Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_O16
(496 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CWG1|GLIP1_MOUSE Glioma pathogenesis-related protein 1... 102 4e-22
sp|P16562|CRIS2_HUMAN Cysteine-rich secretory protein 2 pre... 99 4e-21
sp|Q60477|CRIS2_CAVPO Cysteine-rich secretory protein 2 pre... 95 8e-20
sp|P48060|GLIP1_HUMAN Glioma pathogenesis-related protein 1... 94 2e-19
sp|O19010|CRIS3_HORSE Cysteine-rich secretory protein 3 pre... 92 7e-19
sp|P60623|CRVP_TRIST Cysteine-rich secretory protein precur... 91 2e-18
sp|Q16937|ASP_ANCCA Ancylostoma secreted protein precursor 91 2e-18
sp|Q8JI40|CRVP_AGKHA Ablomin precursor 89 6e-18
sp|P16563|CRIS2_MOUSE Cysteine-rich secretory protein 2 pre... 89 7e-18
sp|Q8JI38|CRVP_LATSE Latisemin precursor 88 1e-17
>sp|Q9CWG1|GLIP1_MOUSE Glioma pathogenesis-related protein 1 precursor (GliPR 1)
Length = 255
Score = 102 bits (255), Expect = 4e-22
Identities = 54/145 (37%), Positives = 74/145 (51%), Gaps = 5/145 (3%)
Frame = +1
Query: 16 ASNMRELSWDADLEAKAQRHAEKCTINHDTYA-DRQTSSFKMVGQNICLSP----DENVC 180
A NM +SWD L A+ + C H+ R +F +G+NI L +
Sbjct: 52 ARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQLHSRIHPNFTALGENIWLGSLSIFSVSSA 111
Query: 181 QGLWYAEKDNYKFPTQQCSKVCGHYTQMVWASTYKMGCGKALCNGLISLVCNYGPAGNEQ 360
WY E +Y F T++C VCGHYTQ+VWA +YK+GC LC + +C+YGPAGN
Sbjct: 112 ISAWYEEIKHYDFSTRKCRHVCGHYTQVVWADSYKLGCAVQLCPNGANFICDYGPAGN-Y 170
Query: 361 GADPYTEGFPAAECPPGTTKNNGLC 435
PY +G ++CP N LC
Sbjct: 171 PTWPYKQGATCSDCPKDDKCLNSLC 195
>sp|P16562|CRIS2_HUMAN Cysteine-rich secretory protein 2 precursor (CRISP-2)
(Testis-specific protein TPX-1)
Length = 243
Score = 99.4 bits (246), Expect = 4e-21
Identities = 60/152 (39%), Positives = 80/152 (52%), Gaps = 11/152 (7%)
Frame = +1
Query: 16 ASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNICLSPDENVCQGL-- 189
ASNM ++ W ++ AQR A KCT+ H DR+TS+ G+N+ +S D
Sbjct: 55 ASNMLKMEWSREVTTNAQRWANKCTLQHSDPEDRKTST--RCGENLYMSSDPTSWSSAIQ 112
Query: 190 -WYAEKDNYKFPT--QQCSKVCGHYTQMVWASTYKMGCGKALCNGLISL----VCNYGPA 348
WY E ++ + + + V GHYTQ+VW STY++GCG A C SL VC Y PA
Sbjct: 113 SWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPNQDSLKYYYVCQYCPA 172
Query: 349 GNEQGA--DPYTEGFPAAECPPGTTKNNGLCS 438
GN PY +G P A CP K GLC+
Sbjct: 173 GNNMNRKNTPYQQGTPCAGCPDDCDK--GLCT 202
>sp|Q60477|CRIS2_CAVPO Cysteine-rich secretory protein 2 precursor (CRISP-2)
(Testis-specific protein TPX-1) (Autoantigen 1) (25 kDa
acrosomal autoantigen) (AA1)
Length = 244
Score = 95.1 bits (235), Expect = 8e-20
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 11/152 (7%)
Frame = +1
Query: 16 ASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNICLSPDENVCQGL-- 189
ASNM ++ W + AQ+ A +CT+ H DR+TS+ G+N+ +S D +
Sbjct: 56 ASNMLKMEWSREAAVNAQKWANRCTLVHSNPDDRKTST--KCGENLYMSSDPSSWSDAIQ 113
Query: 190 -WYAEKDNYKFPT--QQCSKVCGHYTQMVWASTYKMGCGKALCNGLISL----VCNYGPA 348
W+ E ++ F + + V GHYTQ+VW S+Y +GCG A C SL VC Y PA
Sbjct: 114 SWFDESQDFTFGVGPKSHNAVVGHYTQLVWYSSYLVGCGIAYCPNQDSLKYYYVCQYCPA 173
Query: 349 GNE--QGADPYTEGFPAAECPPGTTKNNGLCS 438
GN PY +G P A CP NGLC+
Sbjct: 174 GNNVYTKNTPYKQGIPCASCPGHC--ENGLCT 203
>sp|P48060|GLIP1_HUMAN Glioma pathogenesis-related protein 1 precursor (GliPR 1) (RTVP-1
protein)
Length = 266
Score = 94.0 bits (232), Expect = 2e-19
Identities = 57/157 (36%), Positives = 79/157 (50%), Gaps = 16/157 (10%)
Frame = +1
Query: 13 TASNMRELSWDADLEAKAQRHAEKCTINHDTYAD---RQTSSFKMVGQNICLS--PDENV 177
TAS+M ++WD L A+ A C +H+T + +F +G+NI P +V
Sbjct: 51 TASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGENIWTGSVPIFSV 110
Query: 178 CQGL--WYAEKDNYKFPTQQCSKVCGHYTQMVWASTYKMGCGKALC---NGLISL----- 327
+ WY E +Y F T+ C KVCGHYTQ+VWA +YK+GC C +G +L
Sbjct: 111 SSAITNWYDEIQDYDFKTRICKKVCGHYTQVVWADSYKVGCAVQFCPKVSGFDALSNGAH 170
Query: 328 -VCNYGPAGNEQGADPYTEGFPAAECPPGTTKNNGLC 435
+CNYGP GN PY G + CP + LC
Sbjct: 171 FICNYGPGGN-YPTWPYKRGATCSACPNNDKCLDNLC 206
>sp|O19010|CRIS3_HORSE Cysteine-rich secretory protein 3 precursor (CRISP-3)
Length = 245
Score = 92.0 bits (227), Expect = 7e-19
Identities = 56/152 (36%), Positives = 79/152 (51%), Gaps = 11/152 (7%)
Frame = +1
Query: 16 ASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNICLSPDENVCQGL-- 189
ASNM ++ WD+ AQ A KC + H DR + K G+N+ +S N
Sbjct: 56 ASNMLKMQWDSKTATNAQNWANKCLLQHSKAEDRAVGTMKC-GENLFMSSIPNSWSDAIQ 114
Query: 190 -WYAEKDNYKFPT--QQCSKVCGHYTQMVWASTYKMGCGKALC--NGLIS--LVCNYGPA 348
W+ E ++K+ + + V GHYTQ+VW S+Y++GCG A C G + VC Y PA
Sbjct: 115 NWHDEVHDFKYGVGPKTPNAVVGHYTQVVWYSSYRVGCGIAYCPKQGTLKYYYVCQYCPA 174
Query: 349 GN--EQGADPYTEGFPAAECPPGTTKNNGLCS 438
GN + PY +G P A CP +NGLC+
Sbjct: 175 GNYVNKINTPYEQGTPCARCPGNC--DNGLCT 204
>sp|P60623|CRVP_TRIST Cysteine-rich secretory protein precursor (Stecrisp)
Length = 233
Score = 90.5 bits (223), Expect = 2e-18
Identities = 56/152 (36%), Positives = 75/152 (49%), Gaps = 10/152 (6%)
Frame = +1
Query: 13 TASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNICLSPDENVCQGLW 192
TASNM + W + A+R A +C +H +Y R K G+NI +SP +
Sbjct: 44 TASNMLRMEWYPEAADNAERWAYRCIESHSSYESRVIEGIKC-GENIYMSPYPMKWTDII 102
Query: 193 YAEKDNYK-----FPTQQCSKVCGHYTQMVWASTYKMGCGKALCNG---LISLVCNYGPA 348
+A D YK + V GHYTQ+VW +Y++GC A C VC Y PA
Sbjct: 103 HAWHDEYKDFKYGVGADPPNAVTGHYTQIVWYKSYRIGCAAAYCPSSPYSYFFVCQYCPA 162
Query: 349 GNEQG--ADPYTEGFPAAECPPGTTKNNGLCS 438
GN G A PYT G P +CP + +NGLC+
Sbjct: 163 GNFIGKTATPYTSGTPCGDCP--SDCDNGLCT 192
>sp|Q16937|ASP_ANCCA Ancylostoma secreted protein precursor
Length = 424
Score = 90.5 bits (223), Expect = 2e-18
Identities = 57/165 (34%), Positives = 72/165 (43%), Gaps = 19/165 (11%)
Frame = +1
Query: 1 GGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNI----CLSPD 168
G A+ M ++ +D ++EA A RH KC H DR +G+NI L D
Sbjct: 263 GNAPKAAKMLKMVYDCEVEASAIRHGNKCVYQHSHGEDRPG-----LGENIYKTSVLKFD 317
Query: 169 ENVC----QGLWYAEKDNYKFPTQQCSKVC---------GHYTQMVWASTYKMGCGKALC 309
+N LW+ E + GHYTQM W +TYK+GC C
Sbjct: 318 KNKAAKQASQLWWNELKEFGVGPSNVLTTALWNRPGMQIGHYTQMAWDTTYKLGCAVVFC 377
Query: 310 NGLISLVCNYGPAGNEQGADPYTEGFPAAECPPGTT--KNNGLCS 438
N VC YGP GN G YT G P ++C PG T GLCS
Sbjct: 378 NDFTFGVCQYGPGGNYMGHVIYTMGQPCSQCSPGATCSVTEGLCS 422
Score = 38.5 bits (88), Expect = 0.009
Identities = 39/158 (24%), Positives = 60/158 (37%), Gaps = 15/158 (9%)
Frame = +1
Query: 1 GGQTTASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNICL------S 162
G A NM +LSWD +E + Q + C + + V QN+
Sbjct: 61 GKLNPAKNMYKLSWDCAMEQQLQDAIQSCP--------SAFAGIQGVAQNVMSWSSSGGF 112
Query: 163 PD-----ENVCQGLWYAEKDNYKFPTQQCSKV-CGHYTQMVWASTYKMGCGKALCNGLIS 324
PD E G W K N P + + ++ MV++ T K+GC +C ++
Sbjct: 113 PDPSVKIEQTLSGWWSGAKKNGVGPDNKYNGGGLFAFSNMVYSETTKLGCAYKVCGTKLA 172
Query: 325 LVCNYGPAGNEQGADPYTEG---FPAAECPPGTTKNNG 429
+ C Y G + G A+C T KN+G
Sbjct: 173 VSCIYNGVGYITNQPMWETGQACKTGADC--STYKNSG 208
>sp|Q8JI40|CRVP_AGKHA Ablomin precursor
Length = 240
Score = 89.0 bits (219), Expect = 6e-18
Identities = 55/152 (36%), Positives = 78/152 (51%), Gaps = 10/152 (6%)
Frame = +1
Query: 13 TASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNICLSPDENVCQGL- 189
TASNM ++ W + A A+R A +C +H + R K G+NI +SP +
Sbjct: 51 TASNMLKMEWYPEAAANAERWAYRCIEDHSSPDSRVLEGIKC-GENIYMSPIPMKWTDII 109
Query: 190 --WYAEKDNYKFP--TQQCSKVCGHYTQMVWASTYKMGCGKALCNG---LISLVCNYGPA 348
W+ E N+K+ + V GH+TQ+VW +Y+ GC A C VC Y PA
Sbjct: 110 HIWHDEYKNFKYGIGADPPNAVSGHFTQIVWYKSYRAGCAAAYCPSSEYSYFYVCQYCPA 169
Query: 349 GNEQG--ADPYTEGFPAAECPPGTTKNNGLCS 438
GN +G A PYT G P +CP + +NGLC+
Sbjct: 170 GNMRGKTATPYTSGPPCGDCP--SACDNGLCT 199
>sp|P16563|CRIS2_MOUSE Cysteine-rich secretory protein 2 precursor (CRISP-2)
(Testis-specific protein TPX-1)
Length = 243
Score = 88.6 bits (218), Expect = 7e-18
Identities = 50/152 (32%), Positives = 80/152 (52%), Gaps = 10/152 (6%)
Frame = +1
Query: 13 TASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNICLSPDENVCQGL- 189
T S++ ++ W AQ+ A KC + H + DR+ + G+N+ +S D + +
Sbjct: 55 TGSDILKMEWSIQATTNAQKWANKCILEHSSKDDRKINI--RCGENLYMSTDPTLWSTVI 112
Query: 190 --WYAEKDNYKFPT-QQCSKVCGHYTQMVWASTYKMGCGKALCNGLISL----VCNYGPA 348
WY E +++ + + + GHYTQ+VW S++K+GCG A C +L VC+Y P
Sbjct: 113 QSWYNENEDFVYGVGAKPNSAVGHYTQLVWYSSFKIGCGIAYCPNQDNLKYFYVCHYCPM 172
Query: 349 GNE--QGADPYTEGFPAAECPPGTTKNNGLCS 438
GN + + PY +G P A CP NGLC+
Sbjct: 173 GNNVMKKSTPYQQGTPCASCP--NNCENGLCT 202
>sp|Q8JI38|CRVP_LATSE Latisemin precursor
Length = 238
Score = 87.8 bits (216), Expect = 1e-17
Identities = 56/151 (37%), Positives = 73/151 (48%), Gaps = 9/151 (5%)
Frame = +1
Query: 13 TASNMRELSWDADLEAKAQRHAEKCTINHDTYADRQTSSFKMVGQNICLSPD----ENVC 180
TA NM ++ W++D AQR A++C+ H R F G+N+ +S V
Sbjct: 51 TARNMLQMEWNSDAAQNAQRWADRCSFAHSPSHLRTVGKFSC-GENLFMSSQPYAWSRVI 109
Query: 181 QGLWYAEKDN--YKFPTQQCSKVCGHYTQMVWASTYKMGCGKALCNGLISL-VCNYGPAG 351
Q WY E N Y V GHYTQ+VW ++ +GC A C+ L VC Y PAG
Sbjct: 110 QS-WYDENKNFIYDVGANPPGSVIGHYTQIVWYKSHLLGCAAARCSSSKYLYVCQYCPAG 168
Query: 352 NEQG--ADPYTEGFPAAECPPGTTKNNGLCS 438
N G A PY G P +CP NGLC+
Sbjct: 169 NIIGSIATPYKSGPPCGDCPSACV--NGLCT 197
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,825,284
Number of Sequences: 369166
Number of extensions: 1547322
Number of successful extensions: 4386
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4047
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4263
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3069744620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)