Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00945 (901 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P35279|RAB6A_MOUSE Ras-related protein Rab-6A (Rab-6) 315 1e-85 sp|P20340|RAB6A_HUMAN Ras-related protein Rab-6A (Rab-6) 312 7e-85 sp|Q9NRW1|RAB6B_HUMAN Ras-related protein Rab-6B >gi|471170... 308 2e-83 sp|Q22782|RAB6B_CAEEL Ras-related protein Rab-6.2 305 1e-82 sp|P34213|RAB6A_CAEEL Ras-related protein Rab-6.1 298 1e-80 sp|P17608|RYH1_SCHPO GTP-binding protein ryh1 285 1e-76 sp|Q9H0N0|RAB6C_HUMAN Ras-related protein Rab-6C (Rab6-like... 280 5e-75 sp|Q99260|YPT6_YEAST GTP-binding protein YPT6 238 1e-62 sp|Q9WVB1|RAB6A_RAT Ras-related protein Rab-6A (Rab-6) 196 1e-49 sp|P20339|RAB5A_HUMAN Ras-related protein Rab-5A 162 9e-40
>sp|P35279|RAB6A_MOUSE Ras-related protein Rab-6A (Rab-6) Length = 208 Score = 315 bits (807), Expect = 1e-85 Identities = 160/209 (76%), Positives = 178/209 (85%), Gaps = 1/209 (0%) Frame = +2 Query: 29 MPGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDR 208 M G +F PL+KFKLVFLGEQSVGKTSLITRFMYDSFD+TYQATIGIDFLSKTMYLEDR Sbjct: 1 MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 60 Query: 209 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVI 388 T+RLQLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QTTKWIDDVRTERG+DVI Sbjct: 61 TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVI 120 Query: 389 IMLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATELLSREKP 568 IMLVGNKTDL DKR+VS EEGE+KA+EL+VMFIETSAKAGYNVKQLFRR+A L E Sbjct: 121 IMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEST 180 Query: 569 A-MPHEDLVEVRLKDHANEPANNSSNCWC 652 ED+++++L+ +P N C C Sbjct: 181 QDRSREDMIDIKLEKPQEQPV-NEGGCSC 208
>sp|P20340|RAB6A_HUMAN Ras-related protein Rab-6A (Rab-6) Length = 208 Score = 312 bits (800), Expect = 7e-85 Identities = 159/209 (76%), Positives = 178/209 (85%), Gaps = 1/209 (0%) Frame = +2 Query: 29 MPGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDR 208 M G +F PL+KFKLVFLGEQSVGKTSLITRFMYDSFD+TYQATIGIDFLSKTMYLEDR Sbjct: 1 MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 60 Query: 209 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVI 388 T+RLQLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QTTKWIDDVRTERG+DVI Sbjct: 61 TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVI 120 Query: 389 IMLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATELLSREKP 568 IMLVGNKTDL DKR+VS EEGE+KA+EL+VMFIETSAKAGYNVKQLFRR+A L E Sbjct: 121 IMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEST 180 Query: 569 A-MPHEDLVEVRLKDHANEPANNSSNCWC 652 ED+++++L+ +P + C C Sbjct: 181 QDRSREDMIDIKLEKPQEQPV-SEGGCSC 208
>sp|Q9NRW1|RAB6B_HUMAN Ras-related protein Rab-6B sp|P61294|RAB6B_MOUSE Ras-related protein Rab-6B Length = 208 Score = 308 bits (788), Expect = 2e-83 Identities = 156/209 (74%), Positives = 177/209 (84%), Gaps = 1/209 (0%) Frame = +2 Query: 29 MPGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDR 208 M G +F PL+KFKLVFLGEQSVGKTSLITRFMYDSFD+TYQATIGIDFLSKTMYLEDR Sbjct: 1 MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 60 Query: 209 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVI 388 T+RLQLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QT+KWIDDVRTERG+DVI Sbjct: 61 TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVI 120 Query: 389 IMLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATELLSREK- 565 IMLVGNKTDL DKR+++ EEGE++A+ELSVMFIETSAK GYNVKQLFRR+A+ L E Sbjct: 121 IMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENV 180 Query: 566 PAMPHEDLVEVRLKDHANEPANNSSNCWC 652 E +++++L D EP + C C Sbjct: 181 QEKSKEGMIDIKL-DKPQEPPASEGGCSC 208
>sp|Q22782|RAB6B_CAEEL Ras-related protein Rab-6.2 Length = 205 Score = 305 bits (780), Expect = 1e-82 Identities = 154/206 (74%), Positives = 178/206 (86%), Gaps = 2/206 (0%) Frame = +2 Query: 41 AEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRL 220 ++F PL+KFKLVFLGEQSVGKTSLITRFMYDSFD+TYQATIGIDFLSKTMYLEDRT+RL Sbjct: 2 SDFGNPLKKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRL 61 Query: 221 QLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVIIMLV 400 QLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF+QT+KWIDDVRTERG+DVIIMLV Sbjct: 62 QLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNSNSFHQTSKWIDDVRTERGSDVIIMLV 121 Query: 401 GNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATEL--LSREKPAM 574 GNKTDL DKR+V+T+EGE+KA+EL+VMFIETSAKAGYNVKQLFRRIA L + ++ P Sbjct: 122 GNKTDLSDKRQVTTDEGERKAKELNVMFIETSAKAGYNVKQLFRRIAGALPGIIKDDPVE 181 Query: 575 PHEDLVEVRLKDHANEPANNSSNCWC 652 P + ++ + + +CWC Sbjct: 182 PPNVVTMDPIRQ--RQIVTDEGSCWC 205
>sp|P34213|RAB6A_CAEEL Ras-related protein Rab-6.1 Length = 205 Score = 298 bits (763), Expect = 1e-80 Identities = 151/177 (85%), Positives = 164/177 (92%), Gaps = 3/177 (1%) Frame = +2 Query: 59 LQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 238 L+KFKLVFLGEQSVGKTS+ITRFMYDSFD+TYQATIGIDFLSKTMYLEDRTIRLQLWDTA Sbjct: 9 LKKFKLVFLGEQSVGKTSIITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 68 Query: 239 GQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVIIMLVGNKTDL 418 GQERFRSLIPSYIRDSSVAVVVYDITN NSF+QTTKW+DDVR ERG DVII+LVGNKTDL Sbjct: 69 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTTKWVDDVRNERGCDVIIVLVGNKTDL 128 Query: 419 VDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATEL---LSREKPAMPH 580 DKR+VSTE+GEKKAR+L+VMFIETSAKAGYNVKQLFR+IAT L + E P P+ Sbjct: 129 ADKRQVSTEDGEKKARDLNVMFIETSAKAGYNVKQLFRKIATALPGIVQEETPEQPN 185
>sp|P17608|RYH1_SCHPO GTP-binding protein ryh1 Length = 201 Score = 285 bits (729), Expect = 1e-76 Identities = 145/202 (71%), Positives = 167/202 (82%) Frame = +2 Query: 47 FSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRLQL 226 +S L+KFKLVFLGEQSVGKTSLITRFMYD FD+TYQATIGIDFLSKTMYLEDRT+RLQL Sbjct: 5 YSFSLRKFKLVFLGEQSVGKTSLITRFMYDQFDNTYQATIGIDFLSKTMYLEDRTVRLQL 64 Query: 227 WDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVIIMLVGN 406 WDTAGQERFRSLIPSYIRDSSVA++VYDITN NSF T KWI+DVR ERG DVII+LVGN Sbjct: 65 WDTAGQERFRSLIPSYIRDSSVAIIVYDITNHNSFVNTEKWIEDVRAERGDDVIIVLVGN 124 Query: 407 KTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATELLSREKPAMPHED 586 KTDL DKR+V+ EEGEKKA+EL +M +ETSAKAG+NVK LFR+IA L P M + + Sbjct: 125 KTDLADKRQVTQEEGEKKAKELKIMHMETSAKAGHNVKLLFRKIAQML-----PGMENVE 179 Query: 587 LVEVRLKDHANEPANNSSNCWC 652 ++ D + +P N S+C C Sbjct: 180 TQSTQMIDVSIQPNENESSCNC 201
>sp|Q9H0N0|RAB6C_HUMAN Ras-related protein Rab-6C (Rab6-like protein WTH3) Length = 254 Score = 280 bits (715), Expect = 5e-75 Identities = 154/252 (61%), Positives = 181/252 (71%), Gaps = 4/252 (1%) Frame = +2 Query: 29 MPGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDR 208 M G +F PL+KFKLVFLGEQSV KTSLITRF YDSFD+TYQA IGIDFLSKTMYLED Sbjct: 1 MSAGGDFGNPLRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDG 60 Query: 209 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVI 388 TI L+LWDTAGQER RSLIP YIRDS+ AVVVYDITN NSF QTTKWIDDVRTERG+DVI Sbjct: 61 TIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVI 120 Query: 389 IMLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATELLSREKP 568 I LVGN+TDL DKR+VS EEGE+KA+ L+V FIET AK GYNVKQLFRR+A L E Sbjct: 121 ITLVGNRTDLADKRQVSVEEGERKAKGLNVTFIETRAKTGYNVKQLFRRVAAALPGMEST 180 Query: 569 A-MPHEDLVEVRLKDHANEPANNSSNCWC*NIEELLTI---LPFY*SNNNIDAGLTCFVT 736 ED+ +++L + E + C C + T+ P+ + +++ GL F + Sbjct: 181 QDGSREDMSDIKL-EKPQEQTVSEGGCSCYSPMSSSTLPQKPPYSFIDCSVNIGLNLFPS 239 Query: 737 FHLKCT*SILLV 772 C S+L V Sbjct: 240 LITFCNSSLLPV 251
>sp|Q99260|YPT6_YEAST GTP-binding protein YPT6 Length = 215 Score = 238 bits (608), Expect = 1e-62 Identities = 120/166 (72%), Positives = 141/166 (84%), Gaps = 2/166 (1%) Frame = +2 Query: 59 LQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 238 L K+K+VFLGEQ VGKTSLITRFMYD+FD YQATIGIDFLSKTMYL+D+TIRLQLWDTA Sbjct: 8 LTKYKIVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTA 67 Query: 239 GQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTD-VIIMLVGNKTD 415 GQERFRSLIPSYIRDS VA++VYDIT SF KWI+DV+ ERG + VI+ +VGNK+D Sbjct: 68 GQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYIDKWIEDVKNERGDENVILCIVGNKSD 127 Query: 416 LVDKRKVSTEEGEKKARELSV-MFIETSAKAGYNVKQLFRRIATEL 550 L D+R++STEEGEKKA+ L +F+ETS KAGYNVK LF++IA L Sbjct: 128 LSDERQISTEEGEKKAKLLGAKIFMETSTKAGYNVKALFKKIAKSL 173
>sp|Q9WVB1|RAB6A_RAT Ras-related protein Rab-6A (Rab-6) Length = 140 Score = 196 bits (497), Expect = 1e-49 Identities = 101/141 (71%), Positives = 115/141 (81%), Gaps = 1/141 (0%) Frame = +2 Query: 233 TAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVIIMLVGNKT 412 TAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QTTKWIDDVRTERG+DVIIMLVGNKT Sbjct: 1 TAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKT 60 Query: 413 DLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATELLSREKPA-MPHEDL 589 DL DKR+VS EEGE+KA+EL+VMFIETSAKAGYNVKQLFRR+A L E ED+ Sbjct: 61 DLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDM 120 Query: 590 VEVRLKDHANEPANNSSNCWC 652 ++++L+ +P N C C Sbjct: 121 IDIKLEKPQEQPV-NEGGCSC 140
>sp|P20339|RAB5A_HUMAN Ras-related protein Rab-5A Length = 215 Score = 162 bits (411), Expect = 9e-40 Identities = 84/209 (40%), Positives = 127/209 (60%) Frame = +2 Query: 32 PGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRT 211 P G + +FKLV LGE +VGK+SL+ RF+ F ++TIG FL++T+ L+D T Sbjct: 9 PNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTT 68 Query: 212 IRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVII 391 ++ ++WDTAGQER+ SL P Y R + A+VVYDITN+ SF + W+ +++ + +++I Sbjct: 69 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVI 128 Query: 392 MLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLFRRIATELLSREKPA 571 L GNK DL +KR V +E + A + S++F+ETSAK NV ++F IA + L + +P Sbjct: 129 ALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKK-LPKNEPQ 187 Query: 572 MPHEDLVEVRLKDHANEPANNSSNCWC*N 658 P + R D EP + N C N Sbjct: 188 NPGANSARGRGVD-LTEPTQPTRNQCCSN 215
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 93,264,857 Number of Sequences: 369166 Number of extensions: 1801102 Number of successful extensions: 5624 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5018 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5235 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9078450570 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)