Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00923 (304 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-relat... 36 0.032 sp|P56677|ST14_MOUSE Suppressor of tumorigenicity 14 (Epithin) 34 0.12 sp|Q00996|CD59_SHV21 Surface glycoprotein CD59 homolog prec... 33 0.16 sp|P23502|SL17_ENTHI 170 kDa surface lectin precursor 32 0.35 sp|Q9Y5Y6|ST14_HUMAN Suppressor of tumorigenicity 14 (Matri... 32 0.46 sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-rela... 31 0.78 sp|O75094|SLIT3_HUMAN Slit homolog 3 protein precursor (Sli... 30 2.3 sp|Q8NEZ4|MLL3_HUMAN Myeloid/lymphoid or mixed-lineage leuk... 30 2.3 sp|Q8BRH4|MLL3_MOUSE Myeloid/lymphoid or mixed-lineage leuk... 30 2.3 sp|P83107|BOP1_BOVIN BOP-1 protein precursor 30 2.3
>sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91) Length = 4544 Score = 35.8 bits (81), Expect = 0.032 Identities = 22/68 (32%), Positives = 29/68 (42%) Frame = +3 Query: 51 ALKCYECDHCEGKAGSPSKDSCDYCLEEAKKDGINRRCGKGGCLSIGNLKCCKNKDLCND 230 +L C HC+ K S + YC K R+C G C+S N+ C D C D Sbjct: 2541 SLTCDGVPHCKDK----SDEKPSYCNSRRCKKTF-RQCSNGRCVS--NMLWCNGADDCGD 2593 Query: 231 GK*NLDCN 254 G + CN Sbjct: 2594 GSDEIPCN 2601
>sp|P56677|ST14_MOUSE Suppressor of tumorigenicity 14 (Epithin) Length = 855 Score = 33.9 bits (76), Expect = 0.12 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 8/58 (13%) Frame = +3 Query: 105 KDSCDYCLEEAKKDGIN--------RRCGKGGCLSIGNLKCCKNKDLCNDGK*NLDCN 254 KD+C +EA D +N RC G CLS GN +C D C+DG +C+ Sbjct: 547 KDNCGDGSDEASCDSVNVVSCTKYTYRCQNGLCLSKGNPECDGKTD-CSDGSDEKNCD 603
>sp|Q00996|CD59_SHV21 Surface glycoprotein CD59 homolog precursor Length = 121 Score = 33.5 bits (75), Expect = 0.16 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 13/91 (14%) Frame = +3 Query: 3 LLFVVSVVLTIISEYEALKCYECDH--CEGKAGSPSKDSCDYCLEEAKKDGINRRCGK-- 170 +LF + + +L+CY C H + + + D CL G+ RC K Sbjct: 3 ILFTLVLTFVFCKPIHSLQCYNCSHSTMQCTTSTSCTSNLDSCLIAKAGSGVYYRCWKFD 62 Query: 171 -------GGCLSIGNLK--CCKNKDLCNDGK 236 LS LK CCK K+LCN K Sbjct: 63 DCSFKRISNQLSETQLKYHCCK-KNLCNVNK 92
>sp|P23502|SL17_ENTHI 170 kDa surface lectin precursor Length = 1285 Score = 32.3 bits (72), Expect = 0.35 Identities = 21/82 (25%), Positives = 29/82 (35%), Gaps = 16/82 (19%) Frame = +3 Query: 66 ECDHCEGKAGSPSKDSCDYCLEEAKKDGINRRCGKGGCLSIGNLKC----CKNKDL---- 221 EC C + D C EE K G+ +C C+ N C CK +++ Sbjct: 914 ECKTCSLTETKEKVEEIDLCAEETKNGGVPFKCKNNNCIIDPNFDCQPIECKIQEIVITE 973 Query: 222 --------CNDGK*NLDCNFNN 263 C DG C+ NN Sbjct: 974 KDGIKTTTCKDGT-KTTCDTNN 994
>sp|Q9Y5Y6|ST14_HUMAN Suppressor of tumorigenicity 14 (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor associated differentially-expressed gene-15 protein) Length = 855 Score = 32.0 bits (71), Expect = 0.46 Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 8/58 (13%) Frame = +3 Query: 105 KDSCDYCLEEAKKDGIN--------RRCGKGGCLSIGNLKCCKNKDLCNDGK*NLDCN 254 KD C +EA +N RC G CLS GN + C K+ C+DG DC+ Sbjct: 547 KDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPE-CDGKEDCSDGSDEKDCD 603
>sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-related protein 1B precursor (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT) Length = 4599 Score = 31.2 bits (69), Expect = 0.78 Identities = 14/33 (42%), Positives = 17/33 (51%) Frame = +3 Query: 162 CGKGGCLSIGNLKCCKNKDLCNDGK*NLDCNFN 260 C G C+ G L C NKD C DG +C+ N Sbjct: 2898 CKNGRCIPSGGL--CDNKDDCGDGSDERNCHIN 2928
>sp|O75094|SLIT3_HUMAN Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5) Length = 1523 Score = 29.6 bits (65), Expect = 2.3 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 16/73 (21%) Frame = +3 Query: 60 CYECDHCE-GKAGSPSKDS--CD--------YCLEEAKKDGINRRCGKGGCLSIGNLKCC 206 C C C+ G S KDS C+ C +EA+ + RC G C++ G C Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMC 1391 Query: 207 K-----NKDLCND 230 K DLC++ Sbjct: 1392 KCAEGYGGDLCDN 1404
>sp|Q8NEZ4|MLL3_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein) Length = 4911 Score = 29.6 bits (65), Expect = 2.3 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 11/52 (21%) Frame = +3 Query: 9 FVVSVVLTIISEYEALKCYECDHCE--GKAGSPSK----DSCD-----YCLE 131 + VS+ +T + + +C EC CE GKA P + D CD YCL+ Sbjct: 987 YCVSIKITKVVLSKGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLD 1038
>sp|Q8BRH4|MLL3_MOUSE Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) Length = 4903 Score = 29.6 bits (65), Expect = 2.3 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 11/52 (21%) Frame = +3 Query: 9 FVVSVVLTIISEYEALKCYECDHCE--GKAGSPSK----DSCD-----YCLE 131 + VS+ +T + + +C EC CE GKA P + D CD YCL+ Sbjct: 980 YCVSIKITKVVLSKGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLD 1031
>sp|P83107|BOP1_BOVIN BOP-1 protein precursor Length = 100 Score = 29.6 bits (65), Expect = 2.3 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 20/95 (21%) Frame = +3 Query: 3 LLFVVSVVLTIISEYEALKCYECDHCEGKAGSPSKDSCDYCLEEAKKDGINRRCGKGGCL 182 LL ++ V+ +++ +AL+C++C+ A + C + + RR + G L Sbjct: 6 LLLLLVVLSSLLGLPQALECFQCNRV--NASGVCETGGSTCQTQGSQQCFLRRIFENGTL 63 Query: 183 SIGN--------------------LKCCKNKDLCN 227 S G+ KCC + LCN Sbjct: 64 SYGHQGCSQLCIPMKLFNPSVIVEYKCCHDSPLCN 98
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,209,815 Number of Sequences: 369166 Number of extensions: 458855 Number of successful extensions: 1414 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1327 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1412 length of database: 68,354,980 effective HSP length: 69 effective length of database: 55,608,265 effective search space used: 1723856215 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)