Planaria EST Database

DrC_00822

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00822
         (927 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9BW91|NUDT9_HUMAN  ADP-ribose pyrophosphatase, mitochond...   295   2e-79
sp|Q8BVU5|NUDT9_MOUSE  ADP-ribose pyrophosphatase, mitochond...   293   5e-79
sp|Q5XIG0|NUDT9_RAT  ADP-ribose pyrophosphatase, mitochondri...   293   5e-79
sp|Q09297|NDX6_CAEEL  Putative nudix hydrolase 6                  208   2e-53
sp|Q91YD4|TRPM2_MOUSE  Transient receptor potential cation c...   193   5e-49
sp|O94759|TRPM2_HUMAN  Transient receptor potential cation c...   188   2e-47
sp|Q8N2Z3|NUD9P_HUMAN  Hypothetical nucleoside diphosphate-l...   121   3e-27
sp|P34641|CED11_CAEEL  Ced-11 protein                              48   4e-05
sp|Q58549|ADPP_METJA  ADP-ribose pyrophosphatase (ADP-ribose...    40   0.009
sp|P35942|RRPO_ROTGI  RNA-directed RNA polymerase subunit VP...    38   0.035

>sp|Q9BW91|NUDT9_HUMAN ADP-ribose pyrophosphatase, mitochondrial precursor (ADP-ribose
           diphosphatase) (Adenosine diphosphoribose
           pyrophosphatase) (ADPR-PPase) (ADP-ribose
           phosphohydrolase) (Nucleoside diphosphate-linked moiety
           X motif 9) (Nudix motif 9)
          Length = 350

 Score =  295 bits (754), Expect = 2e-79
 Identities = 143/279 (51%), Positives = 190/279 (68%), Gaps = 1/279 (0%)
 Frame = +2

Query: 23  HIRCREEFYpreKNIKRFHVSDEYVPWTVDFPEYEPTIYTSNKILTSNLTDDDILKNPFA 202
           H + R   YP  K ++R  V +E V W V++ +Y+P  YT+  +L      D  +     
Sbjct: 62  HNKARTSPYPGSK-VERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNF 120

Query: 203 DINFNELDGKIDRRSHHGMYDIVDGLPRNPYGRTGIVGRGCLYYWGPNHAADPVVTTWKR 382
              FNE DG ++R+S +G+Y+I +G PRNP GRTG+VGRG L  WGPNHAADP++T WKR
Sbjct: 121 SPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKR 180

Query: 383 DENNEIIFDKVSQKPILKFVGIFRKHDNEWALPGGMVDPGELVTATIKREFSEEALNTLI 562
           D +   I   VS K IL+FV I RK   EWA+PGGMVDPGE ++AT+KREF EEALN+L 
Sbjct: 181 DSSGNKIMHPVSGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQ 240

Query: 563 KTTQEKKELYEKIDYLF-VNGTTIYTGYVDDPRNTDNAWIETVAVNFHDKDGDSLAQIKL 739
           KT+ EK+E+ EK+  LF  +   IY GYVDDPRNTDNAW+ET AVN+HD+ G+ +  + L
Sbjct: 241 KTSAEKREIEEKLHKLFSQDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLML 300

Query: 740 EAGDDAAAIRWIDLNKELKLYASHLSILSDLVDKHGAHW 856
           EAGDDA  ++W+D+N +LKLYASH   +  + +K  AHW
Sbjct: 301 EAGDDAGKVKWVDINDKLKLYASHSQFIKLVAEKRDAHW 339

>sp|Q8BVU5|NUDT9_MOUSE ADP-ribose pyrophosphatase, mitochondrial precursor (ADP-ribose
           diphosphatase) (Adenosine diphosphoribose
           pyrophosphatase) (ADPR-PPase) (ADP-ribose
           phosphohydrolase) (Nucleoside diphosphate-linked moiety
           X motif 9) (Nudix motif 9)
          Length = 350

 Score =  293 bits (750), Expect = 5e-79
 Identities = 142/279 (50%), Positives = 190/279 (68%), Gaps = 1/279 (0%)
 Frame = +2

Query: 23  HIRCREEFYpreKNIKRFHVSDEYVPWTVDFPEYEPTIYTSNKILTSNLTDDDILKNPFA 202
           H + R   YP  K ++R  V +E V W V++ +Y P  YT+  +L      D  +     
Sbjct: 62  HNKARTSPYPGSK-VERSQVPNEKVGWLVEWQDYNPVEYTAVSVLAGPQWADPQISESNF 120

Query: 203 DINFNELDGKIDRRSHHGMYDIVDGLPRNPYGRTGIVGRGCLYYWGPNHAADPVVTTWKR 382
              FNE DG ++R+S +G+Y+I +G PRNP GRTG+VGRG L  WGPNHAADP++T WKR
Sbjct: 121 SPKFNEKDGHVERKSQNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKR 180

Query: 383 DENNEIIFDKVSQKPILKFVGIFRKHDNEWALPGGMVDPGELVTATIKREFSEEALNTLI 562
           DE+   I   VS K IL+FV I RK   EWA+PGGMVDPGE ++AT+KREF EEALN+L 
Sbjct: 181 DESGNKITHPVSGKCILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQ 240

Query: 563 KTTQEKKELYEKIDYLF-VNGTTIYTGYVDDPRNTDNAWIETVAVNFHDKDGDSLAQIKL 739
           K++ EK+E+ EK+  LF      IY GYVDDPRNTDNAW+ET AVN+HD+ G+++  + L
Sbjct: 241 KSSAEKREIEEKLHALFSQEHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGETMDNLTL 300

Query: 740 EAGDDAAAIRWIDLNKELKLYASHLSILSDLVDKHGAHW 856
           EAGDDA  ++W+D++ +LKLYASH   +  + +K  AHW
Sbjct: 301 EAGDDAGKVKWVDISDQLKLYASHSQFIKLVAEKRDAHW 339

>sp|Q5XIG0|NUDT9_RAT ADP-ribose pyrophosphatase, mitochondrial precursor (ADP-ribose
           diphosphatase) (Adenosine diphosphoribose
           pyrophosphatase) (ADPR-PPase) (ADP-ribose
           phosphohydrolase) (Nucleoside diphosphate-linked moiety
           X motif 9) (Nudix motif 9)
          Length = 350

 Score =  293 bits (750), Expect = 5e-79
 Identities = 142/279 (50%), Positives = 190/279 (68%), Gaps = 1/279 (0%)
 Frame = +2

Query: 23  HIRCREEFYpreKNIKRFHVSDEYVPWTVDFPEYEPTIYTSNKILTSNLTDDDILKNPFA 202
           H + R   YP  K ++R  V +E V W V++ +Y P  YT+  +L      D  +     
Sbjct: 62  HNKARTSPYPGSK-VERSKVPNEKVGWLVEWQDYNPVEYTAVSVLAGPQWADPQISESSF 120

Query: 203 DINFNELDGKIDRRSHHGMYDIVDGLPRNPYGRTGIVGRGCLYYWGPNHAADPVVTTWKR 382
              FNE DG ++R+S +G+Y+I +G PRNP GRTG+VGRG L  WGPNHAADP++T WKR
Sbjct: 121 SPRFNEKDGHVERKSQNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKR 180

Query: 383 DENNEIIFDKVSQKPILKFVGIFRKHDNEWALPGGMVDPGELVTATIKREFSEEALNTLI 562
           DE+   I   VS K IL+FV I RK   EWA+PGGMVDPGE ++AT+KREF EEALN+L 
Sbjct: 181 DESGNKITHPVSGKCILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQ 240

Query: 563 KTTQEKKELYEKIDYLF-VNGTTIYTGYVDDPRNTDNAWIETVAVNFHDKDGDSLAQIKL 739
           K++ EK+E+ EK+  LF      IY GYVDDPRNTDNAW+ET AVN+HD+ G+++  + L
Sbjct: 241 KSSAEKREIEEKLHALFSQEHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGETMDNLTL 300

Query: 740 EAGDDAAAIRWIDLNKELKLYASHLSILSDLVDKHGAHW 856
           EAGDDA  ++W+D++ +LKLYASH   +  + +K  AHW
Sbjct: 301 EAGDDAGKVKWVDISDQLKLYASHSQFIKLVAEKRDAHW 339

>sp|Q09297|NDX6_CAEEL Putative nudix hydrolase 6
          Length = 260

 Score =  208 bits (530), Expect = 2e-53
 Identities = 118/278 (42%), Positives = 165/278 (59%), Gaps = 3/278 (1%)
 Frame = +2

Query: 20  IHIRCRE-EFYpreKNIKRFHVSDEYVPWTVDFPEYEPTIYTSNKILTSNLTDDDILKNP 196
           +H +CR  +      NI R +V D  V W+ ++  Y P  +T  K+  +   D +I +  
Sbjct: 4   VHQKCRNIDTVYLGSNIHRLNVPDNLVKWSQEWSGYNPPAHTDPKVDGAVWADPEIDEKT 63

Query: 197 FADINFNELDGKIDRRSHHGMY--DIVDGLPRNPYGRTGIVGRGCLYYWGPNHAADPVVT 370
           F   ++N +DGKI+R S+   Y  D V   P NP GRTG+ GRG L  WGPNHAADP+V+
Sbjct: 64  FQP-SWNAIDGKINRVSYVCQYSFDPVTLRPLNPIGRTGLSGRGLLGRWGPNHAADPIVS 122

Query: 371 TWKRDENNEIIFDKVSQKPILKFVGIFRKHDNEWALPGGMVDPGELVTATIKREFSEEAL 550
             + ++N +           L+FV + R  + EWA+PGGMVD GE V+ T++REF+EEA+
Sbjct: 123 --RTNDNGD-----------LEFVAVQRHDNGEWAIPGGMVDAGEHVSQTLRREFAEEAM 169

Query: 551 NTLIKTTQEKKELYEKIDYLFVNGTTIYTGYVDDPRNTDNAWIETVAVNFHDKDGDSLAQ 730
           + ++ +        E +D L+ NG  +Y GYVDDPRNTDNAW+ETV  NFHD  G  L  
Sbjct: 170 HGIVDS--------ENLDELWNNGKELYRGYVDDPRNTDNAWMETVVFNFHDSKG-LLKN 220

Query: 731 IKLEAGDDAAAIRWIDLNKELKLYASHLSILSDLVDKH 844
           + L+AGDDA A+RWI +N    LYASH   +  L + H
Sbjct: 221 VALQAGDDAKALRWIAVNSNEPLYASHSHFIDLLKESH 258

>sp|Q91YD4|TRPM2_MOUSE Transient receptor potential cation channel subfamily M member 2
            (Long transient receptor potential channel 2) (LTrpC2)
            (LTrpC-2) (Transient receptor potential channel 7)
            (TrpC7)
          Length = 1507

 Score =  193 bits (491), Expect = 5e-49
 Identities = 109/291 (37%), Positives = 157/291 (53%), Gaps = 13/291 (4%)
 Frame = +2

Query: 23   HIRCREEFYpreKNIKRFHVSDEYVPWTVDFPEYEPTIYTSNK--ILTSNLTDDDILKNP 196
            H+  R   YP  + I RF V +E VPW  +F  Y+P  YT+ K   LT  + D      P
Sbjct: 1237 HVSARHLLYPNAR-IMRFPVPNEKVPWAAEFLIYDPPFYTAEKDVALTDPVGDT---AEP 1292

Query: 197  FADINFNELDGKIDRRSHHGMYDIVDGLPRNPYGRTGIVGRGCLYYWGPNHAADPVVTTW 376
             + I++N +DG  DRRS HG+Y +  G P NP GRTG+ GRG L ++GPNH   PVVT W
Sbjct: 1293 LSKISYNVVDGPTDRRSFHGVYVVEYGFPLNPMGRTGLRGRGSLSWFGPNHTLQPVVTRW 1352

Query: 377  KRDENNEIIFDKVSQKPILKFVGIFRKHDNEWALPGGMVDPGELVTATIKREFSEEALNT 556
            KR++   I   + S + +L+ + +       WALPGG  +PGE++   +KR         
Sbjct: 1353 KRNQGGAIC--RKSVRKMLEVLVMKLPRSEHWALPGGSREPGEMLPRKLKRVL------- 1403

Query: 557  LIKTTQEKKELYEKIDYLFVNGTTIYTGYVDDPRNTDNAWIETVAVNFHDKDGDSLAQIK 736
                   ++E +   + L + GT +Y GYVDDPRNTDNAWIETVAV+ H +D + +   +
Sbjct: 1404 -------RQEFWVAFETLLMQGTEVYKGYVDDPRNTDNAWIETVAVSIHFQDQNDMELKR 1456

Query: 737  LEAG-----------DDAAAIRWIDLNKELKLYASHLSILSDLVDKHGAHW 856
            LE             D   +  W  +++ + LYA+H +IL  +    GAH+
Sbjct: 1457 LEENLHTHDPKELTRDLKLSTEWQVVDRRIPLYANHKTILQKVASLFGAHF 1507

>sp|O94759|TRPM2_HUMAN Transient receptor potential cation channel subfamily M member 2
            (Long transient receptor potential channel 2) (LTrpC2)
            (LTrpC-2) (Transient receptor potential channel 7)
            (TrpC7) (Estrogen-responsive element associated gene
            protein 1)
          Length = 1503

 Score =  188 bits (477), Expect = 2e-47
 Identities = 105/282 (37%), Positives = 153/282 (54%), Gaps = 4/282 (1%)
 Frame = +2

Query: 23   HIRCREEFYpreKNIKRFHVSDEYVPWTVDFPEYEPTIYTSNKILTSNLTDDDILKNPFA 202
            H+  R   YP    + RF V +E VPW  +F  Y+P  YT+ +   + +        P +
Sbjct: 1239 HVNARHLLYPNCP-VTRFPVPNEKVPWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLS 1297

Query: 203  DINFNELDGKIDRRSHHGMYDIVDGLPRNPYGRTGIVGRGCLYYWGPNHAADPVVTTWKR 382
             I +N +DG  DRRS HG Y +  GLP NP GRTG+ GRG L  +GPNH   P+VT W+R
Sbjct: 1298 TIQYNVVDGLRDRRSFHGPYTVQAGLPLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRR 1357

Query: 383  DENNEIIFDKVSQKPILKFVGIFRKHDNEWALPGGMVDPGELVTATIKREFSEEALNTLI 562
            +E+  I   + S K +L+ + +       WALPGG  +PGE++   +KR           
Sbjct: 1358 NEDGAIC--RKSIKKMLEVLVVKLPLSEHWALPGGSREPGEMLPRKLKRIL--------- 1406

Query: 563  KTTQEKKELYEKIDYLFVNGTTIYTGYVDDPRNTDNAWIETVAVNFHDKDGDSL----AQ 730
                 ++E +   + L   G  +Y GY+DDPRNTDNAWIETVAV+ H +D + +      
Sbjct: 1407 -----RQEHWPSFENLLKCGMEVYKGYMDDPRNTDNAWIETVAVSVHFQDQNDVELNRLN 1461

Query: 731  IKLEAGDDAAAIRWIDLNKELKLYASHLSILSDLVDKHGAHW 856
              L A D  A+IRW  +++ + LYA+H ++L     + GAH+
Sbjct: 1462 SNLHACDSGASIRWQVVDRRIPLYANHKTLLQKAAAEFGAHY 1503

>sp|Q8N2Z3|NUD9P_HUMAN Hypothetical nucleoside diphosphate-linked moiety X motif 9P1
          Length = 120

 Score =  121 bits (303), Expect = 3e-27
 Identities = 62/123 (50%), Positives = 84/123 (68%), Gaps = 1/123 (0%)
 Frame = +2

Query: 488 MVDPGELVTATIKREFSEEALNTLIKTTQEKKELYEKIDYLFVNGT-TIYTGYVDDPRNT 664
           MVDPGE ++AT+KREF EEA+N+L K+ +E +EL  ++  L       +Y GYVDD RNT
Sbjct: 1   MVDPGEKISATLKREFGEEAMNSLQKSRKEMQELERQLHKLLSQEHFEVYKGYVDDSRNT 60

Query: 665 DNAWIETVAVNFHDKDGDSLAQIKLEAGDDAAAIRWIDLNKELKLYASHLSILSDLVDKH 844
           DN WIET AVN+ D+  D L    LEAGDDA  ++W+D+N +L+LYAS    +  + +K 
Sbjct: 61  DNCWIETEAVNYRDEIMDHL---PLEAGDDAKKVKWVDINDKLELYASLSQFIQLVAEKR 117

Query: 845 GAH 853
           GAH
Sbjct: 118 GAH 120

>sp|P34641|CED11_CAEEL Ced-11 protein
          Length = 1418

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 63/235 (26%), Positives = 93/235 (39%), Gaps = 21/235 (8%)
 Frame = +2

Query: 41   EFYpreKNIKRFHVSDEYVPWTVDFPEYEPTIYTSNKILTSNLTDDDILKNPFADINFNE 220
            E YP E NI +  V+    PWTV  P Y P  Y       +     D+ K  + DI   +
Sbjct: 1162 EKYP-ESNILKISVNMVSKPWTVLVPRYNPPFYCK----PAEDFPSDVQK--YVDIATEQ 1214

Query: 221  LDGKIDR----RSHHGMYDIVD--------GLPRNPYGRTGIVGRGCLYYWGPNHAADPV 364
              G++ R    R  + +    D        G P NP GRTG+ GRG    +G N     V
Sbjct: 1215 NVGELKRIWRSRQANDVTSSNDKCWKLSAAGFPLNPNGRTGMAGRGNHPRFGANRRCYYV 1274

Query: 365  VTTWKRDENNEIIFDKVSQKPILKFVGIFRKHDNEWALPGGMVDPGELVTATIK------ 526
            V +   +   +++ D  SQK I           NEW L     D  E +T+ +K      
Sbjct: 1275 VLSGGVEAKCQVLVD--SQKNI----------PNEWHLENSSKD--EHLTSILKMIGISD 1320

Query: 527  ---REFSEEALNTLIKTTQEKKELYEKIDYLFVNGTTIYTGYVDDPRNTDNAWIE 682
                 FS   L++ I T        ++I     +   + +   ++  +TDNAW E
Sbjct: 1321 SDAHMFSMRRLDSSIITAD------KRIPSNDTSPAHLASEVAENENDTDNAWTE 1369

>sp|Q58549|ADPP_METJA ADP-ribose pyrophosphatase (ADP-ribose diphosphatase) (Adenosine
           diphosphoribose pyrophosphatase) (ADPR-PPase)
           (ADP-ribose phosphohydrolase)
          Length = 169

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 48/167 (28%), Positives = 67/167 (40%), Gaps = 1/167 (0%)
 Frame = +2

Query: 332 YWGPNHAADPVVTTWKRDENNEIIFDKVSQKPILKFVGIFRKHDNEWALPGGMVDPGELV 511
           Y  P  A D ++     +++N+I+  K    P   F G F       ALPGG V+ GE V
Sbjct: 38  YLHPAVAVDGII-----EKDNKILLIKRKNNP---FKGCF-------ALPGGFVECGETV 82

Query: 512 TATIKREFSEEALNTLIKTTQEKKELYEKIDYLFVNGTTIYTGYVDDPRNTDNAWIETVA 691
              + RE  EE              L  K+  L      +Y+    DPR         ++
Sbjct: 83  EEAVVREIKEET------------GLIPKVKSLL----GVYSSPDRDPRG------HVIS 120

Query: 692 VNF-HDKDGDSLAQIKLEAGDDAAAIRWIDLNKELKLYASHLSILSD 829
           + F  D  G      +L+AGDDA    + DLN   KL   H  I+ D
Sbjct: 121 IVFILDVIGG-----ELKAGDDAKEAEFFDLNNLPKLAFDHEKIIKD 162

>sp|P35942|RRPO_ROTGI RNA-directed RNA polymerase subunit VP1 (Inner layer protein VP1)
           (Core protein VP1)
          Length = 1159

 Score = 38.1 bits (87), Expect = 0.035
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
 Frame = +2

Query: 542 EALNTLIKTTQEKKELYEKIDYLF-VNGTTIYTGYVDDPRNTDNAWIETVAVNFHDKDGD 718
           E L TL KT  E   L EKI+ L  +   T+Y G   D RN   +W+ T     + ++  
Sbjct: 56  ELLLTLKKTLDECSTLDEKIETLLRIRYFTVYVGDKSDKRNIIRSWLSTTINRLNVEEYA 115

Query: 719 SLAQIKLEA 745
           S+ +I+L+A
Sbjct: 116 SIQEIELQA 124

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,643,311
Number of Sequences: 369166
Number of extensions: 2104693
Number of successful extensions: 6595
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6286
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6572
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9510757740
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00822

  1. Dr_sW_021_A18
  2. Dr_sW_023_G16
  3. Dr_sW_007_J20