Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_O03
(663 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6PFS7|APG3L_BRARE Autophagy protein 3-like (APG3-like) 192 5e-49
sp|Q9NT62|APG3L_HUMAN Autophagy protein 3-like (APG3-like) ... 188 1e-47
sp|Q9CPX6|APG3L_MOUSE Autophagy protein 3-like (APG3-like) 188 1e-47
sp|Q6AZ50|APG3L_RAT Autophagy protein 3-like (APG3-like) (P... 187 2e-47
sp|Q5I0S6|APG3L_XENTR Autophagy protein 3-like (APG3-like) 187 2e-47
sp|Q6GQE7|APG3L_XENLA Autophagy protein 3-like (APG3-like) 186 6e-47
sp|O43035|ATG3_SCHPO Autophagy-related protein 3 (Autophagy... 108 1e-23
sp|Q6CL19|ATG3_KLULA Autophagy-related protein 3 (Autophagy... 102 9e-22
sp|Q5K9X6|ATG3_CRYNE Autophagy-related protein 3 (Autophagy... 101 2e-21
sp|Q755K1|ATG3_ASHGO Autophagy-related protein 3 (Autophagy... 98 2e-20
>sp|Q6PFS7|APG3L_BRARE Autophagy protein 3-like (APG3-like)
Length = 317
Score = 192 bits (489), Expect = 5e-49
Identities = 101/152 (66%), Positives = 113/152 (74%)
Frame = +1
Query: 121 LEDDDLIAPANQSAMTSKEIIKVADSCQSDIVQTRTYDLQITYDKLYQTCRLWLCGYDED 300
LE DD ++ A SK K + I+QTRTYDL ITYDK YQT RLWL GYDED
Sbjct: 169 LETDDATLDTSKMADLSKT--KAEAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDED 226
Query: 301 RSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGA 480
R LT +QM+ED SQDHVKKTVT+E HP+LP M SVHPCR AEVMKK+IE VAEGG
Sbjct: 227 RQPLTVDQMYEDISQDHVKKTVTIENHPNLPPPA-MCSVHPCRHAEVMKKIIETVAEGGG 285
Query: 481 VLGVHQYIVIFLKFVQAVIPTIEYDYTRNFNM 576
LGVH Y++IFLKFVQAVIPTIEYDYTR+F M
Sbjct: 286 ELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM 317
>sp|Q9NT62|APG3L_HUMAN Autophagy protein 3-like (APG3-like) (hApg3) (PC3-96 protein)
Length = 314
Score = 188 bits (477), Expect = 1e-47
Identities = 95/139 (68%), Positives = 107/139 (76%), Gaps = 8/139 (5%)
Frame = +1
Query: 184 KVADSCQSD--------IVQTRTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDF 339
K+ ++C++ I+QTRTYDL ITYDK YQT RLWL GYDE R LT E M+ED
Sbjct: 177 KIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDI 236
Query: 340 SQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGAVLGVHQYIVIFLK 519
SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE VAEGG LGVH Y++IFLK
Sbjct: 237 SQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLK 295
Query: 520 FVQAVIPTIEYDYTRNFNM 576
FVQAVIPTIEYDYTR+F M
Sbjct: 296 FVQAVIPTIEYDYTRHFTM 314
>sp|Q9CPX6|APG3L_MOUSE Autophagy protein 3-like (APG3-like)
Length = 314
Score = 188 bits (477), Expect = 1e-47
Identities = 95/139 (68%), Positives = 107/139 (76%), Gaps = 8/139 (5%)
Frame = +1
Query: 184 KVADSCQSD--------IVQTRTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDF 339
K+ ++C++ I+QTRTYDL ITYDK YQT RLWL GYDE R LT E M+ED
Sbjct: 177 KIVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDI 236
Query: 340 SQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGAVLGVHQYIVIFLK 519
SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE VAEGG LGVH Y++IFLK
Sbjct: 237 SQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLK 295
Query: 520 FVQAVIPTIEYDYTRNFNM 576
FVQAVIPTIEYDYTR+F M
Sbjct: 296 FVQAVIPTIEYDYTRHFTM 314
>sp|Q6AZ50|APG3L_RAT Autophagy protein 3-like (APG3-like) (Preconditioning-inducible
gene 1 protein)
Length = 314
Score = 187 bits (476), Expect = 2e-47
Identities = 97/147 (65%), Positives = 113/147 (76%), Gaps = 5/147 (3%)
Frame = +1
Query: 151 NQSAMTSKEIIKV----ADSCQSD-IVQTRTYDLQITYDKLYQTCRLWLCGYDEDRSLLT 315
+++ + ++ I++ AD+ D I+QTRTYDL ITYDK YQT RLWL GYDE R LT
Sbjct: 169 DEATLDTRRIVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLT 228
Query: 316 EEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGAVLGVH 495
E M+ED SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE VAEGG LGVH
Sbjct: 229 VEHMYEDISQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETVAEGGGELGVH 287
Query: 496 QYIVIFLKFVQAVIPTIEYDYTRNFNM 576
Y++IFLKFVQAVIPTIEYDYTR+F M
Sbjct: 288 MYLLIFLKFVQAVIPTIEYDYTRHFTM 314
>sp|Q5I0S6|APG3L_XENTR Autophagy protein 3-like (APG3-like)
Length = 312
Score = 187 bits (475), Expect = 2e-47
Identities = 99/148 (66%), Positives = 108/148 (72%), Gaps = 6/148 (4%)
Frame = +1
Query: 151 NQSAMTSKEIIKVADSCQSD------IVQTRTYDLQITYDKLYQTCRLWLCGYDEDRSLL 312
N A IK A ++D I+QTRTYDL ITYDK YQT RLWL GYDE R L
Sbjct: 166 NDDATVDTSKIKEACKPKADLGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRRPL 225
Query: 313 TEEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVAEGGAVLGV 492
T E M+ED SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE VAEGG LGV
Sbjct: 226 TVENMYEDISQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETVAEGGGELGV 284
Query: 493 HQYIVIFLKFVQAVIPTIEYDYTRNFNM 576
H Y++IFLKFVQAVIPTIEYDYTR+F M
Sbjct: 285 HMYLLIFLKFVQAVIPTIEYDYTRHFTM 312
>sp|Q6GQE7|APG3L_XENLA Autophagy protein 3-like (APG3-like)
Length = 313
Score = 186 bits (471), Expect = 6e-47
Identities = 101/157 (64%), Positives = 114/157 (72%), Gaps = 6/157 (3%)
Frame = +1
Query: 124 EDDDLIAPANQSAMTSKEIIKVADSCQSD------IVQTRTYDLQITYDKLYQTCRLWLC 285
E+ L+ + + TSK IK A ++D I+QTRTYDL ITYDK YQT RLWL
Sbjct: 160 EESGLLENDDATVDTSK--IKEACKPKADLGGEDAILQTRTYDLYITYDKYYQTPRLWLF 217
Query: 286 GYDEDRSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAV 465
GYDE R L E M+ED SQDHVKKTVT+E HPHLP M SVHPCR AEVMKK+IE V
Sbjct: 218 GYDEQRRPLAVENMYEDISQDHVKKTVTIENHPHLPPPP-MCSVHPCRHAEVMKKIIETV 276
Query: 466 AEGGAVLGVHQYIVIFLKFVQAVIPTIEYDYTRNFNM 576
AEGG LGVH Y++IFLKFVQAVIPTIEYDYTR+F M
Sbjct: 277 AEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM 313
>sp|O43035|ATG3_SCHPO Autophagy-related protein 3 (Autophagy-related E2-like conjugation
enzyme atg3)
Length = 275
Score = 108 bits (270), Expect = 1e-23
Identities = 56/113 (49%), Positives = 72/113 (63%)
Frame = +1
Query: 223 RTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGV 402
R YDL I YDK Y+T RL+L G++ LLT + ++ED S +H KTVTME PH
Sbjct: 160 RYYDLYIVYDKYYRTPRLFLRGWNAGGQLLTMKDIYEDVSGEHAGKTVTMEPFPHYHSHN 219
Query: 403 LMASVHPCRQAEVMKKLIEAVAEGGAVLGVHQYIVIFLKFVQAVIPTIEYDYT 561
MASVHPC+ A V+ KLI+ E + V QY+V+FLKFV ++P E DYT
Sbjct: 220 TMASVHPCKHASVLLKLIKQHRERNDPIRVDQYMVLFLKFVSTMLPYFEIDYT 272
>sp|Q6CL19|ATG3_KLULA Autophagy-related protein 3 (Autophagy-related E2-like conjugation
enzyme ATG3)
Length = 302
Score = 102 bits (254), Expect = 9e-22
Identities = 55/136 (40%), Positives = 75/136 (55%), Gaps = 23/136 (16%)
Frame = +1
Query: 223 RTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGV 402
R YDL ITY Y+ +++LCGYD D + L+ +QMFED + D+ KT T+E P L G
Sbjct: 163 RFYDLYITYSTSYRVPKMYLCGYDNDGTPLSPDQMFEDIAADYRSKTATIEPLPFLKGNN 222
Query: 403 LMASVHPCRQAEVMKKLIEAVAEGGAV-----------------------LGVHQYIVIF 513
+ S+HPC+ A VMK L+E V + L V QY+V+F
Sbjct: 223 ISVSIHPCKHANVMKVLMEKVRSSRSRARKVDPQTTDEDWEDLQSDVDDGLRVDQYLVVF 282
Query: 514 LKFVQAVIPTIEYDYT 561
LKF+ +V P IE+DYT
Sbjct: 283 LKFITSVTPGIEHDYT 298
>sp|Q5K9X6|ATG3_CRYNE Autophagy-related protein 3 (Autophagy-related E2-like conjugation
enzyme ATG3)
Length = 385
Score = 101 bits (252), Expect = 2e-21
Identities = 69/205 (33%), Positives = 93/205 (45%), Gaps = 58/205 (28%)
Frame = +1
Query: 121 LEDDDLIAPANQSAMTSKEIIKVADSCQSDIVQTRTYDLQITYDKLYQTCRLWLCGYDED 300
LEDD + + S +V + +++Q RTYD I+YDK YQT R WL GYDE
Sbjct: 184 LEDDAAVRIVHPSEA------EVNSTAGKNLLQVRTYDCIISYDKHYQTPRFWLFGYDEH 237
Query: 301 RSLLTEEQMFEDFSQDHVKKTVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAV----- 465
++ LT Q+F+D DH KT+TME PH G +ASVHPC+ A VMKK I+ +
Sbjct: 238 KNPLTPAQVFQDVPADHAFKTMTMESFPH--SGAQLASVHPCKHASVMKKFIDRMEAAQG 295
Query: 466 ----------------------------------------AEGGAVLGVHQ--------- 498
GG+V V +
Sbjct: 296 PAPTAEPETISSTSGTSGSAGGKEEKEKKKKWGLGSMVRKVTGGSVPKVEKDKDEVVTGV 355
Query: 499 ----YIVIFLKFVQAVIPTIEYDYT 561
Y+VIFLKF+ +++PTIE D T
Sbjct: 356 PVDFYLVIFLKFIASIVPTIEVDST 380
>sp|Q755K1|ATG3_ASHGO Autophagy-related protein 3 (Autophagy-related E2-like conjugation
enzyme ATG3)
Length = 282
Score = 97.8 bits (242), Expect = 2e-20
Identities = 57/151 (37%), Positives = 81/151 (53%), Gaps = 29/151 (19%)
Frame = +1
Query: 196 SCQSDIVQ-----TRTYDLQITYDKLYQTCRLWLCGYDEDRSLLTEEQMFEDFSQDHVKK 360
S + DI+Q TR YDL ITY Y+ +++L G++ D + LT +QMF+D + D+ K
Sbjct: 128 SGEQDIIQLRPSHTRFYDLYITYSTSYRVPKMYLVGFNNDGTPLTPQQMFQDIAPDYRTK 187
Query: 361 TVTMEVHPHLPGGVLMASVHPCRQAEVMKKLIEAVA------------------------ 468
T T+E P V+ S+HPCR A VM+ L+E V
Sbjct: 188 TATIEKLPFFKSAVVAVSIHPCRHANVMRVLMEKVRAAKQKPVEEEQPDGpreDWEDLQD 247
Query: 469 EGGAVLGVHQYIVIFLKFVQAVIPTIEYDYT 561
E + L V QY+V+FLKF+ +V P IE+DYT
Sbjct: 248 EVDSSLRVVQYLVVFLKFITSVTPGIEHDYT 278
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,207,353
Number of Sequences: 369166
Number of extensions: 1112001
Number of successful extensions: 2630
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2547
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2617
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5560129980
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)