Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_E13
(835 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P13230|GRP33_ARTSA Glycine-rich protein GRP33 125 1e-28
sp|Q07666|SAM68_HUMAN KH domain containing, RNA binding, si... 122 2e-27
sp|Q60749|SAM68_MOUSE KH domain containing, RNA binding, si... 119 8e-27
sp|Q91V33|SAM68_RAT KH domain containing, RNA binding, sign... 119 8e-27
sp|Q8UUW7|SAM68_CHICK KH domain containing, RNA binding, si... 119 1e-26
sp|Q17339|GLD1_CAEEL Female germline-specific tumor suppres... 85 2e-16
sp|O01367|HOW_DROME Held out wings protein (KH-domain prote... 76 1e-13
sp|Q15637|SF01_HUMAN Splicing factor 1 (Zinc finger protein... 47 8e-05
sp|Q64213|SF01_MOUSE Splicing factor 1 (Zinc finger protein... 46 1e-04
sp|Q91WJ8|FUBP1_MOUSE Far upstream element-binding protein ... 36 0.15
>sp|P13230|GRP33_ARTSA Glycine-rich protein GRP33
Length = 308
Score = 125 bits (315), Expect = 1e-28
Identities = 55/113 (48%), Positives = 89/113 (78%)
Frame = +2
Query: 137 IDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRN 316
+D+ ++ KVK+ ++ PV+Q+P NF GK++GPGG T+K+LQ++T T++S+LG GSMR+
Sbjct: 64 MDLYNDTKVKLVSRCCLPVDQFPKYNFLGKLLGPGGSTMKQLQDETMTKISILGRGSMRD 123
Query: 317 QSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKISKALVEIKKALTPD 475
++KE EL +GD KY HLNE++H+++ +A P+EAH +++ AL EIKK +TP+
Sbjct: 124 RNKEEELRNSGDVKYAHLNEQLHIEIISIASPAEAHARMAYALTEIKKYITPE 176
>sp|Q07666|SAM68_HUMAN KH domain containing, RNA binding, signal transduction associated
protein 1 (p21 Ras GTPase-activating protein-associated
p62) (GAP-associated tyrosine phosphoprotein p62)
(Src-associated in mitosis 68 kDa protein) (Sam68) (p68)
Length = 443
Score = 122 bits (305), Expect = 2e-27
Identities = 65/146 (44%), Positives = 96/146 (65%), Gaps = 3/146 (2%)
Frame = +2
Query: 137 IDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRN 316
+D+ S+K +K++ ++ PV+QYP NF GKI+GP G T+K LQE+T ++SVLG GSMR+
Sbjct: 146 LDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRD 205
Query: 317 QSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKISKALVEIKKALTPD-PSEIQQ 493
++KE EL + GDPKY HLN +H+ ++ P EA+ ++ A+ E+KK L PD +I Q
Sbjct: 206 KAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQ 265
Query: 494 PPGPLSWNEISYQQSV--AGRGRGLP 565
+ E+SY V RGRG+P
Sbjct: 266 E----QFLELSYLNGVPEPSRGRGVP 287
>sp|Q60749|SAM68_MOUSE KH domain containing, RNA binding, signal transduction associated
protein 1 (p21 Ras GTPase-activating protein-associated
p62) (GAP-associated tyrosine phosphoprotein p62)
(Src-associated in mitosis 68 kDa protein) (Sam68) (p68)
Length = 443
Score = 119 bits (299), Expect = 8e-27
Identities = 67/166 (40%), Positives = 105/166 (63%), Gaps = 9/166 (5%)
Frame = +2
Query: 92 IRMEIRRLREGVI------DTIDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTL 253
+ +EI ++++G + +D+ S+K +K++ ++ PV+QYP NF GKI+GP G T+
Sbjct: 125 LSVEIEKIQKGESKKDDEENYLDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTI 184
Query: 254 KELQEQTETRMSVLGAGSMRNQSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKI 433
K LQE+T ++SVLG GSMR+++KE EL + GDPKY HLN +H+ ++ P EA+ +
Sbjct: 185 KRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALM 244
Query: 434 SKALVEIKKALTPD-PSEIQQPPGPLSWNEISYQQSV--AGRGRGL 562
+ A+ E+KK L PD +I Q + E+SY V RGRG+
Sbjct: 245 AHAMEEVKKFLVPDMMDDICQE----QFLELSYLNGVPEPSRGRGV 286
>sp|Q91V33|SAM68_RAT KH domain containing, RNA binding, signal transduction associated
protein 1 (p21 Ras GTPase-activating protein-associated
p62) (GAP-associated tyrosine phosphoprotein p62)
(Src-associated in mitosis 68 kDa protein) (Sam68) (p68)
Length = 443
Score = 119 bits (299), Expect = 8e-27
Identities = 67/166 (40%), Positives = 105/166 (63%), Gaps = 9/166 (5%)
Frame = +2
Query: 92 IRMEIRRLREGVI------DTIDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTL 253
+ +EI ++++G + +D+ S+K +K++ ++ PV+QYP NF GKI+GP G T+
Sbjct: 125 LSVEIEKIQKGESKKDDEENYLDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTI 184
Query: 254 KELQEQTETRMSVLGAGSMRNQSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKI 433
K LQE+T ++SVLG GSMR+++KE EL + GDPKY HLN +H+ ++ P EA+ +
Sbjct: 185 KRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALM 244
Query: 434 SKALVEIKKALTPD-PSEIQQPPGPLSWNEISYQQSV--AGRGRGL 562
+ A+ E+KK L PD +I Q + E+SY V RGRG+
Sbjct: 245 AHAMEEVKKFLVPDMMDDICQE----QFLELSYLNGVPEPSRGRGV 286
>sp|Q8UUW7|SAM68_CHICK KH domain containing, RNA binding, signal transduction associated
protein 1 (Src-associated in mitosis 68 kDa protein)
(Sam68)
Length = 433
Score = 119 bits (298), Expect = 1e-26
Identities = 65/146 (44%), Positives = 95/146 (65%), Gaps = 3/146 (2%)
Frame = +2
Query: 137 IDMLSNKKVKIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRN 316
+D+ S+K +K++ ++ PV+QYP NF GKI+GP G T+K LQE+T ++SVLG GSMR+
Sbjct: 129 LDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRD 188
Query: 317 QSKEMELIQTGDPKYQHLNERMHLQVDCLALPSEAHDKISKALVEIKKALTPD-PSEIQQ 493
++KE EL + GDPKY HLN +H+ ++ P EA+ ++ A+ E+KK L PD +I Q
Sbjct: 189 KAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQ 248
Query: 494 PPGPLSWNEISYQQSV--AGRGRGLP 565
+ E+SY V RGRG P
Sbjct: 249 E----QFLELSYLNGVPEPTRGRGGP 270
>sp|Q17339|GLD1_CAEEL Female germline-specific tumor suppressor gld-1 (Defective in germ
line development protein 1)
Length = 463
Score = 85.1 bits (209), Expect = 2e-16
Identities = 51/153 (33%), Positives = 79/153 (51%), Gaps = 6/153 (3%)
Frame = +2
Query: 38 EQELLTIDAVTCPNVHSQIRMEIRRLREGVIDT------IDMLSNKKVKIRAKIDFPVEQ 199
E++ LT+ NV + EI R+R + T + + + I KI P +
Sbjct: 156 EKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNE 215
Query: 200 YPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRNQSKEMELIQTGDPKYQHLNER 379
YP NF G+I+GP G T K+L++ T ++ V G GSMR++SKE G ++HL +
Sbjct: 216 YPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKES--AHRGKANWEHLEDD 273
Query: 380 MHLQVDCLALPSEAHDKISKALVEIKKALTPDP 478
+H+ V C + H K+ AL ++KK L P P
Sbjct: 274 LHVLVQCEDTENRVHIKLQAALEQVKKLLIPAP 306
>sp|O01367|HOW_DROME Held out wings protein (KH-domain protein KH93F) (Putative
RNA-binding protein) (Muscle-specific protein) (Wings
held out protein) (Struthio protein) (Quaking-related
93F)
Length = 405
Score = 75.9 bits (185), Expect = 1e-13
Identities = 44/146 (30%), Positives = 77/146 (52%), Gaps = 13/146 (8%)
Frame = +2
Query: 74 PNVHSQIRM----EIRRLREGVID---------TIDMLSNKKVKIRAKIDFPVEQYPGVN 214
PNV + + EI R+R + T+ V + K+ PV ++P N
Sbjct: 93 PNVFTHVERLLDEEIARVRASLFQINGVKKEPLTLPEPEGSVVTMNEKVYVPVREHPDFN 152
Query: 215 FPGKIIGPGGKTLKELQEQTETRMSVLGAGSMRNQSKEMELIQTGDPKYQHLNERMHLQV 394
F G+I+GP G T K+L+++T ++ V G GSMR++ KE G P ++HL++ +H+ +
Sbjct: 153 FVGRILGPRGMTAKQLEQETGCKIMVRGKGSMRDKKKED--ANRGKPNWEHLSDDLHVLI 210
Query: 395 DCLALPSEAHDKISKALVEIKKALTP 472
+ A K+++A+ E++K L P
Sbjct: 211 TVEDTENRATVKLAQAVAEVQKLLVP 236
>sp|Q15637|SF01_HUMAN Splicing factor 1 (Zinc finger protein 162) (Transcription factor
ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch
point binding protein mBBP) (BBP)
Length = 639
Score = 46.6 bits (109), Expect = 8e-05
Identities = 17/50 (34%), Positives = 33/50 (66%)
Frame = +2
Query: 164 KIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSMR 313
++ K+ P ++YP +NF G +IGP G TLK ++++ ++ + G GS++
Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVK 184
>sp|Q64213|SF01_MOUSE Splicing factor 1 (Zinc finger protein 162) (Transcription factor
ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian
branch point binding protein mBBP) (BBP) (CW17)
Length = 653
Score = 45.8 bits (107), Expect = 1e-04
Identities = 17/49 (34%), Positives = 32/49 (65%)
Frame = +2
Query: 164 KIRAKIDFPVEQYPGVNFPGKIIGPGGKTLKELQEQTETRMSVLGAGSM 310
++ K+ P ++YP +NF G +IGP G TLK ++++ ++ + G GS+
Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV 183
>sp|Q91WJ8|FUBP1_MOUSE Far upstream element-binding protein 1 (FUSE-binding protein 1)
(FBP)
Length = 651
Score = 35.8 bits (81), Expect = 0.15
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Frame = +2
Query: 221 GKIIGPGGKTLKELQEQTETRMSVLGAGSMRNQSKEMELIQTGDP-KYQHLNE 376
G +IG GG+T+K+LQE+ +M ++ G +N + L TGDP K Q E
Sbjct: 194 GLVIGKGGETIKQLQERAGVKMVMIQDGP-QNTGADKPLRITGDPYKVQQAKE 245
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,661,192
Number of Sequences: 369166
Number of extensions: 1668171
Number of successful extensions: 4062
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3940
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4057
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8100769320
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)