Planaria EST Database

DrC_00831

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00831
         (879 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9JMH6|TRXR1_MOUSE  Thioredoxin reductase 1, cytoplasmic ...   264   3e-70
sp|O89049|TRXR1_RAT  Thioredoxin reductase 1, cytoplasmic (T...   259   5e-69
sp|O62768|TRXR1_BOVIN  Thioredoxin reductase 1, cytoplasmic ...   258   2e-68
sp|Q16881|TRXR1_HUMAN  Thioredoxin reductase 1, cytoplasmic ...   254   2e-67
sp|Q9MYY8|TRXR1_PIG  Thioredoxin reductase 1, cytoplasmic (T...   254   2e-67
sp|Q9NNW7|TRXR2_HUMAN  Thioredoxin reductase 2, mitochondria...   215   1e-55
sp|Q17745|TRXR_CAEEL  Thioredoxin reductase (TR-Se) (TRR)         213   6e-55
sp|Q9Z0J5|TRXR2_RAT  Thioredoxin reductase 2, mitochondrial ...   213   7e-55
sp|Q9JLT4|TRXR2_MOUSE  Thioredoxin reductase 2, mitochondria...   212   1e-54
sp|P91938|TRXR1_DROME  Thioredoxin reductase 1, mitochondria...   200   4e-51

>sp|Q9JMH6|TRXR1_MOUSE Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
          Length = 499

 Score =  264 bits (674), Expect = 3e-70
 Identities = 125/200 (62%), Positives = 153/200 (76%), Gaps = 1/200 (0%)
 Frame = +1

Query: 7   IGLDNINLDL-DKNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYG 183
           IGL+ + + + +K G++ VT+EEQTNV  +YAIGDI+ G L+LTPVAIQAG+ LA+RLYG
Sbjct: 300 IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYG 359

Query: 184 GERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSDN 363
           G  V  DY NVPTTVFTPLEYGC G  EE A+ K+G ENIEV+H  F PLEWTV  R +N
Sbjct: 360 GSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNN 419

Query: 364 DCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSETF 543
            CY K+ICN  D+ RV+G HVLGPNAGE+TQG+A A++ G TK+  D TIGIHP C+E F
Sbjct: 420 KCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIF 479

Query: 544 TTLNITKSSGVDPAQSGC*G 603
           TTL++TK SG D  QSGC G
Sbjct: 480 TTLSVTKRSGGDILQSGCCG 499

>sp|O89049|TRXR1_RAT Thioredoxin reductase 1, cytoplasmic (TR) (TR1) (NADPH-dependent
           thioredoxin reductase)
          Length = 498

 Score =  259 bits (663), Expect = 5e-69
 Identities = 126/200 (63%), Positives = 152/200 (76%), Gaps = 1/200 (0%)
 Frame = +1

Query: 7   IGLDNINLDL-DKNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYG 183
           IGL+ + + + +K G++ VT+EEQTNV  +YAIGDI+ G L+LTPVAIQAG+ LA+RLYG
Sbjct: 300 IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYG 359

Query: 184 GERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSDN 363
           G  V  DY NVPTTVFTPLEYGC G  EE A+ K+G ENIEV+H  F PLEWTV  R +N
Sbjct: 360 GSTVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNN 419

Query: 364 DCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSETF 543
            CY K+ICN  DN RV+G HVLGPNAGE+TQG+A A + G TK+  D TIGIHP C+E F
Sbjct: 420 KCYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAA-KCGLTKQQLDSTIGIHPVCAEIF 478

Query: 544 TTLNITKSSGVDPAQSGC*G 603
           TTL++TK SG D  QSGC G
Sbjct: 479 TTLSVTKRSGGDILQSGCCG 498

>sp|O62768|TRXR1_BOVIN Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
          Length = 499

 Score =  258 bits (659), Expect = 2e-68
 Identities = 121/200 (60%), Positives = 151/200 (75%), Gaps = 1/200 (0%)
 Frame = +1

Query: 7   IGLDNINLDL-DKNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYG 183
           IGL+N+ + + +K G++ VT EEQTNV  +YAIGDI+ G L+LTPVAIQAG+ LA+RLYG
Sbjct: 300 IGLENVGVKINEKTGKIPVTEEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYG 359

Query: 184 GERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSDN 363
           G  V  DY NVPTTVFTPLEYG  G  EE A+ K+G EN+EV+H  F PLEWT+  R +N
Sbjct: 360 GSTVKCDYENVPTTVFTPLEYGSCGLSEEKAVEKFGEENVEVYHSYFWPLEWTIPSRDNN 419

Query: 364 DCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSETF 543
            CY K++CN  DN RV+G HVLGPNAGE+TQG+A A++ G TK   D TIGIHP C+E F
Sbjct: 420 KCYAKVVCNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKDQLDSTIGIHPVCAEVF 479

Query: 544 TTLNITKSSGVDPAQSGC*G 603
           TTL++TK SG +  Q+GC G
Sbjct: 480 TTLSVTKRSGGNILQTGCCG 499

>sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic precursor (TR) (TR1)
          Length = 499

 Score =  254 bits (650), Expect = 2e-67
 Identities = 119/200 (59%), Positives = 149/200 (74%), Gaps = 1/200 (0%)
 Frame = +1

Query: 7   IGLDNINLDL-DKNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYG 183
           IGL+ + + + +K G++ VT+EEQTNV  +YAIGDI+   ++LTPVAIQAG+ LA+RLY 
Sbjct: 300 IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYA 359

Query: 184 GERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSDN 363
           G  V  DY NVPTTVFTPLEYG  G  EE A+ K+G ENIEV+H  F PLEWT+  R +N
Sbjct: 360 GSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNN 419

Query: 364 DCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSETF 543
            CY K+ICN  DN RV+G HVLGPNAGE+TQG+A A++ G TK+  D TIGIHP C+E F
Sbjct: 420 KCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVF 479

Query: 544 TTLNITKSSGVDPAQSGC*G 603
           TTL++TK SG    Q+GC G
Sbjct: 480 TTLSVTKRSGASILQAGCCG 499

>sp|Q9MYY8|TRXR1_PIG Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
          Length = 499

 Score =  254 bits (650), Expect = 2e-67
 Identities = 119/200 (59%), Positives = 149/200 (74%), Gaps = 1/200 (0%)
 Frame = +1

Query: 7   IGLDNINLDL-DKNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYG 183
           IGL+ + + + +K G++ VT+EEQTNV  +YAIGDI+   ++LTPVAIQAG+ LA+RLY 
Sbjct: 300 IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYA 359

Query: 184 GERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSDN 363
           G  V  DY NVPTTVFTPLEYG  G  EE A+ K+G ENIEV+H  F PLEWT+  R +N
Sbjct: 360 GSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNN 419

Query: 364 DCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSETF 543
            CY K+ICN  DN RV+G HVLGPNAGE+TQG+A A++ G TK+  D TIGIHP C+E F
Sbjct: 420 KCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVF 479

Query: 544 TTLNITKSSGVDPAQSGC*G 603
           TTL++TK SG    Q+GC G
Sbjct: 480 TTLSVTKRSGASILQAGCCG 499

>sp|Q9NNW7|TRXR2_HUMAN Thioredoxin reductase 2, mitochondrial precursor (TR3) (TR-beta)
           (Selenoprotein Z) (SelZ)
          Length = 524

 Score =  215 bits (547), Expect = 1e-55
 Identities = 101/204 (49%), Positives = 144/204 (70%), Gaps = 8/204 (3%)
 Frame = +1

Query: 16  DNINLDLDKNG--------RVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLAR 171
           D  +L+L+K G        ++ V + E T+V ++YAIGD++ G  +LTP+AI AG+ L +
Sbjct: 321 DTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQ 380

Query: 172 RLYGGERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAH 351
           RL+GG   L DY NVPTTVFTPLEYGC+G  EE+A++++G E++EV+H ++KPLE+TVA 
Sbjct: 381 RLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAG 440

Query: 352 RSDNDCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTC 531
           R  + CY K++C +     V+GLH LGPNAGE+TQG+A+ ++ GA+      T+GIHPTC
Sbjct: 441 RDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTC 500

Query: 532 SETFTTLNITKSSGVDPAQSGC*G 603
           SE    L I+K SG+DP  +GC G
Sbjct: 501 SEEVVKLRISKRSGLDPTVTGCCG 524

>sp|Q17745|TRXR_CAEEL Thioredoxin reductase (TR-Se) (TRR)
          Length = 667

 Score =  213 bits (542), Expect = 6e-55
 Identities = 102/202 (50%), Positives = 141/202 (69%), Gaps = 2/202 (0%)
 Frame = +1

Query: 4    NIGLDNINLDLDKNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYG 183
            ++GL  I ++  K+ +V    E+ T +  VYAIGD++ G  +LTPVAIQAG+ L RR++ 
Sbjct: 466  DVGLTTIGVERAKSKKVLGRREQSTTIPWVYAIGDVLEGTPELTPVAIQAGRVLMRRIFD 525

Query: 184  GERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSDN 363
            G   LT+Y  +PTTVFTPLEYGC G  EEDA+ KYG +NI ++H  F PLE+T++ R D 
Sbjct: 526  GANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLEYTISERMDK 585

Query: 364  D-CYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSET 540
            D CY K+IC +++  +V+G H+L PNAGE+TQG+ +A+++ A K DFD  IGIHPT +E 
Sbjct: 586  DHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALKLAAKKADFDRLIGIHPTVAEN 645

Query: 541  FTTLNITKSSGVDPAQ-SGC*G 603
            FTTL + K  G +  Q SGC G
Sbjct: 646  FTTLTLEKKEGDEELQASGCCG 667

>sp|Q9Z0J5|TRXR2_RAT Thioredoxin reductase 2, mitochondrial precursor (TR3)
          Length = 526

 Score =  213 bits (541), Expect = 7e-55
 Identities = 101/201 (50%), Positives = 143/201 (71%), Gaps = 1/201 (0%)
 Frame = +1

Query: 4   NIGLDNINLDLD-KNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLY 180
           N+ L+   ++ + KN ++ V  +E T+V ++YAIGD+  G  +LTP AI+AGK LA+RL+
Sbjct: 326 NLNLEKAGVNTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLF 385

Query: 181 GGERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSD 360
           G    L +Y NVPTTVFTPLEYGC+G  EE+A++ +G E+IEV+H  +KPLE+TVA R  
Sbjct: 386 GKSSTLMNYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHIEVYHAYYKPLEFTVADRDA 445

Query: 361 NDCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSET 540
           + CY K++C +     V+GLH LGPNAGE+TQG+A+ ++ GA+      T+GIHPTCSE 
Sbjct: 446 SQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIQCGASYAQVMQTVGIHPTCSEE 505

Query: 541 FTTLNITKSSGVDPAQSGC*G 603
              L+I+K SG+DP  +GC G
Sbjct: 506 VVKLHISKRSGLDPTVTGCCG 526

>sp|Q9JLT4|TRXR2_MOUSE Thioredoxin reductase 2, mitochondrial precursor (TR3)
          Length = 524

 Score =  212 bits (539), Expect = 1e-54
 Identities = 98/188 (52%), Positives = 136/188 (72%)
 Frame = +1

Query: 40  KNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYGGERVLTDYINVP 219
           KN ++ V  +E T+V ++YAIGD+  G  +LTP AI+AGK LA+RL+G    L DY NVP
Sbjct: 337 KNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNVP 396

Query: 220 TTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSDNDCYGKLICNKSD 399
           TTVFTPLEYGC+G  EE+A++ +G E++EV+H  +KPLE+TVA R  + CY K++C +  
Sbjct: 397 TTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMREP 456

Query: 400 NMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSETFTTLNITKSSGVD 579
              V+GLH LGPNAGE+TQG+A+ ++ GA+      T+GIHPTCSE    L+I+K SG++
Sbjct: 457 PQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLE 516

Query: 580 PAQSGC*G 603
           P  +GC G
Sbjct: 517 PTVTGCCG 524

>sp|P91938|TRXR1_DROME Thioredoxin reductase 1, mitochondrial precursor (TrxR-1)
          Length = 596

 Score =  200 bits (509), Expect = 4e-51
 Identities = 97/198 (48%), Positives = 134/198 (67%)
 Frame = +1

Query: 4   NIGLDNINLDLDKNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYG 183
           ++ L N  + + K+ ++ V ++E TNV N+YA+GDII G  +LTPVA+ AG+ LARRLYG
Sbjct: 398 DLNLPNAGVTVQKD-KIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYG 456

Query: 184 GERVLTDYINVPTTVFTPLEYGCIGWPEEDAISKYGAENIEVFHQNFKPLEWTVAHRSDN 363
           G     DY +V TTVFTPLEY C+G  EEDA+ ++GA+ IEVFH  +KP E+ +  +S  
Sbjct: 457 GSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVR 516

Query: 364 DCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSETF 543
            CY K +  +  + RV GLH +GP AGE+ QG+A A++ G T     +T+GIHPT +E F
Sbjct: 517 YCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEF 576

Query: 544 TTLNITKSSGVDPAQSGC 597
           T L ITK SG+DP  + C
Sbjct: 577 TRLAITKRSGLDPTPASC 594

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,144,228
Number of Sequences: 369166
Number of extensions: 2109974
Number of successful extensions: 5128
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4846
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4984
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8742211660
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00831

  1. Dr_sW_021_C20
  2. Dr_sW_011_N11