Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_P06
(666 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 198 1e-50
sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 192 9e-49
sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 169 6e-42
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 169 8e-42
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 169 8e-42
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 164 1e-40
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 164 3e-40
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 162 6e-40
sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 160 3e-39
sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 160 4e-39
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 198 bits (503), Expect = 1e-50
Identities = 95/152 (62%), Positives = 112/152 (73%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
AF YI DNGGIDTE SYPY D CHFN + +GATD GF+DIP+G+E +K+AV
Sbjct: 194 AFRYIKDNGGIDTEKSYPYEG-----IDDSCHFNKATIGATDTGFVDIPEGDEEKMKKAV 248
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVKNS 374
A +GP+SV IDAS SF+ Y GVY + C + LDHGVLVVGYG DE SG+ YWLVKNS
Sbjct: 249 ATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDE-SGMDYWLVKNS 307
Query: 375 WNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
W TTWG+ GYIKM R+ NN CGIATA+S+P V
Sbjct: 308 WGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
L heavy chain; Cathepsin L light chain]
Length = 341
Score = 192 bits (487), Expect = 9e-49
Identities = 95/152 (62%), Positives = 110/152 (72%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
AF YI DNGGIDTE SYPY + D CHFN VGATD GF DIP+G+E + EAV
Sbjct: 196 AFRYIKDNGGIDTEKSYPYEA-----IDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAV 250
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVKNS 374
A VGP+SV IDAS SF+ Y GVY + C ++ LDHGVLVVG+G DE SG YWLVKNS
Sbjct: 251 ATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNS 309
Query: 375 WNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
W TTWGD G+IKM R+ N CGIA+A+S+PLV
Sbjct: 310 WGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor
Length = 322
Score = 169 bits (428), Expect = 6e-42
Identities = 83/152 (54%), Positives = 107/152 (70%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
A Y+ DNGG+DTE SYPY + R + C FN++ +GAT G++ I +G+E+ LK A
Sbjct: 178 AIMYVRDNGGVDTESSYPYEA-----RDNTCRFNSNTIGATCTGYVGIAQGSESALKTAT 232
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVKNS 374
+GPISV IDAS SF++Y +GVY + +CSS QLDH VL VGYG + G +WLVKNS
Sbjct: 233 RDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYG--SEGGQDFWLVKNS 290
Query: 375 WNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
W T+WG+SGYIKM R+ NN CGIAT A +P V
Sbjct: 291 WATSWGESGYIKMARNRNNNCGIATDACYPTV 322
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 169 bits (427), Expect = 8e-42
Identities = 82/154 (53%), Positives = 108/154 (70%), Gaps = 2/154 (1%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
AF Y+ DNGG+DTE SYPY+ GR ++ C + A D GF+DIP+ + ++K AV
Sbjct: 186 AFQYVKDNGGLDTEESYPYL----GRETNSCTYKPECSAANDTGFVDIPQREKALMK-AV 240
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD--EDSGIPYWLVK 368
A VGPISV IDA SF+ Y+SG+Y D +CSS+ LDHGVLVVGYG + + + +W+VK
Sbjct: 241 ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVK 300
Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
NSW WG +GY+KM +D NN CGI+TAAS+P V
Sbjct: 301 NSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 169 bits (427), Expect = 8e-42
Identities = 82/153 (53%), Positives = 109/153 (71%), Gaps = 1/153 (0%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
AF Y+ DNGG+D+E SYPY+ GR ++ C++ A D GF+D+P+ + ++K AV
Sbjct: 186 AFRYVKDNGGLDSEESYPYL----GRDTETCNYKPECSAANDTGFVDLPQREKALMK-AV 240
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD-EDSGIPYWLVKN 371
A +GPISV IDA SF+ Y+SG+Y D +CSS+ LDHGVLVVGYG + DS +W+VKN
Sbjct: 241 ATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKN 300
Query: 372 SWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
SW WG +GY+KM +D NN CGIATAAS+P V
Sbjct: 301 SWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 164 bits (416), Expect = 1e-40
Identities = 81/154 (52%), Positives = 107/154 (69%), Gaps = 2/154 (1%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
AF YI DNGG+D+E SYPY++ T + C++ A D GF+DIP+ + ++K AV
Sbjct: 186 AFQYIKDNGGLDSEESYPYLATDT----NSCNYKPECSAANDTGFVDIPQREKALMK-AV 240
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD--EDSGIPYWLVK 368
A VGPISV IDA SF+ Y+SG+Y D +CS + LDHGVLVVGYG + + + +W+VK
Sbjct: 241 ATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVK 300
Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
NSW WG +GY+KM +D NN CGIATAAS+P V
Sbjct: 301 NSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 164 bits (414), Expect = 3e-40
Identities = 82/152 (53%), Positives = 105/152 (69%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
AF YI +NGG+D+E SYPY + T C++ A D GF+DIP+ + ++K AV
Sbjct: 73 AFQYIKENGGLDSEESYPYEATDTS-----CNYKPEYSAAKDTGFVDIPQREKALMK-AV 126
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVKNS 374
A VGPISV IDA SF+ Y+SG+Y D +CSS+ LDHGVLVVGYG E + +W+VKNS
Sbjct: 127 ATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGF-EGTNNKFWIVKNS 185
Query: 375 WNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
W WG+ GY+KM +D NN CGIATAAS+P V
Sbjct: 186 WGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 162 bits (411), Expect = 6e-40
Identities = 83/154 (53%), Positives = 106/154 (68%)
Frame = +3
Query: 9 HEAFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKE 188
++AF YI N GIDTE +YPY + R C F++++V AT G +I G+ET L++
Sbjct: 177 NDAFDYIKANNGIDTEAAYPYEA-----RDGSCRFDSNSVAATCSGHTNIASGSETGLQQ 231
Query: 189 AVALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVDEDSGIPYWLVK 368
AV +GPISV IDA+ SF+ Y SGVY + +CS LDH VL VGYG + G +WLVK
Sbjct: 232 AVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYG--SEGGQDFWLVK 289
Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
NSW T+WGD+GYIKM R+ NN CGIAT AS+PLV
Sbjct: 290 NSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 160 bits (405), Expect = 3e-39
Identities = 81/154 (52%), Positives = 105/154 (68%), Gaps = 2/154 (1%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
AF YI +NGG+D+E SYPY + + C + A A D GF+DIP+ + ++K AV
Sbjct: 186 AFQYIKENGGLDSEESYPYEA-----KDGSCKYRAEYAVANDTGFVDIPQQEKALMK-AV 239
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD--EDSGIPYWLVK 368
A VGPISV +DAS S + Y SG+Y + NCSS+ LDHGVLVVGYG + + + YWLVK
Sbjct: 240 ATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVK 299
Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
NSW WG GYIK+ +D NN CG+ATAAS+P+V
Sbjct: 300 NSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
Cathepsin L heavy chain; Cathepsin L light chain]
Length = 333
Score = 160 bits (404), Expect = 4e-39
Identities = 81/154 (52%), Positives = 102/154 (66%), Gaps = 2/154 (1%)
Frame = +3
Query: 15 AFGYISDNGGIDTEISYPYISGKTGRRSDKCHFNASNVGATDFGFIDIPKGNETMLKEAV 194
AF Y+ DNGG+D+E SYPY + + + C +N A D GF+DIPK + ++K AV
Sbjct: 186 AFQYVQDNGGLDSEESYPYEATE-----ESCKYNPKYSVANDTGFVDIPKQEKALMK-AV 239
Query: 195 ALVGPISVGIDASQLSFRNYRSGVYEDINCSSEQLDHGVLVVGYGVD--EDSGIPYWLVK 368
A VGPISV IDA SF Y+ G+Y + +CSSE +DHGVLVVGYG + E YWLVK
Sbjct: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299
Query: 369 NSWNTTWGDSGYIKMRRDFNNMCGIATAASFPLV 470
NSW WG GY+KM +D N CGIA+AAS+P V
Sbjct: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,793,335
Number of Sequences: 369166
Number of extensions: 1562495
Number of successful extensions: 4671
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4203
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4324
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5608903050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)