Planaria EST Database

DrC_00841

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00841
         (893 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8IZP0|ABI1_HUMAN  Abl-interactor 1 (Abelson interactor 1...    64   6e-10
sp|Q9NYB9|ABI2_HUMAN  Abl-interactor 2 (Abelson interactor 2...    64   6e-10
sp|P62484|ABI2_MOUSE  Abl-interactor 2 (Abelson interactor 2...    64   7e-10
sp|Q8CBW3|ABI1_MOUSE  Abl-interactor 1 (Abelson interactor 1...    62   2e-09
sp|Q9QZM5|ABI1_RAT  Abl-interactor 1 (Abelson interactor 1) ...    62   2e-09
sp|Q9P2A4|ABI3_HUMAN  ABI gene family member 3 (New molecule...    55   2e-07
sp|Q8BYZ1|ABI3_MOUSE  ABI gene family member 3 (New molecule...    48   4e-05
sp|Q9NZM3|ITSN2_HUMAN  Intersectin-2 (SH3 domain-containing ...    44   5e-04
sp|Q9Z0R6|ITSN2_MOUSE  Intersectin-2 (SH3 domain-containing ...    44   5e-04
sp|Q9WVE9|ITSN1_RAT  Intersectin-1 (EH domain and SH3 domain...    37   0.097

>sp|Q8IZP0|ABI1_HUMAN Abl-interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3
           domain-binding protein 1) (Eps8 SH3 domain-binding
           protein) (Eps8-binding protein) (e3B1) (Nap1-binding
           protein) (Nap1BP) (Abl-binding protein 4) (AblBP4)
          Length = 508

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 37/100 (37%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
 Frame = +2

Query: 452 PPPPNVEQFQ-RPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQ 628
           PPP ++  F   PP      +D     Y  +   +      PY      +  D  WAP  
Sbjct: 399 PPPDDIPMFDDSPPPPPPPPVD-----YEDEEAAVVQYND-PY------ADGDPAWAPKN 446

Query: 629 YICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDGRWGG 748
           YI KVV +Y Y ++K+DELSF+E  +IYV +KNDDG + G
Sbjct: 447 YIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEG 486


 Score = 30.4 bits (67), Expect = 7.0
 Identities = 13/17 (76%), Positives = 13/17 (76%)
 Frame = +3

Query: 744 EGVMNGKAGLFPGNYVE 794
           EGV N   GLFPGNYVE
Sbjct: 485 EGVCNRVTGLFPGNYVE 501

>sp|Q9NYB9|ABI2_HUMAN Abl-interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding
           protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
          Length = 513

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 38/99 (38%), Positives = 51/99 (51%)
 Frame = +2

Query: 452 PPPPNVEQFQRPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQY 631
           PPPP VE+   P  +E          Y  +   +      PY      ++ D  WAP  Y
Sbjct: 403 PPPPPVEE---PVFDESPPPPPPPEDYEEEEAAVVEYSD-PY------AEEDPPWAPRSY 452

Query: 632 ICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDGRWGG 748
           + KVV +Y Y ++KEDELSF E  +IYV +KNDDG + G
Sbjct: 453 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEG 491


 Score = 35.8 bits (81), Expect = 0.17
 Identities = 15/17 (88%), Positives = 15/17 (88%)
 Frame = +3

Query: 744 EGVMNGKAGLFPGNYVE 794
           EGVMNG  GLFPGNYVE
Sbjct: 490 EGVMNGVTGLFPGNYVE 506

>sp|P62484|ABI2_MOUSE Abl-interactor 2 (Abelson interactor 2) (Abi-2)
          Length = 446

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 38/99 (38%), Positives = 51/99 (51%)
 Frame = +2

Query: 452 PPPPNVEQFQRPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQY 631
           PPPP VE+   P  +E          Y  +   +      PY      ++ D  WAP  Y
Sbjct: 336 PPPPPVEE---PVFDESPPPPPPPEDYEEEEAAVVEYSD-PY------AEEDPPWAPRAY 385

Query: 632 ICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDGRWGG 748
           + KVV +Y Y ++KEDELSF E  +IYV +KNDDG + G
Sbjct: 386 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEG 424


 Score = 35.8 bits (81), Expect = 0.17
 Identities = 15/17 (88%), Positives = 15/17 (88%)
 Frame = +3

Query: 744 EGVMNGKAGLFPGNYVE 794
           EGVMNG  GLFPGNYVE
Sbjct: 423 EGVMNGVTGLFPGNYVE 439

>sp|Q8CBW3|ABI1_MOUSE Abl-interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3
           domain-binding protein 1) (Eps8 SH3 domain-binding
           protein) (Eps8-binding protein) (e3B1) (Ablphilin-1)
          Length = 481

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
 Frame = +2

Query: 452 PPPPNVEQFQR---PPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAP 622
           PPP ++  F     PP    ++ +  +   +  S         PY      +  D  WAP
Sbjct: 372 PPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYS--------DPY------ADGDPAWAP 417

Query: 623 SQYICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDGRWGG 748
             YI KVV +Y Y ++K+DELSF E  +IYV +KNDDG + G
Sbjct: 418 KNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEG 459


 Score = 30.4 bits (67), Expect = 7.0
 Identities = 13/17 (76%), Positives = 13/17 (76%)
 Frame = +3

Query: 744 EGVMNGKAGLFPGNYVE 794
           EGV N   GLFPGNYVE
Sbjct: 458 EGVCNRVTGLFPGNYVE 474

>sp|Q9QZM5|ABI1_RAT Abl-interactor 1 (Abelson interactor 1) (Abi-1) (Eps8 SH3 domain
           binding protein) (Eps8 binding protein) (e3B1)
          Length = 476

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
 Frame = +2

Query: 452 PPPPNVEQFQR---PPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAP 622
           PPP ++  F     PP    ++ +  +   +  S         PY      +  D  WAP
Sbjct: 367 PPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYS--------DPY------ADGDPAWAP 412

Query: 623 SQYICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDGRWGG 748
             YI KVV +Y Y ++K+DELSF E  +IYV +KNDDG + G
Sbjct: 413 KNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEG 454


 Score = 30.4 bits (67), Expect = 7.0
 Identities = 13/17 (76%), Positives = 13/17 (76%)
 Frame = +3

Query: 744 EGVMNGKAGLFPGNYVE 794
           EGV N   GLFPGNYVE
Sbjct: 453 EGVCNRVTGLFPGNYVE 469

>sp|Q9P2A4|ABI3_HUMAN ABI gene family member 3 (New molecule including SH3) (Nesh)
          Length = 366

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 6/101 (5%)
 Frame = +2

Query: 452 PPPPNVEQFQRPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIK------SQSDEV 613
           PPP  VE FQRPP+ E+++     +  +   + +    P   D L +          +  
Sbjct: 245 PPPAAVEVFQRPPTLEELS-PPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPS 303

Query: 614 WAPSQYICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDG 736
           W P+ Y+ KVVTLY Y   K++ELSF E  +I V ++  DG
Sbjct: 304 WVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDG 344

>sp|Q8BYZ1|ABI3_MOUSE ABI gene family member 3 (New molecule including SH3) (Nesh)
          Length = 367

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 30/96 (31%), Positives = 47/96 (48%)
 Frame = +2

Query: 449 LPPPPNVEQFQRPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQ 628
           LPPPP   +  +PP   ++ +         D +G+    P  +         +  W P+ 
Sbjct: 259 LPPPPL--EVSQPPLEAELPLPPPP-ALEGDELGLLPPPPPGF------GPDEPSWVPAS 309

Query: 629 YICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDG 736
           Y+ KVVTLY Y + K++ELSF E  +I V ++  DG
Sbjct: 310 YLEKVVTLYPYTRQKDNELSFSEGTVICVIRRYSDG 345

>sp|Q9NZM3|ITSN2_HUMAN Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18)
            (SH3P18-like WASP associated protein)
          Length = 1696

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = +2

Query: 572  PYDVLRIKSQSDEVWAPSQY-ICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDGRWGG 748
            P   +++   S E   P+ + +C+V+ +Y Y  N EDELSF + +LI V  K+D   W G
Sbjct: 1107 PASHVKLLGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQG 1166

>sp|Q9Z0R6|ITSN2_MOUSE Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains
            protein 2) (EH domain and SH3 domain regulator of
            endocytosis 2)
          Length = 1658

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
 Frame = +2

Query: 572  PYDVLRIKSQSDEVWAPSQY-ICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDGRWGG 748
            P   +++   S E   P+ + +C+V+ +Y Y+ N EDEL+F + +LI V  K+D   W G
Sbjct: 1068 PASHVKLLGPSSERTMPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQG 1127

>sp|Q9WVE9|ITSN1_RAT Intersectin-1 (EH domain and SH3 domain regulator of endocytosis 1)
          Length = 1217

 Score = 36.6 bits (83), Expect = 0.097
 Identities = 14/39 (35%), Positives = 23/39 (58%)
 Frame = +2

Query: 632  ICKVVTLYKYLQNKEDELSFLENELIYVKQKNDDGRWGG 748
            +C+V+ +Y Y    +DEL+F + ++I V  K D   W G
Sbjct: 1154 VCQVIGMYDYTAQNDDELAFSKGQIINVLSKEDPDWWKG 1192

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,533,283
Number of Sequences: 369166
Number of extensions: 1478142
Number of successful extensions: 4701
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4318
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4691
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00841

  1. Dr_sW_021_H11
  2. Dr_sW_016_B08