Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00642 (555 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 126 4e-29 sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 125 9e-29 sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 124 1e-28 sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 49 6e-06 sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin... 48 2e-05 sp|P58283|UB7I1_MOUSE E3 ubiquitin ligase TRIAD3 (Ubiquitin... 48 2e-05 sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2) 44 3e-04 sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 43 5e-04 sp|Q9WVS6|PRKN2_MOUSE Parkin (Ubiquitin E3 ligase PRKN) 43 6e-04 sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 43 6e-04
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein interacting with PKC) (Protein kinase C-binding protein beta-15) Length = 498 Score = 126 bits (316), Expect = 4e-29 Identities = 58/162 (35%), Positives = 83/162 (51%), Gaps = 3/162 (1%) Frame = +3 Query: 6 ILNDQEYEIFNDKSLLLARSKLSDIYHCKKPDCKYFGICDDSDLKHFICPICNSFNCIKY 185 +L+ ++Y+ F D + +A ++ + YHCK PDC+ + +D D+ F CP+C NC+ Sbjct: 332 LLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFED-DVNEFTCPVCTRVNCLLC 390 Query: 186 NAIHGGQTCEDFQDS---RNRPNTLDVXXXXXXXXXXXXXXCMKCPTCGCIIVKTGGCNW 356 AIH C ++QD R R + M CP C ++ K GC+W Sbjct: 391 KAIHERMNCREYQDDLAHRARNDVAAQQTTEMLRVMLQQGEAMYCPQCRIVVQKKDGCDW 450 Query: 357 VKCPQCKLELCWVLKTPRWAPKRNRDTSGVCICGVNKKPCSP 482 ++C C E+CWV K PRW P DTSG C C VN PC P Sbjct: 451 IRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHP 492
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B virus X-associated protein 4) (HBV-associated factor 4) (RING finger protein 54) Length = 500 Score = 125 bits (313), Expect = 9e-29 Identities = 57/162 (35%), Positives = 84/162 (51%), Gaps = 3/162 (1%) Frame = +3 Query: 6 ILNDQEYEIFNDKSLLLARSKLSDIYHCKKPDCKYFGICDDSDLKHFICPICNSFNCIKY 185 +L ++Y+ F D + +A ++ + YHCK PDCK + +D D+ F CP+C NC+ Sbjct: 334 LLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED-DVNEFTCPVCFHVNCLLC 392 Query: 186 NAIHGGQTCEDFQDS---RNRPNTLDVXXXXXXXXXXXXXXCMKCPTCGCIIVKTGGCNW 356 AIH C+++Q+ R + + M+CP C ++ K GC+W Sbjct: 393 KAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDW 452 Query: 357 VKCPQCKLELCWVLKTPRWAPKRNRDTSGVCICGVNKKPCSP 482 ++C C E+CWV K PRW P DTSG C C VN PC P Sbjct: 453 IRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHP 494
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3 (UbcM4-interacting protein 28) Length = 498 Score = 124 bits (312), Expect = 1e-28 Identities = 57/162 (35%), Positives = 83/162 (51%), Gaps = 3/162 (1%) Frame = +3 Query: 6 ILNDQEYEIFNDKSLLLARSKLSDIYHCKKPDCKYFGICDDSDLKHFICPICNSFNCIKY 185 +L+ ++Y+ F D + +A ++ + YHCK PDC+ + +D D+ F CP+C NC+ Sbjct: 332 LLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFED-DVNEFTCPVCTRVNCLLC 390 Query: 186 NAIHGGQTCEDFQDS---RNRPNTLDVXXXXXXXXXXXXXXCMKCPTCGCIIVKTGGCNW 356 AIH C ++QD R + + M CP C ++ K GC+W Sbjct: 391 KAIHEHMNCREYQDDLALRAQNDVAARQTTEMLKVMLQQGEAMHCPQCRIVVQKKDGCDW 450 Query: 357 VKCPQCKLELCWVLKTPRWAPKRNRDTSGVCICGVNKKPCSP 482 ++C C E+CWV K PRW P DTSG C C VN PC P Sbjct: 451 IRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHP 492
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region Length = 551 Score = 49.3 bits (116), Expect = 6e-06 Identities = 19/38 (50%), Positives = 23/38 (60%) Frame = +3 Query: 306 KCPTCGCIIVKTGGCNWVKCPQCKLELCWVLKTPRWAP 419 +CP C I K GGCN + C CK E CW+ + P WAP Sbjct: 340 ECPKCSVNIEKNGGCNHMVCSSCKYEFCWICEGP-WAP 376
>sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin conjugating enzyme 7 interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) Length = 866 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 5/121 (4%) Frame = +3 Query: 54 LARSKLSDIYHCKKPDCKYFGICDDSDLKHFICPI--CNSFNCIKYNAI---HGGQTCED 218 +A + ++ C P C + + D SD+K F CP C C K + H G TCE+ Sbjct: 594 VAAAYADELVRC--PSCSFPALLD-SDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEE 650 Query: 219 FQDSRNRPNTLDVXXXXXXXXXXXXXXCMKCPTCGCIIVKTGGCNWVKCPQCKLELCWVL 398 + D+ KC CG ++K+ GCN + C +C ++C++ Sbjct: 651 LAEKD------DIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSC-RCGAQMCYLC 703 Query: 399 K 401 + Sbjct: 704 R 704
>sp|P58283|UB7I1_MOUSE E3 ubiquitin ligase TRIAD3 (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) Length = 853 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 5/121 (4%) Frame = +3 Query: 54 LARSKLSDIYHCKKPDCKYFGICDDSDLKHFICPI--CNSFNCIKYNAI---HGGQTCED 218 +A + ++ C P C + + D SD+K F CP C C K + H G TCE+ Sbjct: 582 VAAAYADELVRC--PSCSFPALLD-SDVKRFSCPNPRCRKETCRKCQGLWKEHNGLTCEE 638 Query: 219 FQDSRNRPNTLDVXXXXXXXXXXXXXXCMKCPTCGCIIVKTGGCNWVKCPQCKLELCWVL 398 + D+ KC CG ++K+ GCN + C +C ++C++ Sbjct: 639 LAEKD------DIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSC-RCGAQMCYLC 691 Query: 399 K 401 + Sbjct: 692 R 692
>sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2) Length = 509 Score = 43.9 bits (102), Expect = 3e-04 Identities = 25/107 (23%), Positives = 39/107 (36%) Frame = +3 Query: 75 DIYHCKKPDCKYFGICDDSDLKHFICPICNSFNCIKYNAIHGGQTCEDFQDSRNRPNTLD 254 ++ C P+C+ + K IC C++ C + + T D + L Sbjct: 238 ELRFCPGPNCQIIVQSSEISAKRAICKACHTGFCFRCGMDYHAPT-----DCQVIKKWLT 292 Query: 255 VXXXXXXXXXXXXXXCMKCPTCGCIIVKTGGCNWVKCPQCKLELCWV 395 CP C I K GGCN ++C CK + CW+ Sbjct: 293 KCADDSETANYISAHTKDCPKCHICIEKNGGCNHMQCFNCKHDFCWM 339
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein) Length = 493 Score = 43.1 bits (100), Expect = 5e-04 Identities = 25/103 (24%), Positives = 34/103 (33%) Frame = +3 Query: 87 CKKPDCKYFGICDDSDLKHFICPICNSFNCIKYNAIHGGQTCEDFQDSRNRPNTLDVXXX 266 C DC + + C CN C K ++ T D L Sbjct: 228 CPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPT-----DCATIRKWLTKCAD 282 Query: 267 XXXXXXXXXXXCMKCPTCGCIIVKTGGCNWVKCPQCKLELCWV 395 CP C I K GGCN ++C +CK + CW+ Sbjct: 283 DSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWM 325
>sp|Q9WVS6|PRKN2_MOUSE Parkin (Ubiquitin E3 ligase PRKN) Length = 464 Score = 42.7 bits (99), Expect = 6e-04 Identities = 18/30 (60%), Positives = 19/30 (63%), Gaps = 2/30 (6%) Frame = +3 Query: 309 CPTCGCIIVKTGGCNWVKC--PQCKLELCW 392 CP C I K GGC +KC PQCKLE CW Sbjct: 417 CPRCNVPIEKNGGCMHMKCPQPQCKLEWCW 446
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48) Length = 492 Score = 42.7 bits (99), Expect = 6e-04 Identities = 14/29 (48%), Positives = 19/29 (65%) Frame = +3 Query: 309 CPTCGCIIVKTGGCNWVKCPQCKLELCWV 395 CP C I K GGCN ++C +CK + CW+ Sbjct: 296 CPKCNICIEKNGGCNHMQCSKCKHDFCWM 324
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,388,477 Number of Sequences: 369166 Number of extensions: 1242956 Number of successful extensions: 3091 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2955 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3064 length of database: 68,354,980 effective HSP length: 104 effective length of database: 49,142,540 effective search space used: 3931403200 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)