Planaria EST Database

DrC_00771

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00771
         (666 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q26636|CATL_SARPE  Cathepsin L precursor [Contains: Cathe...   198   1e-50
sp|Q95029|CATL_DROME  Cathepsin L precursor (Cysteine protei...   192   9e-49
sp|P13277|CYSP1_HOMAM  Digestive cysteine proteinase 1 precu...   169   6e-42
sp|Q28944|CATL_PIG  Cathepsin L precursor [Contains: Catheps...   169   8e-42
sp|Q9GL24|CATL_CANFA  Cathepsin L precursor [Contains: Cathe...   169   8e-42
sp|P25975|CATL_BOVIN  Cathepsin L precursor [Contains: Cathe...   164   1e-40
sp|Q10991|CATL_SHEEP  Cathepsin L [Contains: Cathepsin L hea...   164   3e-40
sp|P25782|CYSP2_HOMAM  Digestive cysteine proteinase 2 precu...   162   6e-40
sp|P07154|CATL_RAT  Cathepsin L precursor (Major excreted pr...   160   3e-39
sp|P07711|CATL_HUMAN  Cathepsin L precursor (Major excreted ...   160   4e-39

>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 339

 Score =  198 bits (503), Expect = 1e-50
 Identities = 95/152 (62%), Positives = 112/152 (73%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           AF YI DNGGIDTE SYPY         D CHFN + +GATD GF+DIP+G+E  +K+AV
Sbjct: 194 AFRYIKDNGGIDTEKSYPYEG-----IDDSCHFNKATIGATDTGFVDIPEGDEEKMKKAV 248

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVKNS 374
           A +GP+SV IDAS  SF+ Y  GVY +  C  + LDHGVLVVGYG DE SG+ YWLVKNS
Sbjct: 249 ATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDE-SGMDYWLVKNS 307

Query: 375 WNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           W TTWG+ GYIKM R+ NN CGIATA+S+P V
Sbjct: 308 WGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339

>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
           L heavy chain; Cathepsin L light chain]
          Length = 341

 Score =  192 bits (487), Expect = 9e-49
 Identities = 95/152 (62%), Positives = 110/152 (72%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           AF YI DNGGIDTE SYPY +       D CHFN   VGATD GF DIP+G+E  + EAV
Sbjct: 196 AFRYIKDNGGIDTEKSYPYEA-----IDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAV 250

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVKNS 374
           A VGP+SV IDAS  SF+ Y  GVY +  C ++ LDHGVLVVG+G DE SG  YWLVKNS
Sbjct: 251 ATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNS 309

Query: 375 WNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           W TTWGD G+IKM R+  N CGIA+A+S+PLV
Sbjct: 310 WGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341

>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor
          Length = 322

 Score =  169 bits (428), Expect = 6e-42
 Identities = 83/152 (54%), Positives = 107/152 (70%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           A  Y+ DNGG+DTE SYPY +     R + C FN++ +GAT  G++ I +G+E+ LK A 
Sbjct: 178 AIMYVRDNGGVDTESSYPYEA-----RDNTCRFNSNTIGATCTGYVGIAQGSESALKTAT 232

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVKNS 374
             +GPISV IDAS  SF++Y +GVY + +CSS QLDH VL VGYG   + G  +WLVKNS
Sbjct: 233 RDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYG--SEGGQDFWLVKNS 290

Query: 375 WNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           W T+WG+SGYIKM R+ NN CGIAT A +P V
Sbjct: 291 WATSWGESGYIKMARNRNNNCGIATDACYPTV 322

>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  169 bits (427), Expect = 8e-42
 Identities = 82/154 (53%), Positives = 108/154 (70%), Gaps = 2/154 (1%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           AF Y+ DNGG+DTE SYPY+    GR ++ C +      A D GF+DIP+  + ++K AV
Sbjct: 186 AFQYVKDNGGLDTEESYPYL----GRETNSCTYKPECSAANDTGFVDIPQREKALMK-AV 240

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD--EDSGIPYWLVK 368
           A VGPISV IDA   SF+ Y+SG+Y D +CSS+ LDHGVLVVGYG +  + +   +W+VK
Sbjct: 241 ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 300

Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           NSW   WG +GY+KM +D NN CGI+TAAS+P V
Sbjct: 301 NSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334

>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 333

 Score =  169 bits (427), Expect = 8e-42
 Identities = 82/153 (53%), Positives = 109/153 (71%), Gaps = 1/153 (0%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           AF Y+ DNGG+D+E SYPY+    GR ++ C++      A D GF+D+P+  + ++K AV
Sbjct: 186 AFRYVKDNGGLDSEESYPYL----GRDTETCNYKPECSAANDTGFVDLPQREKALMK-AV 240

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD-EDSGIPYWLVKN 371
           A +GPISV IDA   SF+ Y+SG+Y D +CSS+ LDHGVLVVGYG +  DS   +W+VKN
Sbjct: 241 ATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKN 300

Query: 372 SWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           SW   WG +GY+KM +D NN CGIATAAS+P V
Sbjct: 301 SWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333

>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  164 bits (416), Expect = 1e-40
 Identities = 81/154 (52%), Positives = 107/154 (69%), Gaps = 2/154 (1%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           AF YI DNGG+D+E SYPY++  T    + C++      A D GF+DIP+  + ++K AV
Sbjct: 186 AFQYIKDNGGLDSEESYPYLATDT----NSCNYKPECSAANDTGFVDIPQREKALMK-AV 240

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD--EDSGIPYWLVK 368
           A VGPISV IDA   SF+ Y+SG+Y D +CS + LDHGVLVVGYG +  + +   +W+VK
Sbjct: 241 ATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVK 300

Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           NSW   WG +GY+KM +D NN CGIATAAS+P V
Sbjct: 301 NSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334

>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
           chain]
          Length = 217

 Score =  164 bits (414), Expect = 3e-40
 Identities = 82/152 (53%), Positives = 105/152 (69%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           AF YI +NGG+D+E SYPY +  T      C++      A D GF+DIP+  + ++K AV
Sbjct: 73  AFQYIKENGGLDSEESYPYEATDTS-----CNYKPEYSAAKDTGFVDIPQREKALMK-AV 126

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVKNS 374
           A VGPISV IDA   SF+ Y+SG+Y D +CSS+ LDHGVLVVGYG  E +   +W+VKNS
Sbjct: 127 ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGF-EGTNNKFWIVKNS 185

Query: 375 WNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           W   WG+ GY+KM +D NN CGIATAAS+P V
Sbjct: 186 WGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217

>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
          Length = 323

 Score =  162 bits (411), Expect = 6e-40
 Identities = 83/154 (53%), Positives = 106/154 (68%)
 Frame = +3

Query: 9   HEAFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKE 188
           ++AF YI  N GIDTE +YPY +     R   C F++++V AT  G  +I  G+ET L++
Sbjct: 177 NDAFDYIKANNGIDTEAAYPYEA-----RDGSCRFDSNSVAATCSGHTNIASGSETGLQQ 231

Query: 189 AVALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVK 368
           AV  +GPISV IDA+  SF+ Y SGVY + +CS   LDH VL VGYG   + G  +WLVK
Sbjct: 232 AVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYG--SEGGQDFWLVK 289

Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           NSW T+WGD+GYIKM R+ NN CGIAT AS+PLV
Sbjct: 290 NSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323

>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
           protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
           Cathepsin L light chain]
          Length = 334

 Score =  160 bits (405), Expect = 3e-39
 Identities = 81/154 (52%), Positives = 105/154 (68%), Gaps = 2/154 (1%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           AF YI +NGG+D+E SYPY +     +   C + A    A D GF+DIP+  + ++K AV
Sbjct: 186 AFQYIKENGGLDSEESYPYEA-----KDGSCKYRAEYAVANDTGFVDIPQQEKALMK-AV 239

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD--EDSGIPYWLVK 368
           A VGPISV +DAS  S + Y SG+Y + NCSS+ LDHGVLVVGYG +  + +   YWLVK
Sbjct: 240 ATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVK 299

Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           NSW   WG  GYIK+ +D NN CG+ATAAS+P+V
Sbjct: 300 NSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333

>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
           Cathepsin L heavy chain; Cathepsin L light chain]
          Length = 333

 Score =  160 bits (404), Expect = 4e-39
 Identities = 81/154 (52%), Positives = 102/154 (66%), Gaps = 2/154 (1%)
 Frame = +3

Query: 15  AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
           AF Y+ DNGG+D+E SYPY + +     + C +N     A D GF+DIPK  + ++K AV
Sbjct: 186 AFQYVQDNGGLDSEESYPYEATE-----ESCKYNPKYSVANDTGFVDIPKQEKALMK-AV 239

Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD--EDSGIPYWLVK 368
           A VGPISV IDA   SF  Y+ G+Y + +CSSE +DHGVLVVGYG +  E     YWLVK
Sbjct: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299

Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
           NSW   WG  GY+KM +D  N CGIA+AAS+P V
Sbjct: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,793,335
Number of Sequences: 369166
Number of extensions: 1562495
Number of successful extensions: 4671
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4203
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4324
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5608903050
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00771

  1. Dr_sW_016_G23
  2. Dr_sW_019_P06