Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00646 (1017 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P36047|SDS22_YEAST Protein phosphatases PP1 regulatory s... 57 8e-08 sp|P39687|AN32A_HUMAN Acidic leucine-rich nuclear phosphopr... 54 7e-07 sp|Q86X45|LRRC6_HUMAN Leucine-rich repeat-containing protei... 54 7e-07 sp|P45969|YNZ9_CAEEL Hypothetical protein T09A5.9 in chromo... 54 9e-07 sp|O88978|LRRC6_MOUSE Leucine-rich repeat-containing protei... 53 1e-06 sp|Q4R3F0|LRRC6_MACFA Leucine-rich repeat-containing protein 6 51 5e-06 sp|P49911|AN32A_RAT Acidic leucine-rich nuclear phosphoprot... 47 7e-05 sp|P22194|SDS22_SCHPO Protein phosphatases PP1 regulatory s... 47 7e-05 sp|O35381|AN32A_MOUSE Acidic leucine-rich nuclear phosphopr... 47 7e-05 sp||P51122_1 [Segment 1 of 2] Acidic leucine-rich nuclear p... 47 7e-05
>sp|P36047|SDS22_YEAST Protein phosphatases PP1 regulatory subunit SDS22 Length = 338 Score = 57.0 bits (136), Expect = 8e-08 Identities = 49/152 (32%), Positives = 72/152 (47%), Gaps = 3/152 (1%) Frame = +2 Query: 2 RCLFLETNGICKLENLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENL 181 + L +++N + K+ENLE LT L LYLS N ITKIE L Sbjct: 206 KILSIQSNKLKKIENLEELTNLEELYLSHNF----------------------ITKIEGL 243 Query: 182 RDLPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDP-KVIDEIFSKMKSLRV 358 K T L + NK I+ LE L + N++ + N ID + + E S + L Sbjct: 244 EKNLKLTTLDVTSNK---ITSLENLNHLSNLTDIWASFNKIDQSFESLGENLSALSRLET 300 Query: 359 LYLQGNQC-IKNINNY-RKYTINICKHLTYLD 448 +YL+GN ++N +Y RK T+N+ L +D Sbjct: 301 IYLEGNPIQLENKTSYRRKLTMNLPPSLQKID 332
Score = 42.0 bits (97), Expect = 0.003 Identities = 37/124 (29%), Positives = 58/124 (46%) Frame = +2 Query: 44 NLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLRDLPKFTKLTLAHN 223 N+ LT+L L LS N I I+ I+KIENL L L L N Sbjct: 108 NVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLKNLELGGN 167 Query: 224 KIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLYLQGNQCIKNINNY 403 K+ +I + + N+ + L N I P++I+ +K+L++L +Q N+ +K I N Sbjct: 168 KVHSI-EPDSFEGLSNLEEIWLGKNSI--PRLIN--LHPLKNLKILSIQSNK-LKKIENL 221 Query: 404 RKYT 415 + T Sbjct: 222 EELT 225
>sp|P39687|AN32A_HUMAN Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Cerebellar leucine-rich acidic nuclear protein) (HLA-DR-associated protein I) (PHAPI) Length = 249 Score = 53.9 bits (128), Expect = 7e-07 Identities = 41/126 (32%), Positives = 69/126 (54%), Gaps = 2/126 (1%) Frame = +2 Query: 161 ITKIENLRDLPKFTKLTLAHNKIQTISDLEELIY-CDNISVLDLQHNLIDDPKVIDEIFS 337 +T I NL L K KL L+ N++ LE L C N++ L+L N I D I+ + Sbjct: 54 LTSIANLPKLNKLKKLELSDNRVS--GGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPL-K 110 Query: 338 KMKSLRVLYLQGNQCIKNINNYRKYTINICKHLTYLDERPVFEKDRAFAEA-FYRGGIDE 514 K+++L+ L L + + N+N+YR+ + LTYLD +K+ ++A Y G+D+ Sbjct: 111 KLENLKSLDLFNCE-VTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDD 169 Query: 515 EKKERD 532 E+++ D Sbjct: 170 EEEDED 175
>sp|Q86X45|LRRC6_HUMAN Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein) Length = 466 Score = 53.9 bits (128), Expect = 7e-07 Identities = 53/201 (26%), Positives = 90/201 (44%), Gaps = 1/201 (0%) Frame = +2 Query: 8 LFLETNGICKLENLEM-LTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLR 184 L L I +LE+++ +L+ LYL NLI KIEN+ Sbjct: 26 LSLHQQEIERLEHIDKWCRDLKILYLQNNLIG----------------------KIENVS 63 Query: 185 DLPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLY 364 L K L LA N I+ I +LE C+ ++ LDL N I + I + + L+ L+ Sbjct: 64 KLKKLEYLNLALNNIEKIENLEG---CEELAKLDLTVNFIGELSSIKNLQHNI-HLKELF 119 Query: 365 LQGNQCIKNINNYRKYTINICKHLTYLDERPVFEKDRAFAEAFYRGGIDEEKKERDRWVE 544 L GN C + ++YR++ + L +LD + + +R A Y I+ + +E+++ Sbjct: 120 LMGNPC-ASFDHYREFVVATLPQLKWLDGKEIEPSERIKALQDY-SVIEPQIREQEKDHC 177 Query: 545 AERERMNSSFQWLRERRAKIE 607 +R ++ Q + K E Sbjct: 178 LKRAKLKEEAQRKHQEEDKNE 198
>sp|P45969|YNZ9_CAEEL Hypothetical protein T09A5.9 in chromosome III Length = 326 Score = 53.5 bits (127), Expect = 9e-07 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 41/188 (21%) Frame = +2 Query: 8 LFLETNGICKLENLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLRD 187 L+L +N I K+ENLE LT+L+ L L N I +IE I ++E + Sbjct: 130 LYLVSNKIEKIENLEALTQLKLLELGDNRIKKIENIGHLVNLDELFIGKNKIRQLEGVET 189 Query: 188 LPKFTKLTLAHNKIQTISDLEEL-----IYCD--------------NISVLDLQHNLI-- 304 L K + L+L N+I I ++E+L +Y N+ +LD+ +N I Sbjct: 190 LQKLSVLSLPGNRIVKIENVEQLNNLKELYLSDQGLQDIHGVEPLTNLLLLDVANNEIKT 249 Query: 305 ---------------DDPKVID----EIFSKMKSLRVLYLQGNQCIKN-INNYRKYTINI 424 +D KV E SK+K L+ +YL+ N N N YR+ + Sbjct: 250 FSGVERLESLNDFWANDNKVESFSEIEQLSKLKGLQTVYLERNPFYFNDTNQYRRKVMMT 309 Query: 425 CKHLTYLD 448 +T +D Sbjct: 310 LTQVTQID 317
>sp|O88978|LRRC6_MOUSE Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein) Length = 473 Score = 53.1 bits (126), Expect = 1e-06 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 1/177 (0%) Frame = +2 Query: 8 LFLETNGICKLENLEM-LTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLR 184 L L I +LE+++ +L+ LYL NLI KIEN+ Sbjct: 26 LSLHQQEIERLEHIDKWCRDLKILYLQNNLIG----------------------KIENVS 63 Query: 185 DLPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLY 364 L K L LA N I+ I +LE C+ ++ LDL N I + + + + L+ L+ Sbjct: 64 KLKKLEYLNLALNNIERIENLEG---CEWLTKLDLTVNFIGELSSVKTLTHNI-HLKELF 119 Query: 365 LQGNQCIKNINNYRKYTINICKHLTYLDERPVFEKDRAFAEAFYRGGIDEEKKERDR 535 L GN C + + YR++ + + L +LD + + +R A Y ++++ +E+++ Sbjct: 120 LMGNPC-ADFDGYRQFVVVTLQQLKWLDGKEIERSERIQALQNYT-SVEQQIREQEK 174
>sp|Q4R3F0|LRRC6_MACFA Leucine-rich repeat-containing protein 6 Length = 466 Score = 51.2 bits (121), Expect = 5e-06 Identities = 53/201 (26%), Positives = 89/201 (44%), Gaps = 1/201 (0%) Frame = +2 Query: 8 LFLETNGICKLENLEM-LTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLR 184 L L I +LE+++ +L+ LYL NLI KIEN+ Sbjct: 26 LSLHQQEIERLEHIDKWCRDLKILYLQNNLIG----------------------KIENVS 63 Query: 185 DLPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLY 364 L K L LA N I+ I +LE C+ ++ LDL N I + I + + L+ L+ Sbjct: 64 KLKKLEYLNLALNNIEKIENLEG---CEELAKLDLTVNFIGELSSIKTLKHNI-HLKELF 119 Query: 365 LQGNQCIKNINNYRKYTINICKHLTYLDERPVFEKDRAFAEAFYRGGIDEEKKERDRWVE 544 L GN C ++YR++ + L +LD + + +R A Y I+ + +E+++ Sbjct: 120 LMGNPC-AFFDHYREFVVATLPQLKWLDGKGIEPSERIKALQEY-SIIEPQIREQEKDHC 177 Query: 545 AERERMNSSFQWLRERRAKIE 607 +R ++ Q + K E Sbjct: 178 LKRAKLKEEAQRKHQEEDKNE 198
>sp|P49911|AN32A_RAT Acidic leucine-rich nuclear phosphoprotein 32 family member A (Leucine-rich acidic nuclear protein) Length = 247 Score = 47.4 bits (111), Expect = 7e-05 Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 3/127 (2%) Frame = +2 Query: 161 ITKIENLRDLPKFTKLTLAHNKIQTISDLEELIY-CDNISVLDLQHNLIDDPKVIDEIFS 337 +T I NL L K KL L+ N+I DLE L C N+ L+L N I D I+ + Sbjct: 54 LTSISNLPKLNKLKKLELSENRIS--GDLEVLAEKCPNLKHLNLSGNKIKDLSTIEPL-K 110 Query: 338 KMKSLRVLYLQGNQCIKNINNYRKYTINICKHLTYLD--ERPVFEKDRAFAEAFYRGGID 511 K+++L+ L L + + N+N YR+ + + YLD +R E + E + + Sbjct: 111 KLENLKSLDLFNCE-VTNLNAYRENVFKLLPQVMYLDGYDRDNKEAPDSDVEGYVEDDDE 169 Query: 512 EEKKERD 532 E++ E + Sbjct: 170 EDEDEEE 176
>sp|P22194|SDS22_SCHPO Protein phosphatases PP1 regulatory subunit sds22 Length = 332 Score = 47.4 bits (111), Expect = 7e-05 Identities = 40/124 (32%), Positives = 57/124 (45%) Frame = +2 Query: 8 LFLETNGICKLENLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLRD 187 L L N I ++ENL+ + L L LS N I I I +IENL Sbjct: 87 LDLYDNLIVRIENLDNVKNLTYLDLSFNNIKTIRNINHLKGLENLFFVQNRIRRIENLEG 146 Query: 188 LPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLYL 367 L + T L L NKI+ I +L+ L+ N+ L + N I E F K++ L +L + Sbjct: 147 LDRLTNLELGGNKIRVIENLDTLV---NLEKLWVGKNKITK----FENFEKLQKLSLLSI 199 Query: 368 QGNQ 379 Q N+ Sbjct: 200 QSNR 203
Score = 45.4 bits (106), Expect = 3e-04 Identities = 43/182 (23%), Positives = 66/182 (36%), Gaps = 42/182 (23%) Frame = +2 Query: 8 LFLETNGICKLENLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLRD 187 LF N I ++ENLE L L L L N I IE ITK EN Sbjct: 131 LFFVQNRIRRIENLEGLDRLTNLELGGNKIRVIENLDTLVNLEKLWVGKNKITKFENFEK 190 Query: 188 LPKFTKLTLAHNKIQTISDLEELIYC--------------------DNISVLDLQHNLI- 304 L K + L++ N+I +L L +C +N+ +LD+ +N+I Sbjct: 191 LQKLSLLSIQSNRITQFENLACLSHCLRELYVSHNGLTSFSGIEVLENLEILDVSNNMIK 250 Query: 305 ---------------------DDPKVIDEIFSKMKSLRVLYLQGNQCIKNINNYRKYTIN 421 + I++ S +K L +Y +GN K + + Sbjct: 251 HLSYLAGLKNLVELWASNNELSSFQEIEDELSGLKKLETVYFEGNPLQKTNPAVYRNKVR 310 Query: 422 IC 427 +C Sbjct: 311 LC 312
>sp|O35381|AN32A_MOUSE Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Cerebellar leucine-rich acidic nuclear protein) Length = 247 Score = 47.4 bits (111), Expect = 7e-05 Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 3/127 (2%) Frame = +2 Query: 161 ITKIENLRDLPKFTKLTLAHNKIQTISDLEELIY-CDNISVLDLQHNLIDDPKVIDEIFS 337 +T I NL L K KL L+ N+I DLE L C N+ L+L N I D I+ + Sbjct: 54 LTSISNLPKLNKLKKLELSENRIS--GDLEVLAEKCPNLKHLNLSGNKIKDLSTIEPL-K 110 Query: 338 KMKSLRVLYLQGNQCIKNINNYRKYTINICKHLTYLD--ERPVFEKDRAFAEAFYRGGID 511 K+++L+ L L + + N+N YR+ + + YLD +R E + E + + Sbjct: 111 KLENLKSLDLFNCE-VTNLNAYRENVFKLLPQVMYLDGYDRDNKEAPDSDVEGYVEDDDE 169 Query: 512 EEKKERD 532 E++ E + Sbjct: 170 EDEDEEE 176
>sp||P51122_1 [Segment 1 of 2] Acidic leucine-rich nuclear phosphoprotein 32 family member A (Leucine-rich acidic nuclear protein) Length = 162 Score = 47.4 bits (111), Expect = 7e-05 Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 1/97 (1%) Frame = +2 Query: 161 ITKIENLRDLPKFTKLTLAHNKIQTISDLEELIY-CDNISVLDLQHNLIDDPKVIDEIFS 337 +T + NL L K KL L+ N+I LE L C N++ L+L+ N I D I+ + Sbjct: 51 LTSVANLPKLNKLKKLELSDNRIS--GGLEVLAEKCPNLTHLNLRGNKIKDLSTIEPL-K 107 Query: 338 KMKSLRVLYLQGNQCIKNINNYRKYTINICKHLTYLD 448 K+++L+ L L + + N+N+YR+ + LTYLD Sbjct: 108 KLENLKSLDLFNCE-VTNLNDYRENVFKLLPQLTYLD 143
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 97,201,543 Number of Sequences: 369166 Number of extensions: 1855070 Number of successful extensions: 7099 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5398 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6800 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10861812665 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)