DrC_00665
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00665 (861 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O95433|AHSA1_HUMAN Activator of 90 kDa heat shock protei... 173 6e-43 sp|Q8BK64|AHSA1_MOUSE Activator of 90 kDa heat shock protei... 172 1e-42 sp|Q12449|AHA1_YEAST Hsp90 co-chaperone AHA1 (Activator of ... 88 3e-17 sp|Q9P782|YNY8_SCHPO Hypothetical protein C1711.08 in chrom... 76 1e-13 sp|P53834|HCH1_YEAST Hsp90 co-chaperone HCH1 (High-copy Hsp... 63 9e-10 sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP-E protein) 33 0.78 sp|Q98QL0|RNR_MYCPU Ribonuclease R (RNase R) (VacB protein ... 33 0.78 sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170... 33 0.78 sp|Q97T80|ZMPC_STRPN Zinc metalloprotease zmpC precursor (M... 33 1.3 sp|P36251|RPOB_LIBAS DNA-directed RNA polymerase beta chain... 33 1.3
>sp|O95433|AHSA1_HUMAN Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38) Length = 338 Score = 173 bits (438), Expect = 6e-43 Identities = 91/230 (39%), Positives = 137/230 (59%), Gaps = 5/230 (2%) Frame = +3 Query: 63 EGDPRWIVEEREDAKNVNNWHWSEKNATQWSKDMFKKLLVGLVIDNNEYFFEITDLSKIE 242 EGDPRWIVEER DA NVNNWHW+E++A+ WS D K L + + + N E E+T++SK++ Sbjct: 6 EGDPRWIVEERADATNVNNWHWTERDASNWSTDKLKTLFLAVQVQNEEGKCEVTEVSKLD 65 Query: 243 GEAIANNRKAKVIVFYEWVIEAEWKGHLKNNINKTEFKGKFDIPNLSEEFDSSEIDVNVS 422 GEA NNRK K+I FYEW ++ W G K+ + ++KG +IPNLS+E E++++VS Sbjct: 66 GEASINNRKGKLIFFYEWSVKLNWTGTSKSGV---QYKGHVEIPNLSDENSVDEVEISVS 122 Query: 423 VESHSNDANQMKDYIRLECSKVIREKLGKYISDLKTEYSKDLILPTKKVSNDGPVVVSNA 602 + D N + ++ E K++RE +G YIS LKTE+++ +ILPT + P V A Sbjct: 123 LAKDEPDTN-LVALMKEEGVKLLREAMGIYISTLKTEFTQGMILPTMNGESVDP-VGQPA 180 Query: 603 YKQTMNEIVVSKSHKNS-----SLTFLSLELNEEFFCTPSDLYQVFINSD 737 K + + S + + + L E F +P +LY+VF + Sbjct: 181 LKTEERKAKPAPSKTQARPVGVKIPTCKITLKETFLTSPEELYRVFTTQE 230
>sp|Q8BK64|AHSA1_MOUSE Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) Length = 338 Score = 172 bits (436), Expect = 1e-42 Identities = 90/229 (39%), Positives = 138/229 (60%), Gaps = 4/229 (1%) Frame = +3 Query: 63 EGDPRWIVEEREDAKNVNNWHWSEKNATQWSKDMFKKLLVGLVIDNNEYFFEITDLSKIE 242 EGDPRWIVEER DA NVNNWHW+E++A+ WS + K L + + ++N E E+T+++K++ Sbjct: 6 EGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGKCEVTEVNKLD 65 Query: 243 GEAIANNRKAKVIVFYEWVIEAEWKGHLKNNINKTEFKGKFDIPNLSEEFDSSEIDVNVS 422 GEA NNRK K+I FYEW I+ W G K+ + ++KG +IPNLS+E E++++VS Sbjct: 66 GEASINNRKGKLIFFYEWTIKLNWTGTSKSGV---QYKGHVEIPNLSDENSVDEVEISVS 122 Query: 423 VESHSNDANQMKDYIRLECSKVIREKLGKYISDLKTEYSKDLILPTKKVSNDGPVVVSNA 602 + D N + ++ + K++RE +G YIS LKTE+++ +ILPT + PV Sbjct: 123 LAKDEPDTN-LVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPAL 181 Query: 603 YKQTMN-EIVVSKSHKNS---SLTFLSLELNEEFFCTPSDLYQVFINSD 737 +T + SKS + + L E F +P +LY+VF + Sbjct: 182 KTETCKAKSAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQE 230
>sp|Q12449|AHA1_YEAST Hsp90 co-chaperone AHA1 (Activator of Hsp90 ATPase protein 1) Length = 350 Score = 87.8 bits (216), Expect = 3e-17 Identities = 58/231 (25%), Positives = 110/231 (47%), Gaps = 23/231 (9%) Frame = +3 Query: 108 NVNNWHWSEKNATQWSKDMFKKLLVGLVIDN--NEYFFEITDLSKIEGEAIANNRKAKVI 281 N NNWHW +KN W+K+ FK+ LVG+ + ++ + +I +S IEG+ N RK KVI Sbjct: 5 NPNNWHWVDKNCIGWAKEYFKQKLVGVEAGSVKDKKYAKIKSVSSIEGDCEVNQRKGKVI 64 Query: 282 VFYEWVIEAEWKGHLKNNINKT-EFKGKFDIPNLSEEFDSSEIDVNVSVESHSNDANQMK 458 ++ I +GH+ + F+G ++P ++ + ++S ++S+ +++ ++ K Sbjct: 65 SLFDLKITVLIEGHVDSKDGSALPFEGSINVPEVAFDSEASSYQFDISIFKETSELSEAK 124 Query: 459 DYIRLECSKVIREKLGKYISDLKTEYSKDLILPTKKVSND---------GPVVVSNAYKQ 611 IR E +R+ ++ DL + D+ +P +V ++ + +A K Sbjct: 125 PLIRSELLPKLRQIFQQFGKDLLATHGNDIQVPESQVKSNYTRGNQKSSFTEIKDSASKP 184 Query: 612 TMNEIVVS-----------KSHKNSSLTFLSLELNEEFFCTPSDLYQVFIN 731 N + S K +N S S+ L F S+LY+ F++ Sbjct: 185 KKNALPSSTSTSAPVSSTNKVPQNGSGNSTSIYLEPTFNVPSSELYETFLD 235
>sp|Q9P782|YNY8_SCHPO Hypothetical protein C1711.08 in chromosome II Length = 336 Score = 76.3 bits (186), Expect = 1e-13 Identities = 45/170 (26%), Positives = 81/170 (47%), Gaps = 2/170 (1%) Frame = +3 Query: 108 NVNNWHWSEKNATQWSKDMFKKLLVGLVIDNNEYFFEITDLSKIEGEAIANNRKAKVIVF 287 N NNWHW+ K+ WS + F K L + IT ++ EG+ + RK KVI Sbjct: 7 NPNNWHWTSKDCRVWSHEYFNKELPKIQASEGPTSARITQVNSCEGDVDVSMRKRKVITI 66 Query: 288 YEWVIEAEWKGHLKNNINKTEFKGKFDIPNLSEEFDSSEIDVNVSVESHSNDANQMKDYI 467 ++ I+ E+KG K+ + T G P LS + S+ ++ + S S + +K+ + Sbjct: 67 FDLKIQMEFKGETKDGVEAT---GSITCPELSYDLGYSDYVFDIDIYSASKEKEPIKELV 123 Query: 468 RLECSKVIREKLGKYISDLKTEYSKDLILPTKKVSNDGP--VVVSNAYKQ 611 R + IR+ + L + D+ L T++ + + + V +++KQ Sbjct: 124 REKIIPQIRQLFSGFSQVLLQTHGDDVYLSTEEHNGNAARGLPVHSSFKQ 173
>sp|P53834|HCH1_YEAST Hsp90 co-chaperone HCH1 (High-copy Hsp90 suppressor protein 1) Length = 153 Score = 63.2 bits (152), Expect = 9e-10 Identities = 48/155 (30%), Positives = 71/155 (45%), Gaps = 8/155 (5%) Frame = +3 Query: 108 NVNNWHWSEKNATQWSKDMFKKLLVGL--VIDNNEYFFEITDLSKIEGEAIANNRKAKVI 281 N NNWHW +KN WSKD L L V + + E+T +S I G++ + RK K I Sbjct: 5 NPNNWHWVDKNTLPWSKDYLNGKLTSLSTVSSDGKSKIELTQVSSITGDSNVSQRKGKPI 64 Query: 282 VFYEWVIEAEWK-GHLKNNINKTE-----FKGKFDIPNLSEEFDSSEIDVNVSVESHSND 443 +++ + K +L N + + GK +IP EF E D+ + S Sbjct: 65 CYFDLQLSMNVKVTNLDTNKDDEDDDGILADGKLEIP----EFMHDESDIPIL----SQG 116 Query: 444 ANQMKDYIRLECSKVIREKLGKYISDLKTEYSKDL 548 + +R E + E L KY DL E+SKD+ Sbjct: 117 FDAFDGLVRSEFVPKVVETLLKYQDDLIKEHSKDI 151
>sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP-E protein) Length = 2663 Score = 33.5 bits (75), Expect = 0.78 Identities = 42/161 (26%), Positives = 63/161 (39%), Gaps = 12/161 (7%) Frame = +3 Query: 234 KIEGEAIANNRKAKVIVFYEWVIEAEWKGHLKNNINKTEFKGKFDIPNLSEEFDSSEIDV 413 K E + + +NRK EW+ LKN I K + I ++ F++ I + Sbjct: 2217 KTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDR----ICQVNNFFNNRIIAI 2272 Query: 414 -NVSVESHSNDANQMKDYIR-LECSKVIREKLGKYISDLKTEYSKDLILPTKKVSNDGPV 587 N S E A K++ + L+ K EKL K LKT + + N P Sbjct: 2273 MNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPH 2332 Query: 588 VVSNAYKQT----------MNEIVVSKSHKNSSLTFLSLEL 680 V S A + T ++E S HK S + + EL Sbjct: 2333 VTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKEL 2373
>sp|Q98QL0|RNR_MYCPU Ribonuclease R (RNase R) (VacB protein homolog) Length = 725 Score = 33.5 bits (75), Expect = 0.78 Identities = 50/213 (23%), Positives = 84/213 (39%), Gaps = 44/213 (20%) Frame = +3 Query: 144 TQWSKDMFKKLLVGLVIDNNE-YFFEITDLSKIEGEAIANNRKAKVI------------- 281 +Q SK +F L GL++ NN+ F ++ ++ KI+G +NR I Sbjct: 32 SQLSKALFSLLDQGLIVKNNDGNFIKVNEIKKIQGIFKQSNRNFAFIETADEQSYFVAKA 91 Query: 282 -------------VFYEWVIEAEWKGHLKNNINKT---EFKGKFDIPNLSEEFDSSE--- 404 + YE E + K + I K E G I N + F++ E Sbjct: 92 HFNGAINSFEVEAIVYESPFEKDKKYAVVKKILKNTHPEIIGFIKISNGIKYFNAFEESF 151 Query: 405 ------IDVNVSVESHSNDANQMKDYIRLECSKVIREKL----GKYISDLKTE-YSKDLI 551 +D N+ VE D I + K++ +K+ K +S LK+ Y D++ Sbjct: 152 RSYKFFVDQNIDVEE--------DDVILVVVEKIVDQKIYVNFVKKVSTLKSNFYQIDIV 203 Query: 552 LPTKKVSNDGPVVVSNAYKQTMNEIVVSKSHKN 650 L K D P V + + + V+ K ++N Sbjct: 204 LEKSKTIIDFPEDVLDE-SALIEDHVIEKDYQN 235
>sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170) (CLIP-170) Length = 1433 Score = 33.5 bits (75), Expect = 0.78 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 3/120 (2%) Frame = +3 Query: 336 INKTEFKGKFDIPNLSEEFDSSEIDV-NVSVESHSNDANQMKDYIRLECSKVIREKLGKY 512 + K +GK +I LSE+ ++E + N+ E SN +++ E + EK Sbjct: 769 LQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVSNLTKELQG---KEQKLLDLEKNLSA 825 Query: 513 ISDLKTEYSKDLILPTKKVSN--DGPVVVSNAYKQTMNEIVVSKSHKNSSLTFLSLELNE 686 ++ +K K+L L +K ++ DG A ++T+N++ + K +S EL + Sbjct: 826 VNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKL----NQKEEQFALMSSELEQ 881
>sp|Q97T80|ZMPC_STRPN Zinc metalloprotease zmpC precursor (MMP-9 protease) Length = 1856 Score = 32.7 bits (73), Expect = 1.3 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 3/127 (2%) Frame = +3 Query: 252 IANNRKAKVIVFYEWVIEAEWKGHLKNNINKT-EFKGKFDIPNLSEEFDSSEIDVNVSVE 428 I N K +VI ++ K HL N+ + E + + E+ EI SVE Sbjct: 548 IENPAKEQVISGLDYYTPYTVKTHLTYNLGENNEENTETSTQDFQLEYKKIEIKDIDSVE 607 Query: 429 SHSNDANQMKDYIRLECSKVIREKLGKYISDLKTEYSKDLILPTKKV--SNDGPVVVSNA 602 + + ++ + Y+ L + KY +K++ K++ LP K + + DG V+ A Sbjct: 608 LYGKENDRYRRYLSLSEAPT---DTAKYFVKVKSDRFKEMYLPVKSITENTDGTYKVTVA 664 Query: 603 YKQTMNE 623 Q + E Sbjct: 665 VDQLVEE 671
>sp|P36251|RPOB_LIBAS DNA-directed RNA polymerase beta chain (RNAP beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 178 Score = 32.7 bits (73), Expect = 1.3 Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 2/109 (1%) Frame = +3 Query: 345 TEFKGKFDIPNLSEEFDSSEIDVNVSVESHSNDANQMKDYIRLECSKVIREKLGKYISDL 524 T F G + +S EFD + DV+ + A +K +RL V K I D+ Sbjct: 66 TAFSGAAMLEFVSYEFDPPKFDVDDCLWRDLTYAVPLKITLRLIVFDVDEFTGAKSIKDI 125 Query: 525 KTE--YSKDLILPTKKVSNDGPVVVSNAYKQTMNEIVVSKSHKNSSLTF 665 K + Y DL L TK DG V+ + IVVS+ H++ + F Sbjct: 126 KEQSIYMGDLPLMTK----DGTFVIKGTQR-----IVVSQLHRSPGIHF 165
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,471,943
Number of Sequences: 369166
Number of extensions: 1559965
Number of successful extensions: 4321
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4187
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4313
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8534739105
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
