Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_C01
(785 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75717|WDHD1_HUMAN WD repeat and HMG-box DNA binding pro... 50 9e-06
sp|P59328|WDHD1_MOUSE WD repeat and HMG-box DNA binding pro... 48 3e-05
sp|Q99KP6|PRP19_MOUSE PRP19/PSO4 homolog (Nuclear matrix pr... 48 3e-05
sp|Q9UMS4|PRP19_HUMAN PRP19/PSO4 homolog (Nuclear matrix pr... 48 3e-05
sp|P42841|YN57_YEAST Hypothetical 53.1 kDa Trp-Asp repeats ... 47 6e-05
sp|Q9JMJ4|PRP19_RAT PRP19/PSO4 homolog (Neuronal differenti... 47 6e-05
sp|Q09866|YAG1_SCHPO Hypothetical WD-repeat protein C12G12.... 45 3e-04
sp|Q8N3Y1|FBXW8_HUMAN F-box/WD-repeat protein 8 (F-box and ... 44 4e-04
sp|Q8C7V3|UTP15_MOUSE U3 small nucleolar RNA-associated pro... 44 5e-04
sp|Q96DI7|WDR57_HUMAN WD-repeat protein 57 (Prp8-binding pr... 44 7e-04
>sp|O75717|WDHD1_HUMAN WD repeat and HMG-box DNA binding protein 1 (Acidic nucleoplasmic
DNA-binding protein 1) (And-1)
Length = 1129
Score = 49.7 bits (117), Expect = 9e-06
Identities = 18/60 (30%), Positives = 37/60 (61%)
Frame = +1
Query: 514 LLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQLSNQ 693
+ AG+ + I+D+ + Q F+ HD+ + ++ DP + S++ DGS+++WQ+S+Q
Sbjct: 109 IAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSVRVWQISDQ 168
>sp|P59328|WDHD1_MOUSE WD repeat and HMG-box DNA binding protein 1 (Acidic nucleoplasmic
DNA-binding protein 1) (And-1)
Length = 970
Score = 48.1 bits (113), Expect = 3e-05
Identities = 16/60 (26%), Positives = 36/60 (60%)
Frame = +1
Query: 514 LLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQLSNQ 693
+ AG+ + ++D+ N Q F+ HD+ + ++ DP + S++ DG++++W +S+Q
Sbjct: 109 IAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDIFLASASCDGTVRVWNISDQ 168
>sp|Q99KP6|PRP19_MOUSE PRP19/PSO4 homolog (Nuclear matrix protein 200) (Nuclear matrix
protein SNEV)
Length = 504
Score = 47.8 bits (112), Expect = 3e-05
Identities = 57/228 (25%), Positives = 92/228 (40%), Gaps = 22/228 (9%)
Frame = +1
Query: 160 NKFGMGDSEGNFSLFHFSYADNSRAQYFQTRCPH-KGVLDFCFINSSSLVATAGSSA--- 327
NK G ++ N +F D S Q T H K V F S LV +A A
Sbjct: 235 NKILTGGADKNVVVF-----DKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIR 289
Query: 328 LHGLPSVNQLHAVGGGNFDTNSVNI-SMWDVLLPSGRNQVRNLSDPQLA----------I 474
+ +P+ + + V +++ + D LL S +Q SD Q
Sbjct: 290 IWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETS 349
Query: 475 GVVALCYVSRYELLL--AGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVS 648
G C + L+ GT +I I D+++ F H IT+I YY +
Sbjct: 350 GCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409
Query: 649 SATDGSIKIWQLSNQELFETFRSE---PIKASVFSKGD--LAVKGLDI 777
+A D S+K+W L + F+T + + +K+ +F + LA+ G D+
Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDV 457
>sp|Q9UMS4|PRP19_HUMAN PRP19/PSO4 homolog (Nuclear matrix protein 200) (hPso4)
Length = 504
Score = 47.8 bits (112), Expect = 3e-05
Identities = 57/228 (25%), Positives = 92/228 (40%), Gaps = 22/228 (9%)
Frame = +1
Query: 160 NKFGMGDSEGNFSLFHFSYADNSRAQYFQTRCPH-KGVLDFCFINSSSLVATAGSSA--- 327
NK G ++ N +F D S Q T H K V F S LV +A A
Sbjct: 235 NKILTGGADKNVVVF-----DKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIR 289
Query: 328 LHGLPSVNQLHAVGGGNFDTNSVNI-SMWDVLLPSGRNQVRNLSDPQLA----------I 474
+ +P+ + + V +++ + D LL S +Q SD Q
Sbjct: 290 IWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETS 349
Query: 475 GVVALCYVSRYELLL--AGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVS 648
G C + L+ GT +I I D+++ F H IT+I YY +
Sbjct: 350 GCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409
Query: 649 SATDGSIKIWQLSNQELFETFRSE---PIKASVFSKGD--LAVKGLDI 777
+A D S+K+W L + F+T + + +K+ +F + LA+ G D+
Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDV 457
>sp|P42841|YN57_YEAST Hypothetical 53.1 kDa Trp-Asp repeats containing protein in
HXT14-PHA2 intergenic region
Length = 465
Score = 47.0 bits (110), Expect = 6e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 12/126 (9%)
Frame = +1
Query: 412 DVLLPS---GRNQVRNL-------SDPQLAIGVVALCYVSRYELLLAGTRKGEIAIIDIR 561
D++ P+ GR++V NL S ++ + A+ + L+ T GE ++ +
Sbjct: 64 DIMPPNAYRGRDRVINLPSKFTHLSSNKVKHVIPAIQWTPEGRRLVVATYSGEFSLWNAS 123
Query: 562 QNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQ--LSNQELFETFRSEPIKAS 735
+ + QAHDS +T +K + +S DG IKIWQ S + + +E I+
Sbjct: 124 SFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDM 183
Query: 736 VFSKGD 753
FS D
Sbjct: 184 AFSSND 189
Score = 37.7 bits (86), Expect = 0.036
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 3/51 (5%)
Frame = +1
Query: 535 GEIAIIDIRQN---KIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIW 678
G + D+ QN I I AHD CIT++ +P+ + F ++A D +I+ W
Sbjct: 327 GSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFW 377
>sp|Q9JMJ4|PRP19_RAT PRP19/PSO4 homolog (Neuronal differentiation-related gene protein)
Length = 504
Score = 47.0 bits (110), Expect = 6e-05
Identities = 57/228 (25%), Positives = 91/228 (39%), Gaps = 22/228 (9%)
Frame = +1
Query: 160 NKFGMGDSEGNFSLFHFSYADNSRAQYFQTRCPH-KGVLDFCFINSSSLVATAGSSA--- 327
NK G ++ N +F D S Q T H K V F S LV +A A
Sbjct: 235 NKILTGGADKNVVVF-----DKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIR 289
Query: 328 LHGLPSVNQLHAVGGGNFDTNSVNI-SMWDVLLPSGRNQVRNLSDPQLA----------I 474
+ +P+ + + V +++ + D LL S +Q SD Q
Sbjct: 290 IWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETS 349
Query: 475 GVVALCYVSRYELLL--AGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVS 648
G C + L+ GT I I D+++ F H IT+I YY +
Sbjct: 350 GCSLTCAQFHPDGLIFGTGTMDSHIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLAT 409
Query: 649 SATDGSIKIWQLSNQELFETFRSE---PIKASVFSKGD--LAVKGLDI 777
+A D S+K+W L + F+T + + +K+ +F + LA+ G D+
Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDV 457
>sp|Q09866|YAG1_SCHPO Hypothetical WD-repeat protein C12G12.01c in chromosome I
Length = 905
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/180 (23%), Positives = 69/180 (38%), Gaps = 1/180 (0%)
Frame = +1
Query: 142 NFDANGNKFGMGDSEGNFSLFHFSYADNSRAQYFQTRCPHKGVLDFCFINSSSLVATAGS 321
+F N G G S GN SL + + FQ ++V +
Sbjct: 52 SFHGNNEILGAGSSTGNISLLSVKHPE------FQ-----------------AVVTPGYA 88
Query: 322 SALHGLPSVNQLHAVGGGNFDTNSVNISMWDVLLPSGRNQVRNLSDPQLAIGVVALCYVS 501
+ L H V G N ++ +WD+ + L GV ++CY
Sbjct: 89 RPCNSLAFSETEHLVAGFAKSRNESSLKLWDLNSLLSDPKSSPLMQSSTLDGVSSVCYKK 148
Query: 502 RYELLLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQ-YYFVSSATDGSIKIW 678
LLL G+ + IID RQ ++ ++ + + I +DP YF +++ DG I I+
Sbjct: 149 DTPLLLTGSTSRSVHIIDTRQ-QLDSVSSVNTQYYSNIVVDPFSPNYFAANSYDGDIAIF 207
>sp|Q8N3Y1|FBXW8_HUMAN F-box/WD-repeat protein 8 (F-box and WD-40 domain protein 8) (F-box
only protein 29)
Length = 598
Score = 44.3 bits (103), Expect = 4e-04
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +1
Query: 511 LLLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQL-S 687
L+++G G + I D+R I AH ++A+++D + VS +G + +W
Sbjct: 447 LMVSGNMDGRVRIHDLRSGNIALSLSAHQLRVSAVQMD--DWKIVSGGEEGLVSVWDYRM 504
Query: 688 NQELFETFRSEPIKASVFSKGDL 756
NQ+L+E + P++ FS L
Sbjct: 505 NQKLWEVYSGHPVQHISFSSHSL 527
>sp|Q8C7V3|UTP15_MOUSE U3 small nucleolar RNA-associated protein 15 homolog
(Src-associated protein SAW)
Length = 528
Score = 43.9 bits (102), Expect = 5e-04
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Frame = +1
Query: 508 ELLLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQLS 687
+LL+AG+ G + + DI F+ H + + Y+ VS A D ++K+W +
Sbjct: 93 QLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVDFTADNYHVVSGADDYTVKLWDIP 152
Query: 688 NQELFETFR--SEPIKASVFSK--GDLAVKG 768
N + TF+ S+ ++ SK DL V G
Sbjct: 153 NSKEILTFKEHSDYVRCGCASKLNPDLFVTG 183
>sp|Q96DI7|WDR57_HUMAN WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5
snRNP-specific 40 kDa protein) (38 kDa splicing factor)
Length = 357
Score = 43.5 bits (101), Expect = 7e-04
Identities = 20/95 (21%), Positives = 46/95 (48%)
Frame = +1
Query: 400 ISMWDVLLPSGRNQVRNLSDPQLAIGVVALCYVSRYELLLAGTRKGEIAIIDIRQNKIQN 579
+ +WD+ + +N V+A+ + + +++G +I + D+RQNK+
Sbjct: 176 VKLWDIRKKAAIQTFQNTYQ------VLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTY 229
Query: 580 IFQAHDSCITAIKLDPLQYYFVSSATDGSIKIWQL 684
+ H +T + L Y +S+A D ++++W +
Sbjct: 230 TMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 34.3 bits (77), Expect = 0.40
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Frame = +1
Query: 490 CYVSRY--ELLLAGTRKGEIAIIDIRQNKIQNIFQAHDSCITAIKLDPLQYYFVSSATDG 663
CY +R +L+ G+ G + + DIR+ FQ + + A+ + +S D
Sbjct: 157 CYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDN 215
Query: 664 SIKIWQLSNQELFETFR 714
IK+W L +L T R
Sbjct: 216 DIKVWDLRQNKLTYTMR 232
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,242,654
Number of Sequences: 369166
Number of extensions: 1727180
Number of successful extensions: 5590
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4854
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5547
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7405750800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)