Planaria EST Database

DrC_00868

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00868
         (1249 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q92122|KPYK_XENLA  Pyruvate kinase, muscle isozyme (Cytos...   334   3e-91
sp|O62619|KPYK_DROME  Pyruvate kinase (PK)                        329   9e-90
sp|P11980|KPYM_RAT  Pyruvate kinase, isozymes M1/M2 (Pyruvat...   323   5e-88
sp|P11974|KPYM_RABIT  Pyruvate kinase, isozymes M1/M2 (Pyruv...   323   6e-88
sp|P14618|KPYM_HUMAN  Pyruvate kinase, isozymes M1/M2 (Pyruv...   321   3e-87
sp|P11979|KPYM_FELCA  Pyruvate kinase, isozyme M1 (Pyruvate ...   321   3e-87
sp|P00548|KPYK_CHICK  Pyruvate kinase, muscle isozyme             318   2e-86
sp|Q29536|KPYR_CANFA  Pyruvate kinase, isozyme R                  318   2e-86
sp|P52480|KPYM_MOUSE  Pyruvate kinase, isozyme M2                 317   3e-86
sp|P30613|KPYR_HUMAN  Pyruvate kinase, isozymes R/L (R-type/...   315   2e-85

>sp|Q92122|KPYK_XENLA Pyruvate kinase, muscle isozyme (Cytosolic thyroid hormone binding
            protein) (CTHBP)
          Length = 527

 Score =  334 bits (857), Expect = 3e-91
 Identities = 175/337 (51%), Positives = 229/337 (67%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            +E GG LGS K   LP  A+   A S    Q+L F +E  VDM+F+SFI   ADV  ++E
Sbjct: 193  IENGGMLGSKKGVNLPGAAVDLPAVSSKDIQDLQFGVEQDVDMVFASFIRKAADVHEVRE 252

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
            V+G  G+ IK+++KIE   G+   DEILE +D IM+ RGDLG+E+P EKVF+AQK +I R
Sbjct: 253  VLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGR 312

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C  A KPV+  TQMLESM  KPR TRAE SDVANAVLDGAD ++LS ET++G YP+E ++
Sbjct: 313  CNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVR 372

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              H + REAE+A+FHRQLF +L+    S    DPT+ T               IIV+T S
Sbjct: 373  MQHAIAREAEAAIFHRQLFEELR--RVSPLTRDPTEATAVGAVEASFKCSSGAIIVLTKS 430

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA L++ YRP+ P+I+VTR  Q ARQ HL+RG+ P++Y E   + W+ED+D R+N+A+
Sbjct: 431  GRSAHLLSRYRPRAPIISVTRNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDSRVNFAM 490

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYVP 1037
            D G  RGF K GD VI++TGW  G+G TNT+RV  VP
Sbjct: 491  DIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVVPVP 527

>sp|O62619|KPYK_DROME Pyruvate kinase (PK)
          Length = 533

 Score =  329 bits (844), Expect = 9e-90
 Identities = 170/342 (49%), Positives = 232/342 (67%)
 Frame = +3

Query: 9    ESARCLVEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKAD 188
            +S  C VE GG LGS K   LP   +   A S   + +LLF +E +VDMIF+SFI + A 
Sbjct: 194  DSLTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAA 253

Query: 189  VQRIKEVIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQ 368
            +  I++V+G  G+ IK+++KIE + G+ +LDEI+E  D IM+ RGDLG+E+P EKVF+AQ
Sbjct: 254  LTEIRKVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQ 313

Query: 369  KSIIARCQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMY 548
            K++IARC  A KPV+  TQMLESM  KPR TRAEISDVANAVLDGAD ++LS ET++G Y
Sbjct: 314  KAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEY 373

Query: 549  PVETLQTMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCI 728
            P+E + TM + C+EAE+A++H+ LF DL      +  ID +                  I
Sbjct: 374  PLECVLTMAKTCKEAEAALWHQNLFNDL---VRGAGTIDASHAAAIAAVEAATKAKASAI 430

Query: 729  IVVTTSGRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDL 908
            +V+TTSG+SA  ++ YRP+CP+I VTR AQ ARQ HL+RGL PL+Y E    DW +D+D+
Sbjct: 431  VVITTSGKSAFQVSKYRPRCPIIAVTRFAQTARQAHLYRGLVPLIYKEPGLGDWLKDVDV 490

Query: 909  RINYAIDWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYV 1034
            R+ + +  G   GF+K GD V++VTGW  G+G TNT+R+  V
Sbjct: 491  RVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTV 532

>sp|P11980|KPYM_RAT Pyruvate kinase, isozymes M1/M2 (Pyruvate kinase muscle isozyme)
          Length = 531

 Score =  323 bits (829), Expect = 5e-88
 Identities = 172/337 (51%), Positives = 224/337 (66%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            VE GG LGS K   LP  A+   A S    Q+L F +E  VDM+F+SFI   ADV  +++
Sbjct: 197  VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRK 256

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
            V+G  G+ IK+++KIE   G+   DEILE +D IM+ RGDLG+E+P EKVF+AQK +I R
Sbjct: 257  VLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGR 316

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C  A KPV+  TQMLESM  KPR TRAE SDVANAVLDGAD ++LS ET++G YP+E ++
Sbjct: 317  CNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVR 376

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              H + REAE+A+FHR LF +L    ASS   DP +                 +IV+T S
Sbjct: 377  MQHLIAREAEAAVFHRLLFEELA--RASSQSTDPLEAMAMGSVEASYKCLAAALIVLTES 434

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA  +A YRP+ P+I VTR  Q ARQ HL+RG+ P++  +   D W+ED+DLR+N A+
Sbjct: 435  GRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAM 494

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYVP 1037
            + G  RGF K GD VI++TGW  G+G TNT+RV  VP
Sbjct: 495  NVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531

>sp|P11974|KPYM_RABIT Pyruvate kinase, isozymes M1/M2 (Pyruvate kinase muscle isozyme)
          Length = 531

 Score =  323 bits (828), Expect = 6e-88
 Identities = 172/337 (51%), Positives = 225/337 (66%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            VE GG LGS K   LP  A+   A S    Q+L F +E  VDM+F+SFI   ADV  +++
Sbjct: 197  VENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRK 256

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
            ++G  G+ IK+++KIE   G+   DEILE +D IM+ RGDLG+E+P EKVF+AQK II R
Sbjct: 257  ILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGR 316

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C  A KPV+  TQMLESM  KPR TRAE SDVANAVLDGAD ++LS ET++G YP+E ++
Sbjct: 317  CNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVR 376

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              H + REAE+AMFHR+LF +L    +SSH  D  +                 +IV+T S
Sbjct: 377  MQHLIAREAEAAMFHRKLFEELA--RSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTES 434

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA  +A YRP+ P+I VTR  Q ARQ HL+RG+ P+V  +   + W+ED+DLR+N A+
Sbjct: 435  GRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAM 494

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYVP 1037
            + G  RGF K GD VI++TGW  G+G TNT+RV  VP
Sbjct: 495  NVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531

>sp|P14618|KPYM_HUMAN Pyruvate kinase, isozymes M1/M2 (Pyruvate kinase muscle isozyme)
            (Cytosolic thyroid hormone-binding protein) (CTHBP)
            (THBP1)
          Length = 531

 Score =  321 bits (822), Expect = 3e-87
 Identities = 169/337 (50%), Positives = 226/337 (67%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            VE GG LGS K   LP  A+   A S    Q+L F +E  VDM+F+SFI   +DV  +++
Sbjct: 197  VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRK 256

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
            V+G  G+ IK+++KIE   G+   DEILE +D IM+ RGDLG+E+P EKVF+AQK +I R
Sbjct: 257  VLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGR 316

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C  A KPV+  TQMLESM  KPR TRAE SDVANAVLDGAD ++LS ET++G YP+E ++
Sbjct: 317  CNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVR 376

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              H + REAE+A++H QLF +L+    +    DPT+ T               IIV+T S
Sbjct: 377  MQHLIAREAEAAIYHLQLFEELR--RLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKS 434

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA  +A YRP+ P+I VTR  Q ARQ HL+RG+ P++  +   + W+ED+DLR+N+A+
Sbjct: 435  GRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAM 494

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYVP 1037
            + G  RGF K GD VI++TGW  G+G TNT+RV  VP
Sbjct: 495  NVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531

>sp|P11979|KPYM_FELCA Pyruvate kinase, isozyme M1 (Pyruvate kinase muscle isozyme)
          Length = 531

 Score =  321 bits (822), Expect = 3e-87
 Identities = 171/337 (50%), Positives = 224/337 (66%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            VE GG LGS K   LP  A+   A S    Q+L F +E  VDM+F+SFI   +DV  +++
Sbjct: 197  VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRK 256

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
            V+G  G+ IK+++KIE   G+   DEILE +D IM+ RGDLG+E+P EKVF+AQK +I R
Sbjct: 257  VLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGR 316

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C  A KPV+  TQMLESM  KPR TRAE SDVANAVLDGAD ++LS ET++G YP+E ++
Sbjct: 317  CNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVR 376

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              H + REAE+AMFHR+LF +L     SSH  D  +                 +IV+T S
Sbjct: 377  MQHLIAREAEAAMFHRKLFEELV--RGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTES 434

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA  +A YRP+ P+I VTR  Q ARQ HL+RG+ P+V  +   + W+ED+DLR+N A+
Sbjct: 435  GRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAM 494

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYVP 1037
            + G  RGF K GD VI++TGW  G+G TNT+RV  VP
Sbjct: 495  NVGKARGFFKHGDVVIVLTGWRPGSGFTNTMRVVPVP 531

>sp|P00548|KPYK_CHICK Pyruvate kinase, muscle isozyme
          Length = 530

 Score =  318 bits (816), Expect = 2e-86
 Identities = 168/337 (49%), Positives = 223/337 (66%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            VE GG LGS K   LP  A+   A S    Q+L F +E  VDM+F+SFI   ADV  +++
Sbjct: 196  VENGGMLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQNVDMVFASFIRKAADVHAVRK 255

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
            V+G  G+ IK+++KIE   G+   DEI+E +D IM+ RGDLG+E+P EKVF+AQK +I R
Sbjct: 256  VLGEKGKHIKIISKIENHEGVRRFDEIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGR 315

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C  A KP++  TQMLESM  KPR TRAE SDVANAVLDGAD ++LS ET++G YP+E ++
Sbjct: 316  CNRAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVR 375

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              H + REAE+AMFHRQ F ++  H  S H  +P                   +IV+T S
Sbjct: 376  MQHAIAREAEAAMFHRQQFEEILRH--SVHHREPADAMAAGAVEASFKCLAAALIVMTES 433

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA L++ YRP+ P+I VTR  Q ARQ HL+RG+ P++  +   D W+ED+DLR+N  +
Sbjct: 434  GRSAHLVSRYRPRAPIIAVTRNDQTARQAHLYRGVFPVLCKQPAHDAWAEDVDLRVNLGM 493

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYVP 1037
            + G  RGF K GD VI++TGW  G+G TNT+RV  VP
Sbjct: 494  NVGKARGFFKTGDLVIVLTGWRPGSGYTNTMRVVPVP 530

>sp|Q29536|KPYR_CANFA Pyruvate kinase, isozyme R
          Length = 519

 Score =  318 bits (816), Expect = 2e-86
 Identities = 168/336 (50%), Positives = 225/336 (66%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            VE GG LGS K   LP   +     S    Q+L F +E+ VD++F+SF+   +DV  I+ 
Sbjct: 185  VENGGLLGSRKGVNLPGAEVDLPGLSEQDAQDLRFGVEHNVDIVFASFVRKASDVAAIRA 244

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
             +GP GR IK+++KIE   G+   DEILE +D IM+ RGDLG+E+P EKVF+AQK +I R
Sbjct: 245  ALGPEGRTIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGR 304

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C +A KPV+  TQMLESM  KPR TRAE SDVANAVLDGAD ++LS ET++G +PVE ++
Sbjct: 305  CNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGKFPVEAVK 364

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              HR+ REAE+A++HRQLF +L+   A+    DPT+ T               IIV+T +
Sbjct: 365  MQHRIAREAEAAVYHRQLFEELR--RAAPLSRDPTEVTAIATVEAAFKCCAAAIIVLTKT 422

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA L++ YRP+  VI VTR AQ ARQ HL RG+ PL+Y+E     W++D+D R+ + I
Sbjct: 423  GRSAQLLSRYRPRAAVIAVTRSAQAARQAHLCRGVFPLLYSEPPEAIWADDVDRRVQFGI 482

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYV 1034
            + G  RGFL+ GD VI+VTGW  G+G TN +RV  +
Sbjct: 483  ESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 518

>sp|P52480|KPYM_MOUSE Pyruvate kinase, isozyme M2
          Length = 531

 Score =  317 bits (813), Expect = 3e-86
 Identities = 169/337 (50%), Positives = 223/337 (66%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            VE GG LGS K   LP  A+   A S    Q+L F +E  VDM+F+SFI   ADV  +++
Sbjct: 197  VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRK 256

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
            V+G  G+ IK+++KIE   G+   DEILE +D IM+ RGDLG+E+P EKVF+AQK +I R
Sbjct: 257  VLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGR 316

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C  A KPV+  TQMLE M  KPR TRAE SDVANAVLDGAD ++LS ET++G YP+E ++
Sbjct: 317  CNRAGKPVICSTQMLEIMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVR 376

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              H + REAE+A++H QLF +L+    +    DPT+                 IIV+T S
Sbjct: 377  MQHLIAREAEAAIYHLQLFEELR--RLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKS 434

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA  +A YRP+ P+I VTR  Q ARQ HL+RG+ P++  +   + W+ED+DLR+N A+
Sbjct: 435  GRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLNAWAEDVDLRVNLAM 494

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYVP 1037
            D G  RGF K GD VI++TGW  G+G TNT+RV  VP
Sbjct: 495  DVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531

>sp|P30613|KPYR_HUMAN Pyruvate kinase, isozymes R/L (R-type/L-type pyruvate kinase) (Red
            cell/liver pyruvate kinase)
          Length = 574

 Score =  315 bits (806), Expect = 2e-85
 Identities = 166/336 (49%), Positives = 224/336 (66%)
 Frame = +3

Query: 27   VEQGGRLGSSKRCILPRNALLKHAFSVSFRQNLLFALENQVDMIFSSFIDSKADVQRIKE 206
            VE GG LGS K   LP   +     S    ++L F +E+ VD++F+SF+   +DV  ++ 
Sbjct: 240  VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRA 299

Query: 207  VIGPVGRGIKLVAKIETKNGIVHLDEILEEADAIMIGRGDLGLELPIEKVFVAQKSIIAR 386
             +GP G GIK+++KIE   G+   DEILE +D IM+ RGDLG+E+P EKVF+AQK +I R
Sbjct: 300  ALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGR 359

Query: 387  CQMAKKPVMVVTQMLESMRYKPRATRAEISDVANAVLDGADGLVLSVETSRGMYPVETLQ 566
            C +A KPV+  TQMLESM  KPR TRAE SDVANAVLDGAD ++LS ET++G +PVE ++
Sbjct: 360  CNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVK 419

Query: 567  TMHRVCREAESAMFHRQLFLDLKIHEASSHMIDPTKTTXXXXXXXXXXXXXXCIIVVTTS 746
              H + REAE+A++HRQLF +L+   A+    DPT+ T               IIV+TT+
Sbjct: 420  MQHAIAREAEAAVYHRQLFEELR--RAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTT 477

Query: 747  GRSATLIASYRPQCPVITVTRQAQVARQCHLWRGLHPLVYTEYKADDWSEDMDLRINYAI 926
            GRSA L++ YRP+  VI VTR AQ ARQ HL RG+ PL+Y E     W++D+D R+ + I
Sbjct: 478  GRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGI 537

Query: 927  DWGCNRGFLKPGDPVIIVTGWIAGTGSTNTVRVFYV 1034
            + G  RGFL+ GD VI+VTGW  G+G TN +RV  +
Sbjct: 538  ESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 573

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 142,801,753
Number of Sequences: 369166
Number of extensions: 2855216
Number of successful extensions: 7776
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7305
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7687
length of database: 68,354,980
effective HSP length: 113
effective length of database: 47,479,925
effective search space used: 14338937350
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00868

  1. Dr_sW_021_P21
  2. Dr_sW_011_N18