Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_B05
(849 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P36047|SDS22_YEAST Protein phosphatases PP1 regulatory s... 57 6e-08
sp|P39687|AN32A_HUMAN Acidic leucine-rich nuclear phosphopr... 54 5e-07
sp|Q86X45|LRRC6_HUMAN Leucine-rich repeat-containing protei... 54 5e-07
sp|P45969|YNZ9_CAEEL Hypothetical protein T09A5.9 in chromo... 54 7e-07
sp|O88978|LRRC6_MOUSE Leucine-rich repeat-containing protei... 53 9e-07
sp|Q4R3F0|LRRC6_MACFA Leucine-rich repeat-containing protein 6 51 4e-06
sp|P49911|AN32A_RAT Acidic leucine-rich nuclear phosphoprot... 47 5e-05
sp|P22194|SDS22_SCHPO Protein phosphatases PP1 regulatory s... 47 5e-05
sp|O35381|AN32A_MOUSE Acidic leucine-rich nuclear phosphopr... 47 5e-05
sp||P51122_1 [Segment 1 of 2] Acidic leucine-rich nuclear p... 47 5e-05
>sp|P36047|SDS22_YEAST Protein phosphatases PP1 regulatory subunit SDS22
Length = 338
Score = 57.0 bits (136), Expect = 6e-08
Identities = 49/152 (32%), Positives = 72/152 (47%), Gaps = 3/152 (1%)
Frame = +2
Query: 2 RCLFLETNGICKLENLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENL 181
+ L +++N + K+ENLE LT L LYLS N ITKIE L
Sbjct: 206 KILSIQSNKLKKIENLEELTNLEELYLSHNF----------------------ITKIEGL 243
Query: 182 RDLPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDP-KVIDEIFSKMKSLRV 358
K T L + NK I+ LE L + N++ + N ID + + E S + L
Sbjct: 244 EKNLKLTTLDVTSNK---ITSLENLNHLSNLTDIWASFNKIDQSFESLGENLSALSRLET 300
Query: 359 LYLQGNQC-IKNINNY-RKYTINICKHLTYLD 448
+YL+GN ++N +Y RK T+N+ L +D
Sbjct: 301 IYLEGNPIQLENKTSYRRKLTMNLPPSLQKID 332
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/124 (29%), Positives = 58/124 (46%)
Frame = +2
Query: 44 NLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLRDLPKFTKLTLAHN 223
N+ LT+L L LS N I I+ I+KIENL L L L N
Sbjct: 108 NVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLKNLELGGN 167
Query: 224 KIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLYLQGNQCIKNINNY 403
K+ +I + + N+ + L N I P++I+ +K+L++L +Q N+ +K I N
Sbjct: 168 KVHSI-EPDSFEGLSNLEEIWLGKNSI--PRLIN--LHPLKNLKILSIQSNK-LKKIENL 221
Query: 404 RKYT 415
+ T
Sbjct: 222 EELT 225
>sp|P39687|AN32A_HUMAN Acidic leucine-rich nuclear phosphoprotein 32 family member A
(Potent heat-stable protein phosphatase 2A inhibitor
I1PP2A) (Acidic nuclear phosphoprotein pp32) (Cerebellar
leucine-rich acidic nuclear protein) (HLA-DR-associated
protein I) (PHAPI)
Length = 249
Score = 53.9 bits (128), Expect = 5e-07
Identities = 41/126 (32%), Positives = 69/126 (54%), Gaps = 2/126 (1%)
Frame = +2
Query: 161 ITKIENLRDLPKFTKLTLAHNKIQTISDLEELIY-CDNISVLDLQHNLIDDPKVIDEIFS 337
+T I NL L K KL L+ N++ LE L C N++ L+L N I D I+ +
Sbjct: 54 LTSIANLPKLNKLKKLELSDNRVS--GGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPL-K 110
Query: 338 KMKSLRVLYLQGNQCIKNINNYRKYTINICKHLTYLDERPVFEKDRAFAEA-FYRGGIDE 514
K+++L+ L L + + N+N+YR+ + LTYLD +K+ ++A Y G+D+
Sbjct: 111 KLENLKSLDLFNCE-VTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDD 169
Query: 515 EKKERD 532
E+++ D
Sbjct: 170 EEEDED 175
>sp|Q86X45|LRRC6_HUMAN Leucine-rich repeat-containing protein 6 (Leucine-rich
testis-specific protein) (Testis-specific leucine-rich
repeat protein)
Length = 466
Score = 53.9 bits (128), Expect = 5e-07
Identities = 53/201 (26%), Positives = 90/201 (44%), Gaps = 1/201 (0%)
Frame = +2
Query: 8 LFLETNGICKLENLEM-LTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLR 184
L L I +LE+++ +L+ LYL NLI KIEN+
Sbjct: 26 LSLHQQEIERLEHIDKWCRDLKILYLQNNLIG----------------------KIENVS 63
Query: 185 DLPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLY 364
L K L LA N I+ I +LE C+ ++ LDL N I + I + + L+ L+
Sbjct: 64 KLKKLEYLNLALNNIEKIENLEG---CEELAKLDLTVNFIGELSSIKNLQHNI-HLKELF 119
Query: 365 LQGNQCIKNINNYRKYTINICKHLTYLDERPVFEKDRAFAEAFYRGGIDEEKKERDRWVE 544
L GN C + ++YR++ + L +LD + + +R A Y I+ + +E+++
Sbjct: 120 LMGNPC-ASFDHYREFVVATLPQLKWLDGKEIEPSERIKALQDY-SVIEPQIREQEKDHC 177
Query: 545 AERERMNSSFQWLRERRAKIE 607
+R ++ Q + K E
Sbjct: 178 LKRAKLKEEAQRKHQEEDKNE 198
>sp|P45969|YNZ9_CAEEL Hypothetical protein T09A5.9 in chromosome III
Length = 326
Score = 53.5 bits (127), Expect = 7e-07
Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 41/188 (21%)
Frame = +2
Query: 8 LFLETNGICKLENLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLRD 187
L+L +N I K+ENLE LT+L+ L L N I +IE I ++E +
Sbjct: 130 LYLVSNKIEKIENLEALTQLKLLELGDNRIKKIENIGHLVNLDELFIGKNKIRQLEGVET 189
Query: 188 LPKFTKLTLAHNKIQTISDLEEL-----IYCD--------------NISVLDLQHNLI-- 304
L K + L+L N+I I ++E+L +Y N+ +LD+ +N I
Sbjct: 190 LQKLSVLSLPGNRIVKIENVEQLNNLKELYLSDQGLQDIHGVEPLTNLLLLDVANNEIKT 249
Query: 305 ---------------DDPKVID----EIFSKMKSLRVLYLQGNQCIKN-INNYRKYTINI 424
+D KV E SK+K L+ +YL+ N N N YR+ +
Sbjct: 250 FSGVERLESLNDFWANDNKVESFSEIEQLSKLKGLQTVYLERNPFYFNDTNQYRRKVMMT 309
Query: 425 CKHLTYLD 448
+T +D
Sbjct: 310 LTQVTQID 317
>sp|O88978|LRRC6_MOUSE Leucine-rich repeat-containing protein 6 (Leucine-rich
testis-specific protein) (Testis-specific leucine-rich
repeat protein)
Length = 473
Score = 53.1 bits (126), Expect = 9e-07
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +2
Query: 8 LFLETNGICKLENLEM-LTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLR 184
L L I +LE+++ +L+ LYL NLI KIEN+
Sbjct: 26 LSLHQQEIERLEHIDKWCRDLKILYLQNNLIG----------------------KIENVS 63
Query: 185 DLPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLY 364
L K L LA N I+ I +LE C+ ++ LDL N I + + + + L+ L+
Sbjct: 64 KLKKLEYLNLALNNIERIENLEG---CEWLTKLDLTVNFIGELSSVKTLTHNI-HLKELF 119
Query: 365 LQGNQCIKNINNYRKYTINICKHLTYLDERPVFEKDRAFAEAFYRGGIDEEKKERDR 535
L GN C + + YR++ + + L +LD + + +R A Y ++++ +E+++
Sbjct: 120 LMGNPC-ADFDGYRQFVVVTLQQLKWLDGKEIERSERIQALQNYT-SVEQQIREQEK 174
>sp|Q4R3F0|LRRC6_MACFA Leucine-rich repeat-containing protein 6
Length = 466
Score = 51.2 bits (121), Expect = 4e-06
Identities = 53/201 (26%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Frame = +2
Query: 8 LFLETNGICKLENLEM-LTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLR 184
L L I +LE+++ +L+ LYL NLI KIEN+
Sbjct: 26 LSLHQQEIERLEHIDKWCRDLKILYLQNNLIG----------------------KIENVS 63
Query: 185 DLPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLY 364
L K L LA N I+ I +LE C+ ++ LDL N I + I + + L+ L+
Sbjct: 64 KLKKLEYLNLALNNIEKIENLEG---CEELAKLDLTVNFIGELSSIKTLKHNI-HLKELF 119
Query: 365 LQGNQCIKNINNYRKYTINICKHLTYLDERPVFEKDRAFAEAFYRGGIDEEKKERDRWVE 544
L GN C ++YR++ + L +LD + + +R A Y I+ + +E+++
Sbjct: 120 LMGNPC-AFFDHYREFVVATLPQLKWLDGKGIEPSERIKALQEY-SIIEPQIREQEKDHC 177
Query: 545 AERERMNSSFQWLRERRAKIE 607
+R ++ Q + K E
Sbjct: 178 LKRAKLKEEAQRKHQEEDKNE 198
>sp|P49911|AN32A_RAT Acidic leucine-rich nuclear phosphoprotein 32 family member A
(Leucine-rich acidic nuclear protein)
Length = 247
Score = 47.4 bits (111), Expect = 5e-05
Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
Frame = +2
Query: 161 ITKIENLRDLPKFTKLTLAHNKIQTISDLEELIY-CDNISVLDLQHNLIDDPKVIDEIFS 337
+T I NL L K KL L+ N+I DLE L C N+ L+L N I D I+ +
Sbjct: 54 LTSISNLPKLNKLKKLELSENRIS--GDLEVLAEKCPNLKHLNLSGNKIKDLSTIEPL-K 110
Query: 338 KMKSLRVLYLQGNQCIKNINNYRKYTINICKHLTYLD--ERPVFEKDRAFAEAFYRGGID 511
K+++L+ L L + + N+N YR+ + + YLD +R E + E + +
Sbjct: 111 KLENLKSLDLFNCE-VTNLNAYRENVFKLLPQVMYLDGYDRDNKEAPDSDVEGYVEDDDE 169
Query: 512 EEKKERD 532
E++ E +
Sbjct: 170 EDEDEEE 176
>sp|P22194|SDS22_SCHPO Protein phosphatases PP1 regulatory subunit sds22
Length = 332
Score = 47.4 bits (111), Expect = 5e-05
Identities = 40/124 (32%), Positives = 57/124 (45%)
Frame = +2
Query: 8 LFLETNGICKLENLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLRD 187
L L N I ++ENL+ + L L LS N I I I +IENL
Sbjct: 87 LDLYDNLIVRIENLDNVKNLTYLDLSFNNIKTIRNINHLKGLENLFFVQNRIRRIENLEG 146
Query: 188 LPKFTKLTLAHNKIQTISDLEELIYCDNISVLDLQHNLIDDPKVIDEIFSKMKSLRVLYL 367
L + T L L NKI+ I +L+ L+ N+ L + N I E F K++ L +L +
Sbjct: 147 LDRLTNLELGGNKIRVIENLDTLV---NLEKLWVGKNKITK----FENFEKLQKLSLLSI 199
Query: 368 QGNQ 379
Q N+
Sbjct: 200 QSNR 203
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/182 (23%), Positives = 66/182 (36%), Gaps = 42/182 (23%)
Frame = +2
Query: 8 LFLETNGICKLENLEMLTELRCLYLSKNLISRIEXXXXXXXXXXXXXXXXXITKIENLRD 187
LF N I ++ENLE L L L L N I IE ITK EN
Sbjct: 131 LFFVQNRIRRIENLEGLDRLTNLELGGNKIRVIENLDTLVNLEKLWVGKNKITKFENFEK 190
Query: 188 LPKFTKLTLAHNKIQTISDLEELIYC--------------------DNISVLDLQHNLI- 304
L K + L++ N+I +L L +C +N+ +LD+ +N+I
Sbjct: 191 LQKLSLLSIQSNRITQFENLACLSHCLRELYVSHNGLTSFSGIEVLENLEILDVSNNMIK 250
Query: 305 ---------------------DDPKVIDEIFSKMKSLRVLYLQGNQCIKNINNYRKYTIN 421
+ I++ S +K L +Y +GN K + +
Sbjct: 251 HLSYLAGLKNLVELWASNNELSSFQEIEDELSGLKKLETVYFEGNPLQKTNPAVYRNKVR 310
Query: 422 IC 427
+C
Sbjct: 311 LC 312
>sp|O35381|AN32A_MOUSE Acidic leucine-rich nuclear phosphoprotein 32 family member A
(Potent heat-stable protein phosphatase 2A inhibitor
I1PP2A) (Acidic nuclear phosphoprotein pp32) (Cerebellar
leucine-rich acidic nuclear protein)
Length = 247
Score = 47.4 bits (111), Expect = 5e-05
Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
Frame = +2
Query: 161 ITKIENLRDLPKFTKLTLAHNKIQTISDLEELIY-CDNISVLDLQHNLIDDPKVIDEIFS 337
+T I NL L K KL L+ N+I DLE L C N+ L+L N I D I+ +
Sbjct: 54 LTSISNLPKLNKLKKLELSENRIS--GDLEVLAEKCPNLKHLNLSGNKIKDLSTIEPL-K 110
Query: 338 KMKSLRVLYLQGNQCIKNINNYRKYTINICKHLTYLD--ERPVFEKDRAFAEAFYRGGID 511
K+++L+ L L + + N+N YR+ + + YLD +R E + E + +
Sbjct: 111 KLENLKSLDLFNCE-VTNLNAYRENVFKLLPQVMYLDGYDRDNKEAPDSDVEGYVEDDDE 169
Query: 512 EEKKERD 532
E++ E +
Sbjct: 170 EDEDEEE 176
>sp||P51122_1 [Segment 1 of 2] Acidic leucine-rich nuclear phosphoprotein 32
family member A (Leucine-rich acidic nuclear protein)
Length = 162
Score = 47.4 bits (111), Expect = 5e-05
Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
Frame = +2
Query: 161 ITKIENLRDLPKFTKLTLAHNKIQTISDLEELIY-CDNISVLDLQHNLIDDPKVIDEIFS 337
+T + NL L K KL L+ N+I LE L C N++ L+L+ N I D I+ +
Sbjct: 51 LTSVANLPKLNKLKKLELSDNRIS--GGLEVLAEKCPNLTHLNLRGNKIKDLSTIEPL-K 107
Query: 338 KMKSLRVLYLQGNQCIKNINNYRKYTINICKHLTYLD 448
K+++L+ L L + + N+N+YR+ + LTYLD
Sbjct: 108 KLENLKSLDLFNCE-VTNLNDYRENVFKLLPQLTYLD 143
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,629,913
Number of Sequences: 369166
Number of extensions: 1411401
Number of successful extensions: 5206
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4738
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5147
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)