Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00779 (1389 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P35224|CTNB_URECA Beta-catenin 139 3e-32 sp|P18824|ARM_DROME Armadillo segment polarity protein 137 7e-32 sp|Q02453|ARM_MUSDO Armadillo segment polarity protein 135 4e-31 sp|P35223|CTNB_TRIGR Beta-catenin 133 1e-30 sp|P26233|CTNB_XENLA Beta-catenin 133 1e-30 sp|Q02248|CTNB1_MOUSE Beta-catenin 133 1e-30 sp|P35222|CTNB1_HUMAN Beta-catenin 133 1e-30 sp|Q9WU82|CTNB1_RAT Beta-catenin 133 1e-30 sp|P14923|PLAK_HUMAN Junction plakoglobin (Desmoplakin III) 126 1e-28 sp|Q8SPJ1|PLAK_BOVIN Junction plakoglobin (Desmoplakin III) 126 1e-28
>sp|P35224|CTNB_URECA Beta-catenin Length = 818 Score = 139 bits (349), Expect = 3e-32 Identities = 85/251 (33%), Positives = 138/251 (54%), Gaps = 4/251 (1%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP +C LRH++SRH EAE AQ ++ GL +L++++ H P Sbjct: 484 EPAVCALRHLTSRHGEAEMAQNAVRLHYGLPVLVKLL-------------HPPS------ 524 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W LIKA++GLIRNLA+ P N P+RE G ++ L+ RA D + S + Sbjct: 525 -----RWPLIKAVVGLIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQRRATAGSGN 579 Query: 365 PKDKL----LEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCVFVIA 532 + +EEI+E + GALH++A++ R+ I + +C+ + A Sbjct: 580 TSAYVDGVRMEEIVEGTVGALHIMAREAHNRAVIRGL----------------NCISLFA 623 Query: 533 SLLFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYASAIL 712 LL++ +++IQRV AG+L E++ ++ G E+ I Q T L+E++HS NE ++TYA+A+L Sbjct: 624 QLLYSPIDNIQRVAAGVLCELAADKEGAEM-IEQEGTTAPLTELLHSRNEGVATYAAAVL 682 Query: 713 IRATEEKNKRY 745 R +E+K + Y Sbjct: 683 FRMSEDKPQDY 693
>sp|P18824|ARM_DROME Armadillo segment polarity protein Length = 843 Score = 137 bits (345), Expect = 7e-32 Identities = 90/282 (31%), Positives = 147/282 (52%), Gaps = 12/282 (4%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP +C LRH++SRH ++E AQ ++ GL ++++++ H P Sbjct: 470 EPAVCALRHLTSRHVDSELAQNAVRLNYGLSVIVKLL-------------HPPS------ 510 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W LIKA+IGLIRNLA+ P N P+RE G ++ L+ RA D + + + + Sbjct: 511 -----RWPLIKAVIGLIRNLALCPANHAPLREHGAIHHLVRLLMRAFQDTERQRSSIATT 565 Query: 365 PKDK--------LLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCV 520 + +EEI+E + GALH+LA++ R+ I QS + Sbjct: 566 GSQQPSAYADGVRMEEIVEGTVGALHILARESHNRA----------------LIRQQSVI 609 Query: 521 FVIASLLFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYA 700 + LLFN +E+IQRV AG+L E++ ++ G E II Q T L++++HS NE ++TYA Sbjct: 610 PIFVRLLFNEIENIQRVAAGVLCELAADKEGAE-IIEQEGATGPLTDLLHSRNEGVATYA 668 Query: 701 SAILIRATEEK----NKRYATSHNYNVAQNPNNLRNNLSISL 814 +A+L R +E+K KR + ++ + NN+ N + + Sbjct: 669 AAVLFRMSEDKPQDYKKRLSIELTNSLLREDNNIWANADLGM 710
>sp|Q02453|ARM_MUSDO Armadillo segment polarity protein Length = 813 Score = 135 bits (339), Expect = 4e-31 Identities = 89/283 (31%), Positives = 145/283 (51%), Gaps = 13/283 (4%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP +C LRH+++RH ++E AQ ++ GL ++++++ H P Sbjct: 460 EPAVCALRHLTTRHADSEMAQNAVRLNYGLSVIVKLL-------------HPPS------ 500 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W LIKA IGL+RNLA+ P N P+RE G ++ L+ RA D + + + + Sbjct: 501 -----RWPLIKAAIGLVRNLALCPANAAPLREHGAIHHLVRLLMRAFQDTERQRSSVATT 555 Query: 365 PKDK--------LLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCV 520 + +EEI+E + GALH+LA++ R+ I QS + Sbjct: 556 GSQQPAAYADGVRMEEIVEGTVGALHILARESHNRA----------------LIRQQSVI 599 Query: 521 FVIASLLFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYA 700 + LLFN +E+IQRV AG+L E++ ++ G E II Q T L++++HS NE ++TYA Sbjct: 600 PIFVRLLFNEIENIQRVAAGVLCELAADKEGAE-IIEQEGATGPLTDLLHSRNEGVATYA 658 Query: 701 SAILIRATEEKNKRYATSHNYNVAQN-----PNNLRNNLSISL 814 +A+L R +E+K + Y + + N NN+ N + L Sbjct: 659 AAVLFRMSEDKPQDYKKRLSIELTTNSLLREDNNIWGNADLGL 701
>sp|P35223|CTNB_TRIGR Beta-catenin Length = 820 Score = 133 bits (335), Expect = 1e-30 Identities = 83/253 (32%), Positives = 136/253 (53%), Gaps = 6/253 (2%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP +C LRH++SRH AE Q ++ G+ ++++++ H P Sbjct: 478 EPAVCALRHVTSRHPGAEMGQNTVRLNYGIPVIVKLL-------------HPPS------ 518 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W LIKA +GLIRNLA+ N P+RE+G ++ L+ RA D +++ S Sbjct: 519 -----RWPLIKATVGLIRNLALCSANHAPLREQGALHRLVQLLMRAHQDTQRRSSMGSTG 573 Query: 365 PK------DKLLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCVFV 526 + +E+I+E + GALH+LA+D R+ I + +C+ + Sbjct: 574 SQGGNYADGVRMEDIVEGTTGALHILARDSHNRALIQGL----------------NCIPL 617 Query: 527 IASLLFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYASA 706 LL+N++E+IQRV AG+L E+S E+ G E+ I Q T L+E++HS NE ++TYA+A Sbjct: 618 FVQLLYNNIENIQRVAAGVLSELSLEKQGAEM-IEQEGATAPLTELLHSRNEGVATYAAA 676 Query: 707 ILIRATEEKNKRY 745 +L R +++K + Y Sbjct: 677 VLYRMSDDKPQDY 689
>sp|P26233|CTNB_XENLA Beta-catenin Length = 781 Score = 133 bits (335), Expect = 1e-30 Identities = 86/250 (34%), Positives = 138/250 (55%), Gaps = 3/250 (1%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP IC LRH++SRH+EAE AQ ++ GL ++++++ H SH Sbjct: 462 EPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLL---------HPPSH--------- 503 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W LIKA +GLIRNLA+ P N P+RE+G ++ L+ RA D +T+ Sbjct: 504 ------WPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSIGGTQ 557 Query: 365 P---KDKLLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCVFVIAS 535 + +EEI+E GALH+LA+D I ++I+ I + + + Sbjct: 558 QQFVEGVRMEEIVEGCTGALHILARD--IHNRIV--------------IRGLNTIPLFVQ 601 Query: 536 LLFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYASAILI 715 LL++ +E+IQRV AG+L +V+ ++ E I ++ T L+E++HS NE ++TYA+A+L Sbjct: 602 LLYSPIENIQRVAAGVLCDVAQDKEAAEAIEAE-GATAPLTELLHSRNEGVATYAAAVLF 660 Query: 716 RATEEKNKRY 745 R +E+K + Y Sbjct: 661 RMSEDKPQDY 670
>sp|Q02248|CTNB1_MOUSE Beta-catenin Length = 781 Score = 133 bits (334), Expect = 1e-30 Identities = 85/250 (34%), Positives = 138/250 (55%), Gaps = 3/250 (1%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP IC LRH++SRH+EAE AQ ++ GL ++++++ H SH Sbjct: 462 EPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLL---------HPPSH--------- 503 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W LIKA +GLIRNLA+ P N P+RE+G ++ L+ RA D +T+ Sbjct: 504 ------WPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQ 557 Query: 365 P---KDKLLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCVFVIAS 535 + +EEI+E GALH+LA+D + ++I+ I + + + Sbjct: 558 QQFVEGVRMEEIVEGCTGALHILARD--VHNRIV--------------IRGLNTIPLFVQ 601 Query: 536 LLFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYASAILI 715 LL++ +E+IQRV AG+L E++ ++ E I ++ T L+E++HS NE ++TYA+A+L Sbjct: 602 LLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELLHSRNEGVATYAAAVLF 660 Query: 716 RATEEKNKRY 745 R +E+K + Y Sbjct: 661 RMSEDKPQDY 670
>sp|P35222|CTNB1_HUMAN Beta-catenin Length = 781 Score = 133 bits (334), Expect = 1e-30 Identities = 85/250 (34%), Positives = 138/250 (55%), Gaps = 3/250 (1%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP IC LRH++SRH+EAE AQ ++ GL ++++++ H SH Sbjct: 462 EPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLL---------HPPSH--------- 503 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W LIKA +GLIRNLA+ P N P+RE+G ++ L+ RA D +T+ Sbjct: 504 ------WPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQ 557 Query: 365 P---KDKLLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCVFVIAS 535 + +EEI+E GALH+LA+D + ++I+ I + + + Sbjct: 558 QQFVEGVRMEEIVEGCTGALHILARD--VHNRIV--------------IRGLNTIPLFVQ 601 Query: 536 LLFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYASAILI 715 LL++ +E+IQRV AG+L E++ ++ E I ++ T L+E++HS NE ++TYA+A+L Sbjct: 602 LLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELLHSRNEGVATYAAAVLF 660 Query: 716 RATEEKNKRY 745 R +E+K + Y Sbjct: 661 RMSEDKPQDY 670
>sp|Q9WU82|CTNB1_RAT Beta-catenin Length = 781 Score = 133 bits (334), Expect = 1e-30 Identities = 85/250 (34%), Positives = 138/250 (55%), Gaps = 3/250 (1%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP IC LRH++SRH+EAE AQ ++ GL ++++++ H SH Sbjct: 462 EPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLL---------HPPSH--------- 503 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W LIKA +GLIRNLA+ P N P+RE+G ++ L+ RA D +T+ Sbjct: 504 ------WPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQ 557 Query: 365 P---KDKLLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCVFVIAS 535 + +EEI+E GALH+LA+D + ++I+ I + + + Sbjct: 558 QQFVEGVRMEEIVEGCTGALHILARD--VHNRIV--------------IRGLNTIPLFVQ 601 Query: 536 LLFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYASAILI 715 LL++ +E+IQRV AG+L E++ ++ E I ++ T L+E++HS NE ++TYA+A+L Sbjct: 602 LLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELLHSRNEGVATYAAAVLF 660 Query: 716 RATEEKNKRY 745 R +E+K + Y Sbjct: 661 RMSEDKPQDY 670
>sp|P14923|PLAK_HUMAN Junction plakoglobin (Desmoplakin III) Length = 744 Score = 126 bits (317), Expect = 1e-28 Identities = 84/249 (33%), Positives = 129/249 (51%), Gaps = 2/249 (0%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP +C LRH++SRH EAE AQ S+ G+ +++++ PN Sbjct: 452 EPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQ----------------PN--- 492 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W L+KA IGLIRNLA+ P N P++E ++ L+ +A D A + Sbjct: 493 -----QWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQ 547 Query: 365 P--KDKLLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCVFVIASL 538 P +EEI+E GALH+LA+DP R +I RL P + L Sbjct: 548 PYTDGVRMEEIVEGCTGALHILARDPMNRMEIF------RLNTIP----------LFVQL 591 Query: 539 LFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYASAILIR 718 L++ +E+IQRV AG+L E++ ++ + I ++ + L E++HS NE +TYA+A+L R Sbjct: 592 LYSSVENIQRVAAGVLCELAQDKEAADAIDAE-GASAPLMELLHSRNEGTATYAAAVLFR 650 Query: 719 ATEEKNKRY 745 +E+KN Y Sbjct: 651 ISEDKNPDY 659
>sp|Q8SPJ1|PLAK_BOVIN Junction plakoglobin (Desmoplakin III) Length = 745 Score = 126 bits (317), Expect = 1e-28 Identities = 84/249 (33%), Positives = 129/249 (51%), Gaps = 2/249 (0%) Frame = +2 Query: 5 EPCICTLRHISSRHEEAEAAQASILHFQGLQILIRIIEMQLGPDLFHMQSHQPIMPNLFL 184 EP +C LRH++SRH EAE AQ S+ G+ +++++ PN Sbjct: 453 EPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQ----------------PN--- 493 Query: 185 SYYKINWSLIKAIIGLIRNLAMSPCNFVPIREKGFGWPMIVLINRAQIDLLNKTACASIS 364 W L+KA IGLIRNLA+ P N P++E ++ L+ +A D A + Sbjct: 494 -----QWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQ 548 Query: 365 P--KDKLLEEIIEVSCGALHMLAKDPGIRSQIISMKIWQRLINYPQQIGTQSCVFVIASL 538 P +EEI+E GALH+LA+DP R +I RL P + L Sbjct: 549 PYTDGVRMEEIVEGCTGALHILARDPMNRMEIF------RLNTIP----------LFVQL 592 Query: 539 LFNHLESIQRVTAGLLVEVSGERMGLELIISQIVITNKLSEMVHSNNEAISTYASAILIR 718 L++ +E+IQRV AG+L E++ ++ + I ++ + L E++HS NE +TYA+A+L R Sbjct: 593 LYSSVENIQRVAAGVLCELAQDKEAADAIDAE-GASAPLMELLHSRNEGTATYAAAVLFR 651 Query: 719 ATEEKNKRY 745 +E+KN Y Sbjct: 652 ISEDKNPDY 660
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 157,569,630 Number of Sequences: 369166 Number of extensions: 3193927 Number of successful extensions: 7644 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 7178 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7583 length of database: 68,354,980 effective HSP length: 114 effective length of database: 47,295,190 effective search space used: 16458726120 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)