Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_023_O07 (531 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P35279|RAB6A_MOUSE Ras-related protein Rab-6A (Rab-6) 297 1e-80 sp|P20340|RAB6A_HUMAN Ras-related protein Rab-6A (Rab-6) 296 2e-80 sp|Q22782|RAB6B_CAEEL Ras-related protein Rab-6.2 293 2e-79 sp|Q9NRW1|RAB6B_HUMAN Ras-related protein Rab-6B >gi|471170... 291 5e-79 sp|P34213|RAB6A_CAEEL Ras-related protein Rab-6.1 287 1e-77 sp|P17608|RYH1_SCHPO GTP-binding protein ryh1 269 4e-72 sp|Q9H0N0|RAB6C_HUMAN Ras-related protein Rab-6C (Rab6-like... 266 2e-71 sp|Q99260|YPT6_YEAST GTP-binding protein YPT6 233 3e-61 sp|Q9WVB1|RAB6A_RAT Ras-related protein Rab-6A (Rab-6) 177 1e-44 sp|Q9CQD1|RAB5A_MOUSE Ras-related protein Rab-5A 155 4e-38
>sp|P35279|RAB6A_MOUSE Ras-related protein Rab-6A (Rab-6) Length = 208 Score = 297 bits (760), Expect = 1e-80 Identities = 148/167 (88%), Positives = 158/167 (94%) Frame = +2 Query: 29 MPGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDR 208 M G +F PL+KFKLVFLGEQSVGKTSLITRFMYDSFD+TYQATIGIDFLSKTMYLEDR Sbjct: 1 MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 60 Query: 209 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVI 388 T+RLQLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QTTKWIDDVRTERG+DVI Sbjct: 61 TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVI 120 Query: 389 IMLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 IMLVGNKTDL DKR+VS EEGE+KA+EL+VMFIETSAKAGYNVKQLF Sbjct: 121 IMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLF 167
>sp|P20340|RAB6A_HUMAN Ras-related protein Rab-6A (Rab-6) Length = 208 Score = 296 bits (758), Expect = 2e-80 Identities = 148/167 (88%), Positives = 158/167 (94%) Frame = +2 Query: 29 MPGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDR 208 M G +F PL+KFKLVFLGEQSVGKTSLITRFMYDSFD+TYQATIGIDFLSKTMYLEDR Sbjct: 1 MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 60 Query: 209 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVI 388 T+RLQLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QTTKWIDDVRTERG+DVI Sbjct: 61 TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVI 120 Query: 389 IMLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 IMLVGNKTDL DKR+VS EEGE+KA+EL+VMFIETSAKAGYNVKQLF Sbjct: 121 IMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLF 167
>sp|Q22782|RAB6B_CAEEL Ras-related protein Rab-6.2 Length = 205 Score = 293 bits (749), Expect = 2e-79 Identities = 144/163 (88%), Positives = 159/163 (97%) Frame = +2 Query: 41 AEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRL 220 ++F PL+KFKLVFLGEQSVGKTSLITRFMYDSFD+TYQATIGIDFLSKTMYLEDRT+RL Sbjct: 2 SDFGNPLKKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRL 61 Query: 221 QLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVIIMLV 400 QLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF+QT+KWIDDVRTERG+DVIIMLV Sbjct: 62 QLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNSNSFHQTSKWIDDVRTERGSDVIIMLV 121 Query: 401 GNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 GNKTDL DKR+V+T+EGE+KA+EL+VMFIETSAKAGYNVKQLF Sbjct: 122 GNKTDLSDKRQVTTDEGERKAKELNVMFIETSAKAGYNVKQLF 164
>sp|Q9NRW1|RAB6B_HUMAN Ras-related protein Rab-6B sp|P61294|RAB6B_MOUSE Ras-related protein Rab-6B Length = 208 Score = 291 bits (746), Expect = 5e-79 Identities = 144/167 (86%), Positives = 157/167 (94%) Frame = +2 Query: 29 MPGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDR 208 M G +F PL+KFKLVFLGEQSVGKTSLITRFMYDSFD+TYQATIGIDFLSKTMYLEDR Sbjct: 1 MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 60 Query: 209 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVI 388 T+RLQLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QT+KWIDDVRTERG+DVI Sbjct: 61 TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVI 120 Query: 389 IMLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 IMLVGNKTDL DKR+++ EEGE++A+ELSVMFIETSAK GYNVKQLF Sbjct: 121 IMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLF 167
>sp|P34213|RAB6A_CAEEL Ras-related protein Rab-6.1 Length = 205 Score = 287 bits (735), Expect = 1e-77 Identities = 143/157 (91%), Positives = 153/157 (97%) Frame = +2 Query: 59 LQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 238 L+KFKLVFLGEQSVGKTS+ITRFMYDSFD+TYQATIGIDFLSKTMYLEDRTIRLQLWDTA Sbjct: 9 LKKFKLVFLGEQSVGKTSIITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 68 Query: 239 GQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVIIMLVGNKTDL 418 GQERFRSLIPSYIRDSSVAVVVYDITN NSF+QTTKW+DDVR ERG DVII+LVGNKTDL Sbjct: 69 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTTKWVDDVRNERGCDVIIVLVGNKTDL 128 Query: 419 VDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 DKR+VSTE+GEKKAR+L+VMFIETSAKAGYNVKQLF Sbjct: 129 ADKRQVSTEDGEKKARDLNVMFIETSAKAGYNVKQLF 165
>sp|P17608|RYH1_SCHPO GTP-binding protein ryh1 Length = 201 Score = 269 bits (687), Expect = 4e-72 Identities = 133/161 (82%), Positives = 147/161 (91%) Frame = +2 Query: 47 FSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRLQL 226 +S L+KFKLVFLGEQSVGKTSLITRFMYD FD+TYQATIGIDFLSKTMYLEDRT+RLQL Sbjct: 5 YSFSLRKFKLVFLGEQSVGKTSLITRFMYDQFDNTYQATIGIDFLSKTMYLEDRTVRLQL 64 Query: 227 WDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVIIMLVGN 406 WDTAGQERFRSLIPSYIRDSSVA++VYDITN NSF T KWI+DVR ERG DVII+LVGN Sbjct: 65 WDTAGQERFRSLIPSYIRDSSVAIIVYDITNHNSFVNTEKWIEDVRAERGDDVIIVLVGN 124 Query: 407 KTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 KTDL DKR+V+ EEGEKKA+EL +M +ETSAKAG+NVK LF Sbjct: 125 KTDLADKRQVTQEEGEKKAKELKIMHMETSAKAGHNVKLLF 165
>sp|Q9H0N0|RAB6C_HUMAN Ras-related protein Rab-6C (Rab6-like protein WTH3) Length = 254 Score = 266 bits (680), Expect = 2e-71 Identities = 134/167 (80%), Positives = 145/167 (86%) Frame = +2 Query: 29 MPGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDR 208 M G +F PL+KFKLVFLGEQSV KTSLITRF YDSFD+TYQA IGIDFLSKTMYLED Sbjct: 1 MSAGGDFGNPLRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDG 60 Query: 209 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVI 388 TI L+LWDTAGQER RSLIP YIRDS+ AVVVYDITN NSF QTTKWIDDVRTERG+DVI Sbjct: 61 TIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVI 120 Query: 389 IMLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 I LVGN+TDL DKR+VS EEGE+KA+ L+V FIET AK GYNVKQLF Sbjct: 121 ITLVGNRTDLADKRQVSVEEGERKAKGLNVTFIETRAKTGYNVKQLF 167
>sp|Q99260|YPT6_YEAST GTP-binding protein YPT6 Length = 215 Score = 233 bits (593), Expect = 3e-61 Identities = 117/159 (73%), Positives = 136/159 (85%), Gaps = 2/159 (1%) Frame = +2 Query: 59 LQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 238 L K+K+VFLGEQ VGKTSLITRFMYD+FD YQATIGIDFLSKTMYL+D+TIRLQLWDTA Sbjct: 8 LTKYKIVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTA 67 Query: 239 GQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTD-VIIMLVGNKTD 415 GQERFRSLIPSYIRDS VA++VYDIT SF KWI+DV+ ERG + VI+ +VGNK+D Sbjct: 68 GQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYIDKWIEDVKNERGDENVILCIVGNKSD 127 Query: 416 LVDKRKVSTEEGEKKARELSV-MFIETSAKAGYNVKQLF 529 L D+R++STEEGEKKA+ L +F+ETS KAGYNVK LF Sbjct: 128 LSDERQISTEEGEKKAKLLGAKIFMETSTKAGYNVKALF 166
>sp|Q9WVB1|RAB6A_RAT Ras-related protein Rab-6A (Rab-6) Length = 140 Score = 177 bits (450), Expect = 1e-44 Identities = 89/99 (89%), Positives = 95/99 (95%) Frame = +2 Query: 233 TAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVIIMLVGNKT 412 TAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QTTKWIDDVRTERG+DVIIMLVGNKT Sbjct: 1 TAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKT 60 Query: 413 DLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 DL DKR+VS EEGE+KA+EL+VMFIETSAKAGYNVKQLF Sbjct: 61 DLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLF 99
>sp|Q9CQD1|RAB5A_MOUSE Ras-related protein Rab-5A Length = 215 Score = 155 bits (393), Expect = 4e-38 Identities = 72/166 (43%), Positives = 110/166 (66%) Frame = +2 Query: 32 PGGAEFSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRT 211 P G + +FKLV LGE +VGK+SL+ RF+ F ++TIG FL++T+ L+D T Sbjct: 9 PNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTT 68 Query: 212 IRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERGTDVII 391 ++ ++WDTAGQER+ SL P Y R + A+VVYDITN+ SF + W+ +++ + +++I Sbjct: 69 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVI 128 Query: 392 MLVGNKTDLVDKRKVSTEEGEKKARELSVMFIETSAKAGYNVKQLF 529 L GNK DL +KR V +E + A + S++F+ETSAK NV ++F Sbjct: 129 ALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIF 174
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 57,068,979 Number of Sequences: 369166 Number of extensions: 1059866 Number of successful extensions: 4004 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3530 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3650 length of database: 68,354,980 effective HSP length: 103 effective length of database: 49,327,275 effective search space used: 3600891075 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)