Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00724 (663 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q6PFS7|APG3L_BRARE Autophagy protein 3-like (APG3-like) 192 5e-49 sp|Q9NT62|APG3L_HUMAN Autophagy protein 3-like (APG3-like) ... 188 1e-47 sp|Q9CPX6|APG3L_MOUSE Autophagy protein 3-like (APG3-like) 188 1e-47 sp|Q6AZ50|APG3L_RAT Autophagy protein 3-like (APG3-like) (P... 187 2e-47 sp|Q5I0S6|APG3L_XENTR Autophagy protein 3-like (APG3-like) 187 2e-47 sp|Q6GQE7|APG3L_XENLA Autophagy protein 3-like (APG3-like) 186 6e-47 sp|O43035|ATG3_SCHPO Autophagy-related protein 3 (Autophagy... 108 1e-23 sp|Q6CL19|ATG3_KLULA Autophagy-related protein 3 (Autophagy... 102 9e-22 sp|Q5K9X6|ATG3_CRYNE Autophagy-related protein 3 (Autophagy... 101 2e-21 sp|Q755K1|ATG3_ASHGO Autophagy-related protein 3 (Autophagy... 98 2e-20
>sp|Q6PFS7|APG3L_BRARE Autophagy protein 3-like (APG3-like) Length = 317 Score = 192 bits (489), Expect = 5e-49 Identities = 101/152 (66%), Positives = 113/152 (74%) Frame = +1 Query: 121 LEDDDLIAPANQSAMTSKEIIKVADSCQSDIVQTRTYDLQITYDKLYQTCRLWLCGYDED 300 LE DD ++ A SK K + I+QTRTYDL ITYDK YQT RLWL GYDED Sbjct: 169 LETDDATLDTSKMADLSKT--KAEAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDED 226 Query: 301 RSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGA 480 R LT +QM+ED SQDHVKKTVT+E HP+LP M SVHPCR AEVMKK+IE VAEGG Sbjct: 227 RQPLTVDQMYEDISQDHVKKTVTIENHPNLPPPA-MCSVHPCRHAEVMKKIIETVAEGGG 285 Query: 481 VLGVHQYIVIFLKFVQAVIPTIEYDYTRNFNM 576 LGVH Y++IFLKFVQAVIPTIEYDYTR+F M Sbjct: 286 ELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM 317
>sp|Q9NT62|APG3L_HUMAN Autophagy protein 3-like (APG3-like) (hApg3) (PC3-96 protein) Length = 314 Score = 188 bits (477), Expect = 1e-47 Identities = 95/139 (68%), Positives = 107/139 (76%), Gaps = 8/139 (5%) Frame = +1 Query: 184 KVADSCQSD--------IVQTRTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDF 339 K+ ++C++ I+QTRTYDL ITYDK YQT RLWL GYDE R LT E M+ED Sbjct: 177 KIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDI 236 Query: 340 SQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGAVLGVHQYIVIFLK 519 SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE VAEGG LGVH Y++IFLK Sbjct: 237 SQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLK 295 Query: 520 FVQAVIPTIEYDYTRNFNM 576 FVQAVIPTIEYDYTR+F M Sbjct: 296 FVQAVIPTIEYDYTRHFTM 314
>sp|Q9CPX6|APG3L_MOUSE Autophagy protein 3-like (APG3-like) Length = 314 Score = 188 bits (477), Expect = 1e-47 Identities = 95/139 (68%), Positives = 107/139 (76%), Gaps = 8/139 (5%) Frame = +1 Query: 184 KVADSCQSD--------IVQTRTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDF 339 K+ ++C++ I+QTRTYDL ITYDK YQT RLWL GYDE R LT E M+ED Sbjct: 177 KIVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDI 236 Query: 340 SQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGAVLGVHQYIVIFLK 519 SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE VAEGG LGVH Y++IFLK Sbjct: 237 SQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLK 295 Query: 520 FVQAVIPTIEYDYTRNFNM 576 FVQAVIPTIEYDYTR+F M Sbjct: 296 FVQAVIPTIEYDYTRHFTM 314
>sp|Q6AZ50|APG3L_RAT Autophagy protein 3-like (APG3-like) (Preconditioning-inducible gene 1 protein) Length = 314 Score = 187 bits (476), Expect = 2e-47 Identities = 97/147 (65%), Positives = 113/147 (76%), Gaps = 5/147 (3%) Frame = +1 Query: 151 NQSAMTSKEIIKV----ADSCQSD-IVQTRTYDLQITYDKLYQTCRLWLCGYDEDRSLLT 315 +++ + ++ I++ AD+ D I+QTRTYDL ITYDK YQT RLWL GYDE R LT Sbjct: 169 DEATLDTRRIVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLT 228 Query: 316 EEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGAVLGVH 495 E M+ED SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE VAEGG LGVH Sbjct: 229 VEHMYEDISQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETVAEGGGELGVH 287 Query: 496 QYIVIFLKFVQAVIPTIEYDYTRNFNM 576 Y++IFLKFVQAVIPTIEYDYTR+F M Sbjct: 288 MYLLIFLKFVQAVIPTIEYDYTRHFTM 314
>sp|Q5I0S6|APG3L_XENTR Autophagy protein 3-like (APG3-like) Length = 312 Score = 187 bits (475), Expect = 2e-47 Identities = 99/148 (66%), Positives = 108/148 (72%), Gaps = 6/148 (4%) Frame = +1 Query: 151 NQSAMTSKEIIKVADSCQSD------IVQTRTYDLQITYDKLYQTCRLWLCGYDEDRSLL 312 N A IK A ++D I+QTRTYDL ITYDK YQT RLWL GYDE R L Sbjct: 166 NDDATVDTSKIKEACKPKADLGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRRPL 225 Query: 313 TEEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGAVLGV 492 T E M+ED SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE VAEGG LGV Sbjct: 226 TVENMYEDISQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETVAEGGGELGV 284 Query: 493 HQYIVIFLKFVQAVIPTIEYDYTRNFNM 576 H Y++IFLKFVQAVIPTIEYDYTR+F M Sbjct: 285 HMYLLIFLKFVQAVIPTIEYDYTRHFTM 312
>sp|Q6GQE7|APG3L_XENLA Autophagy protein 3-like (APG3-like) Length = 313 Score = 186 bits (471), Expect = 6e-47 Identities = 101/157 (64%), Positives = 114/157 (72%), Gaps = 6/157 (3%) Frame = +1 Query: 124 EDDDLIAPANQSAMTSKEIIKVADSCQSD------IVQTRTYDLQITYDKLYQTCRLWLC 285 E+ L+ + + TSK IK A ++D I+QTRTYDL ITYDK YQT RLWL Sbjct: 160 EESGLLENDDATVDTSK--IKEACKPKADLGGEDAILQTRTYDLYITYDKYYQTPRLWLF 217 Query: 286 GYDEDRSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAV 465 GYDE R L E M+ED SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE V Sbjct: 218 GYDEQRRPLAVENMYEDISQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETV 276 Query: 466 AEGGAVLGVHQYIVIFLKFVQAVIPTIEYDYTRNFNM 576 AEGG LGVH Y++IFLKFVQAVIPTIEYDYTR+F M Sbjct: 277 AEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM 313
>sp|O43035|ATG3_SCHPO Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme atg3) Length = 275 Score = 108 bits (270), Expect = 1e-23 Identities = 56/113 (49%), Positives = 72/113 (63%) Frame = +1 Query: 223 RTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGV 402 R YDL I YDK Y+T RL+L G++ LLT + ++ED S +H KTVTME PH Sbjct: 160 RYYDLYIVYDKYYRTPRLFLRGWNAGGQLLTMKDIYEDVSGEHAGKTVTMEPFPHYHSHN 219 Query: 403 LMASVHPCRQAEVMKKLIEAVAEGGAVLGVHQYIVIFLKFVQAVIPTIEYDYT 561 MASVHPC+ A V+ KLI+ E + V QY+V+FLKFV ++P E DYT Sbjct: 220 TMASVHPCKHASVLLKLIKQHRERNDPIRVDQYMVLFLKFVSTMLPYFEIDYT 272
>sp|Q6CL19|ATG3_KLULA Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme ATG3) Length = 302 Score = 102 bits (254), Expect = 9e-22 Identities = 55/136 (40%), Positives = 75/136 (55%), Gaps = 23/136 (16%) Frame = +1 Query: 223 RTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGV 402 R YDL ITY Y+ +++LCGYD D + L+ +QMFED + D+ KT T+E P L G Sbjct: 163 RFYDLYITYSTSYRVPKMYLCGYDNDGTPLSPDQMFEDIAADYRSKTATIEPLPFLKGNN 222 Query: 403 LMASVHPCRQAEVMKKLIEAVAEGGAV-----------------------LGVHQYIVIF 513 + S+HPC+ A VMK L+E V + L V QY+V+F Sbjct: 223 ISVSIHPCKHANVMKVLMEKVRSSRSRARKVDPQTTDEDWEDLQSDVDDGLRVDQYLVVF 282 Query: 514 LKFVQAVIPTIEYDYT 561 LKF+ +V P IE+DYT Sbjct: 283 LKFITSVTPGIEHDYT 298
>sp|Q5K9X6|ATG3_CRYNE Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme ATG3) Length = 385 Score = 101 bits (252), Expect = 2e-21 Identities = 69/205 (33%), Positives = 93/205 (45%), Gaps = 58/205 (28%) Frame = +1 Query: 121 LEDDDLIAPANQSAMTSKEIIKVADSCQSDIVQTRTYDLQITYDKLYQTCRLWLCGYDED 300 LEDD + + S +V + +++Q RTYD I+YDK YQT R WL GYDE Sbjct: 184 LEDDAAVRIVHPSEA------EVNSTAGKNLLQVRTYDCIISYDKHYQTPRFWLFGYDEH 237 Query: 301 RSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAV----- 465 ++ LT Q+F+D DH KT+TME PH G +ASVHPC+ A VMKK I+ + Sbjct: 238 KNPLTPAQVFQDVPADHAFKTMTMESFPH--SGAQLASVHPCKHASVMKKFIDRMEAAQG 295 Query: 466 ----------------------------------------AEGGAVLGVHQ--------- 498 GG+V V + Sbjct: 296 PAPTAEPETISSTSGTSGSAGGKEEKEKKKKWGLGSMVRKVTGGSVPKVEKDKDEVVTGV 355 Query: 499 ----YIVIFLKFVQAVIPTIEYDYT 561 Y+VIFLKF+ +++PTIE D T Sbjct: 356 PVDFYLVIFLKFIASIVPTIEVDST 380
>sp|Q755K1|ATG3_ASHGO Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme ATG3) Length = 282 Score = 97.8 bits (242), Expect = 2e-20 Identities = 57/151 (37%), Positives = 81/151 (53%), Gaps = 29/151 (19%) Frame = +1 Query: 196 SCQSDIVQ-----TRTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDFSQDHVKK 360 S + DI+Q TR YDL ITY Y+ +++L G++ D + LT +QMF+D + D+ K Sbjct: 128 SGEQDIIQLRPSHTRFYDLYITYSTSYRVPKMYLVGFNNDGTPLTPQQMFQDIAPDYRTK 187 Query: 361 TVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVA------------------------ 468 T T+E P V+ S+HPCR A VM+ L+E V Sbjct: 188 TATIEKLPFFKSAVVAVSIHPCRHANVMRVLMEKVRAAKQKPVEEEQPDGpreDWEDLQD 247 Query: 469 EGGAVLGVHQYIVIFLKFVQAVIPTIEYDYT 561 E + L V QY+V+FLKF+ +V P IE+DYT Sbjct: 248 EVDSSLRVVQYLVVFLKFITSVTPGIEHDYT 278
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 64,207,353 Number of Sequences: 369166 Number of extensions: 1112001 Number of successful extensions: 2630 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2547 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2617 length of database: 68,354,980 effective HSP length: 106 effective length of database: 48,773,070 effective search space used: 5560129980 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)