Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00817 (599 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9CWG1|GLIP1_MOUSE Glioma pathogenesis-related protein 1... 103 4e-22 sp|P16562|CRIS2_HUMAN Cysteine-rich secretory protein 2 pre... 103 4e-22 sp|Q16937|ASP_ANCCA Ancylostoma secreted protein precursor 102 6e-22 sp|Q60477|CRIS2_CAVPO Cysteine-rich secretory protein 2 pre... 101 1e-21 sp|O19010|CRIS3_HORSE Cysteine-rich secretory protein 3 pre... 100 3e-21 sp|P60623|CRVP_TRIST Cysteine-rich secretory protein precur... 97 4e-20 sp|P48060|GLIP1_HUMAN Glioma pathogenesis-related protein 1... 96 7e-20 sp|Q8JI40|CRVP_AGKHA Ablomin precursor 95 1e-19 sp|P35778|VA3_SOLIN Venom allergen 3 precursor (Venom aller... 94 2e-19 sp|P16563|CRIS2_MOUSE Cysteine-rich secretory protein 2 pre... 94 3e-19
>sp|Q9CWG1|GLIP1_MOUSE Glioma pathogenesis-related protein 1 precursor (GliPR 1) Length = 255 Score = 103 bits (256), Expect = 4e-22 Identities = 57/162 (35%), Positives = 79/162 (48%), Gaps = 5/162 (3%) Frame = +2 Query: 68 HNDYRRTIALGNGGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYA-DRQTSSFKMV 244 HN R ++ A NM +SWD L A+ + C H+ R +F + Sbjct: 41 HNQLRSKVS------PPARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQLHSRIHPNFTAL 94 Query: 245 GQNICLSP----DENVCQGLWYAEKDNYKFPTQQCSKVCGHYTQMVWASTYKMGCGKALC 412 G+NI L + WY E +Y F T++C VCGHYTQ+VWA +YK+GC LC Sbjct: 95 GENIWLGSLSIFSVSSAISAWYEEIKHYDFSTRKCRHVCGHYTQVVWADSYKLGCAVQLC 154 Query: 413 NGLISLVCNYGPAGNEQGADPYTEGFPAAECPPGTTKNNGLC 538 + +C+YGPAGN PY +G ++CP N LC Sbjct: 155 PNGANFICDYGPAGN-YPTWPYKQGATCSDCPKDDKCLNSLC 195
>sp|P16562|CRIS2_HUMAN Cysteine-rich secretory protein 2 precursor (CRISP-2) (Testis-specific protein TPX-1) Length = 243 Score = 103 bits (256), Expect = 4e-22 Identities = 63/177 (35%), Positives = 91/177 (51%), Gaps = 11/177 (6%) Frame = +2 Query: 44 LKNSLLKGHNDYRRTIALGNGGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQ 223 ++ ++ HN+ R+ ++ ASNM ++ W ++ AQR A KCT+ H DR+ Sbjct: 36 VQREIVNKHNELRKAVS------PPASNMLKMEWSREVTTNAQRWANKCTLQHSDPEDRK 89 Query: 224 TSSFKMVGQNICLSPDENVCQGL---WYAEKDNYKFPT--QQCSKVCGHYTQMVWASTYK 388 TS+ G+N+ +S D WY E ++ + + + V GHYTQ+VW STY+ Sbjct: 90 TST--RCGENLYMSSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQ 147 Query: 389 MGCGKALCNGLISL----VCNYGPAGNEQGA--DPYTEGFPAAECPPGTTKNNGLCS 541 +GCG A C SL VC Y PAGN PY +G P A CP K GLC+ Sbjct: 148 VGCGIAYCPNQDSLKYYYVCQYCPAGNNMNRKNTPYQQGTPCAGCPDDCDK--GLCT 202
>sp|Q16937|ASP_ANCCA Ancylostoma secreted protein precursor Length = 424 Score = 102 bits (255), Expect = 6e-22 Identities = 64/195 (32%), Positives = 89/195 (45%), Gaps = 25/195 (12%) Frame = +2 Query: 32 LDDTLKNSLLKGHNDYRRTIALG------NGGQTTASNMRELSWDADLEAKAQRHAEKCT 193 + D+++++ L HN++R ++A G G A+ M ++ +D ++EA A RH KC Sbjct: 233 MTDSVRDTFLSVHNEFRSSVARGLEPDALGGNAPKAAKMLKMVYDCEVEASAIRHGNKCV 292 Query: 194 INHDTYADRQTSSFKMVGQNI----CLSPDENVC----QGLWYAEKDNYKFPTQQCSKVC 349 H DR +G+NI L D+N LW+ E + Sbjct: 293 YQHSHGEDRPG-----LGENIYKTSVLKFDKNKAAKQASQLWWNELKEFGVGPSNVLTTA 347 Query: 350 ---------GHYTQMVWASTYKMGCGKALCNGLISLVCNYGPAGNEQGADPYTEGFPAAE 502 GHYTQM W +TYK+GC CN VC YGP GN G YT G P ++ Sbjct: 348 LWNRPGMQIGHYTQMAWDTTYKLGCAVVFCNDFTFGVCQYGPGGNYMGHVIYTMGQPCSQ 407 Query: 503 CPPGTT--KNNGLCS 541 C PG T GLCS Sbjct: 408 CSPGATCSVTEGLCS 422
Score = 47.4 bits (111), Expect = 3e-05 Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 20/187 (10%) Frame = +2 Query: 32 LDDTLKNSLLKGHNDYRRTIALG-----NGGQTTASNMRELSWDADLEAKAQRHAEKCTI 196 + D + + L HN+ RR +A G +G A NM +LSWD +E + Q + C Sbjct: 32 ITDKDRQAFLDFHNNARRRVAKGVEDSNSGKLNPAKNMYKLSWDCAMEQQLQDAIQSCP- 90 Query: 197 NHDTYADRQTSSFKMVGQNICL------SPD-----ENVCQGLWYAEKDNYKFPTQQCSK 343 + + V QN+ PD E G W K N P + + Sbjct: 91 -------SAFAGIQGVAQNVMSWSSSGGFPDPSVKIEQTLSGWWSGAKKNGVGPDNKYNG 143 Query: 344 V-CGHYTQMVWASTYKMGCGKALCNGLISLVCNYGPAGNEQGADPYTEG---FPAAECPP 511 ++ MV++ T K+GC +C +++ C Y G + G A+C Sbjct: 144 GGLFAFSNMVYSETTKLGCAYKVCGTKLAVSCIYNGVGYITNQPMWETGQACKTGADC-- 201 Query: 512 GTTKNNG 532 T KN+G Sbjct: 202 STYKNSG 208
>sp|Q60477|CRIS2_CAVPO Cysteine-rich secretory protein 2 precursor (CRISP-2) (Testis-specific protein TPX-1) (Autoantigen 1) (25 kDa acrosomal autoantigen) (AA1) Length = 244 Score = 101 bits (252), Expect = 1e-21 Identities = 62/187 (33%), Positives = 92/187 (49%), Gaps = 11/187 (5%) Frame = +2 Query: 14 FLQVFCLDDTLKNSLLKGHNDYRRTIALGNGGQTTASNMRELSWDADLEAKAQRHAEKCT 193 F + ++N ++ HN R+++ ASNM ++ W + AQ+ A +CT Sbjct: 27 FTALITTQSQVQNEIINKHNQLRKSVT------PPASNMLKMEWSREAAVNAQKWANRCT 80 Query: 194 INHDTYADRQTSSFKMVGQNICLSPDENVCQGL---WYAEKDNYKFPT--QQCSKVCGHY 358 + H DR+TS+ G+N+ +S D + W+ E ++ F + + V GHY Sbjct: 81 LVHSNPDDRKTST--KCGENLYMSSDPSSWSDAIQSWFDESQDFTFGVGPKSHNAVVGHY 138 Query: 359 TQMVWASTYKMGCGKALCNGLISL----VCNYGPAGNE--QGADPYTEGFPAAECPPGTT 520 TQ+VW S+Y +GCG A C SL VC Y PAGN PY +G P A CP Sbjct: 139 TQLVWYSSYLVGCGIAYCPNQDSLKYYYVCQYCPAGNNVYTKNTPYKQGIPCASCPGHC- 197 Query: 521 KNNGLCS 541 NGLC+ Sbjct: 198 -ENGLCT 203
>sp|O19010|CRIS3_HORSE Cysteine-rich secretory protein 3 precursor (CRISP-3) Length = 245 Score = 100 bits (249), Expect = 3e-21 Identities = 62/177 (35%), Positives = 91/177 (51%), Gaps = 11/177 (6%) Frame = +2 Query: 44 LKNSLLKGHNDYRRTIALGNGGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQ 223 ++ ++ HND RRT++ ASNM ++ WD+ AQ A KC + H DR Sbjct: 37 VQKEIVNKHNDLRRTVS------PLASNMLKMQWDSKTATNAQNWANKCLLQHSKAEDRA 90 Query: 224 TSSFKMVGQNICLSPDENVCQGL---WYAEKDNYKFPT--QQCSKVCGHYTQMVWASTYK 388 + K G+N+ +S N W+ E ++K+ + + V GHYTQ+VW S+Y+ Sbjct: 91 VGTMKC-GENLFMSSIPNSWSDAIQNWHDEVHDFKYGVGPKTPNAVVGHYTQVVWYSSYR 149 Query: 389 MGCGKALC--NGLIS--LVCNYGPAGN--EQGADPYTEGFPAAECPPGTTKNNGLCS 541 +GCG A C G + VC Y PAGN + PY +G P A CP +NGLC+ Sbjct: 150 VGCGIAYCPKQGTLKYYYVCQYCPAGNYVNKINTPYEQGTPCARCPGNC--DNGLCT 204
>sp|P60623|CRVP_TRIST Cysteine-rich secretory protein precursor (Stecrisp) Length = 233 Score = 96.7 bits (239), Expect = 4e-20 Identities = 61/176 (34%), Positives = 86/176 (48%), Gaps = 10/176 (5%) Frame = +2 Query: 44 LKNSLLKGHNDYRRTIALGNGGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQ 223 ++N ++ HN RR++ TASNM + W + A+R A +C +H +Y R Sbjct: 26 IQNEIVDLHNSLRRSV------NPTASNMLRMEWYPEAADNAERWAYRCIESHSSYESRV 79 Query: 224 TSSFKMVGQNICLSPDENVCQGLWYAEKDNYK-----FPTQQCSKVCGHYTQMVWASTYK 388 K G+NI +SP + +A D YK + V GHYTQ+VW +Y+ Sbjct: 80 IEGIKC-GENIYMSPYPMKWTDIIHAWHDEYKDFKYGVGADPPNAVTGHYTQIVWYKSYR 138 Query: 389 MGCGKALCNG---LISLVCNYGPAGNEQG--ADPYTEGFPAAECPPGTTKNNGLCS 541 +GC A C VC Y PAGN G A PYT G P +CP + +NGLC+ Sbjct: 139 IGCAAAYCPSSPYSYFFVCQYCPAGNFIGKTATPYTSGTPCGDCP--SDCDNGLCT 192
>sp|P48060|GLIP1_HUMAN Glioma pathogenesis-related protein 1 precursor (GliPR 1) (RTVP-1 protein) Length = 266 Score = 95.9 bits (237), Expect = 7e-20 Identities = 60/173 (34%), Positives = 85/173 (49%), Gaps = 16/173 (9%) Frame = +2 Query: 68 HNDYRRTIALGNGGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYAD---RQTSSFK 238 HN +R + + TAS+M ++WD L A+ A C +H+T + +F Sbjct: 41 HNKFRSEV------KPTASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFT 94 Query: 239 MVGQNICLS--PDENVCQGL--WYAEKDNYKFPTQQCSKVCGHYTQMVWASTYKMGCGKA 406 +G+NI P +V + WY E +Y F T+ C KVCGHYTQ+VWA +YK+GC Sbjct: 95 SLGENIWTGSVPIFSVSSAITNWYDEIQDYDFKTRICKKVCGHYTQVVWADSYKVGCAVQ 154 Query: 407 LC---NGLISL------VCNYGPAGNEQGADPYTEGFPAAECPPGTTKNNGLC 538 C +G +L +CNYGP GN PY G + CP + LC Sbjct: 155 FCPKVSGFDALSNGAHFICNYGPGGN-YPTWPYKRGATCSACPNNDKCLDNLC 206
>sp|Q8JI40|CRVP_AGKHA Ablomin precursor Length = 240 Score = 95.1 bits (235), Expect = 1e-19 Identities = 60/176 (34%), Positives = 89/176 (50%), Gaps = 10/176 (5%) Frame = +2 Query: 44 LKNSLLKGHNDYRRTIALGNGGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQ 223 ++N ++ HN RR++ TASNM ++ W + A A+R A +C +H + R Sbjct: 33 IQNEIVDLHNSLRRSV------NPTASNMLKMEWYPEAAANAERWAYRCIEDHSSPDSRV 86 Query: 224 TSSFKMVGQNICLSPDENVCQGL---WYAEKDNYKFP--TQQCSKVCGHYTQMVWASTYK 388 K G+NI +SP + W+ E N+K+ + V GH+TQ+VW +Y+ Sbjct: 87 LEGIKC-GENIYMSPIPMKWTDIIHIWHDEYKNFKYGIGADPPNAVSGHFTQIVWYKSYR 145 Query: 389 MGCGKALCNG---LISLVCNYGPAGNEQG--ADPYTEGFPAAECPPGTTKNNGLCS 541 GC A C VC Y PAGN +G A PYT G P +CP + +NGLC+ Sbjct: 146 AGCAAAYCPSSEYSYFYVCQYCPAGNMRGKTATPYTSGPPCGDCP--SACDNGLCT 199
>sp|P35778|VA3_SOLIN Venom allergen 3 precursor (Venom allergen III) (Allergen Sol i 3) (Sol i III) Length = 234 Score = 94.4 bits (233), Expect = 2e-19 Identities = 68/175 (38%), Positives = 89/175 (50%), Gaps = 28/175 (16%) Frame = +2 Query: 38 DTLKNSLLKGHNDYRRTIALG------NGGQTTASNMRELSWDADLEAKAQRHAEKCTIN 199 D K++++ HN+ R+ +A G NG Q A M L+WD +L AQR A +CT Sbjct: 62 DAEKDAIVNKHNELRQRVASGKEMRGTNGPQPPAVKMPNLTWDPELATIAQRWANQCTFE 121 Query: 200 HDTYADRQTSSFKMVGQNICL---------SPDENVCQGLWYAEKDNY------KFPTQQ 334 HD A R F VGQNI +P+E + LWY E ++ FP+ Sbjct: 122 HD--ACRNVERF-AVGQNIAATSSSGKNKSTPNEMIL--LWYNEVKDFDNRWISSFPSDD 176 Query: 335 --CSKVCGHYTQMVWASTYKMGCGKALCNGLIS-----LVCNYGPAGNEQGADPY 478 KV GHYTQ+VWA T K+GCG+ + + LVCNYGPAGN GA Y Sbjct: 177 NILMKV-GHYTQIVWAKTTKIGCGRIMFKEPDNWTKHYLVCNYGPAGNVLGAPIY 230
>sp|P16563|CRIS2_MOUSE Cysteine-rich secretory protein 2 precursor (CRISP-2) (Testis-specific protein TPX-1) Length = 243 Score = 94.0 bits (232), Expect = 3e-19 Identities = 54/176 (30%), Positives = 91/176 (51%), Gaps = 10/176 (5%) Frame = +2 Query: 44 LKNSLLKGHNDYRRTIALGNGGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQ 223 ++ ++ HN+ RR++ T S++ ++ W AQ+ A KC + H + DR+ Sbjct: 37 VQREIVNKHNELRRSV------NPTGSDILKMEWSIQATTNAQKWANKCILEHSSKDDRK 90 Query: 224 TSSFKMVGQNICLSPDENVCQGL---WYAEKDNYKFPT-QQCSKVCGHYTQMVWASTYKM 391 + G+N+ +S D + + WY E +++ + + + GHYTQ+VW S++K+ Sbjct: 91 INI--RCGENLYMSTDPTLWSTVIQSWYNENEDFVYGVGAKPNSAVGHYTQLVWYSSFKI 148 Query: 392 GCGKALCNGLISL----VCNYGPAGNE--QGADPYTEGFPAAECPPGTTKNNGLCS 541 GCG A C +L VC+Y P GN + + PY +G P A CP NGLC+ Sbjct: 149 GCGIAYCPNQDNLKYFYVCHYCPMGNNVMKKSTPYQQGTPCASCP--NNCENGLCT 202
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 76,354,196 Number of Sequences: 369166 Number of extensions: 1737394 Number of successful extensions: 4925 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4548 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4792 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4602033670 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)