Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00636 (540 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP... 140 3e-33 sp|Q05893|PPCK_ASCSU Phosphoenolpyruvate carboxykinase [GTP... 126 4e-29 sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mi... 104 1e-22 sp|P20007|PPCK_DROME Phosphoenolpyruvate carboxykinase [GTP... 100 2e-21 sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mi... 98 1e-20 sp|Q8HYZ4|PPCKC_BOVIN Phosphoenolpyruvate carboxykinase, cy... 97 2e-20 sp|P21642|PPCKM_CHICK Phosphoenolpyruvate carboxykinase, mi... 96 4e-20 sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cy... 96 6e-20 sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cy... 94 2e-19 sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cy... 93 5e-19
>sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK) Length = 619 Score = 140 bits (352), Expect = 3e-33 Identities = 67/118 (56%), Positives = 86/118 (72%) Frame = +3 Query: 57 LGHMPICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHAL 236 LGH+PI KGD+H LP VQ F+A+ A + +PR +YICDG + EA+EII KL ERG L L Sbjct: 4 LGHVPIHKGDFHLLPPKVQRFVAEKAELMRPRGIYICDGSQHEADEIIDKLIERGMLSPL 63 Query: 237 TKLENCYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPEALSDEV 410 EN YICRTDP DVARVESKT++ T DK+ TV H +G I+G WM+P++L+ E+ Sbjct: 64 KAYENNYICRTDPKDVARVESKTWMVTPDKYQTVCHTPDGIEPIMGHWMSPDSLATEL 121
>sp|Q05893|PPCK_ASCSU Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK) Length = 643 Score = 126 bits (316), Expect = 4e-29 Identities = 61/126 (48%), Positives = 86/126 (68%) Frame = +3 Query: 33 VHEVVIPHLGHMPICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLK 212 V EVV H+P+ KGD+ LPK VQ F+A+ A + KP A++ICDG ++EA+E+I + Sbjct: 17 VSEVVTHKQNHIPVIKGDFVSLPKHVQRFVAEKAELMKPSAIFICDGSQNEADELIARCV 76 Query: 213 ERGTLHALTKLENCYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPE 392 ERG L L +N Y+CRTDP DVARVESKT++ T +K+ +V H EG ++GQWM+P+ Sbjct: 77 ERGVLVPLKAYKNNYLCRTDPRDVARVESKTWMITPEKYDSVCHTPEGVKPMMGQWMSPD 136 Query: 393 ALSDEV 410 E+ Sbjct: 137 EFGKEL 142
>sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK-M) Length = 640 Score = 104 bits (260), Expect = 1e-22 Identities = 49/107 (45%), Positives = 69/107 (64%) Frame = +3 Query: 72 ICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHALTKLEN 251 + GD LP V+ F+A+ A +C+P ++ICDG E E I+ L+E+G + L K +N Sbjct: 32 VLSGDMSQLPAGVRDFVARSAHLCQPEGIHICDGTEAENTAILALLEEQGLIRKLPKYKN 91 Query: 252 CYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPE 392 C++ RTDP DVARVESKT I T + TVP + G+ G LG WM+P+ Sbjct: 92 CWLARTDPKDVARVESKTVIVTPSQRDTVPLLAGGARGQLGNWMSPD 138
>sp|P20007|PPCK_DROME Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK) Length = 647 Score = 100 bits (250), Expect = 2e-21 Identities = 48/119 (40%), Positives = 71/119 (59%) Frame = +3 Query: 54 HLGHMPICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHA 233 H+ +PI G+ L V+ F+ + +C+P ++ICDG E E +I L E GT+ Sbjct: 34 HIRGIPISYGNVDLLTTGVRAFVEEGIALCQPDQVHICDGSEQENKVLIKSLLEAGTIVP 93 Query: 234 LTKLENCYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPEALSDEV 410 L K +NC++ RT+P DVARVES+TFI T+ + T+P EG G LG W++P + V Sbjct: 94 LPKYDNCWLARTNPADVARVESRTFICTERREETIPTPVEGVKGTLGNWISPSDMDAAV 152
>sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK-M) Length = 640 Score = 97.8 bits (242), Expect = 1e-20 Identities = 46/106 (43%), Positives = 64/106 (60%) Frame = +3 Query: 72 ICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHALTKLEN 251 + GD LP ++ F+ A +C+P ++ICDG E E +T L+++G + L K N Sbjct: 32 VLSGDLGQLPTGIRDFVEHSARLCQPEGIHICDGTEAENTATLTLLEQQGLIRKLPKYNN 91 Query: 252 CYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAP 389 C++ RTDP DVARVESKT I T + TVP G+ G LG WM+P Sbjct: 92 CWLARTDPKDVARVESKTVIVTPSQRDTVPLPPGGARGQLGNWMSP 137
>sp|Q8HYZ4|PPCKC_BOVIN Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK-C) Length = 622 Score = 97.1 bits (240), Expect = 2e-20 Identities = 45/107 (42%), Positives = 71/107 (66%) Frame = +3 Query: 72 ICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHALTKLEN 251 I +G LP+AV+ F+ A +C+P ++ICDG E+E ++++ ++E G + L K +N Sbjct: 15 IVRGSLDSLPQAVRSFVESSAKLCRPDQVHICDGSEEENRQLLSHMEEEGVIKRLKKYDN 74 Query: 252 CYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPE 392 C++ TDP DVAR+ESKT I T+++ TVP K G + LG+WM+ E Sbjct: 75 CWLALTDPRDVARIESKTVIITREQRDTVPIPKNGLSQ-LGRWMSEE 120
>sp|P21642|PPCKM_CHICK Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK-M) Length = 640 Score = 96.3 bits (238), Expect = 4e-20 Identities = 44/105 (41%), Positives = 64/105 (60%) Frame = +3 Query: 96 LPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHALTKLENCYICRTDP 275 LP A + F+ + +C+PR + +CDG E+E E++ L++ G LH L K +NC++ RTDP Sbjct: 41 LPAAARDFVEEAVRLCRpreVLLCDGSEEEGKELLRGLQDDGVLHPLPKYDNCWLARTDP 100 Query: 276 DDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPEALSDEV 410 DVARVESKT + T ++ VP + LG WM+P A V Sbjct: 101 RDVARVESKTVLVTPEQSDAVPPPPPSGSPQLGNWMSPNAFQAAV 145
>sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK-C) Length = 622 Score = 95.9 bits (237), Expect = 6e-20 Identities = 46/107 (42%), Positives = 72/107 (67%) Frame = +3 Query: 72 ICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHALTKLEN 251 + +GD LP V+ FI A +C+P +++ICDG E+E +I+ + E+G + L+K EN Sbjct: 15 VIQGDLESLPPQVREFIESNAKLCQPESIHICDGSEEENKKILDIMVEQGMIKKLSKYEN 74 Query: 252 CYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPE 392 C++ T+P DVAR+ESKT I T+++ T+P K GS+ LG+WM+ E Sbjct: 75 CWLALTNPRDVARIESKTVIITQEQRDTIPIPKTGSSQ-LGRWMSEE 120
>sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK-C) Length = 622 Score = 94.0 bits (232), Expect = 2e-19 Identities = 44/107 (41%), Positives = 70/107 (65%) Frame = +3 Query: 72 ICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHALTKLEN 251 + +G LP+AV+ F+ A +C+P ++ICDG E+E +++ ++E G + L K +N Sbjct: 15 VIQGSLDSLPQAVRKFVEGNAQLCQPEYIHICDGSEEEYGQLLAHMQEEGVIRKLKKYDN 74 Query: 252 CYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPE 392 C++ TDP DVAR+ESKT I T+++ TVP K G + LG+WM+ E Sbjct: 75 CWLALTDPRDVARIESKTVIITQEQRDTVPIPKTGLSQ-LGRWMSEE 120
>sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Phosphoenolpyruvate carboxylase) (PEPCK-C) Length = 622 Score = 92.8 bits (229), Expect = 5e-19 Identities = 45/107 (42%), Positives = 70/107 (65%) Frame = +3 Query: 72 ICKGDYHYLPKAVQGFIAKWALICKPRALYICDGGEDEANEIITKLKERGTLHALTKLEN 251 + +G LP+AV+ F+ A +C+P ++ICDG E+E ++ +++E G L L K +N Sbjct: 15 VVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYDN 74 Query: 252 CYICRTDPDDVARVESKTFISTKDKHMTVPHVKEGSTGILGQWMAPE 392 C++ TDP DVAR+ESKT I T+++ TVP K G + LG+WM+ E Sbjct: 75 CWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQ-LGRWMSEE 120
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 65,508,469 Number of Sequences: 369166 Number of extensions: 1310798 Number of successful extensions: 2899 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2811 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2879 length of database: 68,354,980 effective HSP length: 104 effective length of database: 49,142,540 effective search space used: 3685690500 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)