Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_I19
(805 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9JMD3|PCTL_MOUSE PCTP-like protein (PCTP-L) (StAR-relat... 230 4e-60
sp|Q9Y365|PCTL_HUMAN PCTP-like protein (PCTP-L) (StAR-relat... 226 4e-59
sp|Q8K031|STAR8_MOUSE StAR-related lipid transfer protein 8... 61 4e-09
sp|Q92502|STAR8_HUMAN StAR-related lipid transfer protein 8... 61 4e-09
sp|Q99NB7|CACH1_RAT Cytoplasmic acetyl-CoA hydrolase 1 (CAC... 57 5e-08
sp|Q8R1R3|STAR7_MOUSE StAR-related lipid transfer protein 7... 54 4e-07
sp|P53808|PPCT_MOUSE Phosphatidylcholine transfer protein (... 54 4e-07
sp|Q9NQZ5|STAR7_HUMAN StAR-related lipid transfer protein 7... 54 7e-07
sp|Q9DBK0|CACH1_MOUSE Cytoplasmic acetyl-CoA hydrolase 1 (C... 52 2e-06
sp|P53809|PPCT_RAT Phosphatidylcholine transfer protein (PC... 50 6e-06
>sp|Q9JMD3|PCTL_MOUSE PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10)
(StARD10) (START domain-containing protein 10)
(Serologically defined colon cancer antigen 28 homolog)
Length = 291
Score = 230 bits (586), Expect = 4e-60
Identities = 107/239 (44%), Positives = 148/239 (61%), Gaps = 1/239 (0%)
Frame = +1
Query: 10 FMSICDNHDGWSIEVNKPDLQIWCKAAP-DSDFKIVKLKSNLKDVGAGVMYDVLHDPDYR 186
F S C+ GW++ +K + +W +A D +K + DV A +YDVLHD +YR
Sbjct: 33 FRSECEAEVGWNLTYSKAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYR 92
Query: 187 KVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTEYIIFNHSVFH 366
K WD +I++ DI + N D+GYY+ R P P KNRD +T RSWL +YII N+SV H
Sbjct: 93 KKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKH 152
Query: 367 KEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVM 546
+ PP+K +RA+S TGYLI+ CV+TY+AQ DP+G LP W VNK++Q++APK M
Sbjct: 153 PKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAM 212
Query: 547 TRLLKAALKYPAWKKKHNPDLKPWLYPEQLQLPRINFDHIITTPDFQDNTLDESEVTET 723
++ KA +KYP WK+KH P KPWL+PEQ LP + + +DES VTE+
Sbjct: 213 KKMYKACIKYPEWKQKHQPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVTES 271
>sp|Q9Y365|PCTL_HUMAN PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10)
(StARD10) (START domain-containing protein 10)
(Serologically defined colon cancer antigen 28) (Antigen
NY-CO-28)
Length = 291
Score = 226 bits (577), Expect = 4e-59
Identities = 106/239 (44%), Positives = 147/239 (61%), Gaps = 1/239 (0%)
Frame = +1
Query: 10 FMSICDNHDGWSIEVNKPDLQIWCKAAP-DSDFKIVKLKSNLKDVGAGVMYDVLHDPDYR 186
F S C+ GW++ ++ + +W +A D +K + DV A +YDVLHD +YR
Sbjct: 33 FRSECEAEVGWNLTYSRAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYR 92
Query: 187 KVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTEYIIFNHSVFH 366
K WD +I++ DI + N D+GYY+ R P P KNRD +T RSWL +YII N+SV H
Sbjct: 93 KKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKH 152
Query: 367 KEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVM 546
+ PP+K +RA+S TGYLI+ CV+TY+AQ DP+G LP W VNK++Q++APK M
Sbjct: 153 PKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAM 212
Query: 547 TRLLKAALKYPAWKKKHNPDLKPWLYPEQLQLPRINFDHIITTPDFQDNTLDESEVTET 723
++ KA LKYP WK+KH P KPWL+PEQ LP + + +DES V E+
Sbjct: 213 KKMYKACLKYPEWKQKHLPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVAES 271
>sp|Q8K031|STAR8_MOUSE StAR-related lipid transfer protein 8 (StARD8) (START
domain-containing protein 8)
Length = 851
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/158 (25%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +1
Query: 37 GWSIEVNKPDLQIWCKAAPDSD-FKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIK 213
GW+ ++ C+ APD ++ K + + A V++ VL + R +WD +++
Sbjct: 665 GWTNVPGPQHTELACRKAPDGHPLRMWKASTEVAAPPAVVLHRVLRE---RALWDEDLLR 721
Query: 214 SKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQT-PTEYIIFNHSVFHKEMPPQKS 390
++ + + P ++ +Y S P RDFV R W P + E P +S
Sbjct: 722 AQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPES 781
Query: 391 FIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAW 504
+RA+ + YL+ P LT++ + D RG+ P W
Sbjct: 782 GVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDW 819
>sp|Q92502|STAR8_HUMAN StAR-related lipid transfer protein 8 (StARD8) (START
domain-containing protein 8)
Length = 1023
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/158 (25%), Positives = 71/158 (44%), Gaps = 2/158 (1%)
Frame = +1
Query: 37 GWSIEVNKPDLQIWCKAAPDSD-FKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIK 213
GW ++ C+ APD ++ K + + A V++ VL + R +WD +++
Sbjct: 837 GWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRE---RALWDEDLLR 893
Query: 214 SKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQT-PTEYIIFNHSVFHKEMPPQKS 390
++ + + P ++ +Y S P RDFV R W P + E P +S
Sbjct: 894 AQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPES 953
Query: 391 FIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAW 504
+RA+ + YL+ P LT++ + D RG+ P W
Sbjct: 954 GVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDW 991
>sp|Q99NB7|CACH1_RAT Cytoplasmic acetyl-CoA hydrolase 1 (CACH-1) (rACH) (Acyl-CoA
thioesterase 12)
Length = 556
Score = 57.4 bits (137), Expect = 5e-08
Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 5/151 (3%)
Frame = +1
Query: 37 GWSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVG--AGVMYDVLHDPDYRKVWDRGMI 210
GW I ++I+ + D VK++ K VG A V Y +L D R +WD I
Sbjct: 368 GWEITTTLEKIKIY--TLEEQDAISVKVE---KQVGSPARVAYHLLSDFTKRPLWDPHYI 422
Query: 211 KSKDICMINPNNDIGYYALRSPPPFKNRDFV---TQRSWLQTPTEYIIFNHSVFHKEMPP 381
+ I ++ ++ I Y K +DFV +QR L+ YI+ SV +PP
Sbjct: 423 SCEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSQRKPLKDDNTYIVALMSVVLPSVPP 482
Query: 382 QKSFIRAISQLTGYLIRPLENNGCVLTYVAQ 474
+IR+ G+LI+P++++ C + Y+ Q
Sbjct: 483 SPQYIRSQVICAGFLIQPVDSSSCTVAYLNQ 513
>sp|Q8R1R3|STAR7_MOUSE StAR-related lipid transfer protein 7 (StARD7) (START
domain-containing protein 7)
Length = 295
Score = 54.3 bits (129), Expect = 4e-07
Identities = 42/189 (22%), Positives = 80/189 (42%), Gaps = 6/189 (3%)
Frame = +1
Query: 25 DNHDGWSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRG 204
D + W + ++K ++W + + ++ DV ++V D +YRK WD
Sbjct: 61 DKEEPWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDAL 120
Query: 205 MIKSKDICM-INPNNDIGYYALRSPPPFKNRDFVTQRSWL--QTPTEYIIFNHSVFHKEM 375
+IK + I +++ ++ P P +RD+V R + Q ++ + +V H +
Sbjct: 121 VIKLEVIERDAVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSV 180
Query: 376 PPQKSFIRAISQLTGYLIRP---LENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVM 546
P F+R S + +IRP + NG +P+ P + V+ P +
Sbjct: 181 PESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFL 240
Query: 547 TRLLKAALK 573
+L A LK
Sbjct: 241 EKLHMATLK 249
>sp|P53808|PPCT_MOUSE Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid
transfer protein 2) (StARD2) (START domain-containing
protein 2)
Length = 214
Score = 54.3 bits (129), Expect = 4e-07
Identities = 40/183 (21%), Positives = 73/183 (39%), Gaps = 4/183 (2%)
Frame = +1
Query: 40 WSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIKSK 219
W + V + I+ S K+ L+ ++ DV D DYRK WD+ + +
Sbjct: 30 WQLLVEASGITIYRLLDQPSGLYEYKVFGVLEGCSPALLTDVYMDLDYRKQWDQYVKELY 89
Query: 220 DICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTE----YIIFNHSVFHKEMPPQK 387
+ + + Y+ ++ P P NRD+V R + Y++ S+ + P +
Sbjct: 90 E--KESDEQMVAYWEVKYPFPLSNRDYVYTRQRRDLDVDRRKIYVVLAQSISAPQFPEKS 147
Query: 388 SFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVMTRLLKAA 567
IR I G + +P G++P+W +N A + P + ++KA
Sbjct: 148 GVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIPSWLINWAAKNGVPNFLKDMVKAC 207
Query: 568 LKY 576
Y
Sbjct: 208 QNY 210
>sp|Q9NQZ5|STAR7_HUMAN StAR-related lipid transfer protein 7 (StARD7) (START
domain-containing protein 7) (GTT1 protein)
Length = 295
Score = 53.5 bits (127), Expect = 7e-07
Identities = 41/184 (22%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Frame = +1
Query: 40 WSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIKSK 219
W + ++K ++W + + ++ DV ++V D +YRK WD +IK +
Sbjct: 66 WEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLE 125
Query: 220 DICM-INPNNDIGYYALRSPPPFKNRDFVTQRSWL--QTPTEYIIFNHSVFHKEMPPQKS 390
I + +++ ++ P P +RD+V R + Q ++ + +V H +P
Sbjct: 126 VIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNMMVLVSRAVEHPSVPESPE 185
Query: 391 FIRAISQLTGYLIRP---LENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVMTRLLK 561
F+R S + +IRP + NG +P+ P + V+ P + +L
Sbjct: 186 FVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHM 245
Query: 562 AALK 573
A LK
Sbjct: 246 ATLK 249
>sp|Q9DBK0|CACH1_MOUSE Cytoplasmic acetyl-CoA hydrolase 1 (CACH-1) (mCACH-1) (Acyl-CoA
thioesterase 12)
Length = 556
Score = 52.0 bits (123), Expect = 2e-06
Identities = 39/150 (26%), Positives = 68/150 (45%), Gaps = 4/150 (2%)
Frame = +1
Query: 37 GWSIEVNKPDLQIWCKAAPDS-DFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIK 213
GW I ++I+ D+ K+ KL + A + Y +L D R +WD I
Sbjct: 368 GWEITTTLEKIKIYTLEEQDAISVKVEKLVGS----PAHIAYHLLSDLTKRPLWDPHYIS 423
Query: 214 SKDICMINPNNDIGYYALRSPPPFKNRDFV---TQRSWLQTPTEYIIFNHSVFHKEMPPQ 384
+ I ++ ++ I Y K +DFV ++R L+ Y + SV +P
Sbjct: 424 CEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSRRKPLKDNNTYTVALRSVVLPSVPSS 483
Query: 385 KSFIRAISQLTGYLIRPLENNGCVLTYVAQ 474
+IR+ G+LI+ +++N C +TY+ Q
Sbjct: 484 PQYIRSEVICAGFLIQAVDSNSCTVTYLNQ 513
>sp|P53809|PPCT_RAT Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid
transfer protein 2) (StARD2) (START domain-containing
protein 2)
Length = 214
Score = 50.4 bits (119), Expect = 6e-06
Identities = 38/183 (20%), Positives = 72/183 (39%), Gaps = 4/183 (2%)
Frame = +1
Query: 40 WSIEVNKPDLQIWCKAAPDSDFKIVKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIKSK 219
W + V + I+ + K+ L+ ++ DV D DYRK WD+ + +
Sbjct: 30 WQLLVEASGITIYRLLDQSTGLYEYKVFGVLESCIPSLLADVYMDLDYRKKWDQYVKELY 89
Query: 220 DICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTE----YIIFNHSVFHKEMPPQK 387
+ + Y+ ++ P P NRD+V R + Y++ ++ + P +
Sbjct: 90 EKSF--DGQMVAYWEVKYPFPLSNRDYVYTRQRRDLDVDGRKIYVVLAQNISVPQFPEKS 147
Query: 388 SFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPKVMTRLLKAA 567
IR I G + +P G++P+W +N A + P + ++KA
Sbjct: 148 GVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIPSWLINWAAKNGVPSFLKDMVKAC 207
Query: 568 LKY 576
Y
Sbjct: 208 QNY 210
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,836,959
Number of Sequences: 369166
Number of extensions: 2026935
Number of successful extensions: 4759
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4595
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4745
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)