DrC_00917
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00917 (909 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane... 75 3e-13 sp|Q80WR1|TSN18_MOUSE Tetraspanin-18 (Tspan-18) 74 4e-13 sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane... 74 4e-13 sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen ... 73 1e-12 sp|O60635|TSN1_HUMAN Tetraspanin-1 (Tspan-1) (Tetraspan NET... 72 2e-12 sp|P24485|CD53_RAT Leukocyte surface antigen CD53 (Cell sur... 72 2e-12 sp|Q61451|CD53_MOUSE Leukocyte surface antigen CD53 (Cell s... 72 2e-12 sp|Q5RC27|TSN1_PONPY Tetraspanin-1 (Tspan-1) 71 4e-12 sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen... 71 5e-12 sp|P19397|CD53_HUMAN Leukocyte surface antigen CD53 (Cell s... 70 6e-12
>sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8) (Tetraspanin TM4-A) Length = 253 Score = 75.1 bits (183), Expect = 3e-13 Identities = 52/194 (26%), Positives = 93/194 (47%), Gaps = 8/194 (4%) Frame = +1 Query: 187 VLVAAGILIFLTAIFGCIGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAV 366 V++A G L+F+ + GC TI+ESRC + F L ++Y+ + E+ V Sbjct: 56 VIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEV 115 Query: 367 TTHLQKEFTNKYGVD-EPYTRLWDEFQPEHKCCGIDSGADYKSTKWYNSPNQDFHRDGEV 543 +QK + G + + +R D Q + CCGI + +D+++T W+ ++ V Sbjct: 116 DRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKET-----KNQSV 170 Query: 544 PLSCCTMHGDGHLNVTQCHKS--RPEDQGPYIYNTGCWEIMQKSV-SLVLH--WSSI--A 702 PLSCC + C+ S P D +Y GC ++ K + +++H W+++ A Sbjct: 171 PLSCC------RETASNCNGSLAHPSD----LYAEGCEALVVKKLQEIMMHVIWAALAFA 220 Query: 703 VFILCGILLFIVIL 744 L G+L ++L Sbjct: 221 AIQLLGMLCACIVL 234
>sp|Q80WR1|TSN18_MOUSE Tetraspanin-18 (Tspan-18) Length = 248 Score = 74.3 bits (181), Expect = 4e-13 Identities = 51/237 (21%), Positives = 97/237 (40%), Gaps = 5/237 (2%) Frame = +1 Query: 61 IFSYSFLVLLSILCG-GFGGWLISQEHWTILLFGTQTIQSMG-WVLVAAGILIFLTAIFG 234 +F ++F V L C G G W++ + T + + G ++++A G L+FL G Sbjct: 13 MFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYIVLAMGGLLFLLGFLG 72 Query: 235 CIGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAVTTHLQKEFTNKYGVD- 411 C G ++E+RC ++ F + L FI++ E KE T Y D Sbjct: 73 CCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFR---EHLTREFFTKELTKHYQGDN 129 Query: 412 --EPYTRLWDEFQPEHKCCGIDSGADYKSTKWYNSPNQDFHRDGEVPLSCCTMHGDGHLN 585 + ++ W+ CCG++ D+K + D EVP +CC Sbjct: 130 DTDVFSATWNSVMITFGCCGVNGPEDFKLASVFRLLTLDTE---EVPKACCRREPQTRDG 186 Query: 586 VTQCHKSRPEDQGPYIYNTGCWEIMQKSVSLVLHWSSIAVFILCGILLFIVILSFVM 756 V + + P+I GC+ ++ + ++ + + I LF+++ + + Sbjct: 187 VVLSREECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVFAMCL 243
>sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8) (Tetraspanin TM4-A) (OSP-associated protein 1) (OAP-1) Length = 253 Score = 74.3 bits (181), Expect = 4e-13 Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 8/194 (4%) Frame = +1 Query: 187 VLVAAGILIFLTAIFGCIGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAV 366 V++A G L+F+ + GC TI+ESRC + F L ++Y+ + E+ V Sbjct: 56 VIIAVGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEV 115 Query: 367 TTHLQKEFTNKYGVD-EPYTRLWDEFQPEHKCCGIDSGADYKSTKWYNSPNQDFHRDGEV 543 +QK + G + + +R D Q + CCGI + +D+++T W+ ++ V Sbjct: 116 DRSIQKVYKTYNGTNSDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKET-----KNQSV 170 Query: 544 PLSCCTMHGDGHLNVTQCHKS--RPEDQGPYIYNTGCWEIMQKSVSLVLH---WSSI--A 702 PLSCC C+ S P D +Y GC ++ K + +L W+++ A Sbjct: 171 PLSCC------RETAKSCNGSLANPSD----LYAEGCEALVVKKLQEILMHVIWAALAFA 220 Query: 703 VFILCGILLFIVIL 744 L G+L ++L Sbjct: 221 AIQLLGMLCACIVL 234
>sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen 3 (CD151 antigen) Length = 253 Score = 72.8 bits (177), Expect = 1e-12 Identities = 43/171 (25%), Positives = 81/171 (47%), Gaps = 5/171 (2%) Frame = +1 Query: 61 IFSYS---FLVLLSILCGGFGGWLISQEHWTILLFGTQTIQSMGWVLVAAGILIFLTAIF 231 +F+Y+ +L L+++ G W ++ + I L + T + ++LV AG+++ +T + Sbjct: 20 LFTYNCCFWLAGLAVMAVGI--WTLALKSDYISLLASSTYLATAYILVVAGVVVMVTGVL 77 Query: 232 GCIGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAVTTHLQKEFTNKY--G 405 GC T KE R + ++ +G L ++Y +Q + + +L+ +Y Sbjct: 78 GCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKDTMIKRYHQS 137 Query: 406 VDEPYTRLWDEFQPEHKCCGIDSGADYKSTKWYNSPNQDFHRDGEVPLSCC 558 E T D+ Q E CCG ++ D++ ++W S D VP SCC Sbjct: 138 GHEGVTNAVDKLQQEFHCCGSNNSRDWRDSEWIRSGEAD---SRVVPDSCC 185
>sp|O60635|TSN1_HUMAN Tetraspanin-1 (Tspan-1) (Tetraspan NET-1) (Tetraspanin TM4-C) Length = 241 Score = 72.4 bits (176), Expect = 2e-12 Identities = 47/188 (25%), Positives = 77/188 (40%), Gaps = 9/188 (4%) Frame = +1 Query: 85 LLSILCGG----FGGWLISQEHWTILLFGTQTIQSM-----GWVLVAAGILIFLTAIFGC 237 LL LCG G W+ + +FG + +M G+ L+AAG+++F GC Sbjct: 16 LLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVVFALGFLGC 75 Query: 238 IGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAVTTHLQKEFTNKYGVDEP 417 G ES+C ++ F + + +Y AE +T + YG E Sbjct: 76 YGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQED 135 Query: 418 YTRLWDEFQPEHKCCGIDSGADYKSTKWYNSPNQDFHRDGEVPLSCCTMHGDGHLNVTQC 597 +T++W+ KCCG + D++ + + F + P CC + N T C Sbjct: 136 FTQVWNTTMKGLKCCGFTNYTDFEDSPY-------FKENSAFPPFCCNDNVTNTANET-C 187 Query: 598 HKSRPEDQ 621 K + DQ Sbjct: 188 TKQKAHDQ 195
>sp|P24485|CD53_RAT Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) (Leukocyte antigen MRC OX-44) Length = 219 Score = 72.4 bits (176), Expect = 2e-12 Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 3/155 (1%) Frame = +1 Query: 37 MCSLKSIN--IFSYSFLVLLSILCG-GFGGWLISQEHWTILLFGTQTIQSMGWVLVAAGI 207 M SLK + +F ++FL + C GFG L+ Q + IL F ++G VLV G Sbjct: 3 MSSLKLLKYVLFFFNFLFWVCGCCILGFGIHLLVQNTYGIL-FRNLPFLTLGNVLVIVGS 61 Query: 208 LIFLTAIFGCIGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAVTTHLQKE 387 +I + A GC+G+IKE++C ++ F LLF+Y+K+ + V L Sbjct: 62 IIMVVAFLGCMGSIKENKCLLMSFFVLLLLILLAEVTLAILLFVYEKKINTLVAEGLNDS 121 Query: 388 FTNKYGVDEPYTRLWDEFQPEHKCCGIDSGADYKS 492 + Y D WD Q + +CCG++ +D+ S Sbjct: 122 IQH-YHSDNSTRMAWDFIQSQLQCCGVNGSSDWIS 155
>sp|Q61451|CD53_MOUSE Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) Length = 219 Score = 72.4 bits (176), Expect = 2e-12 Identities = 44/156 (28%), Positives = 76/156 (48%), Gaps = 4/156 (2%) Frame = +1 Query: 37 MCSLKSINIFSYSFLVLLSILCG----GFGGWLISQEHWTILLFGTQTIQSMGWVLVAAG 204 M SLK + + F +L + CG GFG + + Q + +L F ++G +LV G Sbjct: 3 MSSLKLLKYVLFIFNLLFWV-CGCCILGFGIYFLVQNTYGVL-FRNLPFLTLGNILVIVG 60 Query: 205 ILIFLTAIFGCIGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAVTTHLQK 384 +I + A GC+G+IKE++C ++ F LLF+Y+++ + V L Sbjct: 61 SIIMVVAFLGCMGSIKENKCLLMSFFVLLLIILLAEVTIAILLFVYEQKLNTLVAEGLND 120 Query: 385 EFTNKYGVDEPYTRLWDEFQPEHKCCGIDSGADYKS 492 + Y D + WD Q + +CCG++ +D+ S Sbjct: 121 SIQH-YHSDNSTMKAWDFIQTQLQCCGVNGSSDWTS 155
>sp|Q5RC27|TSN1_PONPY Tetraspanin-1 (Tspan-1) Length = 241 Score = 71.2 bits (173), Expect = 4e-12 Identities = 50/188 (26%), Positives = 78/188 (41%), Gaps = 9/188 (4%) Frame = +1 Query: 85 LLSILCGG----FGGWLISQEHWTILLFGTQTIQSM-----GWVLVAAGILIFLTAIFGC 237 LL LCG G W+ + +FG + +M G+ L+AAG+++F GC Sbjct: 16 LLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVVFALGFLGC 75 Query: 238 IGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAVTTHLQKEFTNKYGVDEP 417 G ES+C ++ F + + +Y AE +T + YG E Sbjct: 76 YGAKTESKCALMTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQED 135 Query: 418 YTRLWDEFQPEHKCCGIDSGADYKSTKWYNSPNQDFHRDGEVPLSCCTMHGDGHLNVTQC 597 +T++W+ KCCG + D++ + Y N F P CC + N T C Sbjct: 136 FTQVWNTTMKGLKCCGFTNYTDFEDSP-YLKENHAF------PPFCCNDNITNTANDT-C 187 Query: 598 HKSRPEDQ 621 K + EDQ Sbjct: 188 TKQKAEDQ 195
>sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane glycoprotein SFA-1) (CD151 antigen) Length = 253 Score = 70.9 bits (172), Expect = 5e-12 Identities = 42/171 (24%), Positives = 81/171 (47%), Gaps = 5/171 (2%) Frame = +1 Query: 61 IFSYS---FLVLLSILCGGFGGWLISQEHWTILLFGTQTIQSMGWVLVAAGILIFLTAIF 231 +F+Y+ +L L+++ G W ++ + I L + T + ++LV AG+++ +T + Sbjct: 20 LFTYNCCFWLAGLAVMAVGI--WTLALKSDYISLLASSTYLATAYILVVAGVVVMVTGVL 77 Query: 232 GCIGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAVTTHLQKEFTNKY--G 405 GC T KE R + ++ +G L ++Y +Q + + +L+ +Y Sbjct: 78 GCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQQLNTELKENLKDTMVKRYHQS 137 Query: 406 VDEPYTRLWDEFQPEHKCCGIDSGADYKSTKWYNSPNQDFHRDGEVPLSCC 558 E + D+ Q E CCG ++ D++ ++W S D VP SCC Sbjct: 138 GHEGVSSAVDKLQQEFHCCGSNNSQDWQDSEWIRSGEAD---SRVVPDSCC 185
>sp|P19397|CD53_HUMAN Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) (Tetraspanin-25) (Tspan-25) Length = 219 Score = 70.5 bits (171), Expect = 6e-12 Identities = 45/156 (28%), Positives = 76/156 (48%), Gaps = 4/156 (2%) Frame = +1 Query: 37 MCSLKSINIFSYSFLVLLSILCG----GFGGWLISQEHWTILLFGTQTIQSMGWVLVAAG 204 M SLK + + F LL +CG GFG +L+ ++ +L ++ ++G V V G Sbjct: 3 MSSLKLLKYVLF-FFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSL-TLGNVFVIVG 60 Query: 205 ILIFLTAIFGCIGTIKESRCFIIMFXXXXXXXXXXXXXSGTLLFIYKKQAESAVTTHLQK 384 +I + A GC+G+IKE++C ++ F LLF+Y+++ V L Sbjct: 61 SIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGL-T 119 Query: 385 EFTNKYGVDEPYTRLWDEFQPEHKCCGIDSGADYKS 492 + ++Y D WD Q +CCGI+ +D+ S Sbjct: 120 DSIHRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTS 155
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,037,916
Number of Sequences: 369166
Number of extensions: 2179515
Number of successful extensions: 5826
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5582
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5797
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9222552960
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
