Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00740 (538 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9Y3E5|PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondri... 118 8e-27 sp|Q8R2Y8|PTH2_MOUSE Peptidyl-tRNA hydrolase 2, mitochondri... 117 2e-26 sp|O13830|PTH2_SCHPO Probable peptidyl-tRNA hydrolase 2 (PT... 109 4e-24 sp|O97067|PTH2_DROME Probable peptidyl-tRNA hydrolase 2 (PT... 96 7e-20 sp|O74017|PTH_PYRHO Peptidyl-tRNA hydrolase (PTH) 92 6e-19 sp|Q976I0|PTH_SULTO Peptidyl-tRNA hydrolase (PTH) 88 1e-17 sp|Q8U0N0|PTH_PYRFU Peptidyl-tRNA hydrolase (PTH) 87 3e-17 sp|Q9V108|PTH_PYRAB Peptidyl-tRNA hydrolase (PTH) 86 4e-17 sp|Q5JDB8|PTH_PYRKO Peptidyl-tRNA hydrolase (PTH) 86 8e-17 sp|Q980V1|PTH_SULSO Peptidyl-tRNA hydrolase (PTH) 84 3e-16
>sp|Q9Y3E5|PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondrial precursor (PTH 2) (Bcl-2 inhibitor of transcription 1) Length = 179 Score = 118 bits (296), Expect = 8e-27 Identities = 63/117 (53%), Positives = 75/117 (64%) Frame = +2 Query: 152 SKEIKLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVD 331 S E K+IL R VAAQC+HAAV YK R P+M+ WE CGQPK+VVK Sbjct: 62 SGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAP 121 Query: 332 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 EE+L L A L L LI+D G+TQ+ G+ TVLGIGPGPA LIDK+TG+LKL Sbjct: 122 DEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 178
>sp|Q8R2Y8|PTH2_MOUSE Peptidyl-tRNA hydrolase 2, mitochondrial precursor (PTH 2) Length = 181 Score = 117 bits (292), Expect = 2e-26 Identities = 59/117 (50%), Positives = 78/117 (66%) Frame = +2 Query: 152 SKEIKLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVD 331 S E K+IL R VAAQC+HAAV YK R +P+++ WE CGQPK+VVK Sbjct: 64 SGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRSPQVLKEWEYCGQPKVVVKAP 123 Query: 332 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 E++L +L A +L L LI+D G+TQ++ G+ TVLGIGPGP LID++TG+LKL Sbjct: 124 DEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKL 180
>sp|O13830|PTH2_SCHPO Probable peptidyl-tRNA hydrolase 2 (PTH 2) Length = 205 Score = 109 bits (273), Expect = 4e-24 Identities = 54/115 (46%), Positives = 74/115 (64%) Frame = +2 Query: 158 EIKLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTE 337 + K++L R +AAQCAHAA+ CYK P ++ WE GQ KI ++ TE Sbjct: 90 QTKMVLVVRTDLGMTKGKIAAQCAHAALACYKIASAVDPDLVRIWENAGQAKITLQAQTE 149 Query: 338 ESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 E+L LQ A SL L +I D G+TQ+ SG++TVLGIGPGP S+I+++TG+LKL Sbjct: 150 ETLELLQAQAMSLGLCARVIHDAGRTQIASGSATVLGIGPGPVSVINEVTGSLKL 204
>sp|O97067|PTH2_DROME Probable peptidyl-tRNA hydrolase 2 (PTH 2) Length = 186 Score = 95.5 bits (236), Expect = 7e-20 Identities = 45/113 (39%), Positives = 70/113 (61%) Frame = +2 Query: 164 KLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 343 K++L R +AAQC H AVG Y+ + P+++ WE CG KI V+V++E Sbjct: 73 KMVLVVRNDLKMGKGKIAAQCGHGAVGAYQRAVVRTPRLLRSWENCGCAKIAVRVESEAE 132 Query: 344 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 L ++++A L LIRD G+TQ+++ + TVL +GP A+ ID++TG+LKL Sbjct: 133 LMAIKKEAERQQLNTCLIRDAGRTQIEANSKTVLAVGPAAAADIDRVTGHLKL 185
>sp|O74017|PTH_PYRHO Peptidyl-tRNA hydrolase (PTH) Length = 121 Score = 92.4 bits (228), Expect = 6e-19 Identities = 50/113 (44%), Positives = 66/113 (58%) Frame = +2 Query: 164 KLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 343 K ++ AR +AAQ AH AV + + W GQ K+VVKV++EE Sbjct: 8 KQVIVARADLKLSKGKLAAQVAHGAVTAAFEAYKKKREWFEAWFREGQKKVVVKVESEEE 67 Query: 344 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 LFKL+ +A L L N LIRD G T++ GT TVL +GP P ++DK+TGNLKL Sbjct: 68 LFKLKAEAEKLGLPNALIRDAGLTEIPPGTVTVLAVGPAPEEIVDKVTGNLKL 120
>sp|Q976I0|PTH_SULTO Peptidyl-tRNA hydrolase (PTH) Length = 121 Score = 88.2 bits (217), Expect = 1e-17 Identities = 51/117 (43%), Positives = 67/117 (57%), Gaps = 4/117 (3%) Frame = +2 Query: 164 KLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEIC----GQPKIVVKVD 331 K+++ R +AAQ AHAAV L S+ + W GQPKIVVKV Sbjct: 4 KMVIVVRTDLDMGKGKIAAQVAHAAVSLVLDILNSSNSLWKEWLYKWLEEGQPKIVVKVP 63 Query: 332 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 + + L K + A LNL +I+D GKTQ++ GT T +GIGP P L+DKITG+LKL Sbjct: 64 SLDELNKRYEKAIELNLPTTIIQDAGKTQIEPGTITCIGIGPAPVELVDKITGDLKL 120
>sp|Q8U0N0|PTH_PYRFU Peptidyl-tRNA hydrolase (PTH) Length = 119 Score = 86.7 bits (213), Expect = 3e-17 Identities = 48/113 (42%), Positives = 62/113 (54%) Frame = +2 Query: 164 KLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 343 K ++ AR +A Q AH AV + + W GQ K+VVK EE Sbjct: 6 KQVIVARSDLKLSKGKLAVQVAHGAVTAAFEAYKKKREWFEAWFREGQKKVVVKAQNEEE 65 Query: 344 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 LFKL+ +A L L LIRD G T++ GT TVL IGPGP ++DK+TG+LKL Sbjct: 66 LFKLKSEAEKLGLPTALIRDAGLTEIPPGTITVLAIGPGPEEVVDKVTGHLKL 118
>sp|Q9V108|PTH_PYRAB Peptidyl-tRNA hydrolase (PTH) Length = 121 Score = 86.3 bits (212), Expect = 4e-17 Identities = 47/115 (40%), Positives = 66/115 (57%) Frame = +2 Query: 158 EIKLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTE 337 + K ++ R +A Q AH AV + + W GQ K+VVKV++ Sbjct: 6 KFKQVIVVRKDLKLSKGKLAVQVAHGAVTAAFKAYKEKREWFEKWFHEGQKKVVVKVESL 65 Query: 338 ESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 + LFKL+ +A LNL LI+D G T++ GT TVL IGPGP+ +IDK+TG+LKL Sbjct: 66 DELFKLKAEAEKLNLPTALIQDAGLTEIPPGTITVLAIGPGPSEIIDKVTGHLKL 120
>sp|Q5JDB8|PTH_PYRKO Peptidyl-tRNA hydrolase (PTH) Length = 118 Score = 85.5 bits (210), Expect = 8e-17 Identities = 47/113 (41%), Positives = 62/113 (54%) Frame = +2 Query: 164 KLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 343 K ++ AR A Q AH AV + P+ W GQ K+VVK + E Sbjct: 5 KQVIVARKDLKLSKGKFAVQVAHGAVTAAIKAQKEKPEWFKAWFHEGQKKVVVKAENLEE 64 Query: 344 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 LFKL+ +A L L LI+D G T++ GT TVL IGPGP ++DK+TG+LKL Sbjct: 65 LFKLKAEAEKLGLPTALIKDAGLTEIPPGTVTVLAIGPGPEEVVDKVTGHLKL 117
>sp|Q980V1|PTH_SULSO Peptidyl-tRNA hydrolase (PTH) Length = 120 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/118 (40%), Positives = 69/118 (58%), Gaps = 4/118 (3%) Frame = +2 Query: 161 IKLILDARXXXXXXXXXVAAQCAHAAVGCYKCGLRSA----PKMINYWEICGQPKIVVKV 328 IK+++ R +AAQ AHAAV + S + +N W GQPKI+VKV Sbjct: 2 IKMVIVVRSDIKMGKGKIAAQVAHAAVTLVVSIINSNNLRWKEWLNEWLHQGQPKIIVKV 61 Query: 329 DTEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502 ++ + + + A ++NL +I D GKTQ++ GT T LGIGP P +L+D ITG+LKL Sbjct: 62 NSLDEIISRAKKAETMNLPFSIIEDAGKTQLEPGTITCLGIGPAPENLVDSITGDLKL 119
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 53,414,344 Number of Sequences: 369166 Number of extensions: 948457 Number of successful extensions: 2292 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2230 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2281 length of database: 68,354,980 effective HSP length: 103 effective length of database: 49,327,275 effective search space used: 3699545625 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)