Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_C06
(507 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y3E5|PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondri... 117 1e-26
sp|Q8R2Y8|PTH2_MOUSE Peptidyl-tRNA hydrolase 2, mitochondri... 116 3e-26
sp|O13830|PTH2_SCHPO Probable peptidyl-tRNA hydrolase 2 (PT... 108 5e-24
sp|O97067|PTH2_DROME Probable peptidyl-tRNA hydrolase 2 (PT... 95 1e-19
sp|O74017|PTH_PYRHO Peptidyl-tRNA hydrolase (PTH) 91 1e-18
sp|Q976I0|PTH_SULTO Peptidyl-tRNA hydrolase (PTH) 87 2e-17
sp|Q9V108|PTH_PYRAB Peptidyl-tRNA hydrolase (PTH) 86 7e-17
sp|Q8U0N0|PTH_PYRFU Peptidyl-tRNA hydrolase (PTH) 86 7e-17
sp|Q5JDB8|PTH_PYRKO Peptidyl-tRNA hydrolase (PTH) 84 1e-16
sp|Q980V1|PTH_SULSO Peptidyl-tRNA hydrolase (PTH) 83 4e-16
>sp|Q9Y3E5|PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondrial precursor (PTH 2) (Bcl-2
inhibitor of transcription 1)
Length = 179
Score = 117 bits (294), Expect = 1e-26
Identities = 63/117 (53%), Positives = 75/117 (64%)
Frame = +1
Query: 121 SKEIKLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVD 300
S E K+IL R VAAQC+HAAV YK R P+M+ WE CGQPK+VVK
Sbjct: 62 SGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAP 121
Query: 301 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
EE+L L A L L LI+D G+TQ+ G+ TVLGIGPGPA LIDK+TG+LKL
Sbjct: 122 DEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKL 178
>sp|Q8R2Y8|PTH2_MOUSE Peptidyl-tRNA hydrolase 2, mitochondrial precursor (PTH 2)
Length = 181
Score = 116 bits (290), Expect = 3e-26
Identities = 59/117 (50%), Positives = 78/117 (66%)
Frame = +1
Query: 121 SKEIKLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVD 300
S E K+IL R VAAQC+HAAV YK R +P+++ WE CGQPK+VVK
Sbjct: 64 SGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRSPQVLKEWEYCGQPKVVVKAP 123
Query: 301 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
E++L +L A +L L LI+D G+TQ++ G+ TVLGIGPGP LID++TG+LKL
Sbjct: 124 DEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKL 180
>sp|O13830|PTH2_SCHPO Probable peptidyl-tRNA hydrolase 2 (PTH 2)
Length = 205
Score = 108 bits (271), Expect = 5e-24
Identities = 54/115 (46%), Positives = 74/115 (64%)
Frame = +1
Query: 127 EIKLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTE 306
+ K++L R +AAQCAHAA+ CYK P ++ WE GQ KI ++ TE
Sbjct: 90 QTKMVLVVRTDLGMTKGKIAAQCAHAALACYKIASAVDPDLVRIWENAGQAKITLQAQTE 149
Query: 307 ESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
E+L LQ A SL L +I D G+TQ+ SG++TVLGIGPGP S+I+++TG+LKL
Sbjct: 150 ETLELLQAQAMSLGLCARVIHDAGRTQIASGSATVLGIGPGPVSVINEVTGSLKL 204
>sp|O97067|PTH2_DROME Probable peptidyl-tRNA hydrolase 2 (PTH 2)
Length = 186
Score = 94.7 bits (234), Expect = 1e-19
Identities = 45/113 (39%), Positives = 70/113 (61%)
Frame = +1
Query: 133 KLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 312
K++L R +AAQC H AVG Y+ + P+++ WE CG KI V+V++E
Sbjct: 73 KMVLVVRNDLKMGKGKIAAQCGHGAVGAYQRAVVRTPRLLRSWENCGCAKIAVRVESEAE 132
Query: 313 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
L ++++A L LIRD G+TQ+++ + TVL +GP A+ ID++TG+LKL
Sbjct: 133 LMAIKKEAERQQLNTCLIRDAGRTQIEANSKTVLAVGPAAAADIDRVTGHLKL 185
>sp|O74017|PTH_PYRHO Peptidyl-tRNA hydrolase (PTH)
Length = 121
Score = 91.3 bits (225), Expect = 1e-18
Identities = 49/113 (43%), Positives = 66/113 (58%)
Frame = +1
Query: 133 KLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 312
K ++ +R +AAQ AH AV + + W GQ K+VVKV++EE
Sbjct: 8 KQVIVARADLKLSKGKLAAQVAHGAVTAAFEAYKKKREWFEAWFREGQKKVVVKVESEEE 67
Query: 313 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
LFKL+ +A L L N LIRD G T++ GT TVL +GP P ++DK+TGNLKL
Sbjct: 68 LFKLKAEAEKLGLPNALIRDAGLTEIPPGTVTVLAVGPAPEEIVDKVTGNLKL 120
>sp|Q976I0|PTH_SULTO Peptidyl-tRNA hydrolase (PTH)
Length = 121
Score = 87.4 bits (215), Expect = 2e-17
Identities = 51/117 (43%), Positives = 67/117 (57%), Gaps = 4/117 (3%)
Frame = +1
Query: 133 KLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEIC----GQPKIVVKVD 300
K+++ R +AAQ AHAAV L S+ + W GQPKIVVKV
Sbjct: 4 KMVIVVRTDLDMGKGKIAAQVAHAAVSLVLDILNSSNSLWKEWLYKWLEEGQPKIVVKVP 63
Query: 301 TEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
+ + L K + A LNL +I+D GKTQ++ GT T +GIGP P L+DKITG+LKL
Sbjct: 64 SLDELNKRYEKAIELNLPTTIIQDAGKTQIEPGTITCIGIGPAPVELVDKITGDLKL 120
>sp|Q9V108|PTH_PYRAB Peptidyl-tRNA hydrolase (PTH)
Length = 121
Score = 85.5 bits (210), Expect = 7e-17
Identities = 45/97 (46%), Positives = 61/97 (62%)
Frame = +1
Query: 181 VAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEESLFKLQQDAFSLNLLNV 360
+A Q AH AV + + W GQ K+VVKV++ + LFKL+ +A LNL
Sbjct: 24 LAVQVAHGAVTAAFKAYKEKREWFEKWFHEGQKKVVVKVESLDELFKLKAEAEKLNLPTA 83
Query: 361 LIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
LI+D G T++ GT TVL IGPGP+ +IDK+TG+LKL
Sbjct: 84 LIQDAGLTEIPPGTITVLAIGPGPSEIIDKVTGHLKL 120
>sp|Q8U0N0|PTH_PYRFU Peptidyl-tRNA hydrolase (PTH)
Length = 119
Score = 85.5 bits (210), Expect = 7e-17
Identities = 47/113 (41%), Positives = 62/113 (54%)
Frame = +1
Query: 133 KLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 312
K ++ +R +A Q AH AV + + W GQ K+VVK EE
Sbjct: 6 KQVIVARSDLKLSKGKLAVQVAHGAVTAAFEAYKKKREWFEAWFREGQKKVVVKAQNEEE 65
Query: 313 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
LFKL+ +A L L LIRD G T++ GT TVL IGPGP ++DK+TG+LKL
Sbjct: 66 LFKLKSEAEKLGLPTALIRDAGLTEIPPGTITVLAIGPGPEEVVDKVTGHLKL 118
>sp|Q5JDB8|PTH_PYRKO Peptidyl-tRNA hydrolase (PTH)
Length = 118
Score = 84.3 bits (207), Expect = 1e-16
Identities = 46/113 (40%), Positives = 62/113 (54%)
Frame = +1
Query: 133 KLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSAPKMINYWEICGQPKIVVKVDTEES 312
K ++ +R A Q AH AV + P+ W GQ K+VVK + E
Sbjct: 5 KQVIVARKDLKLSKGKFAVQVAHGAVTAAIKAQKEKPEWFKAWFHEGQKKVVVKAENLEE 64
Query: 313 LFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
LFKL+ +A L L LI+D G T++ GT TVL IGPGP ++DK+TG+LKL
Sbjct: 65 LFKLKAEAEKLGLPTALIKDAGLTEIPPGTVTVLAIGPGPEEVVDKVTGHLKL 117
>sp|Q980V1|PTH_SULSO Peptidyl-tRNA hydrolase (PTH)
Length = 120
Score = 82.8 bits (203), Expect = 4e-16
Identities = 48/118 (40%), Positives = 69/118 (58%), Gaps = 4/118 (3%)
Frame = +1
Query: 130 IKLILDSRXXXXXXXXXVAAQCAHAAVGCYKCGLRSA----PKMINYWEICGQPKIVVKV 297
IK+++ R +AAQ AHAAV + S + +N W GQPKI+VKV
Sbjct: 2 IKMVIVVRSDIKMGKGKIAAQVAHAAVTLVVSIINSNNLRWKEWLNEWLHQGQPKIIVKV 61
Query: 298 DTEESLFKLQQDAFSLNLLNVLIRDKGKTQVDSGTSTVLGIGPGPASLIDKITGNLKL 471
++ + + + A ++NL +I D GKTQ++ GT T LGIGP P +L+D ITG+LKL
Sbjct: 62 NSLDEIISRAKKAETMNLPFSIIEDAGKTQLEPGTITCLGIGPAPENLVDSITGDLKL 119
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,127,206
Number of Sequences: 369166
Number of extensions: 938477
Number of successful extensions: 2369
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2306
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2360
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3206272875
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)