Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_E17
(647 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q68FG0|HC127_MOUSE Hepatocellular carcinoma-associated a... 69 1e-11
sp|Q59268|MGM_EUBBA 2-methyleneglutarate mutase (Alpha-meth... 32 1.1
sp|Q92833|JARD2_HUMAN Jumonji protein (Jumonji/ARID domain-... 30 4.1
sp|P07476|INVO_HUMAN Involucrin 30 5.4
sp|Q8NVZ9|METK_STAAW S-adenosylmethionine synthetase (Methi... 30 5.4
sp|Q6GFR6|METK_STAAR S-adenosylmethionine synthetase (Methi... 30 5.4
sp|P66767|METK_STAAN S-adenosylmethionine synthetase (Methi... 30 5.4
sp|Q9Y618|NCOR2_HUMAN Nuclear receptor corepressor 2 (N-CoR... 30 5.4
sp|P14708|INVO_PONPY Involucrin 30 5.4
sp|P14591|INVO_PANPA Involucrin 30 5.4
>sp|Q68FG0|HC127_MOUSE Hepatocellular carcinoma-associated antigen 127 homolog
sp|Q9NQZ6|HC127_HUMAN Hepatocellular carcinoma-associated antigen 127
Length = 224
Score = 68.6 bits (166), Expect = 1e-11
Identities = 30/39 (76%), Positives = 31/39 (79%)
Frame = +2
Query: 335 TEGLHQQPPPMKKCQSCQEQIHRNAPICPLCKAKSRSIN 451
T QQPPPMK C SC +QIHRNAPICPLCKAKSRS N
Sbjct: 176 TATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRN 214
>sp|Q59268|MGM_EUBBA 2-methyleneglutarate mutase (Alpha-methyleneglutarate mutase)
Length = 614
Score = 32.3 bits (72), Expect = 1.1
Identities = 15/54 (27%), Positives = 27/54 (50%)
Frame = +2
Query: 74 YMNPESNVIRPGQVFTRPDITGLGGSMNSFDPTALLNINNPSNDNLGQINASTE 235
+ NP N++ F+R +T G + + P A ++ P+ D++GQ TE
Sbjct: 290 FQNPPGNLVAEAAHFSRMAVTAKLGGADFYRPKAAESVGIPTGDSMGQAIWGTE 343
>sp|Q92833|JARD2_HUMAN Jumonji protein (Jumonji/ARID domain-containing protein 2)
Length = 1246
Score = 30.4 bits (67), Expect = 4.1
Identities = 14/60 (23%), Positives = 25/60 (41%)
Frame = +2
Query: 224 ASTESHVHKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHR 403
A+ H D + EQ++ H P+T + G H PP + Q ++Q+ +
Sbjct: 246 ATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSK 305
>sp|P07476|INVO_HUMAN Involucrin
Length = 585
Score = 30.0 bits (66), Expect = 5.4
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +2
Query: 302 TMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLCK 430
T+P TL+ L E L PPP+ + QEQ+ + P+ P C+
Sbjct: 6 TLPVTLSPALSQELLKTVPPPV---NTHQEQMKQPTPLPPPCQ 45
>sp|Q8NVZ9|METK_STAAW S-adenosylmethionine synthetase (Methionine adenosyltransferase)
(AdoMet synthetase) (MAT)
sp|Q6G8E3|METK_STAAS S-adenosylmethionine synthetase (Methionine adenosyltransferase)
(AdoMet synthetase) (MAT)
sp|Q5HEY9|METK_STAAC S-adenosylmethionine synthetase (Methionine adenosyltransferase)
(AdoMet synthetase) (MAT)
Length = 397
Score = 30.0 bits (66), Expect = 5.4
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 170 TALLNINNPSNDNLGQINASTESHV-HKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGL 346
T +++ + + L QI ++HV + PE + NEQ+ F PT + G G GL
Sbjct: 196 TIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGL 255
>sp|Q6GFR6|METK_STAAR S-adenosylmethionine synthetase (Methionine adenosyltransferase)
(AdoMet synthetase) (MAT)
Length = 397
Score = 30.0 bits (66), Expect = 5.4
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 170 TALLNINNPSNDNLGQINASTESHV-HKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGL 346
T +++ + + L QI ++HV + PE + NEQ+ F PT + G G GL
Sbjct: 196 TIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGL 255
>sp|P66767|METK_STAAN S-adenosylmethionine synthetase (Methionine adenosyltransferase)
(AdoMet synthetase) (MAT)
sp|P66766|METK_STAAM S-adenosylmethionine synthetase (Methionine adenosyltransferase)
(AdoMet synthetase) (MAT)
Length = 398
Score = 30.0 bits (66), Expect = 5.4
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 170 TALLNINNPSNDNLGQINASTESHV-HKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGL 346
T +++ + + L QI ++HV + PE + NEQ+ F PT + G G GL
Sbjct: 196 TIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGL 255
>sp|Q9Y618|NCOR2_HUMAN Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of
retinoic acid and thyroid hormone receptor) (SMRT)
(SMRTe) (Thyroid-, retinoic-acid-receptor-associated
corepressor) (T3 receptor-associating factor) (TRAC) (CTG
repeat protein 26) (SMAP270)
Length = 2517
Score = 30.0 bits (66), Expect = 5.4
Identities = 14/35 (40%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Frame = +2
Query: 44 DINELYMLHHYMNPESNVIRPG-QVFTRPDITGLG 145
+IN+ H+ PE N+ +PG ++F P ITG G
Sbjct: 2289 EINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTG 2323
>sp|P14708|INVO_PONPY Involucrin
Length = 835
Score = 30.0 bits (66), Expect = 5.4
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +2
Query: 302 TMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLCK 430
T+P TL+ L E L PPP+ + QEQ+ + P+ P C+
Sbjct: 6 TLPVTLSPALSQELLKTVPPPV---NTQQEQMKQPTPLPPPCQ 45
>sp|P14591|INVO_PANPA Involucrin
Length = 560
Score = 30.0 bits (66), Expect = 5.4
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +2
Query: 302 TMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLCK 430
T+P TL+ L E L PPP+ + QEQ+ + P+ P C+
Sbjct: 6 TLPVTLSPALSQELLKTVPPPV---NTQQEQMKQPTPLPPPCQ 45
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,493,894
Number of Sequences: 369166
Number of extensions: 1124660
Number of successful extensions: 3510
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3423
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3509
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5316264630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)