Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00785 (647 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q68FG0|HC127_MOUSE Hepatocellular carcinoma-associated a... 69 1e-11 sp|Q59268|MGM_EUBBA 2-methyleneglutarate mutase (Alpha-meth... 32 1.1 sp|Q92833|JARD2_HUMAN Jumonji protein (Jumonji/ARID domain-... 30 4.1 sp|P07476|INVO_HUMAN Involucrin 30 5.4 sp|Q8NVZ9|METK_STAAW S-adenosylmethionine synthetase (Methi... 30 5.4 sp|Q6GFR6|METK_STAAR S-adenosylmethionine synthetase (Methi... 30 5.4 sp|P66767|METK_STAAN S-adenosylmethionine synthetase (Methi... 30 5.4 sp|Q9Y618|NCOR2_HUMAN Nuclear receptor corepressor 2 (N-CoR... 30 5.4 sp|P14708|INVO_PONPY Involucrin 30 5.4 sp|P14591|INVO_PANPA Involucrin 30 5.4
>sp|Q68FG0|HC127_MOUSE Hepatocellular carcinoma-associated antigen 127 homolog sp|Q9NQZ6|HC127_HUMAN Hepatocellular carcinoma-associated antigen 127 Length = 224 Score = 68.6 bits (166), Expect = 1e-11 Identities = 30/39 (76%), Positives = 31/39 (79%) Frame = +2 Query: 335 TEGLHQQPPPMKKCQSCQEQIHRNAPICPLCKAKSRSIN 451 T QQPPPMK C SC +QIHRNAPICPLCKAKSRS N Sbjct: 176 TATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRN 214
>sp|Q59268|MGM_EUBBA 2-methyleneglutarate mutase (Alpha-methyleneglutarate mutase) Length = 614 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/54 (27%), Positives = 27/54 (50%) Frame = +2 Query: 74 YMNPESNVIRPGQVFTRPDITGLGGSMNSFDPTALLNINNPSNDNLGQINASTE 235 + NP N++ F+R +T G + + P A ++ P+ D++GQ TE Sbjct: 290 FQNPPGNLVAEAAHFSRMAVTAKLGGADFYRPKAAESVGIPTGDSMGQAIWGTE 343
>sp|Q92833|JARD2_HUMAN Jumonji protein (Jumonji/ARID domain-containing protein 2) Length = 1246 Score = 30.4 bits (67), Expect = 4.1 Identities = 14/60 (23%), Positives = 25/60 (41%) Frame = +2 Query: 224 ASTESHVHKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHR 403 A+ H D + EQ++ H P+T + G H PP + Q ++Q+ + Sbjct: 246 ATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSK 305
>sp|P07476|INVO_HUMAN Involucrin Length = 585 Score = 30.0 bits (66), Expect = 5.4 Identities = 16/43 (37%), Positives = 24/43 (55%) Frame = +2 Query: 302 TMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLCK 430 T+P TL+ L E L PPP+ + QEQ+ + P+ P C+ Sbjct: 6 TLPVTLSPALSQELLKTVPPPV---NTHQEQMKQPTPLPPPCQ 45
>sp|Q8NVZ9|METK_STAAW S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT) sp|Q6G8E3|METK_STAAS S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT) sp|Q5HEY9|METK_STAAC S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT) Length = 397 Score = 30.0 bits (66), Expect = 5.4 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Frame = +2 Query: 170 TALLNINNPSNDNLGQINASTESHV-HKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGL 346 T +++ + + L QI ++HV + PE + NEQ+ F PT + G G GL Sbjct: 196 TIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGL 255
>sp|Q6GFR6|METK_STAAR S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT) Length = 397 Score = 30.0 bits (66), Expect = 5.4 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Frame = +2 Query: 170 TALLNINNPSNDNLGQINASTESHV-HKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGL 346 T +++ + + L QI ++HV + PE + NEQ+ F PT + G G GL Sbjct: 196 TIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGL 255
>sp|P66767|METK_STAAN S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT) sp|P66766|METK_STAAM S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT) Length = 398 Score = 30.0 bits (66), Expect = 5.4 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Frame = +2 Query: 170 TALLNINNPSNDNLGQINASTESHV-HKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGL 346 T +++ + + L QI ++HV + PE + NEQ+ F PT + G G GL Sbjct: 196 TIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGL 255
>sp|Q9Y618|NCOR2_HUMAN Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor-associating factor) (TRAC) (CTG repeat protein 26) (SMAP270) Length = 2517 Score = 30.0 bits (66), Expect = 5.4 Identities = 14/35 (40%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Frame = +2 Query: 44 DINELYMLHHYMNPESNVIRPG-QVFTRPDITGLG 145 +IN+ H+ PE N+ +PG ++F P ITG G Sbjct: 2289 EINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTG 2323
>sp|P14708|INVO_PONPY Involucrin Length = 835 Score = 30.0 bits (66), Expect = 5.4 Identities = 16/43 (37%), Positives = 24/43 (55%) Frame = +2 Query: 302 TMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLCK 430 T+P TL+ L E L PPP+ + QEQ+ + P+ P C+ Sbjct: 6 TLPVTLSPALSQELLKTVPPPV---NTQQEQMKQPTPLPPPCQ 45
>sp|P14591|INVO_PANPA Involucrin Length = 560 Score = 30.0 bits (66), Expect = 5.4 Identities = 16/43 (37%), Positives = 24/43 (55%) Frame = +2 Query: 302 TMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLCK 430 T+P TL+ L E L PPP+ + QEQ+ + P+ P C+ Sbjct: 6 TLPVTLSPALSQELLKTVPPPV---NTQQEQMKQPTPLPPPCQ 45
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,913,319 Number of Sequences: 369166 Number of extensions: 1164473 Number of successful extensions: 3544 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3455 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3543 length of database: 68,354,980 effective HSP length: 106 effective length of database: 48,773,070 effective search space used: 5316264630 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)