Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00931 (974 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9JMD3|PCTL_MOUSE PCTP-like protein (PCTP-L) (StAR-relat... 230 5e-60 sp|Q9Y365|PCTL_HUMAN PCTP-like protein (PCTP-L) (StAR-relat... 226 6e-59 sp|Q8K031|STAR8_MOUSE StAR-related lipid transfer protein 8... 61 5e-09 sp|Q92502|STAR8_HUMAN StAR-related lipid transfer protein 8... 61 5e-09 sp|Q99NB7|CACH1_RAT Cytoplasmic acetyl-CoA hydrolase 1 (CAC... 57 6e-08 sp|Q8R1R3|STAR7_MOUSE StAR-related lipid transfer protein 7... 54 5e-07 sp|P53808|PPCT_MOUSE Phosphatidylcholine transfer protein (... 54 5e-07 sp|Q9NQZ5|STAR7_HUMAN StAR-related lipid transfer protein 7... 54 9e-07 sp|Q9DBK0|CACH1_MOUSE Cytoplasmic acetyl-CoA hydrolase 1 (C... 52 3e-06 sp|P53809|PPCT_RAT Phosphatidylcholine transfer protein (PC... 50 7e-06
>sp|Q9JMD3|PCTL_MOUSE PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog) Length = 291 Score = 230 bits (586), Expect = 5e-60 Identities = 107/239 (44%), Positives = 148/239 (61%), Gaps = 1/239 (0%) Frame = +1 Query: 10 FMSICDNHDGWSIEVNKPDLQIWCKAAP-DSDFKIVKLKSNLKDVGAGVMYDVLHDPDYR 186 F S C+ GW++ +K + +W +A D +K + DV A +YDVLHD +YR Sbjct: 33 FRSECEAEVGWNLTYSKAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYR 92 Query: 187 KVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTEYIIFNHSVFH 366 K WD +I++ DI + N D+GYY+ R P P KNRD +T RSWL +YII N+SV H Sbjct: 93 KKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKH 152 Query: 367 KEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVM 546 + PP+K +RA+S TGYLI+ CV+TY+AQ DP+G LP W VNK++Q++APK M Sbjct: 153 PKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAM 212 Query: 547 TRLLKAALKYPAWKKKHNPDLKPWLYPEQLQLPRINFDHIITTPDFQDNTLDESEVTET 723 ++ KA +KYP WK+KH P KPWL+PEQ LP + + +DES VTE+ Sbjct: 213 KKMYKACIKYPEWKQKHQPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVTES 271
>sp|Q9Y365|PCTL_HUMAN PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28) Length = 291 Score = 226 bits (577), Expect = 6e-59 Identities = 106/239 (44%), Positives = 147/239 (61%), Gaps = 1/239 (0%) Frame = +1 Query: 10 FMSICDNHDGWSIEVNKPDLQIWCKAAP-DSDFKIVKLKSNLKDVGAGVMYDVLHDPDYR 186 F S C+ GW++ ++ + +W +A D +K + DV A +YDVLHD +YR Sbjct: 33 FRSECEAEVGWNLTYSRAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYR 92 Query: 187 KVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTEYIIFNHSVFH 366 K WD +I++ DI + N D+GYY+ R P P KNRD +T RSWL +YII N+SV H Sbjct: 93 KKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKH 152 Query: 367 KEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVM 546 + PP+K +RA+S TGYLI+ CV+TY+AQ DP+G LP W VNK++Q++APK M Sbjct: 153 PKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAM 212 Query: 547 TRLLKAALKYPAWKKKHNPDLKPWLYPEQLQLPRINFDHIITTPDFQDNTLDESEVTET 723 ++ KA LKYP WK+KH P KPWL+PEQ LP + + +DES V E+ Sbjct: 213 KKMYKACLKYPEWKQKHLPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVAES 271
>sp|Q8K031|STAR8_MOUSE StAR-related lipid transfer protein 8 (StARD8) (START domain-containing protein 8) Length = 851 Score = 60.8 bits (146), Expect = 5e-09 Identities = 40/158 (25%), Positives = 72/158 (45%), Gaps = 2/158 (1%) Frame = +1 Query: 37 GWSIEVNKPDLQIWCKAAPDSD-FKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIK 213 GW+ ++ C+ APD ++ K + + A V++ VL + R +WD +++ Sbjct: 665 GWTNVPGPQHTELACRKAPDGHPLRMWKASTEVAAPPAVVLHRVLRE---RALWDEDLLR 721 Query: 214 SKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQT-PTEYIIFNHSVFHKEMPPQKS 390 ++ + + P ++ +Y S P RDFV R W P + E P +S Sbjct: 722 AQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPES 781 Query: 391 FIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAW 504 +RA+ + YL+ P LT++ + D RG+ P W Sbjct: 782 GVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDW 819
>sp|Q92502|STAR8_HUMAN StAR-related lipid transfer protein 8 (StARD8) (START domain-containing protein 8) Length = 1023 Score = 60.8 bits (146), Expect = 5e-09 Identities = 40/158 (25%), Positives = 71/158 (44%), Gaps = 2/158 (1%) Frame = +1 Query: 37 GWSIEVNKPDLQIWCKAAPDSD-FKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIK 213 GW ++ C+ APD ++ K + + A V++ VL + R +WD +++ Sbjct: 837 GWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRE---RALWDEDLLR 893 Query: 214 SKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQT-PTEYIIFNHSVFHKEMPPQKS 390 ++ + + P ++ +Y S P RDFV R W P + E P +S Sbjct: 894 AQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPES 953 Query: 391 FIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAW 504 +RA+ + YL+ P LT++ + D RG+ P W Sbjct: 954 GVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDW 991
>sp|Q99NB7|CACH1_RAT Cytoplasmic acetyl-CoA hydrolase 1 (CACH-1) (rACH) (Acyl-CoA thioesterase 12) Length = 556 Score = 57.4 bits (137), Expect = 6e-08 Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 5/151 (3%) Frame = +1 Query: 37 GWSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVG--AGVMYDVLHDPDYRKVWDRGMI 210 GW I ++I+ + D VK++ K VG A V Y +L D R +WD I Sbjct: 368 GWEITTTLEKIKIY--TLEEQDAISVKVE---KQVGSPARVAYHLLSDFTKRPLWDPHYI 422 Query: 211 KSKDICMINPNNDIGYYALRSPPPFKNRDFV---TQRSWLQTPTEYIIFNHSVFHKEMPP 381 + I ++ ++ I Y K +DFV +QR L+ YI+ SV +PP Sbjct: 423 SCEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSQRKPLKDDNTYIVALMSVVLPSVPP 482 Query: 382 QKSFIRAISQLTGYLIRPLENNGCVLTYVAQ 474 +IR+ G+LI+P++++ C + Y+ Q Sbjct: 483 SPQYIRSQVICAGFLIQPVDSSSCTVAYLNQ 513
>sp|Q8R1R3|STAR7_MOUSE StAR-related lipid transfer protein 7 (StARD7) (START domain-containing protein 7) Length = 295 Score = 54.3 bits (129), Expect = 5e-07 Identities = 42/189 (22%), Positives = 80/189 (42%), Gaps = 6/189 (3%) Frame = +1 Query: 25 DNHDGWSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRG 204 D + W + ++K ++W + + ++ DV ++V D +YRK WD Sbjct: 61 DKEEPWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDAL 120 Query: 205 MIKSKDICM-INPNNDIGYYALRSPPPFKNRDFVTQRSWL--QTPTEYIIFNHSVFHKEM 375 +IK + I +++ ++ P P +RD+V R + Q ++ + +V H + Sbjct: 121 VIKLEVIERDAVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSV 180 Query: 376 PPQKSFIRAISQLTGYLIRP---LENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVM 546 P F+R S + +IRP + NG +P+ P + V+ P + Sbjct: 181 PESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFL 240 Query: 547 TRLLKAALK 573 +L A LK Sbjct: 241 EKLHMATLK 249
>sp|P53808|PPCT_MOUSE Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid transfer protein 2) (StARD2) (START domain-containing protein 2) Length = 214 Score = 54.3 bits (129), Expect = 5e-07 Identities = 40/183 (21%), Positives = 73/183 (39%), Gaps = 4/183 (2%) Frame = +1 Query: 40 WSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIKSK 219 W + V + I+ S K+ L+ ++ DV D DYRK WD+ + + Sbjct: 30 WQLLVEASGITIYRLLDQPSGLYEYKVFGVLEGCSPALLTDVYMDLDYRKQWDQYVKELY 89 Query: 220 DICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTE----YIIFNHSVFHKEMPPQK 387 + + + Y+ ++ P P NRD+V R + Y++ S+ + P + Sbjct: 90 E--KESDEQMVAYWEVKYPFPLSNRDYVYTRQRRDLDVDRRKIYVVLAQSISAPQFPEKS 147 Query: 388 SFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVMTRLLKAA 567 IR I G + +P G++P+W +N A + P + ++KA Sbjct: 148 GVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIPSWLINWAAKNGVPNFLKDMVKAC 207 Query: 568 LKY 576 Y Sbjct: 208 QNY 210
>sp|Q9NQZ5|STAR7_HUMAN StAR-related lipid transfer protein 7 (StARD7) (START domain-containing protein 7) (GTT1 protein) Length = 295 Score = 53.5 bits (127), Expect = 9e-07 Identities = 41/184 (22%), Positives = 79/184 (42%), Gaps = 6/184 (3%) Frame = +1 Query: 40 WSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIKSK 219 W + ++K ++W + + ++ DV ++V D +YRK WD +IK + Sbjct: 66 WEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLE 125 Query: 220 DICM-INPNNDIGYYALRSPPPFKNRDFVTQRSWL--QTPTEYIIFNHSVFHKEMPPQKS 390 I + +++ ++ P P +RD+V R + Q ++ + +V H +P Sbjct: 126 VIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNMMVLVSRAVEHPSVPESPE 185 Query: 391 FIRAISQLTGYLIRP---LENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVMTRLLK 561 F+R S + +IRP + NG +P+ P + V+ P + +L Sbjct: 186 FVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHM 245 Query: 562 AALK 573 A LK Sbjct: 246 ATLK 249
>sp|Q9DBK0|CACH1_MOUSE Cytoplasmic acetyl-CoA hydrolase 1 (CACH-1) (mCACH-1) (Acyl-CoA thioesterase 12) Length = 556 Score = 52.0 bits (123), Expect = 3e-06 Identities = 39/150 (26%), Positives = 68/150 (45%), Gaps = 4/150 (2%) Frame = +1 Query: 37 GWSIEVNKPDLQIWCKAAPDS-DFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIK 213 GW I ++I+ D+ K+ KL + A + Y +L D R +WD I Sbjct: 368 GWEITTTLEKIKIYTLEEQDAISVKVEKLVGS----PAHIAYHLLSDLTKRPLWDPHYIS 423 Query: 214 SKDICMINPNNDIGYYALRSPPPFKNRDFV---TQRSWLQTPTEYIIFNHSVFHKEMPPQ 384 + I ++ ++ I Y K +DFV ++R L+ Y + SV +P Sbjct: 424 CEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSRRKPLKDNNTYTVALRSVVLPSVPSS 483 Query: 385 KSFIRAISQLTGYLIRPLENNGCVLTYVAQ 474 +IR+ G+LI+ +++N C +TY+ Q Sbjct: 484 PQYIRSEVICAGFLIQAVDSNSCTVTYLNQ 513
>sp|P53809|PPCT_RAT Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid transfer protein 2) (StARD2) (START domain-containing protein 2) Length = 214 Score = 50.4 bits (119), Expect = 7e-06 Identities = 38/183 (20%), Positives = 72/183 (39%), Gaps = 4/183 (2%) Frame = +1 Query: 40 WSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIKSK 219 W + V + I+ + K+ L+ ++ DV D DYRK WD+ + + Sbjct: 30 WQLLVEASGITIYRLLDQSTGLYEYKVFGVLESCIPSLLADVYMDLDYRKKWDQYVKELY 89 Query: 220 DICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTE----YIIFNHSVFHKEMPPQK 387 + + Y+ ++ P P NRD+V R + Y++ ++ + P + Sbjct: 90 EKSF--DGQMVAYWEVKYPFPLSNRDYVYTRQRRDLDVDGRKIYVVLAQNISVPQFPEKS 147 Query: 388 SFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVMTRLLKAA 567 IR I G + +P G++P+W +N A + P + ++KA Sbjct: 148 GVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIPSWLINWAAKNGVPSFLKDMVKAC 207 Query: 568 LKY 576 Y Sbjct: 208 QNY 210
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 117,000,358 Number of Sequences: 369166 Number of extensions: 2458765 Number of successful extensions: 5535 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5325 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5520 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10191921135 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)