Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_C23
(273 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23502|SL17_ENTHI 170 kDa surface lectin precursor 38 0.008
sp|P32022|GIL1_ENTHI Galactose-inhibitable lectin 170 kDa s... 35 0.071
sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-relat... 33 0.21
sp|P56677|ST14_MOUSE Suppressor of tumorigenicity 14 (Epithin) 33 0.27
sp|Q9Y5Y6|ST14_HUMAN Suppressor of tumorigenicity 14 (Matri... 32 0.60
sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-rela... 31 0.78
sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexi... 30 2.3
sp|O75094|SLIT3_HUMAN Slit homolog 3 protein precursor (Sli... 29 3.0
sp|O88280|SLIT3_RAT Slit homolog 3 protein precursor (Slit-... 28 5.1
sp|P98155|VLDLR_HUMAN Very low-density lipoprotein receptor... 28 6.6
>sp|P23502|SL17_ENTHI 170 kDa surface lectin precursor
Length = 1285
Score = 37.7 bits (86), Expect = 0.008
Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 16/82 (19%)
Frame = +2
Query: 35 ECDHCAGKAGSPSKDSCDYCLEEAKNGGINRRCGKGGCLSIGNLKC----CKNKDL---- 190
EC C+ + D C EE KNGG+ +C C+ N C CK +++
Sbjct: 914 ECKTCSLTETKEKVEEIDLCAEETKNGGVPFKCKNNNCIIDPNFDCQPIECKIQEIVITE 973
Query: 191 --------CNDGE*NLDCNFNN 232
C DG C+ NN
Sbjct: 974 KDGIKTTTCKDGT-KTTCDTNN 994
>sp|P32022|GIL1_ENTHI Galactose-inhibitable lectin 170 kDa subunit
Length = 1276
Score = 34.7 bits (78), Expect = 0.071
Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
Frame = +2
Query: 35 ECDHCAGKAGSPSKDSCDYCLEEAKNGGINRRCGKGGCLSIGNLKC----CKNKDL 190
EC C+ D C EE KNGG+ +C C+ N C CK +++
Sbjct: 906 ECKTCSLIETREKVQEVDLCAEETKNGGVPFKCKNNNCIIDPNFDCQPIECKIQEI 961
>sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E
receptor) (APOER) (CD91)
Length = 4544
Score = 33.1 bits (74), Expect = 0.21
Identities = 21/68 (30%), Positives = 28/68 (41%)
Frame = +2
Query: 20 ALKCYECDHCAGKAGSPSKDSCDYCLEEAKNGGINRRCGKGGCLSIGNLKCCKNKDLCND 199
+L C HC K S + YC + R+C G C+S N+ C D C D
Sbjct: 2541 SLTCDGVPHCKDK----SDEKPSYC-NSRRCKKTFRQCSNGRCVS--NMLWCNGADDCGD 2593
Query: 200 GE*NLDCN 223
G + CN
Sbjct: 2594 GSDEIPCN 2601
>sp|P56677|ST14_MOUSE Suppressor of tumorigenicity 14 (Epithin)
Length = 855
Score = 32.7 bits (73), Expect = 0.27
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 10/63 (15%)
Frame = +2
Query: 74 KDSCDYCLEEAKNGGIN--------RRCGKGGCLSIGNLKCCKNKDLCNDG--E*NLDCN 223
KD+C +EA +N RC G CLS GN +C D C+DG E N DC
Sbjct: 547 KDNCGDGSDEASCDSVNVVSCTKYTYRCQNGLCLSKGNPECDGKTD-CSDGSDEKNCDCG 605
Query: 224 FNN 232
+
Sbjct: 606 LRS 608
>sp|Q9Y5Y6|ST14_HUMAN Suppressor of tumorigenicity 14 (Matriptase) (Membrane-type serine
protease 1) (MT-SP1) (Prostamin) (Serine protease
TADG-15) (Tumor associated differentially-expressed
gene-15 protein)
Length = 855
Score = 31.6 bits (70), Expect = 0.60
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 8/58 (13%)
Frame = +2
Query: 74 KDSCDYCLEEAKNGGIN--------RRCGKGGCLSIGNLKCCKNKDLCNDGE*NLDCN 223
KD C +EA +N RC G CLS GN + C K+ C+DG DC+
Sbjct: 547 KDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPE-CDGKEDCSDGSDEKDCD 603
>sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-related protein 1B precursor
(Low-density lipoprotein receptor-related protein-deleted
in tumor) (LRP-DIT)
Length = 4599
Score = 31.2 bits (69), Expect = 0.78
Identities = 14/33 (42%), Positives = 17/33 (51%)
Frame = +2
Query: 131 CGKGGCLSIGNLKCCKNKDLCNDGE*NLDCNFN 229
C G C+ G L C NKD C DG +C+ N
Sbjct: 2898 CKNGRCIPSGGL--CDNKDDCGDGSDERNCHIN 2928
>sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexin type 6 precursor (Paired
basic amino acid cleaving enzyme 4)
(Subtilisin/kexin-like protease PACE4) (Subtilisin-like
proprotein convertase 4) (SPC4)
Length = 969
Score = 29.6 bits (65), Expect = 2.3
Identities = 12/32 (37%), Positives = 17/32 (53%)
Frame = +2
Query: 17 EALKCYECDHCAGKAGSPSKDSCDYCLEEAKN 112
E ++C EC H G P ++ C +C AKN
Sbjct: 841 ELIRCGECHHTCGTCVGPGREECIHC---AKN 869
>sp|O75094|SLIT3_HUMAN Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth
factor-like domains 5)
Length = 1523
Score = 29.3 bits (64), Expect = 3.0
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 15/72 (20%)
Frame = +2
Query: 29 CYECDHCAGKAGSPSKDS--CD--------YCLEEAKNGGINRRCGKGGCLSIGNLKCCK 178
C C H G S KDS C+ C +EA++ + RC G C++ G CK
Sbjct: 1335 CTVCKH--GLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCK 1392
Query: 179 -----NKDLCND 199
DLC++
Sbjct: 1393 CAEGYGGDLCDN 1404
>sp|O88280|SLIT3_RAT Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth
factor-like domains 5)
Length = 1523
Score = 28.5 bits (62), Expect = 5.1
Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 11/61 (18%)
Frame = +2
Query: 29 CYECDHCA-GKAGSPSKDS--CD--------YCLEEAKNGGINRRCGKGGCLSIGNLKCC 175
C C C G S KDS C+ C +EA++ + C G C++ GN C
Sbjct: 1332 CKSCTVCRHGLCRSVEKDSVVCECHPGWTGPLCDQEAQDPCLGHSCSHGTCVATGNSYVC 1391
Query: 176 K 178
K
Sbjct: 1392 K 1392
>sp|P98155|VLDLR_HUMAN Very low-density lipoprotein receptor precursor (VLDL receptor)
Length = 873
Score = 28.1 bits (61), Expect = 6.6
Identities = 17/54 (31%), Positives = 24/54 (44%), Gaps = 5/54 (9%)
Frame = +2
Query: 74 KDSCDYCLEEAKNGGINRR-----CGKGGCLSIGNLKCCKNKDLCNDGE*NLDC 220
++ CD +E G I C G C+S + C +D C+DG LDC
Sbjct: 137 ENDCDSGEDEENCGNITCSPDEFTCSSGRCISRNFV--CNGQDDCSDGSDELDC 188
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,206,283
Number of Sequences: 369166
Number of extensions: 308511
Number of successful extensions: 961
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 918
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 960
length of database: 68,354,980
effective HSP length: 60
effective length of database: 57,270,880
effective search space used: 1718126400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)