Planaria EST Database

DrC_00649

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00649
         (1177 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9VT65|CANB_DROME  Calpain B (Calcium-activated neutral p...   328   2e-89
sp|O35920|CAN9_RAT  Calpain-9 (Digestive tract-specific calp...   285   2e-76
sp|P00789|CANX_CHICK  Calpain-1 catalytic subunit (Calpain-1...   281   2e-75
sp|Q9D805|CAN9_MOUSE  Calpain-9 (Digestive tract-specific ca...   281   3e-75
sp|O14815|CAN9_HUMAN  Calpain-9 (Digestive tract-specific ca...   280   4e-75
sp|Q9GLG7|CAN3_MACFA  Calpain-3 (Calpain L3) (Calpain p94) (...   280   6e-75
sp|P20807|CAN3_HUMAN  Calpain-3 (Calpain L3) (Calpain p94) (...   278   2e-74
sp|P43368|CAN3_PIG  Calpain-3 (Calpain L3) (Calpain p94) (Ca...   276   8e-74
sp|Q9TTH8|CAN3_SHEEP  Calpain-3 (Calpain L3) (Calpain p94) (...   275   1e-73
sp|P16259|CAN3_RAT  Calpain-3 (Calpain L3) (Calpain p94) (Ca...   275   2e-73

>sp|Q9VT65|CANB_DROME Calpain B (Calcium-activated neutral proteinase B) (CANP B)
            [Contains: Calpain B catalytic subunit 1; Calpain B
            catalytic subunit 2]
          Length = 925

 Score =  328 bits (840), Expect = 2e-89
 Identities = 165/392 (42%), Positives = 243/392 (61%), Gaps = 2/392 (0%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WMSFQDF+ +F+++EIC+L P SL  DQ     + +WEM +  GEW   + AGGCRNFL+
Sbjct: 539  WMSFQDFLNHFDRVEICNLSPDSLTEDQQHSS-RRKWEMSMFEGEWTSGVTAGGCRNFLE 597

Query: 182  TFWTNPQFRVKXXXXXXXXXXNLGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDENQ 361
            TFW NPQ+ +              T IV LMQK+ R +R  G++  TIG+AIY L D + 
Sbjct: 598  TFWHNPQYIISLEDPDDEDDDGKCTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLTDRDM 657

Query: 362  G--PLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMRIFS 535
               P  +NFFKY ASVA++P FIN REVC R KLPPG Y+IVPSTF+PN+E  F++R+FS
Sbjct: 658  QVKPQGLNFFKYRASVARSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFS 717

Query: 536  EKPYESGELDEQTAMVPTESSPEANKTATSVPAKAITPADDAQIAALRDSFNQIAGQDLE 715
            E      E D++     T+     ++ A S+P       DD Q  ALR  F+ +AG D E
Sbjct: 718  ETRNNMEENDDEVGFGETD-----DRIAPSLPPPTPKEEDDPQRIALRRLFDSVAGSDEE 772

Query: 716  IDAYELQDILNTXXXXXXXXXXXXXXXXSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDL 895
            +D  EL+ IL+                 S +  +SMVAM+D D+SG+LGF+EF+ L TD+
Sbjct: 773  VDWQELKRILD----HSMRDVMVGSDGFSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDI 828

Query: 896  RLWKEAFKKFDQDKSGNFNSYELRLCLNSVGFRLSNKILNSLVMRFANKEGLILFDDYIL 1075
              W+  FK +D  ++G+ + + LR  LNS G+ L+N++LN+L  R+ ++EG I FDD+++
Sbjct: 829  AKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGSREGQIPFDDFLM 888

Query: 1076 CCVRLKTIFETYKSQPHDSTDRAMFDQDTFIQ 1171
            C ++++T  E ++ +  D++D A F+ D +++
Sbjct: 889  CAIKVRTFIEMFRERDTDNSDTAFFNLDDWLE 920

>sp|O35920|CAN9_RAT Calpain-9 (Digestive tract-specific calpain) (nCL-4)
          Length = 674

 Score =  285 bits (728), Expect = 2e-76
 Identities = 152/372 (40%), Positives = 227/372 (61%), Gaps = 1/372 (0%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WM+F+DF  +F+K+EIC+L P +LE + L      +WE+ +  G W +   AGGCRNFLD
Sbjct: 300  WMAFEDFKTHFDKVEICNLTPDALEDNTL-----HKWEVTIHQGSWVRGSTAGGCRNFLD 354

Query: 182  TFWTNPQFRVKXXXXXXXXXXNLGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDENQ 361
            TFWTNPQ  +K             T +  LMQKD R+ ++ G    TIGYAIYQ  D++ 
Sbjct: 355  TFWTNPQ--IKLSLTERDEGQEGCTFLAALMQKDRRRLKRFGANMLTIGYAIYQCPDKD- 411

Query: 362  GPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMRIFSEK 541
            G L+ +FF+Y+AS+A++ +FINLREV GR +LPPG Y+++PSTFEP+QEA F +RIFSEK
Sbjct: 412  GHLNRDFFRYHASLARSKTFINLREVSGRFQLPPGDYILIPSTFEPHQEADFCLRIFSEK 471

Query: 542  PYESGELDEQTAM-VPTESSPEANKTATSVPAKAITPADDAQIAALRDSFNQIAGQDLEI 718
               + +LDE   + +P    P   +  T          ++ Q  AL   F +IAG+D+E+
Sbjct: 472  KAVTQDLDENIDIDLPELPKPTPQEEETE---------EERQFRAL---FRRIAGEDMEV 519

Query: 719  DAYELQDILNTXXXXXXXXXXXXXXXXSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLR 898
             A EL+ +LN                 S+ + ++++++MD   +GK+ F+EF+V W  LR
Sbjct: 520  SAEELEYVLNAVLQKKTALKFKRLRL-SLLSCRNIISLMDTSGNGKMEFEEFRVFWDKLR 578

Query: 899  LWKEAFKKFDQDKSGNFNSYELRLCLNSVGFRLSNKILNSLVMRFANKEGLILFDDYILC 1078
             W + F +FD DKSG  +SYELR  L + GF+L + +L  +V+R+A++   + FDDY+ C
Sbjct: 579  YWMDLFLQFDVDKSGTMSSYELRTALKAAGFQLGSHLLQLIVLRYADENLQLDFDDYLNC 638

Query: 1079 CVRLKTIFETYK 1114
             VRL+     ++
Sbjct: 639  LVRLENASRVFQ 650

>sp|P00789|CANX_CHICK Calpain-1 catalytic subunit (Calpain-1 large subunit)
            (Calcium-activated neutral proteinase) (CANP) (Mu/M-type)
          Length = 705

 Score =  281 bits (720), Expect = 2e-75
 Identities = 149/390 (38%), Positives = 233/390 (59%), Gaps = 6/390 (1%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WMSF+DF++ F ++EIC+L P +L  D+L     SRW   +  G W++   AGGCRN   
Sbjct: 328  WMSFRDFMREFSRLEICNLTPDALTKDEL-----SRWHTQVFEGTWRRGSTAGGCRNNPA 382

Query: 182  TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
            TFW NPQF++K          +    + +V LMQK  R+ R+ G + +TIG+A+Y++ +E
Sbjct: 383  TFWINPQFKIKLLEEDDDPGDDEVACSFLVALMQKHRRRERRVGGDMHTIGFAVYEVPEE 442

Query: 356  NQGPLDVN----FFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLM 523
             QG  +V+    FF  N S A++ +FINLREV  + +LPPG Y++VPSTFEP++EA F++
Sbjct: 443  AQGSQNVHLKKDFFLRNQSRARSETFINLREVSNQIRLPPGEYIVVPSTFEPHKEADFIL 502

Query: 524  RIFSEKPYESGELDEQTAMVPTESSPEANKTATSVPAKAITPADDAQIAALRDSFNQIAG 703
            R+F+EK  ++ ELDE+ +             A     + IT  D       ++ F Q+AG
Sbjct: 503  RVFTEKQSDTAELDEEIS-------------ADLADEEEITEDDIED--GFKNMFQQLAG 547

Query: 704  QDLEIDAYELQDILNTXXXXXXXXXXXXXXXXSIETSKSMVAMMDYDQSGKLGFDEFKVL 883
            +D+EI  +EL+ ILN                 S+++ ++MV +MD D S +LG  EF++L
Sbjct: 548  EDMEISVFELKTILNRVIARHKDLKTDGF---SLDSCRNMVNLMDKDGSARLGLVEFQIL 604

Query: 884  WTDLRLWKEAFKKFDQDKSGNFNSYELRLCLNSVGFRLSNKILNSLVMRFANKEGLILFD 1063
            W  +R W   F+++D DKSG  +SYE+R+ L S GF+L+NK+   +V R+A+ E  + FD
Sbjct: 605  WNKIRSWLTIFRQYDLDKSGTMSSYEMRMALESAGFKLNNKLHQVVVARYADAETGVDFD 664

Query: 1064 DYILCCVRLKTIFETYKSQPHDSTDRAMFD 1153
            +++ C V+L+T+F  + S   D T  A+ +
Sbjct: 665  NFVCCLVKLETMFRFFHSMDRDGTGTAVMN 694

>sp|Q9D805|CAN9_MOUSE Calpain-9 (Digestive tract-specific calpain) (nCL-4)
          Length = 690

 Score =  281 bits (719), Expect = 3e-75
 Identities = 155/390 (39%), Positives = 231/390 (59%), Gaps = 1/390 (0%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WM+F+DF  +F+K+EIC+L P +LE   L      RWE+ +  G W +   AGGCRNFLD
Sbjct: 318  WMAFKDFKIHFDKVEICNLTPDALEDSAL-----HRWEVTIHQGSWVRGSTAGGCRNFLD 372

Query: 182  TFWTNPQFRVKXXXXXXXXXXNLGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDENQ 361
            TFWTNPQ  +K             T +  LMQKD R+ ++ G    TIGYAIYQ  D++ 
Sbjct: 373  TFWTNPQ--IKLSLTERDEGQEGCTFLAALMQKDRRRLKRFGANMLTIGYAIYQCPDKD- 429

Query: 362  GPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMRIFSEK 541
            G L  +FF+Y+AS+A++ +FINLREV  R +LPPG Y+++PSTFEP+QEA F +RIFSEK
Sbjct: 430  GHLSRDFFRYHASLARSKTFINLREVSERFQLPPGDYILIPSTFEPHQEADFCLRIFSEK 489

Query: 542  PYESGELDEQTAM-VPTESSPEANKTATSVPAKAITPADDAQIAALRDSFNQIAGQDLEI 718
               + +LDE   + +P    P   +  T          ++ Q  AL   F ++AG+D+E+
Sbjct: 490  RAVTRDLDENIDIDLPELPKPTPQEEETE---------EEQQFRAL---FQRVAGEDMEV 537

Query: 719  DAYELQDILNTXXXXXXXXXXXXXXXXSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLR 898
             A EL+ +LN                 S+ + ++++++MD   +GKL F+EF+V W  L+
Sbjct: 538  SAEELEYVLNAVLQKKTALKFKRL---SLLSCRNIISLMDTSGNGKLEFEEFRVFWDKLK 594

Query: 899  LWKEAFKKFDQDKSGNFNSYELRLCLNSVGFRLSNKILNSLVMRFANKEGLILFDDYILC 1078
             W + F +FD DKSG  +SYELR  L + GF+L   +L  +V+R+A+++  + FDDY+ C
Sbjct: 595  HWMDLFLQFDVDKSGTMSSYELRTALKAAGFQLGGHLLQLIVLRYADEDLQLDFDDYLNC 654

Query: 1079 CVRLKTIFETYKSQPHDSTDRAMFDQDTFI 1168
             VRL+     ++S    + D    + + FI
Sbjct: 655  LVRLENASRVFQSLSVKNKDFIHLNINEFI 684

>sp|O14815|CAN9_HUMAN Calpain-9 (Digestive tract-specific calpain) (nCL-4) (CG36 protein)
          Length = 690

 Score =  280 bits (717), Expect = 4e-75
 Identities = 153/374 (40%), Positives = 225/374 (60%), Gaps = 2/374 (0%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WM+F+DF  +F+K+EIC+L P +LE D +      +WE+ +  G W +   AGGCRNFLD
Sbjct: 318  WMAFKDFKAHFDKVEICNLTPDALEEDAI-----HKWEVTVHQGSWVRGSTAGGCRNFLD 372

Query: 182  TFWTNPQFRVKXXXXXXXXXXNLGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDENQ 361
            TFWTNPQ  +K             + +V LMQKD RK ++ G    TIGYAIY+  D+++
Sbjct: 373  TFWTNPQ--IKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPDKDE 430

Query: 362  GPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMRIFSEK 541
              L+ +FF+Y+AS A++ +FINLREV  R KLPPG Y+++PSTFEP+QEA F +RIFSEK
Sbjct: 431  H-LNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEK 489

Query: 542  PYESGELDEQTAMVPTESSPEANKTATSVPAKAITPADDA--QIAALRDSFNQIAGQDLE 715
               + ++D    +      PE  K          TP D    +    R  F Q+AG+D+E
Sbjct: 490  KAITRDMDGNVDI----DLPEPPKP---------TPPDQETEEEQRFRALFEQVAGEDME 536

Query: 716  IDAYELQDILNTXXXXXXXXXXXXXXXXSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDL 895
            + A EL+ +LN                 S+ + K+++++MD   +GKL FDEFKV W  L
Sbjct: 537  VTAEELEYVLNAVLQKKKDIKFKKL---SLISCKNIISLMDTSGNGKLEFDEFKVFWDKL 593

Query: 896  RLWKEAFKKFDQDKSGNFNSYELRLCLNSVGFRLSNKILNSLVMRFANKEGLILFDDYIL 1075
            + W   F +FD DKSG  ++YELR  L + GF+LS+ +L  +V+R+A++E  + FDD++ 
Sbjct: 594  KQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLN 653

Query: 1076 CCVRLKTIFETYKS 1117
            C VRL+     +++
Sbjct: 654  CLVRLENASRVFQA 667

>sp|Q9GLG7|CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
            proteinase 3) (CANP 3) (Muscle-specific calcium-activated
            neutral protease 3) (Cn94)
          Length = 815

 Score =  280 bits (716), Expect = 6e-75
 Identities = 156/407 (38%), Positives = 232/407 (57%), Gaps = 31/407 (7%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WMS++DF+ +F K+EIC+L   +L+SD+L       W + +  G W +  +AGGCRNF D
Sbjct: 398  WMSYEDFIYHFTKLEICNLTADALQSDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 452

Query: 182  TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
            TFWTNPQ+R+K          +  + + +V LMQK+ RK RK G   +TIG+AIY++  E
Sbjct: 453  TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE 512

Query: 356  ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
               N+  L  +FF YNAS A++ ++IN+REV  R +LPP  YVIVPST+EP+QE  F++R
Sbjct: 513  MHGNRQHLQKDFFLYNASRARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILR 572

Query: 527  IFSEKPYESGELDEQTAM--------------------VPTESSPEANKTA------TSV 628
            +FSEK   S E++   ++                    V  ES     KT+      +  
Sbjct: 573  VFSEKRNLSEEVENTISVDRPVPIIFVSDRANSNKELGVDQESEEGKGKTSPDKQEQSPQ 632

Query: 629  PAKAITPADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTXXXXXXXXXXXXXXXXSIE 808
            P    +  +  +    R+ F QIAG D+EI A EL+ +LNT                ++E
Sbjct: 633  PQPGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGF---TLE 689

Query: 809  TSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFDQDKSGNFNSYELRLCLNSVG 988
            + +SM+A+MD D SGKL   EF  LW  ++ W++ FK +D D+SG  NSYE+R  +N  G
Sbjct: 690  SCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAG 749

Query: 989  FRLSNKILNSLVMRFANKEGLILFDDYILCCVRLKTIFETYKSQPHD 1129
            F L+N++ + + MR+A+K   I FD +I C VRL+ +F  + +   D
Sbjct: 750  FHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKD 796

>sp|P20807|CAN3_HUMAN Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
            proteinase 3) (CANP 3) (Muscle-specific calcium-activated
            neutral protease 3) (nCL-1)
          Length = 821

 Score =  278 bits (711), Expect = 2e-74
 Identities = 156/413 (37%), Positives = 232/413 (56%), Gaps = 37/413 (8%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WMS++DF+ +F K+EIC+L   +L+SD+L       W + +  G W +  +AGGCRNF D
Sbjct: 398  WMSYEDFIYHFTKLEICNLTADALQSDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 452

Query: 182  TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
            TFWTNPQ+R+K          +  + + +V LMQK+ RK RK G   +TIG+AIY++  E
Sbjct: 453  TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKE 512

Query: 356  ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
               N+  L  +FF YNAS A++ ++IN+REV  R +LPP  YVIVPST+EP+QE  F++R
Sbjct: 513  MHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILR 572

Query: 527  IFSEKPYESGELDEQTAM--------------------------VPTESSPEANKTA--- 619
            +FSEK   S E++   ++                          V  ES     KT+   
Sbjct: 573  VFSEKRNLSEEVENTISVDRPVKKKKTKPIIFVSDRANSNKELGVDQESEEGKGKTSPDK 632

Query: 620  ---TSVPAKAITPADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTXXXXXXXXXXXXX 790
               +  P    +  +  +    R+ F QIAG D+EI A EL+ +LNT             
Sbjct: 633  QKQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNT---VVNKHKDLKT 689

Query: 791  XXXSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFDQDKSGNFNSYELRL 970
               ++E+ +SM+A+MD D SGKL   EF  LW  ++ W++ FK +D D+SG  NSYE+R 
Sbjct: 690  HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 749

Query: 971  CLNSVGFRLSNKILNSLVMRFANKEGLILFDDYILCCVRLKTIFETYKSQPHD 1129
             +N  GF L+N++ + + MR+A+K   I FD +I C VRL+ +F  + +   D
Sbjct: 750  AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKD 802

>sp|P43368|CAN3_PIG Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
            proteinase 3) (CANP 3) (Muscle-specific calcium-activated
            neutral protease 3) (nCL-1)
          Length = 821

 Score =  276 bits (706), Expect = 8e-74
 Identities = 156/413 (37%), Positives = 233/413 (56%), Gaps = 37/413 (8%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WMS+ DF+ +F K+EIC+L   +LESD+L       W + +  G W +  +AGGCRNF D
Sbjct: 398  WMSYDDFIYHFTKLEICNLTADALESDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 452

Query: 182  TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
            TFWTNPQ+R+K          +  + + +V LMQK+ RK RK G   +TIG+AIY++  E
Sbjct: 453  TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE 512

Query: 356  ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
               N+  L  +FF YNAS A++ ++IN+REV  R +LPP  YVIVPST+EP+QE  F++R
Sbjct: 513  MHGNKQHLQKDFFLYNASKARSRTYINMREVSERFRLPPSEYVIVPSTYEPHQEGEFILR 572

Query: 527  IFSEKPYESGELDEQTAM--------------------------VPTESSPEANKTA--- 619
            +FSEK   S E++   ++                          V  ES    +KT+   
Sbjct: 573  VFSEKRNLSEEVENTISVDRPVRKKKTKPIIFVSDRANSNKELGVDQESEEGQDKTSPDK 632

Query: 620  ---TSVPAKAITPADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTXXXXXXXXXXXXX 790
               +  P  + T  +  +    R+ F QIAG D+EI A EL+++LN              
Sbjct: 633  QEKSPKPEPSNTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLN---RVVNKHKDLKT 689

Query: 791  XXXSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFDQDKSGNFNSYELRL 970
               ++E+ +SM+A+MD D SG+L   EF  LW  ++ W++ FK +D D+SG  NSYE+R 
Sbjct: 690  EGFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKSWQKIFKHYDTDQSGTINSYEMRN 749

Query: 971  CLNSVGFRLSNKILNSLVMRFANKEGLILFDDYILCCVRLKTIFETYKSQPHD 1129
             +N  GF L+N++ + + MR+A+K   I FD +I C VRL+ +F  + +   D
Sbjct: 750  AVNDAGFHLNNQLYDIITMRYADKYMNIDFDSFICCFVRLEGMFRAFNAFDKD 802

>sp|Q9TTH8|CAN3_SHEEP Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
            proteinase 3) (CANP 3) (Muscle-specific calcium-activated
            neutral protease 3) (nCL-1)
          Length = 822

 Score =  275 bits (704), Expect = 1e-73
 Identities = 155/413 (37%), Positives = 232/413 (56%), Gaps = 37/413 (8%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WMS+ DF+ +F K+EIC+L   +LESD+L       W + +  G W +  +AGGCRNF D
Sbjct: 399  WMSYDDFIYHFTKLEICNLTADALESDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 453

Query: 182  TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
            TFWTNPQ+R+K          +  + + +V LMQK+ RK RK G   +TIG+AIY++  E
Sbjct: 454  TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE 513

Query: 356  ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
               N+  L  +FF YNAS A++ ++IN+REV  R +LPP  YVIVPST+EP+QE  F++R
Sbjct: 514  MHGNKQHLQKDFFLYNASKARSRTYINMREVSERFRLPPSEYVIVPSTYEPHQEGEFILR 573

Query: 527  IFSEKPYESGELDEQTAM------------------------VPTESSPEANKTATSVPA 634
            +FSEK   S E++   ++                        +  +   E  K  TS   
Sbjct: 574  VFSEKRNLSEEVENTISVDRPVKKKKPKPIIFGSDRANSNKELGVDQESEEGKDNTSPDK 633

Query: 635  KAITPA--------DDAQIAALRDSFNQIAGQDLEIDAYELQDILNTXXXXXXXXXXXXX 790
            +A +P         +  +    R+ F QIAG D+EI A EL+++LN              
Sbjct: 634  QAKSPQLKPGNIDQESKEQRQFRNIFRQIAGDDMEICADELKNVLNRVVNKHKDLKTQGF 693

Query: 791  XXXSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFDQDKSGNFNSYELRL 970
               ++E+ +SM+A+MD D SG+L   EF  LW  ++ W++ FK +D D+SG  NSYE+R 
Sbjct: 694  ---TLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKTWQKIFKHYDTDQSGTINSYEMRN 750

Query: 971  CLNSVGFRLSNKILNSLVMRFANKEGLILFDDYILCCVRLKTIFETYKSQPHD 1129
             +N  GF L+N++ + + MR+A+K   I FD +I C VRL+ +F  + +   D
Sbjct: 751  AVNDAGFHLNNQLYDIITMRYADKYMNIDFDSFICCFVRLEGMFRAFNAFDKD 803

>sp|P16259|CAN3_RAT Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
            proteinase 3) (CANP 3) (Muscle-specific calcium-activated
            neutral protease 3)
          Length = 821

 Score =  275 bits (702), Expect = 2e-73
 Identities = 156/413 (37%), Positives = 230/413 (55%), Gaps = 37/413 (8%)
 Frame = +2

Query: 2    WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
            WMS+ DFV +F K+EIC+L   +LESD+L       W + +  G W +  +AGGCRNF D
Sbjct: 398  WMSYDDFVYHFTKLEICNLTADALESDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 452

Query: 182  TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
            TFWTNPQ+R+K          +  + + +V LMQK+ RK RK G   +TIG+AIY++  E
Sbjct: 453  TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE 512

Query: 356  ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
               N+  L  +FF YNAS A++ ++IN+REV  R +LPP  YVIVPST+EP+QE  F++R
Sbjct: 513  MHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILR 572

Query: 527  IFSEKPYESGELDEQTAM--------------------------VPTESSPEANKTA--- 619
            +FSEK   S E +   ++                          V  E+    +KT    
Sbjct: 573  VFSEKRNLSEEAENTISVDRPVKKKKNKPIIFVSDRANSNKELGVDQEAEEGKDKTGPDK 632

Query: 620  ---TSVPAKAITPADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTXXXXXXXXXXXXX 790
               +  P    T  +  +    R+ F QIAG D+EI A EL+++LNT             
Sbjct: 633  QGESPQPRPGHTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNT---VVNKHKDLKT 689

Query: 791  XXXSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFDQDKSGNFNSYELRL 970
               ++E+ +SM+A+MD D SG+L   EF  LW  ++ W++ FK +D D SG  NSYE+R 
Sbjct: 690  QGFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSGTINSYEMRN 749

Query: 971  CLNSVGFRLSNKILNSLVMRFANKEGLILFDDYILCCVRLKTIFETYKSQPHD 1129
             +N  GF L++++ + + MR+A+K   I FD +I C VRL+ +F  + +   D
Sbjct: 750  AVNDAGFHLNSQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKD 802

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 121,768,904
Number of Sequences: 369166
Number of extensions: 2310392
Number of successful extensions: 6220
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5617
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6010
length of database: 68,354,980
effective HSP length: 113
effective length of database: 47,479,925
effective search space used: 13199419150
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00649

  1. Dr_sW_017_C08
  2. Dr_sW_002_I04