Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00860 (746 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9DBP5|KCY_MOUSE UMP-CMP kinase (Cytidylate kinase) (Deo... 200 3e-51 sp|P30085|KCY_HUMAN UMP-CMP kinase (Cytidylate kinase) (Deo... 200 3e-51 sp|Q29561|KCY_PIG UMP-CMP kinase (Cytidylate kinase) (Deoxy... 199 9e-51 sp|O04905|UMPK_ARATH Uridylate kinase (UK) (Uridine monopho... 167 3e-41 sp|P15700|UMPK_YEAST Uridylate kinase (UK) (Uridine monopho... 163 4e-40 sp|P20425|KCY_DICDI Cytidylate kinase (Deoxycytidylate kina... 162 7e-40 sp|O24464|KAD_PRUAR Adenylate kinase (ATP-AMP transphosphor... 162 9e-40 sp|O59771|UMPK_SCHPO Probable uridylate kinase (UK) (Uridin... 152 1e-36 sp|P39069|KAD1_RAT Adenylate kinase isoenzyme 1 (ATP-AMP tr... 135 1e-31 sp|P12115|KAD_CYPCA Adenylate kinase (ATP-AMP transphosphor... 134 3e-31
>sp|Q9DBP5|KCY_MOUSE UMP-CMP kinase (Cytidylate kinase) (Deoxycytidylate kinase) (Cytidine monophosphate kinase) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) (Uridine monophosphate kinase) Length = 196 Score = 200 bits (509), Expect = 3e-51 Identities = 94/181 (51%), Positives = 133/181 (73%), Gaps = 7/181 (3%) Frame = +2 Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265 V FVLGGPG+GKGTQC I + +GY H+SAG+LLR+E+ N +SQYG+LI+K+++EG IVP Sbjct: 5 VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVP 64 Query: 266 VEITCSLIEKAMKA-----SGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSE 430 VEIT SL+++ M + K+KFLIDGFPRNQ+NL GWNK M K + VL+ +C+ Sbjct: 65 VEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNN 124 Query: 431 DACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEV 604 + C++RCL RG +GR DDN E+L+KR+ + KPIID +++ KV K++ +++EV Sbjct: 125 EICIERCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSVDEV 184 Query: 605 F 607 F Sbjct: 185 F 185
>sp|P30085|KCY_HUMAN UMP-CMP kinase (Cytidylate kinase) (Deoxycytidylate kinase) (Cytidine monophosphate kinase) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) (Uridine monophosphate kinase) Length = 196 Score = 200 bits (509), Expect = 3e-51 Identities = 94/181 (51%), Positives = 133/181 (73%), Gaps = 7/181 (3%) Frame = +2 Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265 V FVLGGPG+GKGTQC I + +GY H+SAG+LLR+E+ N +SQYG+LI+K+++EG IVP Sbjct: 5 VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVP 64 Query: 266 VEITCSLIEKAMKA-----SGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSE 430 VEIT SL+++ M + K+KFLIDGFPRNQ+NL GWNK M K + VL+ +C+ Sbjct: 65 VEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNN 124 Query: 431 DACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEV 604 + C++RCL RG +GR DDN E+L+KR+ + KPIID +++ KV K++ +++EV Sbjct: 125 EICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEV 184 Query: 605 F 607 F Sbjct: 185 F 185
>sp|Q29561|KCY_PIG UMP-CMP kinase (Cytidylate kinase) (Deoxycytidylate kinase) (Cytidine monophosphate kinase) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) (Uridine monophosphate kinase) Length = 196 Score = 199 bits (505), Expect = 9e-51 Identities = 93/181 (51%), Positives = 132/181 (72%), Gaps = 7/181 (3%) Frame = +2 Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265 V FVLGGPG+GKGTQC I + +GY H+SAG+LLR+E+ N +SQYG+LI+K++++G IVP Sbjct: 5 VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKDGKIVP 64 Query: 266 VEITCSLIEKAMKA-----SGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSE 430 VEIT SL+ + M + K+KFLIDGFPRNQ+NL GWNK M K + VL+ +C+ Sbjct: 65 VEITISLLRREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNN 124 Query: 431 DACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEV 604 + C++RCL RG +GR DDN E+L+KR+ + KPIID +++ KV K++ +++EV Sbjct: 125 EICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEV 184 Query: 605 F 607 F Sbjct: 185 F 185
>sp|O04905|UMPK_ARATH Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase) (UMP/CMP kinase) Length = 202 Score = 167 bits (423), Expect = 3e-41 Identities = 90/195 (46%), Positives = 126/195 (64%) Frame = +2 Query: 47 SSGSGDVETQKFSVTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGD 226 ++GSG +K +V FVLGGPGSGKGTQC I + +GY H+SAGDLLR E + S+ G Sbjct: 7 ANGSG----KKPTVIFVLGGPGSGKGTQCAYIVEHYGYTHLSAGDLLRAEI-KSGSENGT 61 Query: 227 LIKKHMQEGSIVPVEITCSLIEKAMKASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIET 406 +I+ ++EG IVP E+T L++KA++ +G KFLIDGFPRN+ N + KV ++ + Sbjct: 62 MIQNMIKEGKIVPSEVTIKLLQKAIQENGNDKFLIDGFPRNEENRAAFEKVT--EIEPKF 119 Query: 407 VLYIECSEDACVKRCLGRGTGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGD 586 VL+ +C E+ KR LGR GR DDN ET++KR F P+I +++ + KV K+N Sbjct: 120 VLFFDCPEEEMEKRLLGRNQGREDDNIETIRKRFKVFLESSLPVIHYYEAKGKVRKINAA 179 Query: 587 LTIEEVFAIIKDKFS 631 IE VF +K FS Sbjct: 180 KPIEAVFEEVKAIFS 194
>sp|P15700|UMPK_YEAST Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase) Length = 204 Score = 163 bits (413), Expect = 4e-40 Identities = 84/185 (45%), Positives = 124/185 (67%), Gaps = 5/185 (2%) Frame = +2 Query: 83 SVTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGDLIKKHMQEGSIV 262 SV FVLGGPG+GKGTQC + K + ++H+SAGDLLR E+ A SQYG+LIK ++EG IV Sbjct: 17 SVIFVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQYGELIKNCIKEGQIV 76 Query: 263 PVEITCSLIEKAMK---ASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSED 433 P EIT +L+ A+ + K KFLIDGFPR + + + D V + +L+ +C ED Sbjct: 77 PQEITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFER---DIVESKFILFFDCPED 133 Query: 434 ACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEVF 607 ++R L RG +GR DDN E++KKR FK P+I++F+ ++KV++V D ++E+V+ Sbjct: 134 IMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVY 193 Query: 608 AIIKD 622 ++D Sbjct: 194 KDVQD 198
>sp|P20425|KCY_DICDI Cytidylate kinase (Deoxycytidylate kinase) (UMP-CMP kinase) Length = 194 Score = 162 bits (411), Expect = 7e-40 Identities = 82/192 (42%), Positives = 126/192 (65%), Gaps = 2/192 (1%) Frame = +2 Query: 65 VETQKFSVTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGDLIKKHM 244 +E K +V FVLGGPGSGKGTQC NI + FG++H+SAGDLLR+E+ + S+ G++I + Sbjct: 1 MEKSKPNVVFVLGGPGSGKGTQCANIVRDFGWVHLSAGDLLRQEQQSG-SKDGEMIATMI 59 Query: 245 QEGSIVPVEITCSLIEKAMKASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIEC 424 + G IVP +T L++ A+ A+ FL+DGFPRN+ N + W + M D V + VL+ +C Sbjct: 60 KNGEIVPSIVTVKLLKNAIDANQGKNFLVDGFPRNEENNNSWEENMKDFVDTKFVLFFDC 119 Query: 425 SEDACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIE 598 E+ +R L RG +GR DDN E++KKR F + K +IDH++K +KV + + + Sbjct: 120 PEEVMTQRLLKRGESSGRSDDNIESIKKRFNTFNVQTKLVIDHYNKFDKVKIIPANRDVN 179 Query: 599 EVFAIIKDKFST 634 EV+ +++ F + Sbjct: 180 EVYNDVENLFKS 191
>sp|O24464|KAD_PRUAR Adenylate kinase (ATP-AMP transphosphorylase) Length = 231 Score = 162 bits (410), Expect = 9e-40 Identities = 83/182 (45%), Positives = 118/182 (64%) Frame = +2 Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265 VTFVLGGPGSGKGTQC I + FG+ H+SAGDLLR E + S YG +I ++EG IVP Sbjct: 49 VTFVLGGPGSGKGTQCAKIVEAFGFTHVSAGDLLRRE-IASGSAYGSVILSTIREGKIVP 107 Query: 266 VEITCSLIEKAMKASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSEDACVK 445 ++T LI+K M++S KFLIDGFPR++ N + + + + VL+ +C E VK Sbjct: 108 SQVTVELIQKEMESSDNYKFLIDGFPRSEENRKAFEQTIG--AEPDVVLFFDCPEQEMVK 165 Query: 446 RCLGRGTGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEVFAIIKDK 625 R L R GRVDDN +T+KKRL F P+I+++ + K+ K+N T++E+F ++ Sbjct: 166 RVLNRNQGRVDDNIDTIKKRLEIFDELNWPVINYYSQRGKLHKINAVGTVDEIFEKVRPI 225 Query: 626 FS 631 F+ Sbjct: 226 FA 227
>sp|O59771|UMPK_SCHPO Probable uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase) Length = 191 Score = 152 bits (383), Expect = 1e-36 Identities = 77/182 (42%), Positives = 120/182 (65%), Gaps = 6/182 (3%) Frame = +2 Query: 80 FSVTFVLGGPGSGKGTQCINIAKTFG-YLHISAGDLLREEKDNANSQYGDLIKKHMQEGS 256 ++V FVLGGPG+GKGTQC +A+ F ++HISAGD LREE++ S+YG+LIK+++++G Sbjct: 2 YNVIFVLGGPGAGKGTQCDRLAEKFDKFVHISAGDCLREEQNRPGSKYGNLIKEYIKDGK 61 Query: 257 IVPVEITCSLIEKAMKA---SGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECS 427 IVP+EIT SL+E MK G KFLIDGFPR + +G+ K + + LY C Sbjct: 62 IVPMEITISLLETKMKECHDKGIDKFLIDGFpreMDQCEGFEKSVCP---AKFALYFRCG 118 Query: 428 EDACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEE 601 ++ +KR + RG +GR DDN E++KKR V + P++++ +N+++ ++ + + Sbjct: 119 QETMLKRLIHRGKTSGRSDDNIESIKKRFVTYTKASMPVVEYLKSQNRLITIDAEQDPDA 178 Query: 602 VF 607 VF Sbjct: 179 VF 180
>sp|P39069|KAD1_RAT Adenylate kinase isoenzyme 1 (ATP-AMP transphosphorylase) (AK1) (Myokinase) Length = 194 Score = 135 bits (340), Expect = 1e-31 Identities = 71/183 (38%), Positives = 111/183 (60%), Gaps = 4/183 (2%) Frame = +2 Query: 74 QKFSVTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGDLIKKHMQEG 253 +K + FV+GGPGSGKGTQC I + +GY H+S GDLLR E + +S+ G ++ M++G Sbjct: 6 KKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSSR-GKMLSSIMEKG 64 Query: 254 SIVPVEITCSLIEKAM--KASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECS 427 +VP+E ++ AM K + FLIDG+PR + + + ++ +LY++ Sbjct: 65 ELVPLETVLDMLRDAMFAKVDSSNGFLIDGYpreVKQGEEFERKIAQPT---LLLYVDAG 121 Query: 428 EDACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEE 601 + +R L RG +GRVDDNEET+KKRL + +P+I +DK V KVN + +++ Sbjct: 122 PETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVISFYDKRGIVRKVNAEGSVDT 181 Query: 602 VFA 610 VF+ Sbjct: 182 VFS 184
>sp|P12115|KAD_CYPCA Adenylate kinase (ATP-AMP transphosphorylase) Length = 193 Score = 134 bits (337), Expect = 3e-31 Identities = 73/181 (40%), Positives = 112/181 (61%), Gaps = 4/181 (2%) Frame = +2 Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHISAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265 + FV+GGPGSGKGTQC I + +GY H+S+GDLLR E + S+ G ++ MQ+G +VP Sbjct: 9 IVFVVGGPGSGKGTQCEKIVEKYGYTHLSSGDLLRAEV-ASGSERGKQLQAIMQKGELVP 67 Query: 266 VEITCSLIEKAM--KASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSEDAC 439 ++ +I+ AM KA +LIDG+PR + + K + +LYI+ + Sbjct: 68 LDTVLDMIKDAMIAKADVSKGYLIDGYpreVKQGEEFEKKIGAPA---LLLYIDAKAETM 124 Query: 440 VKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEVFAI 613 V+R + RG +GR DDNEET+KKRL + +P+I +++ V K+N +L ++EVFAI Sbjct: 125 VQRLMKRGQTSGRSDDNEETIKKRLDLYYKATEPVIAYYETRGIVRKINSELPVDEVFAI 184 Query: 614 I 616 + Sbjct: 185 V 185
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,710,609 Number of Sequences: 369166 Number of extensions: 1692327 Number of successful extensions: 5377 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4796 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5013 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6776504000 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)