Planaria EST Database

DrC_00879

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00879
         (1260 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O35490|BHMT_MOUSE  Betaine--homocysteine S-methyltransferase   533   e-151
sp|Q93088|BHMT_HUMAN  Betaine--homocysteine S-methyltransferase   532   e-151
sp|O09171|BHMT_RAT  Betaine--homocysteine S-methyltransferase     519   e-147
sp|Q95332|BHMT_PIG  Betaine--homocysteine S-methyltransferase     366   e-101
sp|Q9SDL7|HMT1_ARATH  Homocysteine S-methyltransferase 1 (S-...    66   2e-10
sp|Q55786|METH_SYNY3  Methionine synthase (5-methyltetrahydr...    58   5e-08
sp|Q9FUM8|HMT3_MAIZE  Homocysteine S-methyltransferase 3 (S-...    57   1e-07
sp|Q9FUM9|HMT2_MAIZE  Homocysteine S-methyltransferase 2 (S-...    54   1e-06
sp|Q9M1W4|HMT2_ARATH  Homocysteine S-methyltransferase 2 (S-...    52   3e-06
sp|Q99707|METH_HUMAN  Methionine synthase (5-methyltetrahydr...    48   7e-05

>sp|O35490|BHMT_MOUSE Betaine--homocysteine S-methyltransferase
          Length = 407

 Score =  533 bits (1372), Expect = e-151
 Identities = 252/384 (65%), Positives = 298/384 (77%)
 Frame = +1

Query: 1    GEVIIGDGGFVFQLEKRGYVKAGPWTPEAAVEHPEAVIQLHREFLRAGSDVMQAFTFYAS 180
            GEV+IGDGGFVF LEKRGYVKAGPWTPEAAVEHPEAV QLHREFLRAGS+VMQ FTFYAS
Sbjct: 20   GEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYAS 79

Query: 181  DDKLENRGNEAASKYGGSNINRKACQLAKQVASEGQNILTLGGVSQTPSYLTGVGKAETQ 360
            +DKLENRGN  A K  G  +N  AC +A+QVA EG + L  GGVSQTPSYL+   + E +
Sbjct: 80   EDKLENRGNYVAEKISGQKVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSEVEVK 138

Query: 361  NIFRKQFTVFKEEQVDFLLCEYFEHVEEAEWAVETAKEFNMPVACSLCIGPEGDMKNVPT 540
             IFR+Q  VF ++ VDFL+ EYFEHVEEA WAVE  K    PVA ++CIGPEGD+  VP 
Sbjct: 139  KIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDLHGVPP 198

Query: 541  GECAVRLVKAGADIVGINCHHDPFIVLKAMKIMISAVKAAGLKAHFMIQPLGYMTPDASK 720
            GECAVRLVKAGA IVG+NCH DP + L+ +K+M   ++AA LKA+ M QPL Y TPD  K
Sbjct: 199  GECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQPLAYHTPDCGK 258

Query: 721  QGFIDLPEFPFALEPRICTRFDMQKYAREAYEAGIRYIGGCCGFEAYHIRAVAEELAKER 900
            QGFIDLPEFPF LEPR+ TR+D+QKYAREAY  G+RYIGGCCGFE YHIRA+AEELA ER
Sbjct: 259  QGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPER 318

Query: 901  GRFPAGSEKHEPWGEGLKMHTKPWVRARAKREYWEKLCPCTGRPYSASLAVPDQWGVTAG 1080
            G  P  SEKH  WG GL MHTKPW+RARA++EYW+ L   +GRPY+ S++ PD WGVT G
Sbjct: 319  GFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASGRPYNPSMSRPDAWGVTKG 378

Query: 1081 HEELKQQSAKTDDKEIEDLYKQLK 1152
              EL QQ   T ++++ +L+++ K
Sbjct: 379  AAELMQQKEATTEQQLRELFEKQK 402

>sp|Q93088|BHMT_HUMAN Betaine--homocysteine S-methyltransferase
          Length = 406

 Score =  532 bits (1371), Expect = e-151
 Identities = 252/384 (65%), Positives = 298/384 (77%)
 Frame = +1

Query: 1    GEVIIGDGGFVFQLEKRGYVKAGPWTPEAAVEHPEAVIQLHREFLRAGSDVMQAFTFYAS 180
            GE++IGDGGFVF LEKRGYVKAGPWTPEAAVEHPEAV QLHREFLRAGS+VMQ FTFYAS
Sbjct: 20   GEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYAS 79

Query: 181  DDKLENRGNEAASKYGGSNINRKACQLAKQVASEGQNILTLGGVSQTPSYLTGVGKAETQ 360
            +DKLENRGN    K  G  +N  AC +A+QVA EG + L  GGVSQTPSYL+   + E +
Sbjct: 80   EDKLENRGNYVLEKISGQEVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSETEVK 138

Query: 361  NIFRKQFTVFKEEQVDFLLCEYFEHVEEAEWAVETAKEFNMPVACSLCIGPEGDMKNVPT 540
             +F +Q  VF ++ VDFL+ EYFEHVEEA WAVET      PVA ++CIGPEGD+  VP 
Sbjct: 139  KVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPP 198

Query: 541  GECAVRLVKAGADIVGINCHHDPFIVLKAMKIMISAVKAAGLKAHFMIQPLGYMTPDASK 720
            GECAVRLVKAGA I+G+NCH DP I LK +K+M   ++AA LKAH M QPL Y TPD +K
Sbjct: 199  GECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNK 258

Query: 721  QGFIDLPEFPFALEPRICTRFDMQKYAREAYEAGIRYIGGCCGFEAYHIRAVAEELAKER 900
            QGFIDLPEFPF LEPR+ TR+D+QKYAREAY  G+RYIGGCCGFE YHIRA+AEELA ER
Sbjct: 259  QGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPER 318

Query: 901  GRFPAGSEKHEPWGEGLKMHTKPWVRARAKREYWEKLCPCTGRPYSASLAVPDQWGVTAG 1080
            G  P  SEKH  WG GL MHTKPWVRARA++EYWE L   +GRPY+ S++ PD WGVT G
Sbjct: 319  GFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKG 378

Query: 1081 HEELKQQSAKTDDKEIEDLYKQLK 1152
              EL QQ   T ++++++L+++ K
Sbjct: 379  TAELMQQKEATTEQQLKELFEKQK 402

>sp|O09171|BHMT_RAT Betaine--homocysteine S-methyltransferase
          Length = 407

 Score =  519 bits (1336), Expect = e-147
 Identities = 247/384 (64%), Positives = 292/384 (76%)
 Frame = +1

Query: 1    GEVIIGDGGFVFQLEKRGYVKAGPWTPEAAVEHPEAVIQLHREFLRAGSDVMQAFTFYAS 180
            GEV+IGDGGFVF LEKRGYVKAGPWTPEAAVEHPEAV QLHREFLRAGS+VMQ FTFYAS
Sbjct: 20   GEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYAS 79

Query: 181  DDKLENRGNEAASKYGGSNINRKACQLAKQVASEGQNILTLGGVSQTPSYLTGVGKAETQ 360
            +DKLENRGN  A K  G  +N  AC +A+QVA EG + L  GGVSQTPSYL+   + E +
Sbjct: 80   EDKLENRGNYVAEKISGQKVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSETEVK 138

Query: 361  NIFRKQFTVFKEEQVDFLLCEYFEHVEEAEWAVETAKEFNMPVACSLCIGPEGDMKNVPT 540
             IF +Q  VF ++ VDFL+ EYFEHVEEA WAVE  K    P+A ++CIGPEGD+  V  
Sbjct: 139  KIFHQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKTSGKPIAATMCIGPEGDLHGVSP 198

Query: 541  GECAVRLVKAGADIVGINCHHDPFIVLKAMKIMISAVKAAGLKAHFMIQPLGYMTPDASK 720
            GECAVRLVKAGA IVG+NCH DP   L+ +K+M   ++AA LKA+ M   L Y TPD  K
Sbjct: 199  GECAVRLVKAGAAIVGVNCHFDPSTSLQTIKLMKEGLEAARLKAYLMSHALAYHTPDCGK 258

Query: 721  QGFIDLPEFPFALEPRICTRFDMQKYAREAYEAGIRYIGGCCGFEAYHIRAVAEELAKER 900
            QGFIDLPEFPF LEPR+ TR+D+QKYAREAY  G+RYIGGCCGFE YHIRA+AEELA ER
Sbjct: 259  QGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPER 318

Query: 901  GRFPAGSEKHEPWGEGLKMHTKPWVRARAKREYWEKLCPCTGRPYSASLAVPDQWGVTAG 1080
            G  P  SEKH  WG GL MHTKPW+RARA++EYW+ L   +GRPY+ S++ PD WGVT G
Sbjct: 319  GFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASGRPYNPSMSKPDAWGVTKG 378

Query: 1081 HEELKQQSAKTDDKEIEDLYKQLK 1152
              EL QQ   T ++++  L+++ K
Sbjct: 379  AAELMQQKEATTEQQLRALFEKQK 402

>sp|Q95332|BHMT_PIG Betaine--homocysteine S-methyltransferase
          Length = 278

 Score =  366 bits (939), Expect = e-101
 Identities = 177/260 (68%), Positives = 203/260 (78%)
 Frame = +1

Query: 1   GEVIIGDGGFVFQLEKRGYVKAGPWTPEAAVEHPEAVIQLHREFLRAGSDVMQAFTFYAS 180
           GEV+IGDGGFVF LEKRGYVKAGPWTPEAAVEHPEAV QLHREFLRAGS+VMQ FTFYAS
Sbjct: 20  GEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYAS 79

Query: 181 DDKLENRGNEAASKYGGSNINRKACQLAKQVASEGQNILTLGGVSQTPSYLTGVGKAETQ 360
           +DKLENRGN  A K  G  +N  AC +A+QVA EG + L  GGVSQTPSYL+   + E +
Sbjct: 80  EDKLENRGNYVAEKISGQKVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSETEVK 138

Query: 361 NIFRKQFTVFKEEQVDFLLCEYFEHVEEAEWAVETAKEFNMPVACSLCIGPEGDMKNVPT 540
            +FR+Q  VF ++ VDFL+ EYFEHVEEA WAVE  K    PVA ++CIGPEGD+  V  
Sbjct: 139 KVFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDLHGVTP 198

Query: 541 GECAVRLVKAGADIVGINCHHDPFIVLKAMKIMISAVKAAGLKAHFMIQPLGYMTPDASK 720
           G+CAVRLVKAGA IVG+NCH DP I L+ +K+M   ++AAGLKAH M QPL Y TPD  K
Sbjct: 199 GQCAVRLVKAGASIVGVNCHFDPTISLQTVKLMKEGLQAAGLKAHLMSQPLAYHTPDCGK 258

Query: 721 QGFIDLPEFPFALEPRICTR 780
           QGFIDLPEFPF LEPR+ TR
Sbjct: 259 QGFIDLPEFPFGLEPRVATR 278

>sp|Q9SDL7|HMT1_ARATH Homocysteine S-methyltransferase 1 (S-methylmethionine:homocysteine
           methyltransferase 1) (SMM:Hcy S-methyltransferase 1)
           (AtHMT-1)
          Length = 326

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 79/328 (24%), Positives = 131/328 (39%), Gaps = 30/328 (9%)
 Frame = +1

Query: 1   GEVIIGDGGFVFQLEKRGYVKAGP-WTPEAAVEHPEAVIQLHREFLRAGSDVMQAFTFYA 177
           G   + DGGF  QLE  G     P W+  + +++PE + ++H E+L AG+D++   ++ A
Sbjct: 18  GGCAVVDGGFATQLEIHGAAINDPLWSAVSLIKNPELIKRVHMEYLEAGADIVVTSSYQA 77

Query: 178 SDDKLENRGN------------------------EAASKYGGSNINRKACQLAKQVASEG 285
           +     +RG                         E  SK  G + NR    +A  + S G
Sbjct: 78  TIPGFLSRGLSIEESESLLQKSVELAVEARDRFWEKVSKVSGHSYNR--ALVAASIGSYG 135

Query: 286 QNILTLGGVSQTPSYLTGVGKAETQNIFRKQFTVFKEEQVDFLLCEYFEHVEEAEWAVET 465
             +    G   +  Y   V   + ++  R++  V  E   D L  E   +  EA+  VE 
Sbjct: 136 AYL--ADGSEYSGHYGENVSLDKLKDFHRRRLQVLVEAGPDLLAFETIPNKLEAQACVEL 193

Query: 466 AKEFNMPVACSLCIGPEGDMKNVPTG----ECAVRLVKA-GADIVGINCHHDPFIVLKAM 630
            +E  + +   +C     D +  P+G    EC   L K+     VGINC    FI     
Sbjct: 194 LEEEKVQIPAWICF-TSVDGEKAPSGESFEECLEPLNKSNNIYAVGINCAPPQFI----- 247

Query: 631 KIMISAVKAAGLKAHFMIQPLGYMTPDASKQGFIDLPEFPFALEPRICTRFDMQKYAREA 810
           + +I        KA  +    G +    +KQ    LP   F  +       + + +A + 
Sbjct: 248 ENLIRKFAKLTKKAIVVYPNSGEVWDGKAKQW---LPSQCFGDD-------EFEMFATKW 297

Query: 811 YEAGIRYIGGCCGFEAYHIRAVAEELAK 894
            + G + IGGCC      I A++ +L +
Sbjct: 298 RDLGAKLIGGCCRTTPSTINAISRDLKR 325

>sp|Q55786|METH_SYNY3 Methionine synthase (5-methyltetrahydrofolate--homocysteine
           methyltransferase) (Methionine synthase, vitamin-B12
           dependent isozyme) (MS)
          Length = 1195

 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 69/287 (24%), Positives = 122/287 (42%), Gaps = 21/287 (7%)
 Frame = +1

Query: 100 PEAVIQLHREFLRAGSDVMQAFTFYASDDKLENRGNEAASKYGGSNINRKACQLAKQVAS 279
           PEAV  +HR F  AG+DV++  TF  +   L        S Y    +N+ A +LAK VA+
Sbjct: 54  PEAVATVHRAFYEAGADVVETDTFGGTPLVLAEYDLADQSYY----LNKAAAELAKAVAA 109

Query: 280 EGQN-------ILTLGGVSQTPSYLTGVGKAETQNIFRKQFTVFKEEQVDFLLCEYFEHV 438
           E            ++G  ++ P+ L  V     ++ +  Q     +  VD LL E  + V
Sbjct: 110 EFSTPEKPRFVAGSMGPGTKLPT-LGHVDYDSLKDAYVVQVRGLYDGGVDLLLVETCQDV 168

Query: 439 EEAEWAVETAKEF------NMPVACSLCIGPEGDMKNVPTGECAVRLVKA-GADIVGINC 597
            + + A+   ++        +P+  S+ +   G M        A+ +++    DI+G+NC
Sbjct: 169 LQIKAALNAIEQVFAEKGDRLPLMVSVTMETMGTMLVGTEMAAALAILEPYPIDILGLNC 228

Query: 598 HHDPFIVLKAMKIM-------ISAVKAAGLKAHFMIQPLGYMTPDASKQGFIDLPEFPFA 756
              P ++ + +K +       +S +  AGL  +   Q    +TP   +   +   E    
Sbjct: 229 ATGPDLMKEHVKYLSEHSPFVVSCIPNAGLPENVGGQAFYRLTPMELQMSLMHFIE---- 284

Query: 757 LEPRICTRFDMQKYAREAYEAGIRYIGGCCGFEAYHIRAVAEELAKE 897
                              + G++ IGGCCG    HI+A+A ++AK+
Sbjct: 285 -------------------DLGVQVIGGCCGTRPDHIKALA-DIAKD 311

>sp|Q9FUM8|HMT3_MAIZE Homocysteine S-methyltransferase 3 (S-methylmethionine:homocysteine
           methyltransferase 3) (SMM:Hcy S-methyltransferase 3)
           (ZmHMT-3)
          Length = 338

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 81/345 (23%), Positives = 133/345 (38%), Gaps = 34/345 (9%)
 Frame = +1

Query: 1   GEVIIGDGGFVFQLEKRGYVKAGP-WTPEAAVEHPEAVIQLHREFLRAGSDVMQAFTFYA 177
           G  ++ DGG   +LE  G     P W+ +  +  P  + ++H ++L AG++++   ++ A
Sbjct: 21  GGRLVLDGGLATELEANGADLNDPLWSAKCLLSSPHLIRKVHMDYLEAGANIIITASYQA 80

Query: 178 SDDKLENRGNEAASKYGGSNINRKACQLAKQVASE------------GQNILTLGGVSQT 321
           +    E++G    SK    N+  K+ Q+A +                   IL    +   
Sbjct: 81  TIQGFESKG---FSKEQSENLLTKSVQIALEAREMFLKEHLEKSTPIQHPILVAAALGSY 137

Query: 322 PSYLTG-------VGKAETQNIF----RKQFTVFKEEQVDFLLCEYFEHVEEAEWAVETA 468
            +YL          G+A T+       R++  V  E   D +  E   +  EA+  VE  
Sbjct: 138 GAYLADGSEYSGDYGEAGTKEFLKDFHRRRLQVLAEAGPDLIAFETIPNKLEAQAYVELL 197

Query: 469 KEFNMPVACSLCIGPEGDMKNVPTG----ECAV---RLVKAGADIVGINCHHDPFI---V 618
           +E N+ +   L    + D  +V +G    ECA    +  K GA  VGINC    FI   +
Sbjct: 198 EECNINIPSWLSFNSK-DGVHVVSGDSLIECATIADKCAKVGA--VGINCTPPRFIHGLI 254

Query: 619 LKAMKIMISAVKAAGLKAHFMIQPLGYMTPDASKQGFIDLPEFPFALEPRICTRFDMQKY 798
           L   K+    +         +I P      D  K+ ++         E    +  D   Y
Sbjct: 255 LSIRKVTDKPI---------LIYPNSGERYDGEKKEWV---------ESTGVSDGDFVSY 296

Query: 799 AREAYEAGIRYIGGCCGFEAYHIRAVAEELAKERGRFPAGSEKHE 933
             E  + G   IGGCC      IRA+   L +       G  KH+
Sbjct: 297 VNEWCKDGAALIGGCCRTTPNTIRAIHRTLNQ-------GCHKHQ 334

>sp|Q9FUM9|HMT2_MAIZE Homocysteine S-methyltransferase 2 (S-methylmethionine:homocysteine
           methyltransferase 2) (SMM:Hcy S-methyltransferase 2)
           (ZmHMT-2)
          Length = 339

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 76/332 (22%), Positives = 128/332 (38%), Gaps = 34/332 (10%)
 Frame = +1

Query: 1   GEVIIGDGGFVFQLEKRGYVKAGP-WTPEAAVEHPEAVIQLHREFLRAGSDVMQAFTFYA 177
           G  ++ DGG   +LE  G     P W+ +  +  P  + ++H ++L AG++++   ++ A
Sbjct: 21  GGRLVLDGGLATELEANGADLNDPLWSAKCLLSSPHLIRKVHMDYLEAGANIIITASYQA 80

Query: 178 SDDKLENRGNEAASKYGGSNINRKACQLAKQVASE------------GQNILTLGGVSQT 321
           +    E++G    SK    N+  K+ ++A +                   +L    +   
Sbjct: 81  TIQGFESKG---FSKEQSENLLTKSVEIALEAREMFLKEHLEKSTPIQHPVLVAASLGSY 137

Query: 322 PSYLTG-------VGKAETQNIF----RKQFTVFKEEQVDFLLCEYFEHVEEAEWAVETA 468
            +YL          G+A T+       R++  V  E   D +  E   +  EAE  VE  
Sbjct: 138 GAYLADGSEYSGDYGEAGTKEFLKDFHRRRLQVLAEAGPDLIAFETIPNKLEAEAYVELL 197

Query: 469 KEFNMPVACSLCIGPEGDMKNVPTG----EC---AVRLVKAGADIVGINCHHDPFI---V 618
           +E N+ +        + D  ++ +G    EC   A +  K GA  VGINC    FI   +
Sbjct: 198 EECNINIPAWFSFNSK-DGVHIVSGDSLIECTTIADKCAKVGA--VGINCTPPRFIHGLI 254

Query: 619 LKAMKIMISAVKAAGLKAHFMIQPLGYMTPDASKQGFIDLPEFPFALEPRICTRFDMQKY 798
           L   K+    +         +I P      D  K+ ++         E    +  D   Y
Sbjct: 255 LSIRKVTDKPI---------LIYPNSGERYDGEKKEWV---------ESTGVSDGDFVSY 296

Query: 799 AREAYEAGIRYIGGCCGFEAYHIRAVAEELAK 894
             E  + G   IGGCC      IRA+   L K
Sbjct: 297 VNEWCKDGAVLIGGCCRTTPNTIRAIHRTLNK 328

>sp|Q9M1W4|HMT2_ARATH Homocysteine S-methyltransferase 2 (S-methylmethionine:homocysteine
           methyltransferase 2) (SMM:Hcy S-methyltransferase 2)
           (AtHMT-2)
          Length = 333

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 64/334 (19%), Positives = 130/334 (38%), Gaps = 34/334 (10%)
 Frame = +1

Query: 1   GEVIIGDGGFVFQLEKRGYVKAGP-WTPEAAVEHPEAVIQLHREFLRAGSDVMQAFTFYA 177
           G   + DGG   + E+ G     P W+ +  V  P  +  +H ++L AG+D++ + ++ A
Sbjct: 17  GGYAVIDGGLATEFERHGADLNDPLWSAKCLVTSPHLIHTVHLDYLEAGADIISSASYQA 76

Query: 178 SDDKLENRGNEAASKYGGSNINRKACQLAKQVAS-----------------EGQNILTLG 306
           +    E +G    S+    ++ +K+ ++A +  +                 + + IL   
Sbjct: 77  TIQGFEAKG---FSREESESLLKKSVEIATEARNSYYDKCGTSSSMDDKILKKRPILVAA 133

Query: 307 GVSQTPSYLT-----------GVGKAETQNIFRKQFTVFKEEQVDFLLCEYFEHVEEAEW 453
            V    +YL             +   + ++  R++  V  E   D +  E   +  EA+ 
Sbjct: 134 SVGSYGAYLADGSEYSGIYGDSITLEKLKDFHRRRLQVLAESGADLIAFETIPNKIEAQA 193

Query: 454 AVETAKEFNMPVACSLCIGPEGDMKNVPTGECAVRLVKAGADI-----VGINCHHDPFIV 618
             +  +E ++ +        + D  NV +G+     +    +      VGINC    FI 
Sbjct: 194 FADLLEEGDVKIPGWFSFNSK-DGVNVVSGDSIKECISIAENCEKVVAVGINCTPPRFI- 251

Query: 619 LKAMKIMISAVKAAGLKAHFMIQPLGYMTPDASKQGFIDLPEFPFALEPRICTRFDMQKY 798
            + + + I  V +  +    ++ P    + DA ++ ++         E       D   Y
Sbjct: 252 -EGLVLEIEKVTSKPI----LVYPNSGESYDADRKEWV---------ENTGVGDEDFVSY 297

Query: 799 AREAYEAGIRYIGGCCGFEAYHIRAVAEELAKER 900
             +  +AG+  +GGCC      IRA+ + L   R
Sbjct: 298 VEKWMDAGVSLLGGCCRTTPTTIRAIHKRLVNRR 331

>sp|Q99707|METH_HUMAN Methionine synthase (5-methyltetrahydrofolate--homocysteine
           methyltransferase) (Methionine synthase, vitamin-B12
           dependent) (MS)
          Length = 1265

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 71/303 (23%), Positives = 117/303 (38%), Gaps = 28/303 (9%)
 Frame = +1

Query: 88  AVEHPEAVIQLHREFLRAGSDVMQAFTFYASDDKLENRGNEAAS---KYGGSNINRKAC- 255
           ++  P+ + Q+H+E+L AG+D+++  TF ++     + G E  +       + + RKA  
Sbjct: 71  SITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAE 130

Query: 256 QLAKQVASEGQNILTLGGVSQTPSYLTGVGKAETQNIFRKQFTVFKEEQ--------VDF 411
           ++  Q   +      LG  ++T S    V + + +NI   +     +EQ        VD 
Sbjct: 131 EVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDI 190

Query: 412 LLCEYFEHVEEAEWAVET------AKEFNMPVACS-LCIGPEGDMKNVPTGECAVRLVKA 570
           LL E       A+ A+         K    P+  S   +   G   +  TGE  V  V  
Sbjct: 191 LLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSH 250

Query: 571 GADI-VGINC-----HHDPFIVL--KAMKIMISAVKAAGLKAHFMIQPLGYMTPDASKQG 726
           G  + +G+NC        PFI +  K     +     AGL                    
Sbjct: 251 GEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGL-----------------PNT 293

Query: 727 FIDLPEFPFALEPRICTRFDMQKYARE-AYEAGIRYIGGCCGFEAYHIRAVAEELAKERG 903
           F D  E P            M K+ ++ A +  +  +GGCCG    HIR +AE +   + 
Sbjct: 294 FGDYDETPSM----------MAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKP 343

Query: 904 RFP 912
           R P
Sbjct: 344 RVP 346

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 138,285,284
Number of Sequences: 369166
Number of extensions: 2900368
Number of successful extensions: 8562
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8113
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8547
length of database: 68,354,980
effective HSP length: 113
effective length of database: 47,479,925
effective search space used: 14528857050
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00879

  1. Dr_sW_022_C02
  2. Dr_sW_015_O10