Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00657 (1373 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O75717|WDHD1_HUMAN WD repeat and HMG-box DNA binding pro... 50 2e-05 sp|P59328|WDHD1_MOUSE WD repeat and HMG-box DNA binding pro... 48 6e-05 sp|Q99KP6|PRP19_MOUSE PRP19/PSO4 homolog (Nuclear matrix pr... 48 8e-05 sp|Q9UMS4|PRP19_HUMAN PRP19/PSO4 homolog (Nuclear matrix pr... 48 8e-05 sp|P42841|YN57_YEAST Hypothetical 53.1 kDa Trp-Asp repeats ... 47 1e-04 sp|Q9JMJ4|PRP19_RAT PRP19/PSO4 homolog (Neuronal differenti... 47 1e-04 sp|Q09866|YAG1_SCHPO Hypothetical WD-repeat protein C12G12.... 45 6e-04 sp|Q8N3Y1|FBXW8_HUMAN F-box/WD-repeat protein 8 (F-box and ... 44 8e-04 sp|Q8C7V3|UTP15_MOUSE U3 small nucleolar RNA-associated pro... 44 0.001 sp|Q96DI7|WDR57_HUMAN WD-repeat protein 57 (Prp8-binding pr... 44 0.001
>sp|O75717|WDHD1_HUMAN WD repeat and HMG-box DNA binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1) Length = 1129 Score = 49.7 bits (117), Expect = 2e-05 Identities = 18/60 (30%), Positives = 37/60 (61%) Frame = +1 Query: 1102 LLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQLSNQ 1281 + AG+ + I+D+ + Q F+ HD+ + ++ DP + S++ DGS+++WQ+S+Q Sbjct: 109 IAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSVRVWQISDQ 168
>sp|P59328|WDHD1_MOUSE WD repeat and HMG-box DNA binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1) Length = 970 Score = 48.1 bits (113), Expect = 6e-05 Identities = 16/60 (26%), Positives = 36/60 (60%) Frame = +1 Query: 1102 LLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQLSNQ 1281 + AG+ + ++D+ N Q F+ HD+ + ++ DP + S++ DG++++W +S+Q Sbjct: 109 IAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDIFLASASCDGTVRVWNISDQ 168
>sp|Q99KP6|PRP19_MOUSE PRP19/PSO4 homolog (Nuclear matrix protein 200) (Nuclear matrix protein SNEV) Length = 504 Score = 47.8 bits (112), Expect = 8e-05 Identities = 57/228 (25%), Positives = 92/228 (40%), Gaps = 22/228 (9%) Frame = +1 Query: 748 NKFGMGDSEGNFSLFHFSYADNSRAQYFQTRCPH-KGVLDFCFINSSSLVATAGSSA--- 915 NK G ++ N +F D S Q T H K V F S LV +A A Sbjct: 235 NKILTGGADKNVVVF-----DKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIR 289 Query: 916 LHGLPSVNQLHAVGGGNFDTNSVNI-SMWDVLLPSGRNQVRNLSDPQLA----------I 1062 + +P+ + + V +++ + D LL S +Q SD Q Sbjct: 290 IWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETS 349 Query: 1063 GVVALCYVSRYELLL--AGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVS 1236 G C + L+ GT +I I D+++ F H IT+I YY + Sbjct: 350 GCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409 Query: 1237 SATDGSIKIWQLSNQELFETFRSE---PIKASVFSKGD--LAVKGLDI 1365 +A D S+K+W L + F+T + + +K+ +F + LA+ G D+ Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDV 457
>sp|Q9UMS4|PRP19_HUMAN PRP19/PSO4 homolog (Nuclear matrix protein 200) (hPso4) Length = 504 Score = 47.8 bits (112), Expect = 8e-05 Identities = 57/228 (25%), Positives = 92/228 (40%), Gaps = 22/228 (9%) Frame = +1 Query: 748 NKFGMGDSEGNFSLFHFSYADNSRAQYFQTRCPH-KGVLDFCFINSSSLVATAGSSA--- 915 NK G ++ N +F D S Q T H K V F S LV +A A Sbjct: 235 NKILTGGADKNVVVF-----DKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIR 289 Query: 916 LHGLPSVNQLHAVGGGNFDTNSVNI-SMWDVLLPSGRNQVRNLSDPQLA----------I 1062 + +P+ + + V +++ + D LL S +Q SD Q Sbjct: 290 IWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETS 349 Query: 1063 GVVALCYVSRYELLL--AGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVS 1236 G C + L+ GT +I I D+++ F H IT+I YY + Sbjct: 350 GCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409 Query: 1237 SATDGSIKIWQLSNQELFETFRSE---PIKASVFSKGD--LAVKGLDI 1365 +A D S+K+W L + F+T + + +K+ +F + LA+ G D+ Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDV 457
>sp|P42841|YN57_YEAST Hypothetical 53.1 kDa Trp-Asp repeats containing protein in HXT14-PHA2 intergenic region Length = 465 Score = 47.0 bits (110), Expect = 1e-04 Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 12/126 (9%) Frame = +1 Query: 1000 DVLLPS---GRNQVRNL-------SDPQLAIGVVALCYVSRYELLLAGTRKGEIAIIDIR 1149 D++ P+ GR++V NL S ++ + A+ + L+ T GE ++ + Sbjct: 64 DIMPPNAYRGRDRVINLPSKFTHLSSNKVKHVIPAIQWTPEGRRLVVATYSGEFSLWNAS 123 Query: 1150 QNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQ--LSNQELFETFRSEPIKAS 1323 + + QAHDS +T +K + +S DG IKIWQ S + + +E I+ Sbjct: 124 SFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDM 183 Query: 1324 VFSKGD 1341 FS D Sbjct: 184 AFSSND 189
Score = 37.7 bits (86), Expect = 0.079 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Frame = +1 Query: 1123 GEIAIIDIRQN---KIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIW 1266 G + D+ QN I I AHD CIT++ +P+ + F ++A D +I+ W Sbjct: 327 GSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFW 377
>sp|Q9JMJ4|PRP19_RAT PRP19/PSO4 homolog (Neuronal differentiation-related gene protein) Length = 504 Score = 47.0 bits (110), Expect = 1e-04 Identities = 57/228 (25%), Positives = 91/228 (39%), Gaps = 22/228 (9%) Frame = +1 Query: 748 NKFGMGDSEGNFSLFHFSYADNSRAQYFQTRCPH-KGVLDFCFINSSSLVATAGSSA--- 915 NK G ++ N +F D S Q T H K V F S LV +A A Sbjct: 235 NKILTGGADKNVVVF-----DKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIR 289 Query: 916 LHGLPSVNQLHAVGGGNFDTNSVNI-SMWDVLLPSGRNQVRNLSDPQLA----------I 1062 + +P+ + + V +++ + D LL S +Q SD Q Sbjct: 290 IWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETS 349 Query: 1063 GVVALCYVSRYELLL--AGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVS 1236 G C + L+ GT I I D+++ F H IT+I YY + Sbjct: 350 GCSLTCAQFHPDGLIFGTGTMDSHIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409 Query: 1237 SATDGSIKIWQLSNQELFETFRSE---PIKASVFSKGD--LAVKGLDI 1365 +A D S+K+W L + F+T + + +K+ +F + LA+ G D+ Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDV 457
>sp|Q09866|YAG1_SCHPO Hypothetical WD-repeat protein C12G12.01c in chromosome I Length = 905 Score = 44.7 bits (104), Expect = 6e-04 Identities = 42/180 (23%), Positives = 69/180 (38%), Gaps = 1/180 (0%) Frame = +1 Query: 730 NFDANGNKFGMGDSEGNFSLFHFSYADNSRAQYFQTRCPHKGVLDFCFINSSSLVATAGS 909 +F N G G S GN SL + + FQ ++V + Sbjct: 52 SFHGNNEILGAGSSTGNISLLSVKHPE------FQ-----------------AVVTPGYA 88 Query: 910 SALHGLPSVNQLHAVGGGNFDTNSVNISMWDVLLPSGRNQVRNLSDPQLAIGVVALCYVS 1089 + L H V G N ++ +WD+ + L GV ++CY Sbjct: 89 RPCNSLAFSETEHLVAGFAKSRNESSLKLWDLNSLLSDPKSSPLMQSSTLDGVSSVCYKK 148 Query: 1090 RYELLLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQ-YYFVSSATDGSIKIW 1266 LLL G+ + IID RQ ++ ++ + + I +DP YF +++ DG I I+ Sbjct: 149 DTPLLLTGSTSRSVHIIDTRQ-QLDSVSSVNTQYYSNIVVDPFSPNYFAANSYDGDIAIF 207
>sp|Q8N3Y1|FBXW8_HUMAN F-box/WD-repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29) Length = 598 Score = 44.3 bits (103), Expect = 8e-04 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Frame = +1 Query: 1099 LLLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQL-S 1275 L+++G G + I D+R I AH ++A+++D + VS +G + +W Sbjct: 447 LMVSGNMDGRVRIHDLRSGNIALSLSAHQLRVSAVQMD--DWKIVSGGEEGLVSVWDYRM 504 Query: 1276 NQELFETFRSEPIKASVFSKGDL 1344 NQ+L+E + P++ FS L Sbjct: 505 NQKLWEVYSGHPVQHISFSSHSL 527
>sp|Q8C7V3|UTP15_MOUSE U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW) Length = 528 Score = 43.9 bits (102), Expect = 0.001 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Frame = +1 Query: 1096 ELLLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQLS 1275 +LL+AG+ G + + DI F+ H + + Y+ VS A D ++K+W + Sbjct: 93 QLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVDFTADNYHVVSGADDYTVKLWDIP 152 Query: 1276 NQELFETFR--SEPIKASVFSK--GDLAVKG 1356 N + TF+ S+ ++ SK DL V G Sbjct: 153 NSKEILTFKEHSDYVRCGCASKLNPDLFVTG 183
>sp|Q96DI7|WDR57_HUMAN WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 43.5 bits (101), Expect = 0.001 Identities = 20/95 (21%), Positives = 46/95 (48%) Frame = +1 Query: 988 ISMWDVLLPSGRNQVRNLSDPQLAIGVVALCYVSRYELLLAGTRKGEIAIIDIRQNKIQN 1167 + +WD+ + +N V+A+ + + +++G +I + D+RQNK+ Sbjct: 176 VKLWDIRKKAAIQTFQNTYQ------VLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTY 229 Query: 1168 IFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQL 1272 + H +T + L Y +S+A D ++++W + Sbjct: 230 TMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 34.3 bits (77), Expect = 0.87 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 2/77 (2%) Frame = +1 Query: 1078 CYVSRY--ELLLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDG 1251 CY +R +L+ G+ G + + DIR+ FQ + + A+ + +S D Sbjct: 157 CYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDN 215 Query: 1252 SIKIWQLSNQELFETFR 1302 IK+W L +L T R Sbjct: 216 DIKVWDLRQNKLTYTMR 232
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 137,982,461 Number of Sequences: 369166 Number of extensions: 2698504 Number of successful extensions: 8040 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 7130 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7995 length of database: 68,354,980 effective HSP length: 114 effective length of database: 47,295,190 effective search space used: 16222250170 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)