Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_N14
(746 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9DBP5|KCY_MOUSE UMP-CMP kinase (Cytidylate kinase) (Deo... 200 4e-51
sp|P30085|KCY_HUMAN UMP-CMP kinase (Cytidylate kinase) (Deo... 200 4e-51
sp|Q29561|KCY_PIG UMP-CMP kinase (Cytidylate kinase) (Deoxy... 198 1e-50
sp|O04905|UMPK_ARATH Uridylate kinase (UK) (Uridine monopho... 167 4e-41
sp|P15700|UMPK_YEAST Uridylate kinase (UK) (Uridine monopho... 163 5e-40
sp|O24464|KAD_PRUAR Adenylate kinase (ATP-AMP transphosphor... 162 7e-40
sp|P20425|KCY_DICDI Cytidylate kinase (Deoxycytidylate kina... 162 9e-40
sp|O59771|UMPK_SCHPO Probable uridylate kinase (UK) (Uridin... 151 2e-36
sp|P39069|KAD1_RAT Adenylate kinase isoenzyme 1 (ATP-AMP tr... 135 2e-31
sp|P12115|KAD_CYPCA Adenylate kinase (ATP-AMP transphosphor... 134 3e-31
>sp|Q9DBP5|KCY_MOUSE UMP-CMP kinase (Cytidylate kinase) (Deoxycytidylate kinase)
(Cytidine monophosphate kinase) (Uridine
monophosphate/cytidine monophosphate kinase) (UMP/CMP
kinase) (UMP/CMPK) (Uridine monophosphate kinase)
Length = 196
Score = 200 bits (508), Expect = 4e-51
Identities = 94/181 (51%), Positives = 133/181 (73%), Gaps = 7/181 (3%)
Frame = +2
Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265
V FVLGGPG+GKGTQC I + +GY H+SAG+LLR+E+ N +SQYG+LI+K+++EG IVP
Sbjct: 5 VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVP 64
Query: 266 VEITCSLIEKAMKA-----SGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSE 430
VEIT SL+++ M + K+KFLIDGFPRNQ+NL GWNK M K + VL+ +C+
Sbjct: 65 VEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNN 124
Query: 431 DACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEV 604
+ C++RCL RG +GR DDN E+L+KR+ + KPIID +++ KV K++ +++EV
Sbjct: 125 EICIERCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSVDEV 184
Query: 605 F 607
F
Sbjct: 185 F 185
>sp|P30085|KCY_HUMAN UMP-CMP kinase (Cytidylate kinase) (Deoxycytidylate kinase)
(Cytidine monophosphate kinase) (Uridine
monophosphate/cytidine monophosphate kinase) (UMP/CMP
kinase) (UMP/CMPK) (Uridine monophosphate kinase)
Length = 196
Score = 200 bits (508), Expect = 4e-51
Identities = 94/181 (51%), Positives = 133/181 (73%), Gaps = 7/181 (3%)
Frame = +2
Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265
V FVLGGPG+GKGTQC I + +GY H+SAG+LLR+E+ N +SQYG+LI+K+++EG IVP
Sbjct: 5 VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVP 64
Query: 266 VEITCSLIEKAMKA-----SGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSE 430
VEIT SL+++ M + K+KFLIDGFPRNQ+NL GWNK M K + VL+ +C+
Sbjct: 65 VEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNN 124
Query: 431 DACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEV 604
+ C++RCL RG +GR DDN E+L+KR+ + KPIID +++ KV K++ +++EV
Sbjct: 125 EICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEV 184
Query: 605 F 607
F
Sbjct: 185 F 185
>sp|Q29561|KCY_PIG UMP-CMP kinase (Cytidylate kinase) (Deoxycytidylate kinase)
(Cytidine monophosphate kinase) (Uridine
monophosphate/cytidine monophosphate kinase) (UMP/CMP
kinase) (UMP/CMPK) (Uridine monophosphate kinase)
Length = 196
Score = 198 bits (504), Expect = 1e-50
Identities = 93/181 (51%), Positives = 132/181 (72%), Gaps = 7/181 (3%)
Frame = +2
Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265
V FVLGGPG+GKGTQC I + +GY H+SAG+LLR+E+ N +SQYG+LI+K++++G IVP
Sbjct: 5 VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKDGKIVP 64
Query: 266 VEITCSLIEKAMKA-----SGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSE 430
VEIT SL+ + M + K+KFLIDGFPRNQ+NL GWNK M K + VL+ +C+
Sbjct: 65 VEITISLLRREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNN 124
Query: 431 DACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEV 604
+ C++RCL RG +GR DDN E+L+KR+ + KPIID +++ KV K++ +++EV
Sbjct: 125 EICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEV 184
Query: 605 F 607
F
Sbjct: 185 F 185
>sp|O04905|UMPK_ARATH Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase)
(UMP/CMP kinase)
Length = 202
Score = 167 bits (422), Expect = 4e-41
Identities = 90/195 (46%), Positives = 126/195 (64%)
Frame = +2
Query: 47 SSGSGDVETQKFSVTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGD 226
++GSG +K +V FVLGGPGSGKGTQC I + +GY H+SAGDLLR E + S+ G
Sbjct: 7 ANGSG----KKPTVIFVLGGPGSGKGTQCAYIVEHYGYTHLSAGDLLRAEI-KSGSENGT 61
Query: 227 LIKKHMQEGSIVPVEITCSLIEKAMKASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIET 406
+I+ ++EG IVP E+T L++KA++ +G KFLIDGFPRN+ N + KV ++ +
Sbjct: 62 MIQNMIKEGKIVPSEVTIKLLQKAIQENGNDKFLIDGFPRNEENRAAFEKVT--EIEPKF 119
Query: 407 VLYIECSEDACVKRCLGRGTGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGD 586
VL+ +C E+ KR LGR GR DDN ET++KR F P+I +++ + KV K+N
Sbjct: 120 VLFFDCPEEEMEKRLLGRNQGREDDNIETIRKRFKVFLESSLPVIHYYEAKGKVRKINAA 179
Query: 587 LTIEEVFAIIKDKFS 631
IE VF +K FS
Sbjct: 180 KPIEAVFEEVKAIFS 194
>sp|P15700|UMPK_YEAST Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase)
Length = 204
Score = 163 bits (412), Expect = 5e-40
Identities = 84/185 (45%), Positives = 124/185 (67%), Gaps = 5/185 (2%)
Frame = +2
Query: 83 SVTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGDLIKKHMQEGSIV 262
SV FVLGGPG+GKGTQC + K + ++H+SAGDLLR E+ A SQYG+LIK ++EG IV
Sbjct: 17 SVIFVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQYGELIKNCIKEGQIV 76
Query: 263 PVEITCSLIEKAMK---ASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSED 433
P EIT +L+ A+ + K KFLIDGFPR + + + D V + +L+ +C ED
Sbjct: 77 PQEITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFER---DIVESKFILFFDCPED 133
Query: 434 ACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEVF 607
++R L RG +GR DDN E++KKR FK P+I++F+ ++KV++V D ++E+V+
Sbjct: 134 IMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVY 193
Query: 608 AIIKD 622
++D
Sbjct: 194 KDVQD 198
>sp|O24464|KAD_PRUAR Adenylate kinase (ATP-AMP transphosphorylase)
Length = 231
Score = 162 bits (411), Expect = 7e-40
Identities = 84/182 (46%), Positives = 118/182 (64%)
Frame = +2
Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265
VTFVLGGPGSGKGTQC I + FG+ HVSAGDLLR E + S YG +I ++EG IVP
Sbjct: 49 VTFVLGGPGSGKGTQCAKIVEAFGFTHVSAGDLLRRE-IASGSAYGSVILSTIREGKIVP 107
Query: 266 VEITCSLIEKAMKASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSEDACVK 445
++T LI+K M++S KFLIDGFPR++ N + + + + VL+ +C E VK
Sbjct: 108 SQVTVELIQKEMESSDNYKFLIDGFPRSEENRKAFEQTIG--AEPDVVLFFDCPEQEMVK 165
Query: 446 RCLGRGTGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEVFAIIKDK 625
R L R GRVDDN +T+KKRL F P+I+++ + K+ K+N T++E+F ++
Sbjct: 166 RVLNRNQGRVDDNIDTIKKRLEIFDELNWPVINYYSQRGKLHKINAVGTVDEIFEKVRPI 225
Query: 626 FS 631
F+
Sbjct: 226 FA 227
>sp|P20425|KCY_DICDI Cytidylate kinase (Deoxycytidylate kinase) (UMP-CMP kinase)
Length = 194
Score = 162 bits (410), Expect = 9e-40
Identities = 82/192 (42%), Positives = 126/192 (65%), Gaps = 2/192 (1%)
Frame = +2
Query: 65 VETQKFSVTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGDLIKKHM 244
+E K +V FVLGGPGSGKGTQC NI + FG++H+SAGDLLR+E+ + S+ G++I +
Sbjct: 1 MEKSKPNVVFVLGGPGSGKGTQCANIVRDFGWVHLSAGDLLRQEQQSG-SKDGEMIATMI 59
Query: 245 QEGSIVPVEITCSLIEKAMKASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIEC 424
+ G IVP +T L++ A+ A+ FL+DGFPRN+ N + W + M D V + VL+ +C
Sbjct: 60 KNGEIVPSIVTVKLLKNAIDANQGKNFLVDGFPRNEENNNSWEENMKDFVDTKFVLFFDC 119
Query: 425 SEDACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIE 598
E+ +R L RG +GR DDN E++KKR F + K +IDH++K +KV + + +
Sbjct: 120 PEEVMTQRLLKRGESSGRSDDNIESIKKRFNTFNVQTKLVIDHYNKFDKVKIIPANRDVN 179
Query: 599 EVFAIIKDKFST 634
EV+ +++ F +
Sbjct: 180 EVYNDVENLFKS 191
>sp|O59771|UMPK_SCHPO Probable uridylate kinase (UK) (Uridine monophosphate kinase) (UMP
kinase)
Length = 191
Score = 151 bits (382), Expect = 2e-36
Identities = 76/182 (41%), Positives = 120/182 (65%), Gaps = 6/182 (3%)
Frame = +2
Query: 80 FSVTFVLGGPGSGKGTQCINIAKTFG-YLHVSAGDLLREEKDNANSQYGDLIKKHMQEGS 256
++V FVLGGPG+GKGTQC +A+ F ++H+SAGD LREE++ S+YG+LIK+++++G
Sbjct: 2 YNVIFVLGGPGAGKGTQCDRLAEKFDKFVHISAGDCLREEQNRPGSKYGNLIKEYIKDGK 61
Query: 257 IVPVEITCSLIEKAMKA---SGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECS 427
IVP+EIT SL+E MK G KFLIDGFPR + +G+ K + + LY C
Sbjct: 62 IVPMEITISLLETKMKECHDKGIDKFLIDGFpreMDQCEGFEKSVCP---AKFALYFRCG 118
Query: 428 EDACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEE 601
++ +KR + RG +GR DDN E++KKR V + P++++ +N+++ ++ + +
Sbjct: 119 QETMLKRLIHRGKTSGRSDDNIESIKKRFVTYTKASMPVVEYLKSQNRLITIDAEQDPDA 178
Query: 602 VF 607
VF
Sbjct: 179 VF 180
>sp|P39069|KAD1_RAT Adenylate kinase isoenzyme 1 (ATP-AMP transphosphorylase) (AK1)
(Myokinase)
Length = 194
Score = 135 bits (339), Expect = 2e-31
Identities = 71/183 (38%), Positives = 111/183 (60%), Gaps = 4/183 (2%)
Frame = +2
Query: 74 QKFSVTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGDLIKKHMQEG 253
+K + FV+GGPGSGKGTQC I + +GY H+S GDLLR E + +S+ G ++ M++G
Sbjct: 6 KKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSSR-GKMLSSIMEKG 64
Query: 254 SIVPVEITCSLIEKAM--KASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECS 427
+VP+E ++ AM K + FLIDG+PR + + + ++ +LY++
Sbjct: 65 ELVPLETVLDMLRDAMFAKVDSSNGFLIDGYpreVKQGEEFERKIAQPT---LLLYVDAG 121
Query: 428 EDACVKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEE 601
+ +R L RG +GRVDDNEET+KKRL + +P+I +DK V KVN + +++
Sbjct: 122 PETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVISFYDKRGIVRKVNAEGSVDT 181
Query: 602 VFA 610
VF+
Sbjct: 182 VFS 184
>sp|P12115|KAD_CYPCA Adenylate kinase (ATP-AMP transphosphorylase)
Length = 193
Score = 134 bits (336), Expect = 3e-31
Identities = 73/181 (40%), Positives = 112/181 (61%), Gaps = 4/181 (2%)
Frame = +2
Query: 86 VTFVLGGPGSGKGTQCINIAKTFGYLHVSAGDLLREEKDNANSQYGDLIKKHMQEGSIVP 265
+ FV+GGPGSGKGTQC I + +GY H+S+GDLLR E + S+ G ++ MQ+G +VP
Sbjct: 9 IVFVVGGPGSGKGTQCEKIVEKYGYTHLSSGDLLRAEV-ASGSERGKQLQAIMQKGELVP 67
Query: 266 VEITCSLIEKAM--KASGKSKFLIDGFPRNQNNLDGWNKVMSDKVHIETVLYIECSEDAC 439
++ +I+ AM KA +LIDG+PR + + K + +LYI+ +
Sbjct: 68 LDTVLDMIKDAMIAKADVSKGYLIDGYpreVKQGEEFEKKIGAPA---LLLYIDAKAETM 124
Query: 440 VKRCLGRG--TGRVDDNEETLKKRLVQFKSECKPIIDHFDKENKVLKVNGDLTIEEVFAI 613
V+R + RG +GR DDNEET+KKRL + +P+I +++ V K+N +L ++EVFAI
Sbjct: 125 VQRLMKRGQTSGRSDDNEETIKKRLDLYYKATEPVIAYYETRGIVRKINSELPVDEVFAI 184
Query: 614 I 616
+
Sbjct: 185 V 185
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,334,986
Number of Sequences: 369166
Number of extensions: 1678138
Number of successful extensions: 5370
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4789
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5008
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)