Planaria EST Database

DrC_00641

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00641
         (912 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q7Z4W1|DCXR_HUMAN  L-xylulose reductase (XR) (Dicarbonyl/...   212   1e-54
sp|Q91XV4|DCXR_MESAU  L-xylulose reductase (XR) (Dicarbonyl/...   208   2e-53
sp|Q91X52|DCXR_MOUSE  L-xylulose reductase (XR) (Dicarbonyl/...   206   7e-53
sp|Q920P0|DCXR_RAT  L-xylulose reductase (XR) (Dicarbonyl/L-...   205   2e-52
sp|Q8JIS3|DER_CHICK  D-erythrulose reductase                      199   9e-51
sp|Q920N9|DCXR_CAVPO  L-xylulose reductase (XR) (Dicarbonyl/...   197   3e-50
sp|Q21929|CBR2_CAEEL  Probable carbonyl reductase [NADPH] (N...   184   4e-46
sp|P08074|CBR2_MOUSE  Lung carbonyl reductase [NADPH] (NADPH...   181   3e-45
sp|Q29529|CBR2_PIG  Lung carbonyl reductase [NADPH] (NADPH-d...   176   6e-44
sp|Q8CPI3|FABG_STAES  3-oxoacyl-[acyl-carrier-protein] reduc...   120   4e-27

>sp|Q7Z4W1|DCXR_HUMAN L-xylulose reductase (XR) (Dicarbonyl/L-xylulose reductase) (Kidney
           dicarbonyl reductase) (kiDCR) (Carbonyl reductase II)
           (Sperm surface protein P34H)
          Length = 244

 Score =  212 bits (539), Expect = 1e-54
 Identities = 109/239 (45%), Positives = 154/239 (64%)
 Frame = +1

Query: 100 GKTVLVTGGSKGIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVSNIEEVKCDISKWD 279
           G+ VLVTG  KGIG+  VQ L  +GARV+++SR+     S+  E    IE V  D+  W+
Sbjct: 7   GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVREC-PGIEPVCVDLGDWE 65

Query: 280 EVNSIVKSLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQVVASDWKTR 459
                + S+ PVD LVNNAA+  L  F E+ +   D  F  N++A+I +SQ+VA     R
Sbjct: 66  ATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIAR 125

Query: 460 HIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSVNPTAILTD 639
            + G IVNVSSQ SQRAV +   YC+ K A+D +T+ MALELGP  IRVN+VNPT ++T 
Sbjct: 126 GVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTS 185

Query: 640 MGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPIDGGCWSC 816
           MG+  WS+P   + + +R+PL +  EV  VV+ I+FLL++   + TGST+P++GG W+C
Sbjct: 186 MGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC 244

>sp|Q91XV4|DCXR_MESAU L-xylulose reductase (XR) (Dicarbonyl/L-xylulose reductase) (Sperm
           antigen P26h)
          Length = 244

 Score =  208 bits (529), Expect = 2e-53
 Identities = 107/241 (44%), Positives = 152/241 (63%)
 Frame = +1

Query: 82  LNYNFTGKTVLVTGGSKGIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVSNIEEVKC 261
           ++    G+  LVTG  KGIG+  V  L  +GA V+++SR+     S+ SE    +E V  
Sbjct: 1   MDLGLAGRRALVTGAGKGIGRSTVLALQAAGAHVVAVSRTQADLDSLVSEC-PGVETVCV 59

Query: 262 DISKWDEVNSIVKSLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQVVA 441
           D++ W+     + S+ PVD LVNNAA+  L  F E+ +   D  FN N++A+I +SQ+VA
Sbjct: 60  DLADWEATEQALSSVGPVDLLVNNAAVALLQPFLEVTKEAFDMSFNVNLRAVIQVSQIVA 119

Query: 442 SDWKTRHIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSVNP 621
                R   G IVNVSSQASQRA+ +   YC+ K A+D +T+ MALELGP  IRVN+VNP
Sbjct: 120 RGMIARGAPGAIVNVSSQASQRALANHSVYCSTKGALDMLTKMMALELGPHKIRVNAVNP 179

Query: 622 TAILTDMGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPIDG 801
           T ++T MG+  WS+P   + +  R+PL +  EV  VVD I+FLL++   + TGST+P+DG
Sbjct: 180 TVVMTSMGRTNWSDPHKAKVMLDRIPLGKFAEVENVVDAILFLLSHRSNMTTGSTLPVDG 239

Query: 802 G 804
           G
Sbjct: 240 G 240

>sp|Q91X52|DCXR_MOUSE L-xylulose reductase (XR) (Dicarbonyl/L-xylulose reductase)
          Length = 244

 Score =  206 bits (524), Expect = 7e-53
 Identities = 105/241 (43%), Positives = 152/241 (63%)
 Frame = +1

Query: 82  LNYNFTGKTVLVTGGSKGIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVSNIEEVKC 261
           ++    G+  LVTG  KGIG+  V  L  +GA+V+++SR+      +  E    +E V  
Sbjct: 1   MDLGLAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVREC-PGVEPVCV 59

Query: 262 DISKWDEVNSIVKSLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQVVA 441
           D++ W+     + ++ PVD LVNNAA+  L  F E+ +   D  FN N++A+I +SQ+VA
Sbjct: 60  DLADWEATEQALSNVGPVDLLVNNAAVALLQPFLEVTKEACDTSFNVNLRAVIQVSQIVA 119

Query: 442 SDWKTRHIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSVNP 621
                R + G IVNVSSQASQRA+ +   YC+ K A+D +T+ MALELGP  IRVN+VNP
Sbjct: 120 KGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKMMALELGPHKIRVNAVNP 179

Query: 622 TAILTDMGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPIDG 801
           T ++T MG+  WS+P   + +  R+PL +  EV  VVD I+FLL+N   + TGST+P+DG
Sbjct: 180 TVVMTPMGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDTILFLLSNRSGMTTGSTLPVDG 239

Query: 802 G 804
           G
Sbjct: 240 G 240

>sp|Q920P0|DCXR_RAT L-xylulose reductase (XR) (Dicarbonyl/L-xylulose reductase)
          Length = 244

 Score =  205 bits (521), Expect = 2e-52
 Identities = 104/241 (43%), Positives = 152/241 (63%)
 Frame = +1

Query: 82  LNYNFTGKTVLVTGGSKGIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVSNIEEVKC 261
           ++    G+  LVTG  KGIG+  V  L  +GA+V+++SR+     S+  E    +E V  
Sbjct: 1   MDLGLAGRRALVTGAGKGIGRSTVLALQAAGAQVVAVSRTREDLDSLVREC-PGVEPVCV 59

Query: 262 DISKWDEVNSIVKSLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQVVA 441
           D++ W+     + ++ PVD LVNNAA+  L  F E+ +   D  FN N +A++ +SQ+VA
Sbjct: 60  DLADWEATEQALSNVGPVDLLVNNAAVATLQPFLEVTKEACDTSFNVNFRAVVQVSQIVA 119

Query: 442 SDWKTRHIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSVNP 621
                R + G IVNVSSQASQRA+ +   YC+ K A+D +T+ MALELGP  IRVN+VNP
Sbjct: 120 RGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKVMALELGPHKIRVNAVNP 179

Query: 622 TAILTDMGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPIDG 801
           T ++T MG+  WS+P   + +  R+PL +  EV  VVD I+FLL+N  ++ TGS +P+DG
Sbjct: 180 TVVMTPMGRANWSDPHKAKVMLDRIPLGKFAEVENVVDTILFLLSNRSSMTTGSALPVDG 239

Query: 802 G 804
           G
Sbjct: 240 G 240

>sp|Q8JIS3|DER_CHICK D-erythrulose reductase
          Length = 246

 Score =  199 bits (506), Expect = 9e-51
 Identities = 100/243 (41%), Positives = 158/243 (65%)
 Frame = +1

Query: 76  MTLNYNFTGKTVLVTGGSKGIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVSNIEEV 255
           M  + +F G+  LVTG  KGIG+ +   L ++GARV +LSR+     S+  E    IE +
Sbjct: 1   MEPDLSFRGRRALVTGAGKGIGRAVAVALCKAGARVTALSRTAADLESLVREC-PGIEPL 59

Query: 256 KCDISKWDEVNSIVKSLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQV 435
             D++ WD   + V +  P + LVNNAA+  L  F ++    ++  F+ N +A++++SQ+
Sbjct: 60  CLDLADWDATEAAVGAAGPFELLVNNAAVAMLQPFLQVTREAVERSFDVNFRAVLHVSQI 119

Query: 436 VASDWKTRHIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSV 615
           VA     + + G IVNVSSQASQRA+ D   YC+ K+A+D +++ MA+ELGP  IRVN+V
Sbjct: 120 VARQMIAQGLPGAIVNVSSQASQRALRDHAVYCSTKSALDMLSKVMAMELGPHKIRVNTV 179

Query: 616 NPTAILTDMGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPI 795
           NPT ++TDMG++ WS+P     + +R+PL +  EV++VV+ I+FLL++   + TGS++ +
Sbjct: 180 NPTVVMTDMGRINWSDPQKSAAMINRIPLGKFAEVDDVVNSILFLLSDKSAMTTGSSLMV 239

Query: 796 DGG 804
           DGG
Sbjct: 240 DGG 242

>sp|Q920N9|DCXR_CAVPO L-xylulose reductase (XR) (Dicarbonyl/L-xylulose reductase)
           (Protein P26h)
          Length = 244

 Score =  197 bits (502), Expect = 3e-50
 Identities = 102/241 (42%), Positives = 149/241 (61%)
 Frame = +1

Query: 82  LNYNFTGKTVLVTGGSKGIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVSNIEEVKC 261
           ++    G+  LVTG  KGIG+  V  L  +GA+V+++SR+      +  E    +E V  
Sbjct: 1   MDLGLAGRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLDDLVREC-PGVEPVCV 59

Query: 262 DISKWDEVNSIVKSLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQVVA 441
           D++ W+     + ++ P D LVNNAA+  L  F E+ +      FN N++A+I +SQ+VA
Sbjct: 60  DLADWEATEQALSNVGPADLLVNNAAVALLQPFLEVTKEACVTSFNVNLRAVIQVSQIVA 119

Query: 442 SDWKTRHIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSVNP 621
                R + G IVNVSSQASQRA+ +   YC+ K A+  +T+ MALELGP  IRVN+VNP
Sbjct: 120 KGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALYMLTKMMALELGPHKIRVNAVNP 179

Query: 622 TAILTDMGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPIDG 801
           T ++T MG+  WS+P   + +  R+PL +  EV  VVD I+FLL+N   + TGST+P+DG
Sbjct: 180 TVVMTPMGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDTILFLLSNRSGMTTGSTLPVDG 239

Query: 802 G 804
           G
Sbjct: 240 G 240

>sp|Q21929|CBR2_CAEEL Probable carbonyl reductase [NADPH] (NADPH-dependent carbonyl
           reductase)
          Length = 251

 Score =  184 bits (466), Expect = 4e-46
 Identities = 100/228 (43%), Positives = 149/228 (65%), Gaps = 4/228 (1%)
 Frame = +1

Query: 133 GIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVS---NIEEVKCDISKWDEVN-SIVK 300
           GIGK +   LA++GA+VI+ +R+     S+  E  S    I  +  D+S  +EV   ++ 
Sbjct: 20  GIGKEICLSLAKAGAQVIAFARNEANLLSLVKETTSLRYTIIPIVGDVSANEEVLFKLIV 79

Query: 301 SLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQVVASDWKTRHIEGVIV 480
              P+  LVNNA I   +  G+I +  ID  F  NV+  I I+Q+VA ++  R I+G IV
Sbjct: 80  PHFPIHGLVNNAGIATNHAIGQITQQSIDRTFAVNVRGPILIAQLVARNFVDRQIKGSIV 139

Query: 481 NVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSVNPTAILTDMGKLYWS 660
           N+SSQA+ R + +   YCA+KAA+D +TR +A ELG   IRVNSVNPT ++TDMG+  WS
Sbjct: 140 NISSQAAIRPLDNHTVYCASKAALDMVTRCLANELGSQNIRVNSVNPTVVMTDMGRDNWS 199

Query: 661 EPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPIDGG 804
           +P  K+K+  RMP++R  EV+EVV+ ++FLL++  ++ TGST+P+DGG
Sbjct: 200 DPDKKKKMLDRMPIKRFAEVDEVVNAVLFLLSDNASMTTGSTLPVDGG 247

>sp|P08074|CBR2_MOUSE Lung carbonyl reductase [NADPH] (NADPH-dependent carbonyl
           reductase) (LCR) (Adipocyte P27 protein) (AP27)
          Length = 244

 Score =  181 bits (458), Expect = 3e-45
 Identities = 98/241 (40%), Positives = 144/241 (59%)
 Frame = +1

Query: 82  LNYNFTGKTVLVTGGSKGIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVSNIEEVKC 261
           +  NF+G   LVTG  KGIG+  V+ L  SGA+V++++R+     S+  E    IE V  
Sbjct: 1   MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKEC-PGIEPVCV 59

Query: 262 DISKWDEVNSIVKSLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQVVA 441
           D+  WD     +  + PVD LVNNAA++ +  F E+ +   D  F+ N++++  +SQ+VA
Sbjct: 60  DLGDWDATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVA 119

Query: 442 SDWKTRHIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSVNP 621
            D   R + G IVNVSS  +     + +TY + K A+  +T+ MA+ELGP  IRVNSVNP
Sbjct: 120 RDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNP 179

Query: 622 TAILTDMGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPIDG 801
           T +LTDMGK   ++P    KL  R PLR+  EV +VV+ I+FLL++     +G  I +D 
Sbjct: 180 TVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDA 239

Query: 802 G 804
           G
Sbjct: 240 G 240

>sp|Q29529|CBR2_PIG Lung carbonyl reductase [NADPH] (NADPH-dependent carbonyl
           reductase) (LCR)
          Length = 244

 Score =  176 bits (447), Expect = 6e-44
 Identities = 97/241 (40%), Positives = 141/241 (58%)
 Frame = +1

Query: 82  LNYNFTGKTVLVTGGSKGIGKYLVQELAESGARVISLSRSIGTSFSIKSEAVSNIEEVKC 261
           +  NF+G   LVTG  KGIG+  V+ L  SGARV++++R+ G   S+  E    IE V  
Sbjct: 1   MQMNFSGLRALVTGAGKGIGRDTVKALHVSGARVVAVTRTNGDLVSLSQEC-PGIEPVCV 59

Query: 262 DISKWDEVNSIVKSLLPVDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQVVA 441
           D+  W+     +  + PVD LVNNAA+  +  F +  +   D  FN N++++  +SQ+VA
Sbjct: 60  DLGDWEATERALGGVGPVDLLVNNAAVALMQPFLDTTKEVFDRSFNVNLRSVFQVSQIVA 119

Query: 442 SDWKTRHIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSVNP 621
                R + G IVNVSS  S         Y + K A+  +T++MA+ELGP  IRVNSVNP
Sbjct: 120 RSMIERGVPGSIVNVSSMVSHVTYPGLAAYSSTKGAMTMLTKSMAMELGPHKIRVNSVNP 179

Query: 622 TAILTDMGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPIDG 801
           T +LT MG+   S+P    KL  R P+R+  EV +VV+ I+FLL++     +GS+I +D 
Sbjct: 180 TVVLTAMGRSVTSDPELARKLKERHPMRKFAEVEDVVNSILFLLSDRSASTSGSSIFVDA 239

Query: 802 G 804
           G
Sbjct: 240 G 240

>sp|Q8CPI3|FABG_STAES 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
          Length = 244

 Score =  120 bits (302), Expect = 4e-27
 Identities = 80/245 (32%), Positives = 128/245 (52%), Gaps = 9/245 (3%)
 Frame = +1

Query: 103 KTVLVTGGSKGIGKYLVQELAESGARVI-----SLSRSIGTSFSIKSEAVSNIEEVKCDI 267
           K+ LVTG S+GIG+ +  +LAE G  V      S  ++      IK++ V +   ++ ++
Sbjct: 3   KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVESFA-IQANV 61

Query: 268 SKWDEVNSIVKSLLP----VDYLVNNAAILKLNKFGEIGEVEIDEVFNTNVKAIINISQV 435
           +K DEV  ++K ++     VD LVNNA I K N    + E E D+V +TN+K + N  Q 
Sbjct: 62  AKGDEVKEMIKEVVSQFGSVDVLVNNAGITKDNLLMRMKEQEWDDVIDTNLKGVFNCIQK 121

Query: 436 VASDWKTRHIEGVIVNVSSQASQRAVVDFMTYCAAKAAVDAITRNMALELGPFGIRVNSV 615
           V      R   G I+N++S            Y A KA V  +T+  A EL   GI VN+V
Sbjct: 122 VTPQ-MLRQRSGAIINLTSIVGAMGNPGQANYVATKAGVIGLTKTAARELASRGITVNAV 180

Query: 616 NPTAILTDMGKLYWSEPSNKEKLTSRMPLRRLGEVNEVVDVIIFLLTNCCTLVTGSTIPI 795
            P  I++DM          K+++  ++PL+R GE  ++ + + FL ++    +TG TI +
Sbjct: 181 APGFIVSDMTNAL--SDDLKDQMLEQIPLKRFGEDTDIANTVAFLASDKAKYITGQTIHV 238

Query: 796 DGGCW 810
           +GG +
Sbjct: 239 NGGMY 243

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,866,399
Number of Sequences: 369166
Number of extensions: 1922861
Number of successful extensions: 6291
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5667
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5876
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9270587090
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00641

  1. Dr_sW_016_M13
  2. Dr_sW_016_P09
  3. Dr_sW_002_K04