Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_E20
(534 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y3E5|PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondri... 142 4e-34
sp|Q8R2Y8|PTH2_MOUSE Peptidyl-tRNA hydrolase 2, mitochondri... 142 7e-34
sp|O13830|PTH2_SCHPO Probable peptidyl-tRNA hydrolase 2 (PT... 130 3e-30
sp|O97067|PTH2_DROME Probable peptidyl-tRNA hydrolase 2 (PT... 119 4e-27
sp|O74017|PTH_PYRHO Peptidyl-tRNA hydrolase (PTH) 111 1e-24
sp|Q976I0|PTH_SULTO Peptidyl-tRNA hydrolase (PTH) 109 4e-24
sp|Q980V1|PTH_SULSO Peptidyl-tRNA hydrolase (PTH) 107 2e-23
sp|Q9V108|PTH_PYRAB Peptidyl-tRNA hydrolase (PTH) 106 4e-23
sp|Q8U0N0|PTH_PYRFU Peptidyl-tRNA hydrolase (PTH) 104 2e-22
sp|O27732|PTH_METTH Peptidyl-tRNA hydrolase (PTH) 103 3e-22
>sp|Q9Y3E5|PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondrial precursor (PTH 2) (Bcl-2
inhibitor of transcription 1)
Length = 179
Score = 142 bits (359), Expect = 4e-34
Identities = 73/118 (61%), Positives = 86/118 (72%)
Frame = +2
Query: 152 SEEIKLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVD 331
S E K+ILVVR DLKMGKGKVAAQC+HAAV YK R P+M+ WE CGQPK+VVK
Sbjct: 62 SGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAP 121
Query: 332 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKLF 505
EE+L L A L L LI+D G+TQ+ G+ TVLGIGPGPA LIDK+TG+LKL+
Sbjct: 122 DEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY 179
>sp|Q8R2Y8|PTH2_MOUSE Peptidyl-tRNA hydrolase 2, mitochondrial precursor (PTH 2)
Length = 181
Score = 142 bits (357), Expect = 7e-34
Identities = 69/118 (58%), Positives = 89/118 (75%)
Frame = +2
Query: 152 SEEIKLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVD 331
S E K+ILVVR DLKMGKGKVAAQC+HAAV YK R +P+++ WE CGQPK+VVK
Sbjct: 64 SGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRSPQVLKEWEYCGQPKVVVKAP 123
Query: 332 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKLF 505
E++L +L A +L L LI+D G+TQ++ G+ TVLGIGPGP LID++TG+LKL+
Sbjct: 124 DEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKLY 181
>sp|O13830|PTH2_SCHPO Probable peptidyl-tRNA hydrolase 2 (PTH 2)
Length = 205
Score = 130 bits (326), Expect = 3e-30
Identities = 63/116 (54%), Positives = 83/116 (71%)
Frame = +2
Query: 158 EIKLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTE 337
+ K++LVVR DL M KGK+AAQCAHAA+ CYK P ++ WE GQ KI ++ TE
Sbjct: 90 QTKMVLVVRTDLGMTKGKIAAQCAHAALACYKIASAVDPDLVRIWENAGQAKITLQAQTE 149
Query: 338 ESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKLF 505
E+L LQ A SL L +I D G+TQ+ SG++TVLGIGPGP S+I+++TG+LKLF
Sbjct: 150 ETLELLQAQAMSLGLCARVIHDAGRTQIASGSATVLGIGPGPVSVINEVTGSLKLF 205
>sp|O97067|PTH2_DROME Probable peptidyl-tRNA hydrolase 2 (PTH 2)
Length = 186
Score = 119 bits (299), Expect = 4e-27
Identities = 55/117 (47%), Positives = 82/117 (70%)
Frame = +2
Query: 152 SEEIKLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVD 331
++ K++LVVR DLKMGKGK+AAQC H AVG Y+ + P+++ WE CG KI V+V+
Sbjct: 69 NDNFKMVLVVRNDLKMGKGKIAAQCGHGAVGAYQRAVVRTPRLLRSWENCGCAKIAVRVE 128
Query: 332 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502
+E L ++++A L LIRD G+TQ+++ + TVL +GP A+ ID++TG+LKL
Sbjct: 129 SEAELMAIKKEAERQQLNTCLIRDAGRTQIEANSKTVLAVGPAAAADIDRVTGHLKL 185
>sp|O74017|PTH_PYRHO Peptidyl-tRNA hydrolase (PTH)
Length = 121
Score = 111 bits (277), Expect = 1e-24
Identities = 57/113 (50%), Positives = 74/113 (65%)
Frame = +2
Query: 164 KLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 343
K ++V RADLK+ KGK+AAQ AH AV + + W GQ K+VVKV++EE
Sbjct: 8 KQVIVARADLKLSKGKLAAQVAHGAVTAAFEAYKKKREWFEAWFREGQKKVVVKVESEEE 67
Query: 344 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502
LFKL+ +A L L N LIRD G T++ GT TVL +GP P ++DK+TGNLKL
Sbjct: 68 LFKLKAEAEKLGLPNALIRDAGLTEIPPGTVTVLAVGPAPEEIVDKVTGNLKL 120
>sp|Q976I0|PTH_SULTO Peptidyl-tRNA hydrolase (PTH)
Length = 121
Score = 109 bits (273), Expect = 4e-24
Identities = 60/117 (51%), Positives = 76/117 (64%), Gaps = 4/117 (3%)
Frame = +2
Query: 164 KLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEIC----GQPKIVVKVD 331
K+++VVR DL MGKGK+AAQ AHAAV L S+ + W GQPKIVVKV
Sbjct: 4 KMVIVVRTDLDMGKGKIAAQVAHAAVSLVLDILNSSNSLWKEWLYKWLEEGQPKIVVKVP 63
Query: 332 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502
+ + L K + A LNL +I+D GKTQ++ GT T +GIGP P L+DKITG+LKL
Sbjct: 64 SLDELNKRYEKAIELNLPTTIIQDAGKTQIEPGTITCIGIGPAPVELVDKITGDLKL 120
>sp|Q980V1|PTH_SULSO Peptidyl-tRNA hydrolase (PTH)
Length = 120
Score = 107 bits (266), Expect = 2e-23
Identities = 57/118 (48%), Positives = 80/118 (67%), Gaps = 4/118 (3%)
Frame = +2
Query: 161 IKLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSA----PKMINYWEICGQPKIVVKV 328
IK+++VVR+D+KMGKGK+AAQ AHAAV + S + +N W GQPKI+VKV
Sbjct: 2 IKMVIVVRSDIKMGKGKIAAQVAHAAVTLVVSIINSNNLRWKEWLNEWLHQGQPKIIVKV 61
Query: 329 DTEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502
++ + + + A ++NL +I D GKTQ++ GT T LGIGP P +L+D ITG+LKL
Sbjct: 62 NSLDEIISRAKKAETMNLPFSIIEDAGKTQLEPGTITCLGIGPAPENLVDSITGDLKL 119
>sp|Q9V108|PTH_PYRAB Peptidyl-tRNA hydrolase (PTH)
Length = 121
Score = 106 bits (264), Expect = 4e-23
Identities = 55/115 (47%), Positives = 75/115 (65%)
Frame = +2
Query: 158 EIKLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTE 337
+ K ++VVR DLK+ KGK+A Q AH AV + + W GQ K+VVKV++
Sbjct: 6 KFKQVIVVRKDLKLSKGKLAVQVAHGAVTAAFKAYKEKREWFEKWFHEGQKKVVVKVESL 65
Query: 338 ESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502
+ LFKL+ +A LNL LI+D G T++ GT TVL IGPGP+ +IDK+TG+LKL
Sbjct: 66 DELFKLKAEAEKLNLPTALIQDAGLTEIPPGTITVLAIGPGPSEIIDKVTGHLKL 120
>sp|Q8U0N0|PTH_PYRFU Peptidyl-tRNA hydrolase (PTH)
Length = 119
Score = 104 bits (259), Expect = 2e-22
Identities = 54/113 (47%), Positives = 70/113 (61%)
Frame = +2
Query: 164 KLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 343
K ++V R+DLK+ KGK+A Q AH AV + + W GQ K+VVK EE
Sbjct: 6 KQVIVARSDLKLSKGKLAVQVAHGAVTAAFEAYKKKREWFEAWFREGQKKVVVKAQNEEE 65
Query: 344 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502
LFKL+ +A L L LIRD G T++ GT TVL IGPGP ++DK+TG+LKL
Sbjct: 66 LFKLKSEAEKLGLPTALIRDAGLTEIPPGTITVLAIGPGPEEVVDKVTGHLKL 118
>sp|O27732|PTH_METTH Peptidyl-tRNA hydrolase (PTH)
Length = 112
Score = 103 bits (257), Expect = 3e-22
Identities = 51/114 (44%), Positives = 75/114 (65%)
Frame = +2
Query: 161 IKLILVVRADLKMGKGKVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEE 340
+K +++VR+DLKMGKGK+AAQ HA++G +K R+ I WE+ G K++V V++ +
Sbjct: 1 MKQVIIVRSDLKMGKGKIAAQACHASIGSFK---RTEEDKIRKWELEGSKKVIVSVNSLD 57
Query: 341 SLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 502
L ++ + + N L+RD G TQ+ +GT T LGIGP IDKITG+LKL
Sbjct: 58 ELLEIYRAVKEAGISNYLVRDAGHTQIPAGTITCLGIGPDDDEKIDKITGDLKL 111
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,963,824
Number of Sequences: 369166
Number of extensions: 940707
Number of successful extensions: 2211
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2156
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2195
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3650218350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)