Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00716 (865 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P15178|SYD_RAT Aspartyl-tRNA synthetase (Aspartate--tRNA... 333 4e-91 sp|Q922B2|SYD_MOUSE Aspartyl-tRNA synthetase (Aspartate--tR... 333 5e-91 sp|P14868|SYD_HUMAN Aspartyl-tRNA synthetase (Aspartate--tR... 332 1e-90 sp|Q03577|SYD_CAEEL Aspartyl-tRNA synthetase (Aspartate--tR... 320 3e-87 sp|P04802|SYDC_YEAST Aspartyl-tRNA synthetase, cytoplasmic ... 298 2e-80 sp|Q979P6|SYD_THEVO Aspartyl-tRNA synthetase (Aspartate--tR... 177 3e-44 sp|Q8TQ68|SYD_METAC Aspartyl-tRNA synthetase (Aspartate--tR... 172 8e-43 sp|Q58950|SYD_METJA Aspartyl-tRNA synthetase (Aspartate--tR... 168 2e-41 sp|Q8Q0R2|SYD_METMA Aspartyl-tRNA synthetase (Aspartate--tR... 167 3e-41 sp|Q8TXG4|SYD_METKA Aspartyl-tRNA synthetase (Aspartate--tR... 166 6e-41
>sp|P15178|SYD_RAT Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 501 Score = 333 bits (854), Expect = 4e-91 Identities = 162/254 (63%), Positives = 188/254 (74%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQLY QMCI EKVF IGPVFRAE+SNTHRHLTEF GLD+EM FN HYHEV+ I Sbjct: 248 QSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIA 307 Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361 +TLV IFK L+ F EI V KQF EPF++LEPTL L + E +AML EAG+EM + ED Sbjct: 308 DTLVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMDDEED 367 Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541 LST NE TDFYVLDK+PL+VRPFYTMPD P SNSYD+FMRGEEI+S Sbjct: 368 LSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILS 427 Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721 GAQR+HD L E A+ H I+L+ IK Y++SF +G PHAGGGIGL+RV ML+LGL N+R Sbjct: 428 GAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVR 487 Query: 722 RVSMFPRDPNRYRP 763 + SMFPRDP R P Sbjct: 488 QTSMFPRDPKRLTP 501
>sp|Q922B2|SYD_MOUSE Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 501 Score = 333 bits (853), Expect = 5e-91 Identities = 162/254 (63%), Positives = 188/254 (74%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQLY QMCI EKVF IGPVFRAE+SNTHRHLTEF GLD+EM FN HYHEV+ I Sbjct: 248 QSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIA 307 Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361 +TLV IFK L+ F EI V KQF EPF++LEPTL L + E +AML EAG+EM + ED Sbjct: 308 DTLVQIFKGLQERFQTEIQTVSKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMDDEED 367 Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541 LST NE TDFYVLDK+PL+VRPFYTMPD P SNSYD+FMRGEEI+S Sbjct: 368 LSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILS 427 Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721 GAQR+HD L E A+ H I+L+ IK Y++SF +G PHAGGGIGL+RV ML+LGL N+R Sbjct: 428 GAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVR 487 Query: 722 RVSMFPRDPNRYRP 763 + SMFPRDP R P Sbjct: 488 QTSMFPRDPKRLTP 501
>sp|P14868|SYD_HUMAN Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 501 Score = 332 bits (850), Expect = 1e-90 Identities = 159/254 (62%), Positives = 189/254 (74%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQLY QMCI EKVF+IGPVFRAE+SNTHRHLTEF GLD+EM FN HYHEV+ I Sbjct: 248 QSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIA 307 Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361 +T+V IFK L+ F EI V KQF EPF++LEPTL L + E +AML EAG+EM + +D Sbjct: 308 DTMVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMGDEDD 367 Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541 LST NE TDFY+LDK+PL+VRPFYTMPD P SNSYD+FMRGEEI+S Sbjct: 368 LSTPNEKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILS 427 Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721 GAQR+HD L E A+ H I+L+ IK Y++SF +G PHAGGGIGL+RV ML+LGL N+R Sbjct: 428 GAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVR 487 Query: 722 RVSMFPRDPNRYRP 763 + SMFPRDP R P Sbjct: 488 QTSMFPRDPKRLTP 501
>sp|Q03577|SYD_CAEEL Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 531 Score = 320 bits (820), Expect = 3e-87 Identities = 153/254 (60%), Positives = 186/254 (73%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQLY QM I G EKV+ IGPVFRAE+SNTHRH+TEF GLD+EM FN HYHEV+ TI Sbjct: 278 QSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDLEMAFNFHYHEVMETIA 337 Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361 E L +FK L+ N+ EIA V Q+ +EPF++ EP LIL + + + +L E GIE+ + +D Sbjct: 338 EVLTQMFKGLQQNYQDEIAAVGNQYPAEPFQFCEPPLILKYPDAITLLRENGIEIGDEDD 397 Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541 LST E TDFYVLDKFPLSVRPFYTMPD +SNSYD+FMRGEEI+S Sbjct: 398 LSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHDERYSNSYDMFMRGEEILS 457 Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721 GAQR+HDA L E A H+++L I+ Y++SF+YGC PHAGGGIGL+RV ML+LGL NIR Sbjct: 458 GAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAGGGIGLERVTMLFLGLHNIR 517 Query: 722 RVSMFPRDPNRYRP 763 S+FPRDP R P Sbjct: 518 LASLFPRDPKRLTP 531
>sp|P04802|SYDC_YEAST Aspartyl-tRNA synthetase, cytoplasmic (Aspartate--tRNA ligase) (AspRS) Length = 557 Score = 298 bits (762), Expect = 2e-80 Identities = 150/258 (58%), Positives = 178/258 (68%), Gaps = 4/258 (1%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQ Q IV E+V+ IGPVFRAENSNTHRH+TEFTGLDMEM F HYHEVL+T+ Sbjct: 300 QSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLS 359 Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLI--LTFAEGVAMLNEAGIEMSEH 355 E V IF +L F+ EI VRKQ+ E F+ + + LT+ EG+ ML AG E+ + Sbjct: 360 ELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGIEMLRAAGKEIGDF 419 Query: 356 EDLSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEI 535 EDLST NE TDFY+LDKFPL +RPFYTMPD P +SNSYD FMRGEEI Sbjct: 420 EDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEI 479 Query: 536 MSGAQRVHDAAKLRESAMKHRINLDT--IKDYLESFEYGCKPHAGGGIGLDRVVMLYLGL 709 +SGAQR+HD A L+E H ++ + +KDY + F YGC PHAGGGIGL+RVVM YL L Sbjct: 480 LSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDL 539 Query: 710 DNIRRVSMFPRDPNRYRP 763 NIRR S+FPRDP R RP Sbjct: 540 KNIRRASLFPRDPKRLRP 557
>sp|Q979P6|SYD_THEVO Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 428 Score = 177 bits (450), Expect = 3e-44 Identities = 100/257 (38%), Positives = 141/257 (54%), Gaps = 3/257 (1%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQLY ++ + G EKVF +GP FRAE NT RHL EFT +D+EM F +H N Sbjct: 185 QSPQLYKEILMSSGFEKVFEVGPAFRAEEHNTTRHLNEFTSIDIEMSFADH-----NDAM 239 Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLI---LTFAEGVAMLNEAGIEMSE 352 L + K N E K P + +T+ E + +L + G+E Sbjct: 240 RILENAVKSGIENMINENG---KDLQENGINISIPEIPFPRITYKECIKLLEKEGLEFQF 296 Query: 353 HEDLSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEE 532 D S DFY + ++P S+RPFYTMP+ D P +NS+D+ R E Sbjct: 297 GNDFSPEE-----LRIIGRNFKDFYFITEWPSSLRPFYTMPNRDDPTITNSFDLQYREVE 351 Query: 533 IMSGAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLD 712 + SGAQRVHD L + + ++N+D+ K Y+++F+YG PHAG G+GL+R+ M+ LGL+ Sbjct: 352 VTSGAQRVHDPDLLLKRFNEKKLNIDSFKFYIQAFKYGMPPHAGWGLGLERLTMIVLGLN 411 Query: 713 NIRRVSMFPRDPNRYRP 763 NIR ++FPRD R P Sbjct: 412 NIRETTLFPRDRTRIIP 428
>sp|Q8TQ68|SYD_METAC Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 444 Score = 172 bits (437), Expect = 8e-43 Identities = 99/257 (38%), Positives = 142/257 (55%), Gaps = 3/257 (1%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQL+ Q+ + GG ++VF IGP+FRAE +T RHL E T +D+E+ F +H+ +V+ + Sbjct: 195 QSPQLFKQILMGGGFDRVFEIGPIFRAEEHDTRRHLNEATSIDVEVSFADHF-DVMEILE 253 Query: 182 ETLVHIFKQLETNFSA--EIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIE-MSE 352 + HI+ ++ N A EI V + PF L LT+ E + ++N E M Sbjct: 254 NLVAHIYTRVIENCKASLEILGVELKVPKTPF------LKLTYDEVIEIVNSRCEEKMHW 307 Query: 353 HEDLSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEE 532 +DL T E Y + +P ++PFY MP ED P FS S+D+ R E Sbjct: 308 GDDLGTLGEHTVGNYVYETTGESHYFIIDWPTEIKPFYAMPYEDRPEFSKSFDMMHRTME 367 Query: 533 IMSGAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLD 712 + SGAQR+H + L+ +N D + YL++FEYG PHAG G+G +R VM LG + Sbjct: 368 LSSGAQRIHISELLKSRIESQGLNPDGFEFYLKAFEYGMPPHAGWGMGCERFVMTMLGTE 427 Query: 713 NIRRVSMFPRDPNRYRP 763 NIR +FPRD R P Sbjct: 428 NIRDTVLFPRDRRRLSP 444
>sp|Q58950|SYD_METJA Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 438 Score = 168 bits (425), Expect = 2e-41 Identities = 95/254 (37%), Positives = 138/254 (54%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQLY QM + G+++VF I P+FRAE NT RHL E T +D+EM F + + ++ + Sbjct: 195 QSPQLYKQMLMATGLDRVFEIAPIFRAEEHNTRRHLNEATSIDIEMAFADD-KDAMDILE 253 Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361 + + + F + N EI + +F+ P ++ +T+ E + + N G+E+S ED Sbjct: 254 KVVYNAFVDVYENRKKEIETLGIEFELPPEKFDR----ITYDEAIDIANAKGVEISWGED 309 Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541 LS E Y + +P +RPFYTMPDE P ++D+ + EI S Sbjct: 310 LSREAEKAIGEEMEG-----LYFITDWPSEIRPFYTMPDEKNPNICKAFDLMYKDLEISS 364 Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721 GAQR+H L E+ K +N D YLE+F+YG PHAG G+G DR M+ +NIR Sbjct: 365 GAQRIHLYDLLVENIKKKGLNPDGFTYYLEAFKYGMPPHAGWGLGADRFTMVLTQQENIR 424 Query: 722 RVSMFPRDPNRYRP 763 +FPRD R P Sbjct: 425 ECVLFPRDRQRLTP 438
>sp|Q8Q0R2|SYD_METMA Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 444 Score = 167 bits (424), Expect = 3e-41 Identities = 95/257 (36%), Positives = 142/257 (55%), Gaps = 3/257 (1%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQL+ Q+ + GG ++VF IGP+FRAE +T RHL E T +D+E+ F +H+ +V+ + Sbjct: 195 QSPQLFKQILMSGGFDRVFEIGPIFRAEEHDTRRHLNEATSIDVEVSFADHF-DVMELLE 253 Query: 182 ETLVHIFKQLETNF--SAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIE-MSE 352 + +++ ++ N S E+ V + PF L LT+ E + ++N E M Sbjct: 254 NLVAYVYTRVIENCKSSLEVLGVDLKVPKTPF------LKLTYDEVIEIINSRCEEKMHW 307 Query: 353 HEDLSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEE 532 +DL T E Y + +P ++PFY MP ED P FS S+D+ R E Sbjct: 308 GDDLGTLGEHTVGDHVYETTGESHYFIIDWPTEIKPFYAMPYEDRPEFSKSFDMMHRTME 367 Query: 533 IMSGAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLD 712 + SGAQR+H + L+ +N D + YL++FE+G PHAG G+G +R VM LG + Sbjct: 368 LSSGAQRIHIPSLLKNRIESQGLNPDGFEFYLKAFEFGMPPHAGWGMGCERFVMTMLGTE 427 Query: 713 NIRRVSMFPRDPNRYRP 763 NIR +FPRD R P Sbjct: 428 NIRDTVLFPRDRRRLSP 444
>sp|Q8TXG4|SYD_METKA Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS) Length = 431 Score = 166 bits (421), Expect = 6e-41 Identities = 93/254 (36%), Positives = 139/254 (54%) Frame = +2 Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181 QSPQLY QM + G E+V+ IGP+FRAE NT RHL E +D+EM F +V+ + Sbjct: 189 QSPQLYKQMLMAAGFERVYEIGPIFRAEEHNTRRHLNEAISVDIEMSFIESEEDVMRVLE 248 Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361 E L H+F+++ E+ + D E E P +T+ E + +L+E GIE+ ED Sbjct: 249 ELLAHVFRKVREECEKEL----EALDRELPELETPFERITYEETLDLLSEHGIEVEWGED 304 Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541 L T E + + + ++P RPFYTM +D + ++D+ +G E+ S Sbjct: 305 LPTEAE-----RKLGEIFEEPFFITEWpreTRPFYTMAKDD--EVTTAFDLMYQGLELAS 357 Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721 GAQR H L + ++ + + YLE+F+YG PH G G+GL+R +M G +NIR Sbjct: 358 GAQREHRYDVLVRQIEEQGLSPEDFRHYLEAFKYGMPPHGGWGLGLERTLMTITGAENIR 417 Query: 722 RVSMFPRDPNRYRP 763 V++FPRD R P Sbjct: 418 EVTLFPRDRKRLHP 431
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 106,996,264 Number of Sequences: 369166 Number of extensions: 2288021 Number of successful extensions: 6911 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6115 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6562 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8582957970 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)