Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_C08
(923 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VT65|CANB_DROME Calpain B (Calcium-activated neutral p... 275 2e-73
sp|O35920|CAN9_RAT Calpain-9 (Digestive tract-specific calp... 245 1e-64
sp|O14815|CAN9_HUMAN Calpain-9 (Digestive tract-specific ca... 240 5e-63
sp|Q9GLG7|CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (... 239 1e-62
sp|Q9D805|CAN9_MOUSE Calpain-9 (Digestive tract-specific ca... 238 2e-62
sp|P20807|CAN3_HUMAN Calpain-3 (Calpain L3) (Calpain p94) (... 237 4e-62
sp|P16259|CAN3_RAT Calpain-3 (Calpain L3) (Calpain p94) (Ca... 236 5e-62
sp|P43368|CAN3_PIG Calpain-3 (Calpain L3) (Calpain p94) (Ca... 236 5e-62
sp|Q92178|CAN2_CHICK Calpain-2 catalytic subunit (Calpain-2... 235 1e-61
sp|Q9TTH8|CAN3_SHEEP Calpain-3 (Calpain L3) (Calpain p94) (... 235 2e-61
>sp|Q9VT65|CANB_DROME Calpain B (Calcium-activated neutral proteinase B) (CANP B)
[Contains: Calpain B catalytic subunit 1; Calpain B
catalytic subunit 2]
Length = 925
Score = 275 bits (702), Expect = 2e-73
Identities = 142/309 (45%), Positives = 194/309 (62%), Gaps = 2/309 (0%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WMSFQDF+ +F+++EIC+L P SL DQ + +WEM + GEW + AGGCRNFL+
Sbjct: 539 WMSFQDFLNHFDRVEICNLSPDSLTEDQQHSS-RRKWEMSMFEGEWTSGVTAGGCRNFLE 597
Query: 182 TFWTNPQFRVKXXXXXXXXXXNLGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDENQ 361
TFW NPQ+ + T IV LMQK+ R +R G++ TIG+AIY L D +
Sbjct: 598 TFWHNPQYIISLEDPDDEDDDGKCTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLTDRDM 657
Query: 362 G--PLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMRIFS 535
P +NFFKY ASVA++P FIN REVC R KLPPG Y+IVPSTF+PN+E F++R+FS
Sbjct: 658 QVKPQGLNFFKYRASVARSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFS 717
Query: 536 EKPYESGELDEQTAMVPTESSPEANKTATSVPAKAITPADDAQIAALRDSFNQIAGQDLE 715
E E D++ T+ ++ A S+P DD Q ALR F+ +AG D E
Sbjct: 718 ETRNNMEENDDEVGFGETD-----DRIAPSLPPPTPKEEDDPQRIALRRLFDSVAGSDEE 772
Query: 716 IDAYELQDILNTAFKKVCIDFKFDGFSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRL 895
+D EL+ IL+ + + V + DGFS + +SMVAM+D D+SG+LGF+EF+ L TD+
Sbjct: 773 VDWQELKRILDHSMRDVMVG--SDGFSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAK 830
Query: 896 WKEAFKKFD 922
W+ FK +D
Sbjct: 831 WRAVFKLYD 839
>sp|O35920|CAN9_RAT Calpain-9 (Digestive tract-specific calpain) (nCL-4)
Length = 674
Score = 245 bits (625), Expect = 1e-64
Identities = 131/309 (42%), Positives = 192/309 (62%), Gaps = 2/309 (0%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WM+F+DF +F+K+EIC+L P +LE + L +WE+ + G W + AGGCRNFLD
Sbjct: 300 WMAFEDFKTHFDKVEICNLTPDALEDNTL-----HKWEVTIHQGSWVRGSTAGGCRNFLD 354
Query: 182 TFWTNPQFRVKXXXXXXXXXXNLGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDENQ 361
TFWTNPQ +K T + LMQKD R+ ++ G TIGYAIYQ D++
Sbjct: 355 TFWTNPQ--IKLSLTERDEGQEGCTFLAALMQKDRRRLKRFGANMLTIGYAIYQCPDKD- 411
Query: 362 GPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMRIFSEK 541
G L+ +FF+Y+AS+A++ +FINLREV GR +LPPG Y+++PSTFEP+QEA F +RIFSEK
Sbjct: 412 GHLNRDFFRYHASLARSKTFINLREVSGRFQLPPGDYILIPSTFEPHQEADFCLRIFSEK 471
Query: 542 PYESGELDEQTAM-VPTESSPEANKTATSVPAKAITPADDAQIAALRDSFNQIAGQDLEI 718
+ +LDE + +P P + T ++ Q AL F +IAG+D+E+
Sbjct: 472 KAVTQDLDENIDIDLPELPKPTPQEEETE---------EERQFRAL---FRRIAGEDMEV 519
Query: 719 DAYELQDILNTAF-KKVCIDFKFDGFSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRL 895
A EL+ +LN KK + FK S+ + ++++++MD +GK+ F+EF+V W LR
Sbjct: 520 SAEELEYVLNAVLQKKTALKFKRLRLSLLSCRNIISLMDTSGNGKMEFEEFRVFWDKLRY 579
Query: 896 WKEAFKKFD 922
W + F +FD
Sbjct: 580 WMDLFLQFD 588
>sp|O14815|CAN9_HUMAN Calpain-9 (Digestive tract-specific calpain) (nCL-4) (CG36 protein)
Length = 690
Score = 240 bits (612), Expect = 5e-63
Identities = 132/309 (42%), Positives = 187/309 (60%), Gaps = 2/309 (0%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WM+F+DF +F+K+EIC+L P +LE D + +WE+ + G W + AGGCRNFLD
Sbjct: 318 WMAFKDFKAHFDKVEICNLTPDALEEDAI-----HKWEVTVHQGSWVRGSTAGGCRNFLD 372
Query: 182 TFWTNPQFRVKXXXXXXXXXXNLGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDENQ 361
TFWTNPQ +K + +V LMQKD RK ++ G TIGYAIY+ D+++
Sbjct: 373 TFWTNPQ--IKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGYAIYECPDKDE 430
Query: 362 GPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMRIFSEK 541
L+ +FF+Y+AS A++ +FINLREV R KLPPG Y+++PSTFEP+QEA F +RIFSEK
Sbjct: 431 H-LNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEK 489
Query: 542 PYESGELDEQTAMVPTESSPEANKTATSVPAKAITPADD--AQIAALRDSFNQIAGQDLE 715
+ ++D + PE K TP D + R F Q+AG+D+E
Sbjct: 490 KAITRDMDGNVDI----DLPEPPKP---------TPPDQETEEEQRFRALFEQVAGEDME 536
Query: 716 IDAYELQDILNTAFKKVCIDFKFDGFSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRL 895
+ A EL+ +LN +K D KF S+ + K+++++MD +GKL FDEFKV W L+
Sbjct: 537 VTAEELEYVLNAVLQKK-KDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQ 595
Query: 896 WKEAFKKFD 922
W F +FD
Sbjct: 596 WINLFLRFD 604
>sp|Q9GLG7|CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
proteinase 3) (CANP 3) (Muscle-specific calcium-activated
neutral protease 3) (Cn94)
Length = 815
Score = 239 bits (609), Expect = 1e-62
Identities = 134/338 (39%), Positives = 195/338 (57%), Gaps = 31/338 (9%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WMS++DF+ +F K+EIC+L +L+SD+L W + + G W + +AGGCRNF D
Sbjct: 398 WMSYEDFIYHFTKLEICNLTADALQSDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 452
Query: 182 TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
TFWTNPQ+R+K + + + +V LMQK+ RK RK G +TIG+AIY++ E
Sbjct: 453 TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE 512
Query: 356 ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
N+ L +FF YNAS A++ ++IN+REV R +LPP YVIVPST+EP+QE F++R
Sbjct: 513 MHGNRQHLQKDFFLYNASRARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILR 572
Query: 527 IFSEKPYESGELDEQTAM--------------------VPTESSPEANKTA------TSV 628
+FSEK S E++ ++ V ES KT+ +
Sbjct: 573 VFSEKRNLSEEVENTISVDRPVPIIFVSDRANSNKELGVDQESEEGKGKTSPDKQEQSPQ 632
Query: 629 PAKAITPADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTAFKKVCIDFKFDGFSIETS 808
P + + + R+ F QIAG D+EI A EL+ +LNT K D K GF++E+
Sbjct: 633 PQPGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNK-HKDLKTHGFTLESC 691
Query: 809 KSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFD 922
+SM+A+MD D SGKL EF LW ++ W++ FK +D
Sbjct: 692 RSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYD 729
>sp|Q9D805|CAN9_MOUSE Calpain-9 (Digestive tract-specific calpain) (nCL-4)
Length = 690
Score = 238 bits (607), Expect = 2e-62
Identities = 129/308 (41%), Positives = 188/308 (61%), Gaps = 1/308 (0%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WM+F+DF +F+K+EIC+L P +LE L RWE+ + G W + AGGCRNFLD
Sbjct: 318 WMAFKDFKIHFDKVEICNLTPDALEDSAL-----HRWEVTIHQGSWVRGSTAGGCRNFLD 372
Query: 182 TFWTNPQFRVKXXXXXXXXXXNLGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDENQ 361
TFWTNPQ +K T + LMQKD R+ ++ G TIGYAIYQ D++
Sbjct: 373 TFWTNPQ--IKLSLTERDEGQEGCTFLAALMQKDRRRLKRFGANMLTIGYAIYQCPDKD- 429
Query: 362 GPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMRIFSEK 541
G L +FF+Y+AS+A++ +FINLREV R +LPPG Y+++PSTFEP+QEA F +RIFSEK
Sbjct: 430 GHLSRDFFRYHASLARSKTFINLREVSERFQLPPGDYILIPSTFEPHQEADFCLRIFSEK 489
Query: 542 PYESGELDEQTAM-VPTESSPEANKTATSVPAKAITPADDAQIAALRDSFNQIAGQDLEI 718
+ +LDE + +P P + T ++ Q AL F ++AG+D+E+
Sbjct: 490 RAVTRDLDENIDIDLPELPKPTPQEEETE---------EEQQFRAL---FQRVAGEDMEV 537
Query: 719 DAYELQDILNTAFKKVCIDFKFDGFSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLW 898
A EL+ +LN +K KF S+ + ++++++MD +GKL F+EF+V W L+ W
Sbjct: 538 SAEELEYVLNAVLQKKTA-LKFKRLSLLSCRNIISLMDTSGNGKLEFEEFRVFWDKLKHW 596
Query: 899 KEAFKKFD 922
+ F +FD
Sbjct: 597 MDLFLQFD 604
>sp|P20807|CAN3_HUMAN Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
proteinase 3) (CANP 3) (Muscle-specific calcium-activated
neutral protease 3) (nCL-1)
Length = 821
Score = 237 bits (604), Expect = 4e-62
Identities = 134/344 (38%), Positives = 195/344 (56%), Gaps = 37/344 (10%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WMS++DF+ +F K+EIC+L +L+SD+L W + + G W + +AGGCRNF D
Sbjct: 398 WMSYEDFIYHFTKLEICNLTADALQSDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 452
Query: 182 TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
TFWTNPQ+R+K + + + +V LMQK+ RK RK G +TIG+AIY++ E
Sbjct: 453 TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKE 512
Query: 356 ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
N+ L +FF YNAS A++ ++IN+REV R +LPP YVIVPST+EP+QE F++R
Sbjct: 513 MHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILR 572
Query: 527 IFSEKPYESGELDEQTAM--------------------------VPTESSPEANKTA--- 619
+FSEK S E++ ++ V ES KT+
Sbjct: 573 VFSEKRNLSEEVENTISVDRPVKKKKTKPIIFVSDRANSNKELGVDQESEEGKGKTSPDK 632
Query: 620 ---TSVPAKAITPADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTAFKKVCIDFKFDG 790
+ P + + + R+ F QIAG D+EI A EL+ +LNT K D K G
Sbjct: 633 QKQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNK-HKDLKTHG 691
Query: 791 FSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFD 922
F++E+ +SM+A+MD D SGKL EF LW ++ W++ FK +D
Sbjct: 692 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYD 735
>sp|P16259|CAN3_RAT Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
proteinase 3) (CANP 3) (Muscle-specific calcium-activated
neutral protease 3)
Length = 821
Score = 236 bits (603), Expect = 5e-62
Identities = 135/344 (39%), Positives = 194/344 (56%), Gaps = 37/344 (10%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WMS+ DFV +F K+EIC+L +LESD+L W + + G W + +AGGCRNF D
Sbjct: 398 WMSYDDFVYHFTKLEICNLTADALESDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 452
Query: 182 TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
TFWTNPQ+R+K + + + +V LMQK+ RK RK G +TIG+AIY++ E
Sbjct: 453 TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE 512
Query: 356 ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
N+ L +FF YNAS A++ ++IN+REV R +LPP YVIVPST+EP+QE F++R
Sbjct: 513 MHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILR 572
Query: 527 IFSEKPYESGELDEQTAM--------------------------VPTESSPEANKTA--- 619
+FSEK S E + ++ V E+ +KT
Sbjct: 573 VFSEKRNLSEEAENTISVDRPVKKKKNKPIIFVSDRANSNKELGVDQEAEEGKDKTGPDK 632
Query: 620 ---TSVPAKAITPADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTAFKKVCIDFKFDG 790
+ P T + + R+ F QIAG D+EI A EL+++LNT K D K G
Sbjct: 633 QGESPQPRPGHTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNTVVNK-HKDLKTQG 691
Query: 791 FSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFD 922
F++E+ +SM+A+MD D SG+L EF LW ++ W++ FK +D
Sbjct: 692 FTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKAWQKIFKHYD 735
>sp|P43368|CAN3_PIG Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
proteinase 3) (CANP 3) (Muscle-specific calcium-activated
neutral protease 3) (nCL-1)
Length = 821
Score = 236 bits (603), Expect = 5e-62
Identities = 134/344 (38%), Positives = 197/344 (57%), Gaps = 37/344 (10%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WMS+ DF+ +F K+EIC+L +LESD+L W + + G W + +AGGCRNF D
Sbjct: 398 WMSYDDFIYHFTKLEICNLTADALESDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 452
Query: 182 TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
TFWTNPQ+R+K + + + +V LMQK+ RK RK G +TIG+AIY++ E
Sbjct: 453 TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE 512
Query: 356 ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
N+ L +FF YNAS A++ ++IN+REV R +LPP YVIVPST+EP+QE F++R
Sbjct: 513 MHGNKQHLQKDFFLYNASKARSRTYINMREVSERFRLPPSEYVIVPSTYEPHQEGEFILR 572
Query: 527 IFSEKPYESGELDEQTAM--------------------------VPTESSPEANKTA--- 619
+FSEK S E++ ++ V ES +KT+
Sbjct: 573 VFSEKRNLSEEVENTISVDRPVRKKKTKPIIFVSDRANSNKELGVDQESEEGQDKTSPDK 632
Query: 620 ---TSVPAKAITPADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTAFKKVCIDFKFDG 790
+ P + T + + R+ F QIAG D+EI A EL+++LN K D K +G
Sbjct: 633 QEKSPKPEPSNTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNRVVNK-HKDLKTEG 691
Query: 791 FSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFD 922
F++E+ +SM+A+MD D SG+L EF LW ++ W++ FK +D
Sbjct: 692 FTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKSWQKIFKHYD 735
>sp|Q92178|CAN2_CHICK Calpain-2 catalytic subunit (Calpain-2 large subunit)
(Calcium-activated neutral proteinase 2) (CANP 2)
(Calpain M-type) (M-calpain) (Millimolar-calpain)
Length = 700
Score = 235 bits (600), Expect = 1e-61
Identities = 129/313 (41%), Positives = 184/313 (58%), Gaps = 6/313 (1%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WM+F DF++++ ++EIC+L P +L SD+ +W + +G W++ AGGCRN+ +
Sbjct: 325 WMAFNDFLRHYSRLEICNLTPDTLASDRY-----KKWSLLKLDGNWRRGATAGGCRNYPN 379
Query: 182 TFWTNPQFRVKXXXXXXXXXXNLG--TIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
TFWTNPQ+ +K G T ++GL+QK RK+RK G + +TIG+AIY++ E
Sbjct: 380 TFWTNPQYLIKLEEEDEDPDDPEGGCTFLIGLIQKHRRKQRKMGEDMHTIGFAIYEVPPE 439
Query: 356 NQGPLDV----NFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLM 523
G ++ NFF N + K+ +FINLREV R KLP G Y+IVPSTFEPN F +
Sbjct: 440 FSGQTNIHLSKNFFLTNKAREKSNTFINLREVLNRFKLPAGEYIIVPSTFEPNLNGDFCL 499
Query: 524 RIFSEKPYESGELDEQTAMVPTESSPEANKTATSVPAKAITPADDAQIAALRDSFNQIAG 703
R+FSEK S +D++ EAN T + I P + + F Q+AG
Sbjct: 500 RVFSEKNANSTVIDDEI---------EANFEETEIDEDDIEP-------SFKKLFGQLAG 543
Query: 704 QDLEIDAYELQDILNTAFKKVCIDFKFDGFSIETSKSMVAMMDYDQSGKLGFDEFKVLWT 883
D EI A+EL+ ILN K D K DGFSIET K MV ++D D SGKLG EF LWT
Sbjct: 544 SDAEISAFELRSILNKILAK-RQDIKSDGFSIETCKIMVDLLDNDGSGKLGLKEFHTLWT 602
Query: 884 DLRLWKEAFKKFD 922
++ +++ +++ D
Sbjct: 603 KIQKYQKIYREID 615
>sp|Q9TTH8|CAN3_SHEEP Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral
proteinase 3) (CANP 3) (Muscle-specific calcium-activated
neutral protease 3) (nCL-1)
Length = 822
Score = 235 bits (599), Expect = 2e-61
Identities = 133/344 (38%), Positives = 195/344 (56%), Gaps = 37/344 (10%)
Frame = +2
Query: 2 WMSFQDFVKNFEKMEICHLGPQSLESDQLGGKPKSRWEMCLENGEWKKRLNAGGCRNFLD 181
WMS+ DF+ +F K+EIC+L +LESD+L W + + G W + +AGGCRNF D
Sbjct: 399 WMSYDDFIYHFTKLEICNLTADALESDKL-----QTWTVSVNEGRWVRGCSAGGCRNFPD 453
Query: 182 TFWTNPQFRVKXXXXXXXXXXN--LGTIIVGLMQKDMRKRRKEGVEFYTIGYAIYQLKDE 355
TFWTNPQ+R+K + + + +V LMQK+ RK RK G +TIG+AIY++ E
Sbjct: 454 TFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE 513
Query: 356 ---NQGPLDVNFFKYNASVAKAPSFINLREVCGRHKLPPGTYVIVPSTFEPNQEAAFLMR 526
N+ L +FF YNAS A++ ++IN+REV R +LPP YVIVPST+EP+QE F++R
Sbjct: 514 MHGNKQHLQKDFFLYNASKARSRTYINMREVSERFRLPPSEYVIVPSTYEPHQEGEFILR 573
Query: 527 IFSEKPYESGELDEQTAM------------------------VPTESSPEANKTATSVPA 634
+FSEK S E++ ++ + + E K TS
Sbjct: 574 VFSEKRNLSEEVENTISVDRPVKKKKPKPIIFGSDRANSNKELGVDQESEEGKDNTSPDK 633
Query: 635 KAITP--------ADDAQIAALRDSFNQIAGQDLEIDAYELQDILNTAFKKVCIDFKFDG 790
+A +P + + R+ F QIAG D+EI A EL+++LN K D K G
Sbjct: 634 QAKSPQLKPGNIDQESKEQRQFRNIFRQIAGDDMEICADELKNVLNRVVNK-HKDLKTQG 692
Query: 791 FSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFD 922
F++E+ +SM+A+MD D SG+L EF LW ++ W++ FK +D
Sbjct: 693 FTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKTWQKIFKHYD 736
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,108,863
Number of Sequences: 369166
Number of extensions: 1840517
Number of successful extensions: 4994
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4615
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4808
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9462723610
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)