Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_F15
(878 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y365|PCTL_HUMAN PCTP-like protein (PCTP-L) (StAR-relat... 180 4e-45
sp|Q9JMD3|PCTL_MOUSE PCTP-like protein (PCTP-L) (StAR-relat... 179 7e-45
sp|Q99NB7|CACH1_RAT Cytoplasmic acetyl-CoA hydrolase 1 (CAC... 54 4e-07
sp|Q8K031|STAR8_MOUSE StAR-related lipid transfer protein 8... 53 1e-06
sp|Q92502|STAR8_HUMAN StAR-related lipid transfer protein 8... 53 1e-06
sp|P53808|PPCT_MOUSE Phosphatidylcholine transfer protein (... 52 2e-06
sp|Q63744|RHG07_RAT Rho-GTPase-activating protein 7 (Rho-ty... 50 6e-06
sp|P53809|PPCT_RAT Phosphatidylcholine transfer protein (PC... 50 1e-05
sp|Q9Y3M8|STA13_HUMAN StAR-related lipid transfer protein 1... 49 2e-05
sp|Q9UKL6|PPCT_HUMAN Phosphatidylcholine transfer protein (... 49 2e-05
>sp|Q9Y365|PCTL_HUMAN PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10)
(StARD10) (START domain-containing protein 10)
(Serologically defined colon cancer antigen 28) (Antigen
NY-CO-28)
Length = 291
Score = 180 bits (457), Expect = 4e-45
Identities = 81/160 (50%), Positives = 109/160 (68%)
Frame = +2
Query: 17 VKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKN 196
+K + DV A +YDVLHD +YRK WD +I++ DI + N D+GYY+ R P P KN
Sbjct: 68 IKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKN 127
Query: 197 RDFVTQRSWLQTPTEYIIFNHSVFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVA 376
RD +T RSWL +YII N+SV H + PP+K +RA+S TGYLI+ CV+TY+A
Sbjct: 128 RDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLA 187
Query: 377 QCDPRGKLPAWAVNKATQYVAPKVMTRLLKAALKYPAWKK 496
Q DP+G LP W VNK++Q++APK M ++ KA LKYP WK+
Sbjct: 188 QVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACLKYPEWKQ 227
Score = 37.4 bits (85), Expect = 0.055
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +1
Query: 490 EKKHNPDLKPWLYPEQLQLPRINFDHIITTPDFQDNTLDESEVTET 627
++KH P KPWL+PEQ LP + + +DES V E+
Sbjct: 226 KQKHLPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVAES 271
>sp|Q9JMD3|PCTL_MOUSE PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10)
(StARD10) (START domain-containing protein 10)
(Serologically defined colon cancer antigen 28 homolog)
Length = 291
Score = 179 bits (455), Expect = 7e-45
Identities = 80/160 (50%), Positives = 109/160 (68%)
Frame = +2
Query: 17 VKLKSNLKDVGAGVMYDVLHDPDYRKVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKN 196
+K + DV A +YDVLHD +YRK WD +I++ DI + N D+GYY+ R P P KN
Sbjct: 68 IKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKN 127
Query: 197 RDFVTQRSWLQTPTEYIIFNHSVFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVA 376
RD +T RSWL +YII N+SV H + PP+K +RA+S TGYLI+ CV+TY+A
Sbjct: 128 RDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLA 187
Query: 377 QCDPRGKLPAWAVNKATQYVAPKVMTRLLKAALKYPAWKK 496
Q DP+G LP W VNK++Q++APK M ++ KA +KYP WK+
Sbjct: 188 QVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACIKYPEWKQ 227
Score = 40.4 bits (93), Expect = 0.007
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +1
Query: 490 EKKHNPDLKPWLYPEQLQLPRINFDHIITTPDFQDNTLDESEVTET 627
++KH P KPWL+PEQ LP + + +DES VTE+
Sbjct: 226 KQKHQPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVTES 271
>sp|Q99NB7|CACH1_RAT Cytoplasmic acetyl-CoA hydrolase 1 (CACH-1) (rACH) (Acyl-CoA
thioesterase 12)
Length = 556
Score = 54.3 bits (129), Expect = 4e-07
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Frame = +2
Query: 38 KDVG--AGVMYDVLHDPDYRKVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFV- 208
K VG A V Y +L D R +WD I + I ++ ++ I Y K +DFV
Sbjct: 395 KQVGSPARVAYHLLSDFTKRPLWDPHYISCEVIDQVSEDDQIYYITCSVVNGDKPKDFVV 454
Query: 209 --TQRSWLQTPTEYIIFNHSVFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQ 379
+QR L+ YI+ SV +PP +IR+ G+LI+P++++ C + Y+ Q
Sbjct: 455 LVSQRKPLKDDNTYIVALMSVVLPSVPPSPQYIRSQVICAGFLIQPVDSSSCTVAYLNQ 513
>sp|Q8K031|STAR8_MOUSE StAR-related lipid transfer protein 8 (StARD8) (START
domain-containing protein 8)
Length = 851
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Frame = +2
Query: 50 AGVMYDVLHDPDYRKVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQ 229
A V++ VL + R +WD +++++ + + P ++ +Y S P RDFV R W
Sbjct: 702 AVVLHRVLRE---RALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRS 758
Query: 230 T-PTEYIIFNHSVFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPA 406
P + E P +S +RA+ + YL+ P LT++ + D RG+ P
Sbjct: 759 DLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPD 818
Query: 407 W 409
W
Sbjct: 819 W 819
>sp|Q92502|STAR8_HUMAN StAR-related lipid transfer protein 8 (StARD8) (START
domain-containing protein 8)
Length = 1023
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Frame = +2
Query: 50 AGVMYDVLHDPDYRKVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQ 229
A V++ VL + R +WD +++++ + + P ++ +Y S P RDFV R W
Sbjct: 874 AVVLHRVLRE---RALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRS 930
Query: 230 T-PTEYIIFNHSVFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPA 406
P + E P +S +RA+ + YL+ P LT++ + D RG+ P
Sbjct: 931 DLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPD 990
Query: 407 W 409
W
Sbjct: 991 W 991
>sp|P53808|PPCT_MOUSE Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid
transfer protein 2) (StARD2) (START domain-containing
protein 2)
Length = 214
Score = 52.4 bits (124), Expect = 2e-06
Identities = 35/153 (22%), Positives = 64/153 (41%), Gaps = 4/153 (2%)
Frame = +2
Query: 35 LKDVGAGVMYDVLHDPDYRKVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQ 214
L+ ++ DV D DYRK WD+ + + + + + Y+ ++ P P NRD+V
Sbjct: 60 LEGCSPALLTDVYMDLDYRKQWDQYVKELYE--KESDEQMVAYWEVKYPFPLSNRDYVYT 117
Query: 215 RSWLQTPTE----YIIFNHSVFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQC 382
R + Y++ S+ + P + IR I G +
Sbjct: 118 RQRRDLDVDRRKIYVVLAQSISAPQFPEKSGVIRVKQYKQSLAIESDGKKGSRVFMYYFD 177
Query: 383 DPRGKLPAWAVNKATQYVAPKVMTRLLKAALKY 481
+P G++P+W +N A + P + ++KA Y
Sbjct: 178 NPGGQIPSWLINWAAKNGVPNFLKDMVKACQNY 210
>sp|Q63744|RHG07_RAT Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein
7) (p122-RhoGAP) (Deleted in liver cancer 1 protein
homolog) (Dlc-1) (StAR-related lipid transfer protein 12)
(StARD12) (START domain-containing protein 12)
Length = 1091
Score = 50.4 bits (119), Expect = 6e-06
Identities = 36/122 (29%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Frame = +2
Query: 95 VWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSW---LQTPTEYIIFNHSV 265
+WD ++ SK I +++ +I Y S P RD+V R+W L ++F SV
Sbjct: 954 LWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLFT-SV 1012
Query: 266 FHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAWAVNKATQYVAPK 445
H P + +R L+ YLI P + LTY+ + D RG +P W A +
Sbjct: 1013 DHDRAP--VAGVRVNVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAE 1070
Query: 446 VM 451
V+
Sbjct: 1071 VV 1072
>sp|P53809|PPCT_RAT Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid
transfer protein 2) (StARD2) (START domain-containing
protein 2)
Length = 214
Score = 49.7 bits (117), Expect = 1e-05
Identities = 33/146 (22%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 56 VMYDVLHDPDYRKVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTP 235
++ DV D DYRK WD+ + + + + Y+ ++ P P NRD+V R
Sbjct: 67 LLADVYMDLDYRKKWDQYVKELYEKSF--DGQMVAYWEVKYPFPLSNRDYVYTRQRRDLD 124
Query: 236 TE----YIIFNHSVFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLP 403
+ Y++ ++ + P + IR I G + +P G++P
Sbjct: 125 VDGRKIYVVLAQNISVPQFPEKSGVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIP 184
Query: 404 AWAVNKATQYVAPKVMTRLLKAALKY 481
+W +N A + P + ++KA Y
Sbjct: 185 SWLINWAAKNGVPSFLKDMVKACQNY 210
>sp|Q9Y3M8|STA13_HUMAN StAR-related lipid transfer protein 13 (StARD13) (START
domain-containing protein 13) (46H23.2)
Length = 995
Score = 48.9 bits (115), Expect = 2e-05
Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 2/109 (1%)
Frame = +2
Query: 89 RKVWDRGMIKSKDICMINPNNDIGYYALRSPPPFKNRDFVTQRSWLQTPTEYI--IFNHS 262
R +WD ++ K + ++ +I Y L S P +RDFV R+W + + + + S
Sbjct: 856 RHLWDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLS 915
Query: 263 VFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQCDPRGKLPAW 409
V H+E +RA+ + YLI P + LT++ + D +G P W
Sbjct: 916 VEHEE-AQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEW 963
>sp|Q9UKL6|PPCT_HUMAN Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid
transfer protein 2) (StARD2) (START domain-containing
protein 2)
Length = 214
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 5/154 (3%)
Frame = +2
Query: 35 LKDVGAGVMYDVLHDPDYRKVWDRGMIKSKDICMINPNND-IGYYALRSPPPFKNRDFVT 211
L+D ++ D+ D DYRK WD+ + K++ N + + Y+ ++ P P NRD+V
Sbjct: 60 LEDCSPTLLADIYMDSDYRKQWDQYV---KELYEQECNGETVVYWEVKYPFPMSNRDYVY 116
Query: 212 QRSWLQTPTE----YIIFNHSVFHKEMPPQKSFIRAISQLTGYLIRPLENNGCVLTYVAQ 379
R E ++I S ++ + IR I G +
Sbjct: 117 LRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAIESDGKKGSKVFMYYF 176
Query: 380 CDPRGKLPAWAVNKATQYVAPKVMTRLLKAALKY 481
+P G++P+W +N A + P + + +A Y
Sbjct: 177 DNPGGQIPSWLINWAAKNGVPNFLKDMARACQNY 210
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,415,223
Number of Sequences: 369166
Number of extensions: 2219453
Number of successful extensions: 5067
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4877
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5055
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8742211660
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)