Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_K09
(619 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q68FG0|HC127_MOUSE Hepatocellular carcinoma-associated a... 81 2e-15
sp|Q92833|JARD2_HUMAN Jumonji protein (Jumonji/ARID domain-... 33 0.76
sp|Q59268|MGM_EUBBA 2-methyleneglutarate mutase (Alpha-meth... 32 1.00
sp|Q54875|IGA1B_STRPN Immunoglobulin A1 protease precursor ... 32 1.7
sp|O15213|WDR46_HUMAN WD-repeat protein 46 (WD-repeat prote... 31 2.2
sp|P61591|MCPH1_GORGO Microcephalin 31 2.2
sp|P14591|INVO_PANPA Involucrin 31 2.2
sp|Q59947|IGA1_STRR6 Immunoglobulin A1 protease precursor (... 31 2.9
sp|P07476|INVO_HUMAN Involucrin 31 2.9
sp|Q97QP7|IGA1A_STRPN Immunoglobulin A1 protease precursor ... 31 2.9
>sp|Q68FG0|HC127_MOUSE Hepatocellular carcinoma-associated antigen 127 homolog
sp|Q9NQZ6|HC127_HUMAN Hepatocellular carcinoma-associated antigen 127
Length = 224
Score = 81.3 bits (199), Expect = 2e-15
Identities = 35/46 (76%), Positives = 38/46 (82%)
Frame = +3
Query: 309 TEGLHQQPPPMKKCQSCQEQIHRNAPICPLCKAKSRSINPKKPRKK 446
T QQPPPMK C SC +QIHRNAPICPLCKAKSRS NPKKP++K
Sbjct: 176 TATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRK 221
>sp|Q92833|JARD2_HUMAN Jumonji protein (Jumonji/ARID domain-containing protein 2)
Length = 1246
Score = 32.7 bits (73), Expect = 0.76
Identities = 19/87 (21%), Positives = 35/87 (40%)
Frame = +3
Query: 198 ASTESHVHKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHR 377
A+ H D + EQ++ H P+T + G H PP + Q ++Q+ +
Sbjct: 246 ATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSK 305
Query: 378 NAPICPLCKAKSRSINPKKPRKKPVSP 458
+ + + + KK R+ SP
Sbjct: 306 VNGVTRMSSLGAGVTSAKKMREVRPSP 332
>sp|Q59268|MGM_EUBBA 2-methyleneglutarate mutase (Alpha-methyleneglutarate mutase)
Length = 614
Score = 32.3 bits (72), Expect = 1.00
Identities = 15/54 (27%), Positives = 27/54 (50%)
Frame = +3
Query: 48 YMNPESNVIRPGQVFTRPDITGLGGSMNSFDPTALLNINNPSNDNLGQINASTE 209
+ NP N++ F+R +T G + + P A ++ P+ D++GQ TE
Sbjct: 290 FQNPPGNLVAEAAHFSRMAVTAKLGGADFYRPKAAESVGIPTGDSMGQAIWGTE 343
>sp|Q54875|IGA1B_STRPN Immunoglobulin A1 protease precursor (IgA1 protease) (IgA-specific
zinc metalloproteinase)
Length = 1927
Score = 31.6 bits (70), Expect = 1.7
Identities = 23/111 (20%), Positives = 45/111 (40%), Gaps = 14/111 (12%)
Frame = +3
Query: 189 QINASTESHVHKDKPETIKNEQSNFIHKPTMPATLA--------------GVLGTEGLHQ 326
Q A E + + PE + +++ +PT+P + V+ +G +
Sbjct: 411 QSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKGEPAVQPELPEAVVSDKGEPE 470
Query: 327 QPPPMKKCQSCQEQIHRNAPICPLCKAKSRSINPKKPRKKPVSPMEDKDEN 479
Q P+ + + EQ+ P+ K++ P+K + PV P E+ N
Sbjct: 471 QVAPLPEYKGNIEQVKPETPV-----EKTKEQGPEKTEEVPVKPTEETPVN 516
>sp|O15213|WDR46_HUMAN WD-repeat protein 46 (WD-repeat protein BING4)
Length = 610
Score = 31.2 bits (69), Expect = 2.2
Identities = 21/74 (28%), Positives = 33/74 (44%)
Frame = +3
Query: 222 KDKPETIKNEQSNFIHKPTMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLC 401
KDK +T + + + + T+P T G PP KK + + Q +NA I
Sbjct: 15 KDKLQTKRKKPRRYWEEETVPTTAGASPG-------PPRNKKNRELRPQRPKNAYILKKS 67
Query: 402 KAKSRSINPKKPRK 443
+ + PKKPR+
Sbjct: 68 RISKKPQVPKKpre 81
>sp|P61591|MCPH1_GORGO Microcephalin
Length = 835
Score = 31.2 bits (69), Expect = 2.2
Identities = 24/113 (21%), Positives = 44/113 (38%), Gaps = 16/113 (14%)
Frame = +3
Query: 216 VHKDKPETIKNEQSNFIHKPTMPATLAGVLGTEGLHQQP----------------PPMKK 347
V D+ + Q F K + TL+ + G +H +P PP +K
Sbjct: 311 VTPDQKQAAGMSQETFEEKYRLSPTLSSIKGHLLIHSRPRSSSVKRKRVSHGSHSPPKEK 370
Query: 348 CQSCQEQIHRNAPICPLCKAKSRSINPKKPRKKPVSPMEDKDENFYDYDTLNQ 506
C+ + P LC+++ R + P K +S E ++++ D L +
Sbjct: 371 CKRKRSIRRSIMPRLQLCRSEGRLQHVAGPALKALSCGESSYDDYFSPDNLKE 423
>sp|P14591|INVO_PANPA Involucrin
Length = 560
Score = 31.2 bits (69), Expect = 2.2
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +3
Query: 276 TMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLCKAKSRSINPKKPRKK 446
T+P TL+ L E L PPP+ + QEQ+ + P+ P C+ + + P K+
Sbjct: 6 TLPVTLSPALSQELLKTVPPPV---NTQQEQMKQPTPLPPPCQKMPVELPVEVPSKQ 59
>sp|Q59947|IGA1_STRR6 Immunoglobulin A1 protease precursor (IgA1 protease) (IgA-specific
zinc metalloproteinase)
Length = 1963
Score = 30.8 bits (68), Expect = 2.9
Identities = 23/111 (20%), Positives = 45/111 (40%), Gaps = 14/111 (12%)
Frame = +3
Query: 189 QINASTESHVHKDKPETIKNEQSNFIHKPTMPATLA--------------GVLGTEGLHQ 326
Q A E + + PE + +++ +PT+P + V+ +G +
Sbjct: 411 QSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPE 470
Query: 327 QPPPMKKCQSCQEQIHRNAPICPLCKAKSRSINPKKPRKKPVSPMEDKDEN 479
Q P+ + + EQ+ P+ K++ P+K + PV P E+ N
Sbjct: 471 QVAPLPEYKGNIEQVKPETPV-----EKTKEQGPEKTEEVPVKPTEETPVN 516
>sp|P07476|INVO_HUMAN Involucrin
Length = 585
Score = 30.8 bits (68), Expect = 2.9
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +3
Query: 276 TMPATLAGVLGTEGLHQQPPPMKKCQSCQEQIHRNAPICPLCKAKSRSINPKKPRKK 446
T+P TL+ L E L PPP+ + QEQ+ + P+ P C+ + + P K+
Sbjct: 6 TLPVTLSPALSQELLKTVPPPV---NTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQ 59
>sp|Q97QP7|IGA1A_STRPN Immunoglobulin A1 protease precursor (IgA1 protease) (IgA-specific
zinc metalloproteinase)
Length = 2004
Score = 30.8 bits (68), Expect = 2.9
Identities = 23/111 (20%), Positives = 45/111 (40%), Gaps = 14/111 (12%)
Frame = +3
Query: 189 QINASTESHVHKDKPETIKNEQSNFIHKPTMPATLA--------------GVLGTEGLHQ 326
Q A E + + PE + +++ +PT+P + V+ +G +
Sbjct: 411 QSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPE 470
Query: 327 QPPPMKKCQSCQEQIHRNAPICPLCKAKSRSINPKKPRKKPVSPMEDKDEN 479
Q P+ + + EQ+ P+ K++ P+K + PV P E+ N
Sbjct: 471 QVAPLPEYKGNIEQVKPETPV-----EKTKEQGPEKTEEVPVKPTEETPVN 516
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,939,270
Number of Sequences: 369166
Number of extensions: 1134997
Number of successful extensions: 3930
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3814
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3925
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4895780500
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)