MDN1_YEAST Midasin (MIDAS-containing protein) 35 0.26 sp|P38850|RT107_YEAST Regulator of Ty1 transposition protei... 34 0.76 sp|P70388|RAD50_MOUSE DNA repair protein RAD50 (mRad50) 33 0.99
>sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508) Length = 508 Score = 69.7 bits (169), Expect = 1e-11 Identities = 38/90 (42%), Positives = 55/90 (61%), Gaps = 7/90 (7%) Frame = +3 Query: 165 QVLDFFQPVAEVKFIRMAGSDNDSA--AYVEFSEQSAIVKAFGMMGTNLNTRPIMIQHSN 338 Q+L+FF+ V EVKF+RMAG + A+VEF++Q+++ +A G RP+ I HSN Sbjct: 82 QLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSN 141 Query: 339 VAIVKPSNY-----LRGLEETNRRVRDSGS 413 AIVKP + LEE +RVR++ S Sbjct: 142 NAIVKPPEMTPQAAAKELEEVMKRVREAQS 171
>sp|Q8BZX4|SFR12_MOUSE Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich splicing regulatory protein 86) (SRrp86) Length = 494 Score = 69.7 bits (169), Expect = 1e-11 Identities = 38/90 (42%), Positives = 55/90 (61%), Gaps = 7/90 (7%) Frame = +3 Query: 165 QVLDFFQPVAEVKFIRMAGSDNDSA--AYVEFSEQSAIVKAFGMMGTNLNTRPIMIQHSN 338 Q+L+FF+ V EVKF+RMAG + A+VEF++Q+++ +A G RP+ I HSN Sbjct: 85 QLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSN 144 Query: 339 VAIVKPSNY-----LRGLEETNRRVRDSGS 413 AIVKP + LEE +RVR++ S Sbjct: 145 NAIVKPPEMTPQAAAKELEEVMKRVREAQS 174
>sp|Q9JKL7|SFR12_RAT Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich splicing regulatory protein 86) (SRrp86) (SR-related protein of 86 kDa) Length = 494 Score = 69.7 bits (169), Expect = 1e-11 Identities = 38/90 (42%), Positives = 55/90 (61%), Gaps = 7/90 (7%) Frame = +3 Query: 165 QVLDFFQPVAEVKFIRMAGSDNDSA--AYVEFSEQSAIVKAFGMMGTNLNTRPIMIQHSN 338 Q+L+FF+ V EVKF+RMAG + A+VEF++Q+++ +A G RP+ I HSN Sbjct: 85 QLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSN 144 Query: 339 VAIVKPSNY-----LRGLEETNRRVRDSGS 413 AIVKP + LEE +RVR++ S Sbjct: 145 NAIVKPPEMTPQAAAKELEEVMKRVREAQS 174
>sp|O01159|RSP7_CAEEL Probable splicing factor, arginine/serine-rich 7 (p54) Length = 452 Score = 47.8 bits (112), Expect = 5e-05 Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 4/68 (5%) Frame = +3 Query: 165 QVLDFFQPV-AEVKFIRMAGSDND---SAAYVEFSEQSAIVKAFGMMGTNLNTRPIMIQH 332 +VL+ F EV + RMA + + AYVEFS+Q+++ A G RP+ IQH Sbjct: 178 EVLELFNMYFGEVMYARMASGPDALPCAYAYVEFSQQASVCNALQNDGFEFKERPLKIQH 237 Query: 333 SNVAIVKP 356 S VAI+KP Sbjct: 238 SRVAIIKP 245
>sp|Q86U06|RBM23_HUMAN Probable RNA-binding protein 23 (RNA-binding motif protein 23) (RNA-binding region containing protein 4) (Splicing factor SF2) Length = 439 Score = 36.2 bits (82), Expect = 0.15 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%) Frame = +3 Query: 174 DFFQPVAEVKFIRMAGSDND----SAAYVEFSEQSAIVKAFGMMGTNLNTRPIMIQHS 335 DFF V +V+ +R+ N AYVEF E ++ A G+ G L PI++Q S Sbjct: 184 DFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQAS 241
>sp|Q14498|RNPC2_HUMAN RNA-binding region containing protein 2 (Hepatocellular carcinoma protein 1) (Splicing factor HCC1) Length = 530 Score = 35.8 bits (81), Expect = 0.20 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 8/75 (10%) Frame = +3 Query: 174 DFFQPVAEVKFIRMAGSDND----SAAYVEFSEQSAIVKAFGMMGTNLNTRPIMIQHS-- 335 +FF V +V+ +RM N AYVEF + S++ A G+ G + PI++Q S Sbjct: 171 EFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQA 230 Query: 336 --NVAIVKPSNYLRG 374 N A +N +G Sbjct: 231 EKNRAAAMANNLQKG 245
>sp|Q8VH51|RNPC2_MOUSE RNA-binding region containing protein 2 (Coactivator of activating protein 1 and estrogen receptors) (Coactivator of AP-1 and ERs) (Transcription coactivator CAPER) Length = 530 Score = 35.4 bits (80), Expect = 0.26 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 8/75 (10%) Frame = +3 Query: 174 DFFQPVAEVKFIRMAGSDND----SAAYVEFSEQSAIVKAFGMMGTNLNTRPIMIQHS-- 335 +FF V +V+ +RM N AYVEF + S++ A G+ G + PI++Q S Sbjct: 171 EFFSTVGKVRDVRMISDRNSRRSRGIAYVEFVDVSSVRLAIGLTGQRVLGVPIIVQASQA 230 Query: 336 --NVAIVKPSNYLRG 374 N A +N +G Sbjct: 231 EKNRAAAMANNLQKG 245
>sp|Q12019|MDN1_YEAST Midasin (MIDAS-containing protein) Length = 4910 Score = 35.4 bits (80), Expect = 0.26 Identities = 33/119 (27%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Frame = +1 Query: 463 RGNVRDLAKEVDLTKQANLVANQNPVLDDVPNRDLANDRFLDLVEVEVDQ--RTKN*GRG 636 + N +D+ ++ DLT+ A N+N D RD N+ D VE+E D ++ G Sbjct: 4071 QNNNKDVEQDEDLTEDAQ---NENKEQQDKDERDDENED--DAVEMEGDMAGELEDLSNG 4125 Query: 637 QELDQRIVKDEVEAEKNEENDLDLIGNQKEDQDQSVEMNRGMESAKITETNQSMKAKRK 813 +E D D E E +EE D DL + D + ++ +++K +T+Q++ K + Sbjct: 4126 EENDDEDT-DSEEEELDEEID-DLNEDDPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQ 4182
>sp|P38850|RT107_YEAST Regulator of Ty1 transposition protein 107 Length = 1070 Score = 33.9 bits (76), Expect = 0.76 Identities = 16/71 (22%), Positives = 39/71 (54%) Frame = +1 Query: 661 KDEVEAEKNEENDLDLIGNQKEDQDQSVEMNRGMESAKITETNQSMKAKRKTN*RIKNVK 840 K E+ + ++ND+D +KE+++ +++ G + + +T++ + +++TN V Sbjct: 626 KQEIREQSRKKNDIDY---KKEEEETELQVQLGQRTKREIKTSKKNEKEKETNECHIEVD 682 Query: 841 QRNTERSGRKS 873 Q E+ G +S Sbjct: 683 QMTNEKQGEES 693
>sp|P70388|RAD50_MOUSE DNA repair protein RAD50 (mRad50) Length = 1312 Score = 33.5 bits (75), Expect = 0.99 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 14/102 (13%) Frame = +1 Query: 592 VEVEVDQRTKN*GRGQELDQRIVKDEVEAEKNEEN--------DLDLIGNQKEDQDQSV- 744 V E+ Q + R ELDQ + K E E K E+N ++ + N+K D D+S+ Sbjct: 460 VRSELQQLEGSSDRILELDQELTKAERELSKAEKNSSIETLKAEVMSLQNEKADLDRSLR 519 Query: 745 EMNRGMESAK---ITETNQSMKAKRKT--N*RIKNVKQRNTE 855 ++++ ME T T M K KT + +I+ +K R+++ Sbjct: 520 KLDQEMEQLNHHTTTRTQMEMLTKDKTDKDEQIRKIKSRHSD 561
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 90,230,063 Number of Sequences: 369166 Number of extensions: 1683137 Number of successful extensions: 5522 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5251 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5499 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10861812665 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)