Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_L14
(817 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P15178|SYD_RAT Aspartyl-tRNA synthetase (Aspartate--tRNA... 333 3e-91
sp|Q922B2|SYD_MOUSE Aspartyl-tRNA synthetase (Aspartate--tR... 333 4e-91
sp|P14868|SYD_HUMAN Aspartyl-tRNA synthetase (Aspartate--tR... 332 1e-90
sp|Q03577|SYD_CAEEL Aspartyl-tRNA synthetase (Aspartate--tR... 320 3e-87
sp|P04802|SYDC_YEAST Aspartyl-tRNA synthetase, cytoplasmic ... 298 2e-80
sp|Q979P6|SYD_THEVO Aspartyl-tRNA synthetase (Aspartate--tR... 177 2e-44
sp|Q8TQ68|SYD_METAC Aspartyl-tRNA synthetase (Aspartate--tR... 172 8e-43
sp|Q58950|SYD_METJA Aspartyl-tRNA synthetase (Aspartate--tR... 168 2e-41
sp|Q8Q0R2|SYD_METMA Aspartyl-tRNA synthetase (Aspartate--tR... 167 2e-41
sp|Q8TXG4|SYD_METKA Aspartyl-tRNA synthetase (Aspartate--tR... 166 5e-41
>sp|P15178|SYD_RAT Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 501
Score = 333 bits (854), Expect = 3e-91
Identities = 162/254 (63%), Positives = 188/254 (74%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQLY QMCI EKVF IGPVFRAE+SNTHRHLTEF GLD+EM FN HYHEV+ I
Sbjct: 248 QSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIA 307
Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361
+TLV IFK L+ F EI V KQF EPF++LEPTL L + E +AML EAG+EM + ED
Sbjct: 308 DTLVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMDDEED 367
Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541
LST NE TDFYVLDK+PL+VRPFYTMPD P SNSYD+FMRGEEI+S
Sbjct: 368 LSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILS 427
Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721
GAQR+HD L E A+ H I+L+ IK Y++SF +G PHAGGGIGL+RV ML+LGL N+R
Sbjct: 428 GAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVR 487
Query: 722 RVSMFPRDPNRYRP 763
+ SMFPRDP R P
Sbjct: 488 QTSMFPRDPKRLTP 501
>sp|Q922B2|SYD_MOUSE Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 501
Score = 333 bits (853), Expect = 4e-91
Identities = 162/254 (63%), Positives = 188/254 (74%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQLY QMCI EKVF IGPVFRAE+SNTHRHLTEF GLD+EM FN HYHEV+ I
Sbjct: 248 QSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIA 307
Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361
+TLV IFK L+ F EI V KQF EPF++LEPTL L + E +AML EAG+EM + ED
Sbjct: 308 DTLVQIFKGLQERFQTEIQTVSKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMDDEED 367
Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541
LST NE TDFYVLDK+PL+VRPFYTMPD P SNSYD+FMRGEEI+S
Sbjct: 368 LSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILS 427
Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721
GAQR+HD L E A+ H I+L+ IK Y++SF +G PHAGGGIGL+RV ML+LGL N+R
Sbjct: 428 GAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVR 487
Query: 722 RVSMFPRDPNRYRP 763
+ SMFPRDP R P
Sbjct: 488 QTSMFPRDPKRLTP 501
>sp|P14868|SYD_HUMAN Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 501
Score = 332 bits (850), Expect = 1e-90
Identities = 159/254 (62%), Positives = 189/254 (74%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQLY QMCI EKVF+IGPVFRAE+SNTHRHLTEF GLD+EM FN HYHEV+ I
Sbjct: 248 QSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIA 307
Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361
+T+V IFK L+ F EI V KQF EPF++LEPTL L + E +AML EAG+EM + +D
Sbjct: 308 DTMVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMGDEDD 367
Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541
LST NE TDFY+LDK+PL+VRPFYTMPD P SNSYD+FMRGEEI+S
Sbjct: 368 LSTPNEKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILS 427
Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721
GAQR+HD L E A+ H I+L+ IK Y++SF +G PHAGGGIGL+RV ML+LGL N+R
Sbjct: 428 GAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVR 487
Query: 722 RVSMFPRDPNRYRP 763
+ SMFPRDP R P
Sbjct: 488 QTSMFPRDPKRLTP 501
>sp|Q03577|SYD_CAEEL Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 531
Score = 320 bits (820), Expect = 3e-87
Identities = 153/254 (60%), Positives = 186/254 (73%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQLY QM I G EKV+ IGPVFRAE+SNTHRH+TEF GLD+EM FN HYHEV+ TI
Sbjct: 278 QSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDLEMAFNFHYHEVMETIA 337
Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361
E L +FK L+ N+ EIA V Q+ +EPF++ EP LIL + + + +L E GIE+ + +D
Sbjct: 338 EVLTQMFKGLQQNYQDEIAAVGNQYPAEPFQFCEPPLILKYPDAITLLRENGIEIGDEDD 397
Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541
LST E TDFYVLDKFPLSVRPFYTMPD +SNSYD+FMRGEEI+S
Sbjct: 398 LSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHDERYSNSYDMFMRGEEILS 457
Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721
GAQR+HDA L E A H+++L I+ Y++SF+YGC PHAGGGIGL+RV ML+LGL NIR
Sbjct: 458 GAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAGGGIGLERVTMLFLGLHNIR 517
Query: 722 RVSMFPRDPNRYRP 763
S+FPRDP R P
Sbjct: 518 LASLFPRDPKRLTP 531
>sp|P04802|SYDC_YEAST Aspartyl-tRNA synthetase, cytoplasmic (Aspartate--tRNA ligase)
(AspRS)
Length = 557
Score = 298 bits (762), Expect = 2e-80
Identities = 150/258 (58%), Positives = 178/258 (68%), Gaps = 4/258 (1%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQ Q IV E+V+ IGPVFRAENSNTHRH+TEFTGLDMEM F HYHEVL+T+
Sbjct: 300 QSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLS 359
Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLI--LTFAEGVAMLNEAGIEMSEH 355
E V IF +L F+ EI VRKQ+ E F+ + + LT+ EG+ ML AG E+ +
Sbjct: 360 ELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGIEMLRAAGKEIGDF 419
Query: 356 EDLSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEI 535
EDLST NE TDFY+LDKFPL +RPFYTMPD P +SNSYD FMRGEEI
Sbjct: 420 EDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEI 479
Query: 536 MSGAQRVHDAAKLRESAMKHRINLDT--IKDYLESFEYGCKPHAGGGIGLDRVVMLYLGL 709
+SGAQR+HD A L+E H ++ + +KDY + F YGC PHAGGGIGL+RVVM YL L
Sbjct: 480 LSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDL 539
Query: 710 DNIRRVSMFPRDPNRYRP 763
NIRR S+FPRDP R RP
Sbjct: 540 KNIRRASLFPRDPKRLRP 557
>sp|Q979P6|SYD_THEVO Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 428
Score = 177 bits (450), Expect = 2e-44
Identities = 100/257 (38%), Positives = 141/257 (54%), Gaps = 3/257 (1%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQLY ++ + G EKVF +GP FRAE NT RHL EFT +D+EM F +H N
Sbjct: 185 QSPQLYKEILMSSGFEKVFEVGPAFRAEEHNTTRHLNEFTSIDIEMSFADH-----NDAM 239
Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLI---LTFAEGVAMLNEAGIEMSE 352
L + K N E K P + +T+ E + +L + G+E
Sbjct: 240 RILENAVKSGIENMINENG---KDLQENGINISIPEIPFPRITYKECIKLLEKEGLEFQF 296
Query: 353 HEDLSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEE 532
D S DFY + ++P S+RPFYTMP+ D P +NS+D+ R E
Sbjct: 297 GNDFSPEE-----LRIIGRNFKDFYFITEWPSSLRPFYTMPNRDDPTITNSFDLQYREVE 351
Query: 533 IMSGAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLD 712
+ SGAQRVHD L + + ++N+D+ K Y+++F+YG PHAG G+GL+R+ M+ LGL+
Sbjct: 352 VTSGAQRVHDPDLLLKRFNEKKLNIDSFKFYIQAFKYGMPPHAGWGLGLERLTMIVLGLN 411
Query: 713 NIRRVSMFPRDPNRYRP 763
NIR ++FPRD R P
Sbjct: 412 NIRETTLFPRDRTRIIP 428
>sp|Q8TQ68|SYD_METAC Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 444
Score = 172 bits (437), Expect = 8e-43
Identities = 99/257 (38%), Positives = 142/257 (55%), Gaps = 3/257 (1%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQL+ Q+ + GG ++VF IGP+FRAE +T RHL E T +D+E+ F +H+ +V+ +
Sbjct: 195 QSPQLFKQILMGGGFDRVFEIGPIFRAEEHDTRRHLNEATSIDVEVSFADHF-DVMEILE 253
Query: 182 ETLVHIFKQLETNFSA--EIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIE-MSE 352
+ HI+ ++ N A EI V + PF L LT+ E + ++N E M
Sbjct: 254 NLVAHIYTRVIENCKASLEILGVELKVPKTPF------LKLTYDEVIEIVNSRCEEKMHW 307
Query: 353 HEDLSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEE 532
+DL T E Y + +P ++PFY MP ED P FS S+D+ R E
Sbjct: 308 GDDLGTLGEHTVGNYVYETTGESHYFIIDWPTEIKPFYAMPYEDRPEFSKSFDMMHRTME 367
Query: 533 IMSGAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLD 712
+ SGAQR+H + L+ +N D + YL++FEYG PHAG G+G +R VM LG +
Sbjct: 368 LSSGAQRIHISELLKSRIESQGLNPDGFEFYLKAFEYGMPPHAGWGMGCERFVMTMLGTE 427
Query: 713 NIRRVSMFPRDPNRYRP 763
NIR +FPRD R P
Sbjct: 428 NIRDTVLFPRDRRRLSP 444
>sp|Q58950|SYD_METJA Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 438
Score = 168 bits (425), Expect = 2e-41
Identities = 95/254 (37%), Positives = 138/254 (54%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQLY QM + G+++VF I P+FRAE NT RHL E T +D+EM F + + ++ +
Sbjct: 195 QSPQLYKQMLMATGLDRVFEIAPIFRAEEHNTRRHLNEATSIDIEMAFADD-KDAMDILE 253
Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361
+ + + F + N EI + +F+ P ++ +T+ E + + N G+E+S ED
Sbjct: 254 KVVYNAFVDVYENRKKEIETLGIEFELPPEKFDR----ITYDEAIDIANAKGVEISWGED 309
Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541
LS E Y + +P +RPFYTMPDE P ++D+ + EI S
Sbjct: 310 LSREAEKAIGEEMEG-----LYFITDWPSEIRPFYTMPDEKNPNICKAFDLMYKDLEISS 364
Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721
GAQR+H L E+ K +N D YLE+F+YG PHAG G+G DR M+ +NIR
Sbjct: 365 GAQRIHLYDLLVENIKKKGLNPDGFTYYLEAFKYGMPPHAGWGLGADRFTMVLTQQENIR 424
Query: 722 RVSMFPRDPNRYRP 763
+FPRD R P
Sbjct: 425 ECVLFPRDRQRLTP 438
>sp|Q8Q0R2|SYD_METMA Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 444
Score = 167 bits (424), Expect = 2e-41
Identities = 95/257 (36%), Positives = 142/257 (55%), Gaps = 3/257 (1%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQL+ Q+ + GG ++VF IGP+FRAE +T RHL E T +D+E+ F +H+ +V+ +
Sbjct: 195 QSPQLFKQILMSGGFDRVFEIGPIFRAEEHDTRRHLNEATSIDVEVSFADHF-DVMELLE 253
Query: 182 ETLVHIFKQLETNF--SAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIE-MSE 352
+ +++ ++ N S E+ V + PF L LT+ E + ++N E M
Sbjct: 254 NLVAYVYTRVIENCKSSLEVLGVDLKVPKTPF------LKLTYDEVIEIINSRCEEKMHW 307
Query: 353 HEDLSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEE 532
+DL T E Y + +P ++PFY MP ED P FS S+D+ R E
Sbjct: 308 GDDLGTLGEHTVGDHVYETTGESHYFIIDWPTEIKPFYAMPYEDRPEFSKSFDMMHRTME 367
Query: 533 IMSGAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLD 712
+ SGAQR+H + L+ +N D + YL++FE+G PHAG G+G +R VM LG +
Sbjct: 368 LSSGAQRIHIPSLLKNRIESQGLNPDGFEFYLKAFEFGMPPHAGWGMGCERFVMTMLGTE 427
Query: 713 NIRRVSMFPRDPNRYRP 763
NIR +FPRD R P
Sbjct: 428 NIRDTVLFPRDRRRLSP 444
>sp|Q8TXG4|SYD_METKA Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS)
Length = 431
Score = 166 bits (421), Expect = 5e-41
Identities = 93/254 (36%), Positives = 139/254 (54%)
Frame = +2
Query: 2 QSPQLYNQMCIVGGMEKVFAIGPVFRAENSNTHRHLTEFTGLDMEMQFNNHYHEVLNTIC 181
QSPQLY QM + G E+V+ IGP+FRAE NT RHL E +D+EM F +V+ +
Sbjct: 189 QSPQLYKQMLMAAGFERVYEIGPIFRAEEHNTRRHLNEAISVDIEMSFIESEEDVMRVLE 248
Query: 182 ETLVHIFKQLETNFSAEIACVRKQFDSEPFEYLEPTLILTFAEGVAMLNEAGIEMSEHED 361
E L H+F+++ E+ + D E E P +T+ E + +L+E GIE+ ED
Sbjct: 249 ELLAHVFRKVREECEKEL----EALDRELPELETPFERITYEETLDLLSEHGIEVEWGED 304
Query: 362 LSTTNEXXXXXXXXXXXXTDFYVLDKFPLSVRPFYTMPDEDYPGFSNSYDVFMRGEEIMS 541
L T E + + + ++P RPFYTM +D + ++D+ +G E+ S
Sbjct: 305 LPTEAE-----RKLGEIFEEPFFITEWpreTRPFYTMAKDD--EVTTAFDLMYQGLELAS 357
Query: 542 GAQRVHDAAKLRESAMKHRINLDTIKDYLESFEYGCKPHAGGGIGLDRVVMLYLGLDNIR 721
GAQR H L + ++ + + YLE+F+YG PH G G+GL+R +M G +NIR
Sbjct: 358 GAQREHRYDVLVRQIEEQGLSPEDFRHYLEAFKYGMPPHGGWGLGLERTLMTITGAENIR 417
Query: 722 RVSMFPRDPNRYRP 763
V++FPRD R P
Sbjct: 418 EVTLFPRDRKRLHP 431
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,600,391
Number of Sequences: 369166
Number of extensions: 2200993
Number of successful extensions: 6818
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6022
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6469
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7811456130
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)