Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00826 (845 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P13230|GRP33_ARTSA Glycine-rich protein GRP33 125 1e-28 sp|Q07666|SAM68_HUMAN KH domain containing, RNA binding, si... 122 2e-27 sp|Q60749|SAM68_MOUSE KH domain containing, RNA binding, si... 119 8e-27 sp|Q91V33|SAM68_RAT KH domain containing, RNA binding, sign... 119 8e-27 sp|Q8UUW7|SAM68_CHICK KH domain containing, RNA binding, si... 119 1e-26 sp|Q17339|GLD1_CAEEL Female germline-specific tumor suppres... 85 2e-16 sp|O01367|HOW_DROME Held out wings protein (KH-domain prote... 76 1e-13 sp|Q15637|SF01_HUMAN Splicing factor 1 (Zinc finger protein... 47 9e-05 sp|Q64213|SF01_MOUSE Splicing factor 1 (Zinc finger protein... 46 1e-04 sp|Q91WJ8|FUBP1_MOUSE Far upstream element-binding protein ... 36 0.15
>sp|P13230|GRP33_ARTSA Glycine-rich protein GRP33 Length = 308 Score = 125 bits (315), Expect = 1e-28 Identities = 55/113 (48%), Positives = 89/113 (78%) Frame = +3 Query: 147 IDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRN 326 +D+ ++ KVK+ ++ PV+Q+P NF GK++GPGG T+K+LQ++T T++S+LG GSMR+ Sbjct: 64 MDLYNDTKVKLVSRCCLPVDQFPKYNFLGKLLGPGGSTMKQLQDETMTKISILGRGSMRD 123 Query: 327 QSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKISKALVEIKKALTPD 485 ++KE EL +GD KY HLNE++H+++ +A P+EAH +++ AL EIKK +TP+ Sbjct: 124 RNKEEELRNSGDVKYAHLNEQLHIEIISIASPAEAHARMAYALTEIKKYITPE 176
>sp|Q07666|SAM68_HUMAN KH domain containing, RNA binding, signal transduction associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68) Length = 443 Score = 122 bits (305), Expect = 2e-27 Identities = 65/146 (44%), Positives = 96/146 (65%), Gaps = 3/146 (2%) Frame = +3 Query: 147 IDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRN 326 +D+ S+K +K++ ++ PV+QYP NF GKI+GP G T+K LQE+T ++SVLG GSMR+ Sbjct: 146 LDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRD 205 Query: 327 QSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKISKALVEIKKALTPD-PSEIQQ 503 ++KE EL + GDPKY HLN +H+ ++ P EA+ ++ A+ E+KK L PD +I Q Sbjct: 206 KAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQ 265 Query: 504 PPGPLSWNEISYQQSV--AGRGRGLP 575 + E+SY V RGRG+P Sbjct: 266 E----QFLELSYLNGVPEPSRGRGVP 287
>sp|Q60749|SAM68_MOUSE KH domain containing, RNA binding, signal transduction associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68) Length = 443 Score = 119 bits (299), Expect = 8e-27 Identities = 67/166 (40%), Positives = 105/166 (63%), Gaps = 9/166 (5%) Frame = +3 Query: 102 IRMEIRRLREGVI------DTIDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTL 263 + +EI ++++G + +D+ S+K +K++ ++ PV+QYP NF GKI+GP G T+ Sbjct: 125 LSVEIEKIQKGESKKDDEENYLDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTI 184 Query: 264 KELQEQTETRMSVLGAGSMRNQSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKI 443 K LQE+T ++SVLG GSMR+++KE EL + GDPKY HLN +H+ ++ P EA+ + Sbjct: 185 KRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALM 244 Query: 444 SKALVEIKKALTPD-PSEIQQPPGPLSWNEISYQQSV--AGRGRGL 572 + A+ E+KK L PD +I Q + E+SY V RGRG+ Sbjct: 245 AHAMEEVKKFLVPDMMDDICQE----QFLELSYLNGVPEPSRGRGV 286
>sp|Q91V33|SAM68_RAT KH domain containing, RNA binding, signal transduction associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68) Length = 443 Score = 119 bits (299), Expect = 8e-27 Identities = 67/166 (40%), Positives = 105/166 (63%), Gaps = 9/166 (5%) Frame = +3 Query: 102 IRMEIRRLREGVI------DTIDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTL 263 + +EI ++++G + +D+ S+K +K++ ++ PV+QYP NF GKI+GP G T+ Sbjct: 125 LSVEIEKIQKGESKKDDEENYLDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTI 184 Query: 264 KELQEQTETRMSVLGAGSMRNQSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKI 443 K LQE+T ++SVLG GSMR+++KE EL + GDPKY HLN +H+ ++ P EA+ + Sbjct: 185 KRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALM 244 Query: 444 SKALVEIKKALTPD-PSEIQQPPGPLSWNEISYQQSV--AGRGRGL 572 + A+ E+KK L PD +I Q + E+SY V RGRG+ Sbjct: 245 AHAMEEVKKFLVPDMMDDICQE----QFLELSYLNGVPEPSRGRGV 286
>sp|Q8UUW7|SAM68_CHICK KH domain containing, RNA binding, signal transduction associated protein 1 (Src-associated in mitosis 68 kDa protein) (Sam68) Length = 433 Score = 119 bits (298), Expect = 1e-26 Identities = 65/146 (44%), Positives = 95/146 (65%), Gaps = 3/146 (2%) Frame = +3 Query: 147 IDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRN 326 +D+ S+K +K++ ++ PV+QYP NF GKI+GP G T+K LQE+T ++SVLG GSMR+ Sbjct: 129 LDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRD 188 Query: 327 QSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKISKALVEIKKALTPD-PSEIQQ 503 ++KE EL + GDPKY HLN +H+ ++ P EA+ ++ A+ E+KK L PD +I Q Sbjct: 189 KAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQ 248 Query: 504 PPGPLSWNEISYQQSV--AGRGRGLP 575 + E+SY V RGRG P Sbjct: 249 E----QFLELSYLNGVPEPTRGRGGP 270
>sp|Q17339|GLD1_CAEEL Female germline-specific tumor suppressor gld-1 (Defective in germ line development protein 1) Length = 463 Score = 85.1 bits (209), Expect = 2e-16 Identities = 51/153 (33%), Positives = 79/153 (51%), Gaps = 6/153 (3%) Frame = +3 Query: 48 EQELLTIDAVTCPNVHSQIRMEIRRLREGVIDT------IDMLSNKKVKIRAKIDFPVEQ 209 E++ LT+ NV + EI R+R + T + + + I KI P + Sbjct: 156 EKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNE 215 Query: 210 YPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRNQSKEMELIQTGDPKYQHLNER 389 YP NF G+I+GP G T K+L++ T ++ V G GSMR++SKE G ++HL + Sbjct: 216 YPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKES--AHRGKANWEHLEDD 273 Query: 390 MHLQVDCLALPSEAHDKISKALVEIKKALTPDP 488 +H+ V C + H K+ AL ++KK L P P Sbjct: 274 LHVLVQCEDTENRVHIKLQAALEQVKKLLIPAP 306
>sp|O01367|HOW_DROME Held out wings protein (KH-domain protein KH93F) (Putative RNA-binding protein) (Muscle-specific protein) (Wings held out protein) (Struthio protein) (Quaking-related 93F) Length = 405 Score = 75.9 bits (185), Expect = 1e-13 Identities = 44/146 (30%), Positives = 77/146 (52%), Gaps = 13/146 (8%) Frame = +3 Query: 84 PNVHSQIRM----EIRRLREGVID---------TIDMLSNKKVKIRAKIDFPVEQYPGVN 224 PNV + + EI R+R + T+ V + K+ PV ++P N Sbjct: 93 PNVFTHVERLLDEEIARVRASLFQINGVKKEPLTLPEPEGSVVTMNEKVYVPVREHPDFN 152 Query: 225 FPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRNQSKEMELIQTGDPKYQHLNERMHLQV 404 F G+I+GP G T K+L+++T ++ V G GSMR++ KE G P ++HL++ +H+ + Sbjct: 153 FVGRILGPRGMTAKQLEQETGCKIMVRGKGSMRDKKKED--ANRGKPNWEHLSDDLHVLI 210 Query: 405 DCLALPSEAHDKISKALVEIKKALTP 482 + A K+++A+ E++K L P Sbjct: 211 TVEDTENRATVKLAQAVAEVQKLLVP 236
>sp|Q15637|SF01_HUMAN Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point binding protein mBBP) (BBP) Length = 639 Score = 46.6 bits (109), Expect = 9e-05 Identities = 17/50 (34%), Positives = 33/50 (66%) Frame = +3 Query: 174 KIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMR 323 ++ K+ P ++YP +NF G +IGP G TLK ++++ ++ + G GS++ Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVK 184
>sp|Q64213|SF01_MOUSE Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point binding protein mBBP) (BBP) (CW17) Length = 653 Score = 45.8 bits (107), Expect = 1e-04 Identities = 17/49 (34%), Positives = 32/49 (65%) Frame = +3 Query: 174 KIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSM 320 ++ K+ P ++YP +NF G +IGP G TLK ++++ ++ + G GS+ Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV 183
>sp|Q91WJ8|FUBP1_MOUSE Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) Length = 651 Score = 35.8 bits (81), Expect = 0.15 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Frame = +3 Query: 231 GKIIGPGGKTLKELQEQTETRMSVLGAGSMRNQSKEMELIQTGDP-KYQHLNE 386 G +IG GG+T+K+LQE+ +M ++ G +N + L TGDP K Q E Sbjct: 194 GLVIGKGGETIKQLQERAGVKMVMIQDGP-QNTGADKPLRITGDPYKVQQAKE 245
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,633,899 Number of Sequences: 369166 Number of extensions: 1687376 Number of successful extensions: 4121 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3996 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4116 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8293644780 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)